Pediatric Transplantation, ISSN 1397-3142, 12/2019, Volume 23, Issue 8, p. n/a
The ITR serves as an international database for centers around the world to contribute to current knowledge about intestinal transplant outcomes. Led by the...
graft rejection | pediatric transplantation | registries | intestinal transplantation | short bowel syndrome | pediatrics
graft rejection | pediatric transplantation | registries | intestinal transplantation | short bowel syndrome | pediatrics
Journal Article
Clinical transplants, ISSN 0890-9016, 2016, Volume 32, pp. 23 - 30
Poor long-term graft survival remains a major problem in the field of organ transplantation. This could be attributed at least in part, to the lack of reliable...
kidney | graft rejection | cytokines | chemokines | transplantation | Immunosuppression | Cytokines | Humans | Biomarkers | Graft Rejection | Graft Survival | Kidney Transplantation
kidney | graft rejection | cytokines | chemokines | transplantation | Immunosuppression | Cytokines | Humans | Biomarkers | Graft Rejection | Graft Survival | Kidney Transplantation
Journal Article
Clinical transplants, ISSN 0890-9016, 2016, Volume 32, pp. 13 - 22
The results from continued research regarding the role of anti-human leukocyte antigen (anti-HLA) antibodies and donor-specific antibodies (DSA) in...
donor-specific antibodies | allograft rejection | transplantation | Humans | Antibodies | Graft Rejection | Graft Survival | Kidney Transplantation | HLA Antigens | Isoantibodies | Tissue Donors | Transplantation, Homologous
donor-specific antibodies | allograft rejection | transplantation | Humans | Antibodies | Graft Rejection | Graft Survival | Kidney Transplantation | HLA Antigens | Isoantibodies | Tissue Donors | Transplantation, Homologous
Journal Article
Clinical transplants, ISSN 0890-9016, 2014, pp. 125 - 129
In the last few years, there have been studies published on serial testing and longitudinal analysis of anti-human leukocyte antigen (anti-HLA) antibodies. The...
Liver Transplantation | Graft Rejection - prevention & control | Humans | Risk Factors | HLA Antigens - immunology | Graft Survival | Treatment Outcome | Biomarkers - blood | Lung Transplantation - adverse effects | Isoantibodies - blood | Immunity, Humoral | Time Factors | Graft Rejection - immunology | Histocompatibility | Pancreas Transplantation - adverse effects | Kidney Transplantation - adverse effects
Liver Transplantation | Graft Rejection - prevention & control | Humans | Risk Factors | HLA Antigens - immunology | Graft Survival | Treatment Outcome | Biomarkers - blood | Lung Transplantation - adverse effects | Isoantibodies - blood | Immunity, Humoral | Time Factors | Graft Rejection - immunology | Histocompatibility | Pancreas Transplantation - adverse effects | Kidney Transplantation - adverse effects
Journal Article
Clinical transplants, ISSN 0890-9016, 2014, pp. 27 - 32
Heart transplantation in the United States remains an important option for those with heart failure. Survival rates over the last 25 years have improved with...
Heart Failure - surgery | Predictive Value of Tests | United States - epidemiology | Heart Transplantation - trends | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Child, Preschool | Infant | Male | Young Adult | Time Factors | Aged, 80 and over | Adult | Female | Registries | Heart Failure - diagnosis | Child | Heart Transplantation - mortality | Heart Failure - mortality | Histocompatibility Testing | Graft Rejection - prevention & control | Risk Factors | Kaplan-Meier Estimate | Heart Transplantation - adverse effects | Treatment Outcome | Tissue and Organ Procurement - organization & administration | Tissue and Organ Procurement - trends | Adolescent | Aged | Graft Rejection - immunology | Graft Survival - drug effects | Histocompatibility
Heart Failure - surgery | Predictive Value of Tests | United States - epidemiology | Heart Transplantation - trends | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Child, Preschool | Infant | Male | Young Adult | Time Factors | Aged, 80 and over | Adult | Female | Registries | Heart Failure - diagnosis | Child | Heart Transplantation - mortality | Heart Failure - mortality | Histocompatibility Testing | Graft Rejection - prevention & control | Risk Factors | Kaplan-Meier Estimate | Heart Transplantation - adverse effects | Treatment Outcome | Tissue and Organ Procurement - organization & administration | Tissue and Organ Procurement - trends | Adolescent | Aged | Graft Rejection - immunology | Graft Survival - drug effects | Histocompatibility
Journal Article
6.
There is a Road, No Simple Highway: Envisioning a Path to Better Long-Term Organ Transplant Survival
Clinical transplants, ISSN 0890-9016, 2015, Volume 31, p. 203
The current half-life of a transplanted organ has not improved in a very long time. Historical reports on the causes of allograft failure have pointed to a...
