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The Journal of Immunology, ISSN 0022-1767, 03/2005, Volume 174, Issue 5, pp. 3032 - 3040
Although blood monocytes possess significant cytotoxic activity against tumor cells, tumor-infiltrating monocytes are commonly deactivated in cancer patients.... 
IRAK-M | KAPPA-B ACTIVATION | COMPLEX | SIGNALING PATHWAY | INVOLVEMENT | ENDOTOXIN | TOLL-LIKE RECEPTORS | INNATE | IMMUNOLOGY | PROTEINS | CANCER | Protein Kinases - metabolism | Cell Communication - immunology | Protein Kinases - genetics | Toll-Like Receptor 4 | Coculture Techniques | Humans | Middle Aged | Tumor Necrosis Factor-alpha - genetics | Interleukin-1 Receptor-Associated Kinases | Hyaluronic Acid - pharmacology | Male | Monocytes - metabolism | Antibodies, Blocking - pharmacology | Monocytes - immunology | Hyaluronan Receptors - physiology | Receptors, Cell Surface - antagonists & inhibitors | RNA, Messenger - biosynthesis | Toll-Like Receptors | Membrane Glycoproteins - physiology | Membrane Glycoproteins - antagonists & inhibitors | RNA, Messenger - antagonists & inhibitors | Adult | Receptors, Cell Surface - physiology | Membrane Glycoproteins - immunology | Tumor Cells, Cultured | Protein Kinases - biosynthesis | Jurkat Cells | Macrophage Activation - immunology | Gene Expression Regulation, Neoplastic - immunology | Receptors, Interleukin-1 - biosynthesis | Receptors, Cell Surface - immunology | Up-Regulation - immunology | Down-Regulation - immunology | Cell Line, Tumor | HL-60 Cells | Hyaluronan Receptors - immunology | HeLa Cells | Tumor Necrosis Factor-alpha - biosynthesis | Index Medicus | Abridged Index Medicus
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 2003, Volume 311, Issue 2, pp. 465 - 472
The exposure of human monocytes to the gram-negative endotoxin LPS provokes them to enter a transient state in which they are refractory to further stimulation... 
IRAK-M | Endotoxin tolerance | Sepsis | PI3K | Human monocytes | CELLS | SIGNALING PATHWAYS | ACTIVATION | human monocytes | FACTOR-6 TRAF6 | TOLERANCE | MACROPHAGES | BIOCHEMISTRY & MOLECULAR BIOLOGY | FACTOR-KAPPA-B | SHOCK | INNATE IMMUNE RECOGNITION | BIOPHYSICS | endotoxin tolerance | sepsis
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2010, Volume 107, Issue 1, pp. 109 - 114
Journal Article
by Glasbey, James C and Blanco‐Colino, Ruth and Kelly, Michael and Singh, Baljit and Bhangu, Aneel and Pinkney, Thomas and Poskus, Tomas and El‐Hussuna, Alaa and Battersby, Nick J and Buchs, Nicolas C and Buskens, Christianne and Chaudri, Sanjay and Frasson, Matteo and Gallo, Gaetano and Minaya‐Bravo, Ana María and Morton, Dion and Negoi, Ionut and Nepogodiev, Dmitri and Pata, Francesco and Sánchez‐Guillén, Luis and Zmora, Oded and Perry, Rita and Magill, Laura and Altomare, Donato and Bemelman, Willem and Brown, Steven and Denost, Quentin and Knowles, Charles and Laurberg, Søren and Lefevre, Jérémie H and Möeslein, Gabriela and Pinkney, Tom and Vaizey, Carolynne and Bilali, S and Bilali, V and Salomon, M and Cillo, M and Estefania, D and Patron Uriburu, J and Ruiz, H and Farina, P and Carballo, F and Guckenheimer, S and Proud, D and Brouwer, R and Bui, A and Nguyen, B and Smart, P and Warwick, A and Theodore, J. E and Herbst, F and Birsan, T and Dauser, B and Ghaffari, S and Hartig, N and Stift, A and Argeny, S and Unger, L and Strouhal, R and Heuberger, A and Varabei, A and Lahodzich, N and Makhmudov, A and Selniahina, L and Feryn, T and Leupe, T and Maes, L and Reynvoet, E and Van Langenhove, K and Nachtergaele, M and Monami, B and Francart, D and Jehaes, C and Markiewicz, S and Weerts, J and Van Belle, K and Bomans, B and Cavenaile, V and Nijs, Y and Vertruyen, M and Pletinckx, P and Claeys, D and Defoort, B and Muysoms, F and Van Cleven, S and Lange, C and Vindevoghel, K and Wolthuis, A and Todorovic, M and Dabic, S and Kenjic, B and Lovric, S and Vidovic, J and Delibegovic, S and Mehmedovic, Z and Christiano, A and Lombardi, B and Marchiori, M and Tercioti, V and Dardanov, D and ... and 2017 European Soc Coloproctology E and 2017 European Society of Coloproctology (ESCP) collaborating group and The 2017 European Society of Coloproctology (ESCP) collaborating group
Colorectal Disease, ISSN 1462-8910, 09/2018, Volume 20, Issue S6, pp. 15 - 32
Journal Article
Oncogene, ISSN 0950-9232, 02/2017, Volume 36, Issue 25, pp. 3515 - 3527
Wild-type p53 (wtp53) is described as a tumour suppressor gene; mutations in this gene occur in many human cancers and promote oncogenic capacity. Here, we... 
