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Chemical Communications, ISSN 1359-7345, 2018, Volume 54, Issue 69, pp. 9647 - 9650
Herein we report a new class of G-quadruplex stabilising ligands, multicarbazoles, which display high G-quadruplex DNA selectivity in the presence of 250 times... 
TELOMERE TARGETING AGENTS | DNA STRUCTURES | CANCER-CELLS | DESIGN | LIGANDS | RECOGNITION | STABILIZATION | CHAINS | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | Ligands | Selectivity | Piperidine | Deoxyribonucleic acid--DNA
Journal Article
Chemical Science, ISSN 2041-6520, 2017, Volume 8, Issue 4, pp. 2923 - 2930
Tools for editing the genome and epigenome have revolutionised the field of molecular biology and represent a new frontier in targeted therapeutic... 
POLYMERS | CELLS | GENE DELIVERY | TRANSFECTION | MASPIN | PAMAM DENDRIMERS | IN-VIVO | CLICK-CHEMISTRY | BIOMEDICAL APPLICATIONS | EFFICIENCY | CHEMISTRY, MULTIDISCIPLINARY | Platforms | Synthesis (chemistry) | Efficiency | Editing | Packaging | Strategy | Genomes | Polymers
Journal Article
CHEMICAL SCIENCE, ISSN 2041-6520, 09/2019, Volume 10, Issue 33, pp. 7718 - 7727
Aberrant gene expression is a hallmark of cancer. Although transcription is traditionally considered 'undruggable', the development of CRISPR-associated... 
SYSTEM | CELLS | ACTIVATION | GENE | IN-VIVO | CCN6 | WISP3 | CARCINOMAS | CHEMISTRY, MULTIDISCIPLINARY | MASPIN EXPRESSION | DELIVERY
Journal Article
ISSN 2041-6520, 6/2019, Volume 1, Issue 24, pp. 6174 - 6183
Ultra-high molecular weight (UHMW, M n > 1000 kDa) polymeric drift control adjuvants (DCAs) for agricultural spraying are prone to mechanical degradation and... 
Journal Article
ISSN 1359-7345, 8/2018, Volume 54, Issue 69, pp. 9647 - 965
Herein we report a new class of G-quadruplex stabilising ligands, multicarbazoles, which display high G-quadruplex DNA selectivity in the presence of 250 times... 
Journal Article
ISSN 2041-6520, 8/2019, Volume 1, Issue 33, pp. 7718 - 7727
Aberrant gene expression is a hallmark of cancer. Although transcription is traditionally considered 'undruggable', the development of CRISPR-associated... 
Journal Article
Nanomedicine: Nanotechnology, Biology, and Medicine, ISSN 1549-9634, 08/2019, Volume 20, pp. 102003 - 102003
Triple negative breast cancers (TNBC) are aggressive malignancies for which chemotherapy is the only treatment option. Many TNBC acquire chemotherapy... 
RGD sequences | Polymeric nanoparticles | Peptides | ENGRAILED 1 | Triple negative breast cancer | MEDICINE, RESEARCH & EXPERIMENTAL | BETA-3 INTEGRIN | PBX | NANOSCIENCE & NANOTECHNOLOGY | PACLITAXEL | PHASE-III TRIAL | HOX | INHIBITION | DNA | RESISTANCE | ELECTROSTATICS | Index Medicus
Journal Article
Chemical Science, ISSN 2041-6520, 01/2019, Volume 10, Issue 33, pp. 7718 - 7727
Aberrant gene expression is a hallmark of cancer. Although transcription is traditionally considered ‘undruggable’, the development of CRISPR-associated... 
Connective tissues | CRISPR | Toxicity | Abnormalities | Genes | Biocompatibility | Activation | Gene expression | Growth factors | Cancer | Tumors
Journal Article
ISSN 1759-9954, 12/2017, Volume 9, Issue 1, pp. 6 - 68
The effect of visible LED power ( λ max = 402 nm, 451 nm) on kinetics and control of direct photoactivation RAFT polymerisations of acrylamide and... 
Journal Article
ISSN 1759-9954, 6/2017, Volume 8, Issue 24, pp. 372 - 3711
Accurate and reliable analysis of polymers by GPC is vital in the field of controlled radical polymerisation. Often, water-soluble polymers are analysed by... 
Journal Article
ISSN 2041-6520, 3/2017, Volume 8, Issue 4, pp. 2923 - 293
Tools for editing the genome and epigenome have revolutionised the field of molecular biology and represent a new frontier in targeted therapeutic... 
Journal Article
Physics Reports, ISSN 0370-1573, 11/2013, Volume 532, Issue 4, pp. 119 - 244
Journal Article
Chemical Science, ISSN 2041-6520, 4/2017, Volume 8, Issue 4, pp. 2923 - 2930
Tools for editing the genome and epigenome have revolutionised the field of molecular biology and represent a new frontier in targeted therapeutic... 
Chemistry
Journal Article
06/2019, Volume 9, Issue 35, pp. 253 - 257
Advances in the field of genome engineering demand the development of efficient non-viral transfection agents capable of delivering multiple distinct nucleic... 
Journal Article
Green Chemistry, ISSN 1463-9262, 2006, Volume 8, Issue 5, pp. 417 - 432
Until recently the spectacular developments in nanotechnology have been with little regard to their potential effect on human health and the environment. There... 
GOLD NANOPARTICLES | GREEN & SUSTAINABLE SCIENCE & TECHNOLOGY | INTRATRACHEAL INSTILLATION | OXIDATIVE STRESS | PULMONARY TOXICITY | SEMICONDUCTOR QUANTUM DOTS | WALL CARBON NANOTUBES | ULTRAFINE PARTICLES | BORON-NITRIDE | BIOMEDICAL APPLICATIONS | TITANIUM-DIOXIDE | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 2009, Volume 131, Issue 45, pp. 16338 - 16339
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2018, Volume 1767, pp. 241 - 254
The potential impact of CRISPR/Cas9, TALE, and zinc finger technology is immense, both with respect to their use as tools for understanding the roles and... 
Plasmid | CRISPR | TALE | Dendrimer | Co-transfection | Zinc finger | Polymer | Gene technology | Non-viral | Cell Line | Animals | Transfection - methods | Humans | CRISPR-Cas Systems | Halogenation | Click Chemistry - methods | Dendrimers - chemistry | Dendrimers - chemical synthesis | Azides - chemical synthesis | Azides - chemistry | Transfection - economics | Index Medicus
Journal Article