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1. Full Text Metabolomics in immunology research
by Everts, Bart
Methods in Molecular Biology, ISSN 1064-3745, 2018, Volume 1730, pp. 29 - 42
There is a growing appreciation that metabolic processes and individual metabolites can shape the function of immune cells and thereby play important roles in... 
Immunometabolism | NMR | Cellular metabolism | Immune cells | Mass spectrometry | Metabolite tracing | Immune System Diseases - metabolism | Macrophages - metabolism | Magnetic Resonance Spectroscopy | T-Lymphocytes - metabolism | Immune System - metabolism | Humans | Mass Spectrometry | Metabolomics - methods | Index Medicus
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2. Full Text The Business of War: The Peirce School in World War I
by Bart Everts
Pennsylvania History, ISSN 0031-4528, 10/2017, Volume 84, Issue 4, pp. 488 - 503
Founded in 1865, The Peirce School of Business Administration taught a variety of business-related courses as well as teacher training classes. The school was... 
Business administration | Soldiers | War effort | Military training | Business schools | Military preparedness | Educational administration | Graduates | War | School enrollment | Women | Higher education | World War I | Peirce School of Business Administration | Business education | Philadelphia | Homefront
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3. Full Text Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation
by Huang, Stanley Ching-Cheng and Smith, Amber M and Everts, Bart and Colonna, Marco and Pearce, Erika L and Pearce, Edward J and Schilling, Joel D
Immunity, ISSN 1074-7613, 10/2016, Volume 45, Issue 4, pp. 817 - 830
Macrophage activation status is intrinsically linked to metabolic remodeling. Macrophages stimulated by interleukin 4 (IL-4) to become alternatively (or, M2)... 
cytokine signaling | growth-factor signaling | macrophage | metabolism | cancer immunity | type 2 immunity | MAMMALIAN TARGET | PHOSPHORYLATION | KINASE | AKT | COMPLEX 2 | DIFFERENTIATION | IMMUNOLOGY | POLARIZATION | CANCER | T-CELLS | MTOR | Macrophage Activation - physiology | Macrophages - physiology | TOR Serine-Threonine Kinases - metabolism | Interleukin-4 - metabolism | Interferon Regulatory Factors - metabolism | Macrophage Colony-Stimulating Factor - metabolism | Phosphatidylinositol 3-Kinases - metabolism | STAT6 Transcription Factor - metabolism | Mechanistic Target of Rapamycin Complex 2 | Multiprotein Complexes - metabolism | Macrophages - metabolism | Animals | Signal Transduction - physiology | Mice | Proto-Oncogene Proteins c-akt - metabolism | Glucose metabolism | Medical colleges | Interleukins | Immunotherapy | Physiological aspects | Macrophage colony stimulating factor | Glucose | Macrophages | Nematoda | Fatty acids | Dextrose | Synthesis | Bone marrow | Flow cytometry | Kinases | Metabolism | Gene expression | Cloning | Index Medicus
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4. Full Text Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization
by Jha, Abhishek K and Huang, Stanley Ching-Cheng and Sergushichev, Alexey and Lampropoulou, Vicky and Ivanova, Yulia and Loginicheva, Ekaterina and Chmielewski, Karina and Stewart, Kelly M and Ashall, Juliet and Everts, Bart and Pearce, Edward J and Driggers, Edward M and Artyomov, Maxim N
Immunity, ISSN 1074-7613, 03/2015, Volume 42, Issue 3, pp. 419 - 430
Macrophage polarization involves a coordinated metabolic and transcriptional rewiring that is only partially understood. By using an integrated high-throughput... 
