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American Journal of Physiology-Cell Physiology, ISSN 0363-6143, 02/2014, Volume 306, Issue 4, pp. C320 - C321
Journal Article
Journal Article
Cancer Science, ISSN 1347-9032, 02/2014, Volume 105, Issue 2, pp. 202 - 210
Effective molecular target drugs that improve therapeutic efficacy with fewer adverse effects for esophageal cancer are highly anticipated. Poly(ADP‐ribose)... 
RNF8 | esophageal cancer | DNA repair | poly(ADP‐ribose) polymerase inhibitor | γ‐H2AX | γ-H2AX | Esophageal cancer | Poly(ADP-ribose) polymerase inhibitor | H2AX | ENDOSCOPIC MUCOSAL RESECTION | STRAND BREAK REPAIR | MUTANT-CELLS | SENSITIVITY | FANCONI-ANEMIA | CANCER | DEFICIENCY | poly(ADP-ribose) polymerase inhibitor | ONCOLOGY | ATM | HOMOLOGOUS RECOMBINATION | RADIOTHERAPY | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Humans | Molecular Sequence Data | G2 Phase - drug effects | DNA-Binding Proteins - metabolism | MCF-7 Cells | Esophageal Neoplasms - metabolism | Esophageal Squamous Cell Carcinoma | DNA Damage - drug effects | Carcinoma, Squamous Cell - enzymology | DNA Repair - drug effects | DNA-Binding Proteins - genetics | Mutation - genetics | Piperazines - adverse effects | Piperazines - pharmacology | Poly(ADP-ribose) Polymerase Inhibitors | Cell Division - drug effects | Ubiquitin-Protein Ligases | Phthalazines - pharmacology | Esophageal Neoplasms - enzymology | Carcinoma, Squamous Cell - drug therapy | Histones - genetics | Mutation - drug effects | Esophageal Neoplasms - genetics | Cell Cycle Checkpoints - drug effects | Cell Line, Tumor | Histones - metabolism | Esophageal Neoplasms - drug therapy | Phthalazines - adverse effects | Squamous cell carcinoma | Ligases | DNA damage | Development and progression | Sugars | Tumors | Monosaccharides | Growth rate | Toxicity | Cancer therapies | Comet assay | Defects | Ribose | Cell cycle | Tumorigenesis | Endoscopy | Ubiquitin-protein ligase | Deoxyribonucleic acid--DNA | Polyclonal antibodies | Cell survival | Poly(ADP-ribose) polymerase | Tumor cell lines | Double-strand break repair | Esophagus | Medical prognosis | Cell lines | Biomarkers | Software | Mutation | Index Medicus | Original
Journal Article
Journal Article
Cancer Science, ISSN 1347-9032, 12/2016, Volume 107, Issue 12, pp. 1818 - 1824
GBS‐01, an extract from the fruit of Arctium lappa L. is an orally administered drug rich in arctigenin, which has been reported to exert antitumor activity by... 
Arctigenin | phase I trial | pancreatic cancer | gemcitabine | chemotherapy | natural anticancer compound | CELLS | FOLFIRINOX | TOLERANCE | IDENTIFICATION | TUMORS | THERAPY | ONCOLOGY | S-1 | STARVATION | Humans | Middle Aged | Deoxycytidine - pharmacology | Drug Resistance, Neoplasm | Male | Tomography, X-Ray Computed | Biomarkers, Tumor | Pancreatic Neoplasms - drug therapy | Antineoplastic Agents, Phytogenic - administration & dosage | Deoxycytidine - therapeutic use | Neoplasm Metastasis | Adult | Female | Pancreatic Neoplasms - mortality | Antineoplastic Agents, Phytogenic - therapeutic use | Antineoplastic Agents, Phytogenic - pharmacokinetics | Antineoplastic Agents, Phytogenic - adverse effects | Pancreatic Neoplasms - pathology | Neoplasm Recurrence, Local | Treatment Outcome | Maximum Tolerated Dose | Survival Analysis | Aged | Drug Monitoring | Neoplasm Staging | Deoxycytidine - analogs & derivatives | Antimitotic agents | Chemotherapy | Hyperglycemia | Pancreatic cancer | Clinical trials | Product development | Bilirubin | Antineoplastic agents | Cancer | Gemcitabine | g-Glutamyltransferase | Toxicity | Oral administration | Metastasis | Bioavailability | Glucose | Cancer therapies | Patients | Fruits | Herbal medicine | Tomography | Antitumor activity | Hypoxia | Pharmacokinetics | Pharmaceutical industry | Drug dosages | Tumors | Index Medicus | Original
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2010, Volume 76, Issue 1, pp. 277 - 286
Purpose To verify the usefulness of our developed beam ON-LINE positron emission tomography (PET) system mounted on a rotating gantry port (BOLPs-RGp) for... 