Journal Article
Clinical transplants, ISSN 0890-9016, 2009, pp. 323 - 337
Despite the substantial effects and promise of bortezomib-based regimens, there is still much to be learned. Finding an effective approach to removing...
Graft Rejection - drug therapy | Bortezomib | Heart Transplantation - immunology | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Combined Modality Therapy | Pyrazines - therapeutic use | Boronic Acids - therapeutic use | Plasmapheresis | Immunoglobulins, Intravenous - therapeutic use | Lung Transplantation - immunology | Antilymphocyte Serum - therapeutic use | Adult | Female | Aged | Graft Rejection - immunology | Safety | Kidney Transplantation - immunology | Protease Inhibitors - therapeutic use
Graft Rejection - drug therapy | Bortezomib | Heart Transplantation - immunology | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Combined Modality Therapy | Pyrazines - therapeutic use | Boronic Acids - therapeutic use | Plasmapheresis | Immunoglobulins, Intravenous - therapeutic use | Lung Transplantation - immunology | Antilymphocyte Serum - therapeutic use | Adult | Female | Aged | Graft Rejection - immunology | Safety | Kidney Transplantation - immunology | Protease Inhibitors - therapeutic use
Journal Article
Clinical transplants, ISSN 0890-9016, 2015, Volume 31, p. 139
In recent years, there have been multiple studies published on longitudinal and retrospective analysis of anti-human leukocyte antigen (anti-HLA) antibodies....
Journal Article
Clinical transplants, ISSN 0890-9016, 2013, pp. 313 - 317
In the last 10 years, many reports on the impact of antibodies against human leukocyte antigens (HLA) have been published. Now, in 2014, the overwhelming...
Antibody Specificity | Graft Rejection - epidemiology | Graft Rejection - prevention & control | Humans | HLA Antigens - immunology | Isoantibodies - immunology | Seroepidemiologic Studies | Graft Rejection - immunology | Kidney Transplantation - statistics & numerical data | Incidence
Antibody Specificity | Graft Rejection - epidemiology | Graft Rejection - prevention & control | Humans | HLA Antigens - immunology | Isoantibodies - immunology | Seroepidemiologic Studies | Graft Rejection - immunology | Kidney Transplantation - statistics & numerical data | Incidence
Journal Article
10.
An Update on Cardiac Transplantation in the United States Based on an Analysis of the UNOS Registry
Clinical transplants, ISSN 0890-9016, 2015, Volume 31, p. 27
Cardiac transplantation remains a viable option for those with end-stage heart disease. In the last few years, the number of heart transplants has begun to...
Journal Article
Clinical transplants, ISSN 0890-9016, 2012, pp. 219 - 223
The purpose of immunosuppression in patients receiving a solid organ transplant is to prevent both acute and chronic rejection, while avoiding the...
Graft Rejection - drug therapy | Transplantation Immunology - immunology | Humans | Immunosuppressive Agents - therapeutic use | Transplantation Immunology - drug effects | Isoantibodies - immunology | Organ Transplantation
Graft Rejection - drug therapy | Transplantation Immunology - immunology | Humans | Immunosuppressive Agents - therapeutic use | Transplantation Immunology - drug effects | Isoantibodies - immunology | Organ Transplantation
Journal Article
Clinical transplants, ISSN 0890-9016, 2012, p. 225
Journal Article
Clinical transplants, ISSN 0890-9016, 2014, pp. 13 - 26
Advances in immunosuppression (IS) agents and strategies have resulted in reduced rejection rates and improved survival outcomes after liver transplantation....
United States - epidemiology | Immunosuppression - trends | Liver Transplantation - adverse effects | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Liver Transplantation - trends | Immunosuppression - mortality | Immunosuppression - adverse effects | Time Factors | Graft Rejection - mortality | Adult | Female | Registries | Retrospective Studies | Graft Rejection - prevention & control | Risk Factors | Liver Transplantation - mortality | Treatment Outcome | Tissue and Organ Procurement - organization & administration | Disease-Free Survival | Tissue and Organ Procurement - trends | Immunosuppressive Agents - adverse effects | Graft Rejection - immunology | Graft Survival - drug effects
United States - epidemiology | Immunosuppression - trends | Liver Transplantation - adverse effects | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Liver Transplantation - trends | Immunosuppression - mortality | Immunosuppression - adverse effects | Time Factors | Graft Rejection - mortality | Adult | Female | Registries | Retrospective Studies | Graft Rejection - prevention & control | Risk Factors | Liver Transplantation - mortality | Treatment Outcome | Tissue and Organ Procurement - organization & administration | Disease-Free Survival | Tissue and Organ Procurement - trends | Immunosuppressive Agents - adverse effects | Graft Rejection - immunology | Graft Survival - drug effects
Journal Article
Hepatology, ISSN 0270-9139, 03/2019, Volume 69, Issue 3, pp. 1273 - 1286
Journal Article
Clinical transplants, ISSN 0890-9016, 2013, pp. 1 - 11
The continuously growing number of patients of advanced age with end-stage renal disease demands adequate treatment in the form of renal transplantation....