IMMUNITY | CELLS | ACTIVATION | INFLAMMATION | NITRIC-OXIDE | INNATE | GLYCOSYLATION | IMMUNOLOGY | Glutamine - deficiency | Aspartic Acid - immunology | Argininosuccinic Acid - immunology | Mitochondria - immunology | Chemokine CCL22 - immunology | Metabolic Networks and Pathways - immunology | Mitochondria - genetics | Argininosuccinic Acid - metabolism | Gene Regulatory Networks - immunology | Isocitrate Dehydrogenase - immunology | Macrophages - immunology | Uridine Diphosphate N-Acetylglucosamine - metabolism | Nitric Oxide - immunology | Macrophages - classification | Aspartate Aminotransferase, Mitochondrial - immunology | Interleukin-6 - genetics | Signal Transduction | Gene Expression Regulation | Isocitrate Dehydrogenase - genetics | Glycosylation | Mitochondria - metabolism | Macrophages - cytology | Immunity, Innate | Citric Acid Cycle | Uridine Diphosphate N-Acetylglucosamine - immunology | Chemokine CCL22 - genetics | Macrophages - metabolism | Metabolic Networks and Pathways - genetics | Animals | Interleukin-6 - immunology | Transcription, Genetic - immunology | Aspartic Acid - metabolism | Mice | Aspartate Aminotransferase, Mitochondrial - genetics | Nitric Oxide - metabolism | Enzymes | Tracers (Biology) | Analysis | Nitric oxide | Physiological aspects | Aspartate | Genetic aspects | Genetic transcription | Macrophages | Glutamine | Metabolites | Rodents | Scientific imaging | Metabolism | Labeling | Mass spectrometry | Index Medicus
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5. Full Text Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages
by Huang, Stanley Ching-Cheng and Everts, Bart and Ivanova, Yulia and O'Sullivan, David and Nascimento, Marcia and Smith, Amber M and Beatty, Wandy and Love-Gregory, Latisha and Lam, Wing Y and O'Neill, Christina M and Yan, Cong and Du, Hong and Abumrad, Nada A and Urban, Joseph F and Artyomov, Maxim N and Pearce, Erika L and Pearce, Edward J
Nature Immunology, ISSN 1529-2908, 2014, Volume 15, Issue 9, pp. 846 - 855
Alternative (M2) activation of macrophages driven via the a-chain of the receptor for interleukin 4 (IL-4R alpha) is important for immunity to parasites, wound... 
REGULATES LIPID-METABOLISM | INFLAMMATION | IN-VIVO | DISEASE | GENE-EXPRESSION | ATHEROSCLEROSIS | MICE | DIFFERENTIATION | IMMUNOLOGY | ACID LIPASE | FOAM CELLS | Macrophage Activation - immunology | Humans | Oxidative Phosphorylation | Oxygen Consumption | Transcriptome | CD36 Antigens - immunology | Lipolysis - immunology | Receptors, Interleukin-4 - immunology | Sterol Esterase - immunology | Interleukin-4 - immunology | Signal Transduction - immunology | Animals | Cell Respiration | Helminthiasis, Animal - immunology | Mice | Fatty Acids - metabolism | Lysosomes - immunology | Macrophages - immunology | Lysosomes | Research | Macrophages | Cell transformation | Lipolysis | Index Medicus
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6. Full Text Mitochondrial Respiratory Capacity Is a Critical Regulator of CD8+ T Cell Memory Development
by van der Windt, Gerritje J.W and Everts, Bart and Chang, Chih-Hao and Curtis, Jonathan D and Freitas, Tori C and Amiel, Eyal and Pearce, Erika L and Pearce, Edward J
Immunity, ISSN 1074-7613, 01/2012, Volume 36, Issue 1, pp. 68 - 78
CD8 T cells undergo major metabolic changes upon activation, but how metabolism influences the establishment of long-lived memory T cells after infection... 