Radiology | Hematology, Oncology and Palliative Medicine | Beam ON-LINE PET system on rotating gantry port (BOLPs-RGp) | Dose–volume delivery guided proton therapy (DGPT) | Target nuclear fragment reaction | Dose-volume delivery guided proton therapy (DGPT) | DISTRIBUTIONS | POSITRON-EMISSION-TOMOGRAPHY | ONCOLOGY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | VERIFICATION | DELIVERY | Prostatic Neoplasms - radiotherapy | Reproducibility of Results | Brain Neoplasms - diagnostic imaging | Head and Neck Neoplasms - diagnostic imaging | Humans | Lung Neoplasms - radiotherapy | Protons - therapeutic use | Male | Technology, Radiologic - instrumentation | Positron-Emission Tomography - methods | Technology, Radiologic - methods | Neoplasms - diagnostic imaging | Online Systems | Positron-Emission Tomography - instrumentation | Equipment Design | Liver Neoplasms - diagnostic imaging | Rotation | Radiography | Algorithms | Liver Neoplasms - radiotherapy | Prostatic Neoplasms - diagnostic imaging | Lung Neoplasms - diagnostic imaging | Neoplasms - radiotherapy | Medical colleges | Pets | Research | Oncology, Experimental | Cancer | TOMOGRAPHY | HEAD | DIGESTIVE SYSTEM | EMISSION COMPUTED TOMOGRAPHY | LUNGS | NERVOUS SYSTEM | FERMIONS | MALE GENITALS | TUMOR CELLS | ANIMAL CELLS | MEDICINE | THERAPY | GLANDS | POSITRON COMPUTED TOMOGRAPHY | RADIOLOGY AND NUCLEAR MEDICINE | RADIOTHERAPY | BRAIN | RADIOLOGY | PROSTATE | DIAGNOSTIC TECHNIQUES | NEOPLASMS | CENTRAL NERVOUS SYSTEM | PROTONS | COMPUTERIZED TOMOGRAPHY | ELEMENTARY PARTICLES | NUCLEAR MEDICINE | NUCLEONS | ACCURACY | ORGANS | DISEASES | RESPIRATORY SYSTEM | LIVER | NECK | BARYONS | BODY | HADRONS
Journal Article
Journal Article
British Journal of Cancer, ISSN 0007-0920, 11/2017, Volume 117, Issue 10, pp. 1450 - 1458
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2018, Volume 13, Issue 6, p. e0198219
Arctigenin is evaluated for antitumor efficacy in patients with pancreatic cancer. It has an inhibitory activity on mitochondrial complex I .Therefore, plasma... 
SPRAGUE-DAWLEY RATS | NUTRIENT DEPRIVATION | CELLS | THERAPY | METABOLISM | PATHWAY | TOLERANCE | GLUCOSE | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | STARVATION | Area Under Curve | Lactic Acid - blood | Gluconeogenesis - drug effects | Humans | Carcinoma, Adenosquamous - drug therapy | Deoxycytidine - pharmacology | Drug Resistance, Neoplasm | Liver - physiopathology | Furans - therapeutic use | Lignans - therapeutic use | Oxidative Phosphorylation - drug effects | Pancreatic Neoplasms - drug therapy | Furans - pharmacokinetics | Arctium - chemistry | Antineoplastic Agents, Phytogenic - therapeutic use | Antineoplastic Agents, Phytogenic - pharmacokinetics | Drugs, Chinese Herbal - therapeutic use | Kidney - physiopathology | Pancreatic Neoplasms - blood | Kaplan-Meier Estimate | Biomarkers - blood | Mitochondria - drug effects | Carcinoma, Adenosquamous - blood | Carcinoma, Pancreatic Ductal - blood | Carcinoma, Pancreatic Ductal - drug therapy | Drugs, Chinese Herbal - pharmacokinetics | Lignans - pharmacokinetics | Cell Line, Tumor | Plant Extracts - therapeutic use | Deoxycytidine - analogs & derivatives | Drug Screening Assays, Antitumor | Lactates | Development and progression | Care and treatment | Genetic aspects | Identification and classification | Pancreatic cancer | Plasma | Diabetic retinopathy | Gemcitabine | Liver | Clinical trials | Oncology | Colorimetry | Kinases | Cancer therapies | Anticancer properties | Electron transport chain | Mitochondria | Rodents | Surgery | Pharmaceutical industry | NADH-ubiquinone oxidoreductase | Statistical analysis | Pharmacology | Metabolism | Patients | Chemotherapy | Biomarkers | Antitumor activity | Hypoxia | Lactic acid | Respiration | Alzheimers disease | Pharmacokinetics | Cancer
Journal Article