Kidney Failure, Chronic - mortality | Predictive Value of Tests | United States - epidemiology | Age Distribution | Kidney Failure, Chronic - surgery | Humans | Middle Aged | Risk Factors | Graft Survival | Male | Registries - statistics & numerical data | Aged, 80 and over | Adult | Female | Kidney Transplantation - mortality | Aged | Retrospective Studies
Kidney Failure, Chronic - mortality | Predictive Value of Tests | United States - epidemiology | Age Distribution | Kidney Failure, Chronic - surgery | Humans | Middle Aged | Risk Factors | Graft Survival | Male | Registries - statistics & numerical data | Aged, 80 and over | Adult | Female | Kidney Transplantation - mortality | Aged | Retrospective Studies
Journal Article
Clinical transplants, ISSN 0890-9016, 2011, pp. 319 - 325
Based on our knowledge that donor specific anti-HLA antibodies (DSA) are a major cause of allograft loss, determining how to monitor patients for DSA and how...
Histocompatibility Testing | Graft Rejection - prevention & control | Humans | Immunosuppressive Agents - therapeutic use | Monitoring, Immunologic | HLA Antigens - immunology | Graft Survival | Treatment Outcome | Evidence-Based Medicine | Transplantation Tolerance - drug effects | Isoantibodies - blood | Histocompatibility - drug effects | Time Factors | Organ Transplantation - adverse effects | Graft Rejection - immunology | Desensitization, Immunologic
Histocompatibility Testing | Graft Rejection - prevention & control | Humans | Immunosuppressive Agents - therapeutic use | Monitoring, Immunologic | HLA Antigens - immunology | Graft Survival | Treatment Outcome | Evidence-Based Medicine | Transplantation Tolerance - drug effects | Isoantibodies - blood | Histocompatibility - drug effects | Time Factors | Organ Transplantation - adverse effects | Graft Rejection - immunology | Desensitization, Immunologic
Journal Article
Transplantation, ISSN 0041-1337, 12/2008, Volume 86, Issue 12, pp. 1754 - 1761
Background. Current antihumoral therapies in transplantation and autoimmune disease do not target the mature antibody-producing plasma cell. Bortezomib is a...
B cell | Alloantibodies | Bortezomib | Proteasome inhibitor | Plasma cell | SURGERY | APOPTOSIS | ACTIVATION | DENDRITIC CELLS | PHASE-2 | IMMUNOLOGY | MULTIPLE-MYELOMA CELLS | REVERSAL | TRANSPLANTATION | RENAL-ALLOGRAFT REJECTION | REFRACTORY MYELOMA | PROTEASOME INHIBITOR BORTEZOMIB | FK-506 | Acute Disease | Kidney Transplantation - pathology | United States | Graft Rejection - prevention & control | Humans | Immunosuppressive Agents - therapeutic use | Boronic Acids - adverse effects | Pyrazines - therapeutic use | Thrombocytopenia - chemically induced | Boronic Acids - therapeutic use | Isoantibodies - blood | Kidney Transplantation - physiology | Biopsy | Pyrazines - adverse effects | Creatinine - blood | Isoantibodies - immunology | Protease Inhibitors - adverse effects | Immunosuppressive Agents - adverse effects | Kidney Transplantation - immunology | Protease Inhibitors - therapeutic use | Paresthesia - chemically induced | United States Food and Drug Administration | Index Medicus
B cell | Alloantibodies | Bortezomib | Proteasome inhibitor | Plasma cell | SURGERY | APOPTOSIS | ACTIVATION | DENDRITIC CELLS | PHASE-2 | IMMUNOLOGY | MULTIPLE-MYELOMA CELLS | REVERSAL | TRANSPLANTATION | RENAL-ALLOGRAFT REJECTION | REFRACTORY MYELOMA | PROTEASOME INHIBITOR BORTEZOMIB | FK-506 | Acute Disease | Kidney Transplantation - pathology | United States | Graft Rejection - prevention & control | Humans | Immunosuppressive Agents - therapeutic use | Boronic Acids - adverse effects | Pyrazines - therapeutic use | Thrombocytopenia - chemically induced | Boronic Acids - therapeutic use | Isoantibodies - blood | Kidney Transplantation - physiology | Biopsy | Pyrazines - adverse effects | Creatinine - blood | Isoantibodies - immunology | Protease Inhibitors - adverse effects | Immunosuppressive Agents - adverse effects | Kidney Transplantation - immunology | Protease Inhibitors - therapeutic use | Paresthesia - chemically induced | United States Food and Drug Administration | Index Medicus
Journal Article
Clinical transplants, ISSN 0890-9016, 2013, pp. 31 - 44
The annual number of adult heart transplantations in the United States is still low due to a lack of donor organs. Median long-term survival has been improved...