SIGNAL-TRANSDUCTION | OXIDATIVE-PHOSPHORYLATION | HOMEOSTASIS | METABOLISM | COMPLEX-I | AEROBIC GLYCOLYSIS | IL-15 | PROLIFERATION | IMMUNOLOGY | EXPRESSION | CUTTING EDGE | CD8-Positive T-Lymphocytes - cytology | Mitochondria - enzymology | Oxidation-Reduction | Mice, Inbred C57BL | Mitochondria - metabolism | CD8-Positive T-Lymphocytes - enzymology | Animals | Flow Cytometry | Models, Biological | Carnitine O-Palmitoyltransferase - metabolism | Interleukin-15 - metabolism | Cell Respiration - physiology | Immunologic Memory | Mice | CD8-Positive T-Lymphocytes - immunology | Fatty Acids - metabolism | Real-Time Polymerase Chain Reaction | Survival analysis | Bioenergetics | Cytokines | Rodents | Acidification | Infections | Glucose | Metabolism | Index Medicus
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7. Full Text Micro(RNAs)managing Macrophage Polarization During Schistosomiasis
by Everts, Bart
EBioMedicine, ISSN 2352-3964, 11/2016, Volume 13, Issue C, pp. 33 - 34
MEDICINE, RESEARCH & EXPERIMENTAL | MICRORNAS | Macrophages - metabolism | Macrophage Activation - genetics | Cytokines - metabolism | Macrophage Activation - immunology | Humans | Gene Expression Regulation | Schistosomiasis - parasitology | Schistosomiasis - genetics | MicroRNAs - genetics | Schistosomiasis - immunology | Macrophages - immunology | Index Medicus
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8. Full Text Klf4 Expression in Conventional Dendritic Cells Is Required for T Helper 2 Cell Responses
by Tussiwand, Roxane and Everts, Bart and Grajales-Reyes, Gary E and Kretzer, Nicole M and Iwata, Arifumi and Bagaitkar, Juhi and Wu, Xiaodi and Wong, Rachel and Anderson, David A and Murphy, Theresa L and Murphy, Kenneth M and Pearce, Edward J
Immunity, ISSN 1074-7613, 05/2015, Volume 42, Issue 5, pp. 916 - 928
The two major lineages of classical dendritic cells (cDCs) express and require either IRF8 or IRF4 transcription factors for their development and function.... 
DUST MITE ALLERGEN | TRANSCRIPTION FACTORS | SIGNALING CONTROLS | CYTOKINE RESPONSES | SCHISTOSOMA-MANSONI | IN-VIVO | INNATE LYMPHOID-CELLS | IMMUNOLOGY | MONOCYTE DIFFERENTIATION | LANGERHANS CELLS | TRANSGENIC MICE | Toxoplasmosis - immunology | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Schistosomiasis mansoni - immunology | Dendritic Cells - immunology | Mice, Inbred C57BL | Cells, Cultured | Interferon Regulatory Factors - genetics | Th2 Cells - cytology | Th2 Cells - immunology | Herpes Simplex - immunology | Enterobacteriaceae Infections - immunology | Antigens, Helminth - immunology | Interferon Regulatory Factors - immunology | Animals | Kruppel-Like Transcription Factors - metabolism | Gene Deletion | Asthma - immunology | Pyroglyphidae | Mice | Kruppel-Like Transcription Factors - genetics | Dendritic Cells - metabolism | Disease Models, Animal | Antiviral agents | Dendritic cells | T cells | Health aspects | Confidence intervals | Transcription factors | Software | Infections | Gene expression | Immune system | Index Medicus
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9. Full Text CD8 memory T cells have a bioenergetic advantage that underlies their rapid recall ability
by Gerritje J. W. van der Windt and David O'Sullivan and Bart Everts and Stanley Ching-Cheng Huang and Michael D. Buck and Jonathan D. Curtis and Chih-Hao Chang and Amber M. Smith and Teresa Ai and Brandon Faubert and Russell G. Jones and Edward J. Pearce and Erika L. Pearce
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2013, Volume 110, Issue 35, pp. 14336 - 14341
A characteristic of memory T (TM) cells is their ability to mount faster and stronger responses to reinfection than naïve T (TN) cells do in response to an... 