TISSUE-GROWTH | F-ACTIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | HIPPO PATHWAY | YAP | T-CELL | TAZ | CELL BIOLOGY | INVASION | ORGAN GROWTH | ONCOLOGY | GENETICS & HEREDITY | ACTIN ORGANIZATION | WASP-INTERACTING PROTEIN | Cytoskeletal Proteins - genetics | Humans | Male | Intracellular Signaling Peptides and Proteins - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Phosphoproteins - metabolism | Proto-Oncogene Proteins c-akt - genetics | Tumor Suppressor Protein p53 - genetics | Breast Neoplasms - metabolism | Phosphorylation - genetics | Glioblastoma - genetics | MCF-7 Cells | Neoplastic Stem Cells - metabolism | Tumor Suppressor Proteins - genetics | HEK293 Cells | Neoplastic Stem Cells - pathology | Cytoskeletal Proteins - metabolism | Female | Glioblastoma - metabolism | Protein Stability | Proto-Oncogene Proteins c-akt - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Tumor Suppressor Proteins - metabolism | Signal Transduction | Tumor Suppressor Protein p53 - metabolism | Phosphoproteins - genetics | Transcription Factors - genetics | Phosphatidylinositol 3-Kinases - genetics | Transcription Factors - metabolism | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Glioblastoma - pathology | Adaptor Proteins, Signal Transducing - genetics | Mutation | Adaptor Proteins, Signal Transducing - metabolism | Tumor suppressor genes | Genetic aspects | Cellular signal transduction | Health aspects | Stem cells | Cancer cells | Cell proliferation | Cell culture | Astrocytes | p53 Protein | Genes | Glioblastoma | AKT2 protein | Breast cancer | 1-Phosphatidylinositol 3-kinase | Yes-associated protein | Signal transduction | Suspension culture | CD44 antigen | Recycling | Cancer | Tumors | Index Medicus
Journal Article
by Bhangu, Aneel and Minaya‐Bravo, Ana María and Gallo, Gaetano and Glasbey, James C and Kamarajah, Sivesh and Pinkney, Thomas and El‐Hussuna, Alaa and Battersby, Nick J and Buchs, Nicolas C and Buskens, Christianne and Chaudri, Sanjay and Frasson, Matteo and Glasbey, James and Morton, Dion and Negoi, Ionut and Nepogodiev, Dmitri and Pata, Francesco and Sánchez‐Guillén, Luis and Singh, Baljit and Zmora, Oded and Perry, Rita and Magill, Laura and Altomare, Donato and Bemelman, Willem and Brown, Steven and Denost, Quentin and Knowles, Charles and Laurberg, Søren and Lefevre, Jérémie H and Möeslein, Gabriela and Pinkney, Tom and Vaizey, Carolynne and Bilali, S and Bilali, V and Salomon, M and Cillo, M and Estefania, D and Patron Uriburu, J and Ruiz, H and Farina, P and Carballo, F and Guckenheimer, S and Proud, D and Brouwer, R and Bui, A and Nguyen, B and Smart, P and Warwick, A and Theodore, J. E and Herbst, F and Birsan, T and Dauser, B and Ghaffari, S and Hartig, N and Stift, A and Argeny, S and Unger, L and Strouhal, R and Heuberger, A and Varabei, A and Lahodzich, N and Makhmudov, A and Selniahina, L and Feryn, T and Leupe, T and Maes, L and Reynvoet, E and Van Langenhove, K and Nachtergaele, M and Monami, B and Francart, D and Jehaes, C and Markiewicz, S and Weerts, J and Van Belle, K and Bomans, B and Cavenaile, V and Nijs, Y and Vertruyen, M and Pletinckx, P and Claeys, D and Defoort, B and Muysoms, F and Van Cleven, S and Lange, C and Vindevoghel, K and Wolthuis, A and Todorovic, M and Dabic, S and Kenjic, B and Lovric, S and Vidovic, J and Delibegovic, S and Mehmedovic, Z and Christiano, A and Lombardi, B and Marchiori, M and Tercioti, V and Dardanov, D and Petkov, P and ... and 2017 European Soc Coloproctology E and 2017 European Society of Coloproctology (ESCP) collaborating group and The 2017 European Society of Coloproctology (ESCP) collaborating group
Colorectal Disease, ISSN 1462-8910, 09/2018, Volume 20, Issue S6, pp. 33 - 46
Journal Article