Heart Failure - surgery | Heart-Assist Devices - statistics & numerical data | United States - epidemiology | Age Distribution | Humans | Middle Aged | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Graft Survival | Male | Young Adult | Registries - statistics & numerical data | Adolescent | Aging | Adult | Female | Aged | Heart Transplantation - mortality | Heart Failure - mortality
Heart Failure - surgery | Heart-Assist Devices - statistics & numerical data | United States - epidemiology | Age Distribution | Humans | Middle Aged | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Graft Survival | Male | Young Adult | Registries - statistics & numerical data | Adolescent | Aging | Adult | Female | Aged | Heart Transplantation - mortality | Heart Failure - mortality
Journal Article
Clinical transplants, ISSN 0890-9016, 2011, pp. 333 - 336
This section of Clinical Transplants 2011 has presented outcomes-based evidence that supports the use of single antigen bead testing for detection of donor...
Histocompatibility Testing | Graft Rejection - prevention & control | Humans | Monitoring, Immunologic | HLA Antigens - immunology | Graft Survival | Treatment Outcome | Evidence-Based Medicine | Isoantibodies - blood | Transplantation Tolerance | Time Factors | Organ Transplantation - adverse effects | Graft Rejection - immunology | Histocompatibility
Histocompatibility Testing | Graft Rejection - prevention & control | Humans | Monitoring, Immunologic | HLA Antigens - immunology | Graft Survival | Treatment Outcome | Evidence-Based Medicine | Isoantibodies - blood | Transplantation Tolerance | Time Factors | Organ Transplantation - adverse effects | Graft Rejection - immunology | Histocompatibility
Journal Article
20.
Full Text
Incidence and impact of de Novo donor-specific alloantibody in primary renal allografts
Transplantation, ISSN 0041-1337, 02/2013, Volume 95, Issue 3, pp. 410 - 417
Background. To date, limited information is available describing the incidence and impact of de novo donor-specific anti-human leukocyte antigen (HLA)...
Allograft survival | Donor-specific antibodies | Epidemiology | Human leukocyte antigen | SURVIVAL | SURGERY | HLA-SPECIFIC ANTIBODIES | POSTTRANSPLANT | INJURY | PROSPECTIVE TRIAL | GRAFT FAILURE | IMMUNOLOGY | TRANSPLANTATION | HUMAN-LEUKOCYTE ANTIGEN | KIDNEY-TRANSPLANT FAILURE | ANTIBODY-MEDIATED REJECTION | ASSOCIATION | Follow-Up Studies | Histocompatibility Testing | Humans | Middle Aged | HLA Antigens - immunology | Male | Transplantation, Homologous | Incidence | Isoantibodies - blood | Young Adult | Graft Rejection - epidemiology | Time Factors | Adolescent | Aged, 80 and over | Adult | Female | Aged | Retrospective Studies | Graft Rejection - immunology | Tissue Donors | Kidney Transplantation - immunology | Longitudinal Studies | Antibodies | Clinical trials | Alloantibodies | Histocompatibility antigen HLA | Leukocytes | Kidney transplantation
Allograft survival | Donor-specific antibodies | Epidemiology | Human leukocyte antigen | SURVIVAL | SURGERY | HLA-SPECIFIC ANTIBODIES | POSTTRANSPLANT | INJURY | PROSPECTIVE TRIAL | GRAFT FAILURE | IMMUNOLOGY | TRANSPLANTATION | HUMAN-LEUKOCYTE ANTIGEN | KIDNEY-TRANSPLANT FAILURE | ANTIBODY-MEDIATED REJECTION | ASSOCIATION | Follow-Up Studies | Histocompatibility Testing | Humans | Middle Aged | HLA Antigens - immunology | Male | Transplantation, Homologous | Incidence | Isoantibodies - blood | Young Adult | Graft Rejection - epidemiology | Time Factors | Adolescent | Aged, 80 and over | Adult | Female | Aged | Retrospective Studies | Graft Rejection - immunology | Tissue Donors | Kidney Transplantation - immunology | Longitudinal Studies | Antibodies | Clinical trials | Alloantibodies | Histocompatibility antigen HLA | Leukocytes | Kidney transplantation
Journal Article
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