T lymphocytes | Cell growth | Mitochondria | Energy metabolism | Cellular metabolism | Cytokines | Memory | Glycolysis | Cultured cells | Reinfection | Metabolism | Lymphocytes | SIGNAL-TRANSDUCTION | EFFECTOR | OXIDATIVE-PHOSPHORYLATION | lymphocytes | HEXOKINASE | MULTIDISCIPLINARY SCIENCES | IN-VIVO | RESPIRATORY CAPACITY | MITOCHONDRIA | metabolism | DIFFERENTIATION | NAIVE | CD8-Positive T-Lymphocytes - cytology | Animals | Energy Metabolism | Lymphocyte Activation | Immunologic Memory | Mice | CD8-Positive T-Lymphocytes - immunology | Mitochondrial Size | Cell interaction | Immunology | Physiological aspects | Research | T cells | Health aspects | Adenosine triphosphate | Phosphorylation | T cell receptors | Oxidation | Cells | Adenosine triphosphatase | Index Medicus | Biological Sciences
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10. Full Text Guidelines for the use of flow cytometry and cell sorting in immunological studies
by Cossarizza, Anea and Chang, Hyun-Dong and Radbruch, Aneas and Anä, Immanuel and Annunziato, Francesco and Bacher, Petra and Barnaba, Vincenzo and Battistini, Luca and Bauer, Wolfgang M and Baumgart, Sabine and Becher, Burkhard and Beisker, Wolfgang and Berek, Claudia and Blanco, Alfonso and Borsellino, Giovanna and Boulais, Philip E and Brinkman, Ryan R and Büscher, Martin and Busch, Dirk H and Bushnell, Timothy P and Cao, Xuetao and Cavani, Anea and Chattopadhyay, Pratip K and Cheng, Qingyu and Chow, Sue and Clerici, Mario and Cooke, Anne and Cosma, Antonio and Cosmi, Lorenzo and Cumano, Ana and Dang, Van Duc and Davies, Derek and de Biasi, Sara and del Zotto, Genny and Della Bella, Silvia and Dellabona, Paolo and Deniz, Günnur and Dessing, Mark and Diefenbach, Aneas and Di Santo, James and Dieli, Francesco and Dolf, Aneas and Donnenberg, Vera S and Dörner, Thomas and Ehrhardt, Götz R. A and Endl, Elmar and Engel, Pablo and Engelhardt, Britta and Esser, Charlotte and Everts, Bart and Falk, Christine S and Fehniger, Todd A and Filby, Anew and Fillatreau, Simon and Follo, Marie and Förster, Irmgard and Foster, John and Foulds, Gemma A and Frenette, Paul S and Galbraith, David and Garbi, Natalio and García-Godoy, Maria Dolores and Ghoreschi, Kamran and Gibellini, Lara and Goettlinger, Christoph and Goodyear, Carl S and Gori, Anea and Grogan, Jane and Gross, Mor and Grützkau, Aneas and Grummitt, Daryl and Hahn, Jonas and Hammer, Quirin and Hauser, Anja E and Haviland, David L and Hedley, David and Herrera, Guadalupe and Herrmann, Martin and Hiepe, Falk and Holland, Tristan and Hombrink, Pleun and Houston, Jessica P and Hoyer, Bimba F and Huang, Bo and Hunter, Christopher A and Iannone, Anna and Jäck, Hans-Martin and Jávega, Beatriz and Jonjic, Stipan and Juelke, Kerstin and Jung, Steffen and Kaiser, Toralf and Kalina, Tomas and Keller, Baerbel and Khan, Srijit and Kienhöfer, Deborah and Kroneis, Thomas and Kunkel, Désirée and Kurts, Christian and Kvistborg, Pia and ... and Medicinska fakulteten and Linköpings universitet and Institutionen för klinisk och experimentell medicin and Avdelningen för Kirurgi, Ortopedi och Onkologi
European journal of immunology, ISSN 0014-2980, 2017, Volume 47, Issue 10, pp. 1584 - 1797
The classical model of hematopoiesis established in the mouse postulates that lymphoid cells originate from a founder population of common lymphoid... 
CHEMOKINE RECEPTOR EXPRESSION | NATURAL-KILLER-CELLS | HLA CLASS-I | ROR-GAMMA-T | CIRCULATING ENDOTHELIAL-CELLS | HEMATOPOIETIC STEM-CELLS | ANTIGEN-SPECIFIC CD4(+) | INNATE LYMPHOID-CELLS | IMMUNOLOGY | CD8(+) T-CELLS | BLOOD MONONUCLEAR-CELLS | Guidelines as Topic | Cell Proliferation | RNA - analysis | Cell Separation | Immunologic Techniques | Humans | Immunophenotyping | False Positive Reactions | Animals | Flow Cytometry | T-Lymphocytes - cytology | DNA - analysis | Software | Research Design | Quality Control | Flow cytometry | Cytometry | Immunology | Index Medicus | Life Sciences | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
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