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1. Full Text Mitochondrial Steve: paternal inheritance of mitochondria in humans
by Bromham, Lindell and Eyre-Walker, Adam and Smith, Noel H and Maynard Smith, John
Trends in Ecology & Evolution, ISSN 0169-5347, 2003, Volume 18, Issue 1, pp. 2 - 4
Mitochondrial DNA is the primary tool in the investigation of recent evolutionary history, particularly for uncovering human origins and expansion. Maternal... 
ISLAND MELANESIA | EVOLUTIONARY BIOLOGY | EVOLUTION | HUMAN-POPULATION | GENETICS & HEREDITY | ECOLOGY | DNA RECOMBINATION
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2. Full Text The zebrafish reference genome sequence and its relationship to the human genome
by Howe, K and Clark, M.D and Torroja, C.F and Torrance, J and Berthelot, C and Muffato, M and Collins, J.E and Humphray, S and McLaren, K and Matthews, L and McLaren, S and Sealy, I and Caccamo, M and Churcher, C and Scott, C and Barrett, J.C and Koch, R and Rauch, G.J and White, S and Chow, W and Kilian, B and Quintais, L.T and Guerra-Assuncao, J.A and Zhou, Y and Gu, Y and Yen, J and Vogel, J.H and Eyre, T and Redmond, S and Banerjee, R and Chi, J and Fu, B and Langley, E and Maguire, S.F and Laird, G.K and Lloyd, D and Kenyon, E and Donaldson, S and Sehra, H and Almeida-King, J and Loveland, J and Trevanion, S and Jones, M and Quail, M and Willey, D and Hunt, A and Burton, J and Sims, S and McLay, K and Plumb, B and Davis, J and Clee, C and Oliver, K and Clark, R and Riddle, C and Elliot, D and Threadgold, G and Harden, G and Ware, D and Mortimore, B and Kerry, G and Heath, P and Phillimore, B and Tracey, A and Corby, N and Dunn, M and Johnson, C and Wood, J and Clark, S and Pelan, S and Griffiths, G and Smith, M and Glithero, R and Howden, P and Barker, N and Stevens, C and Harley, J and Holt, K and Panagiotidis, G and Lovell, J and Beasley, H and Henderson, C and Gordon, D and Auger, K and Wright, D and Collins, J and Raisen, C and Dyer, L and Leung, K and Robertson, L and Ambridge, K and Leongamornlert, D and McGuire, S and Gilderthorp, R and Griffiths, C and Manthravadi, D and Nichol, S and Barker, G and Whitehead, S and Kay, M and ...
Nature, ISSN 0028-0836, 2013, Volume 496, Issue 7446, pp. 498 - 503
Zebrafish have become a popular organism for the study of vertebrate gene function. The virtually transparent embryos of this species, and the ability to... 
DANIO-RERIO | EVOLUTION | GENE | MULTIDISCIPLINARY SCIENCES | FISH | VERTEBRATES | DUPLICATION | MUTATIONS | MAP | REVEALS | Conserved Sequence - genetics | Sex Determination Processes - genetics | Genomics | Humans | Molecular Sequence Annotation | Genome - genetics | Genes - genetics | Male | Genome, Human - genetics | Zebrafish - genetics | Meiosis - genetics | Pseudogenes - genetics | Reference Standards | Animals | Chromosomes - genetics | Female | Zebrafish Proteins - genetics | Evolution, Molecular | Physiological aspects | Genetic aspects | Research | Zebra fish | Human genetics | Proteins | Zebrafish | Genetics | Chromosomes | Genes | Index Medicus
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3. Full Text Genetics of rheumatoid arthritis contributes to biology and drug discovery
by Okada, Yukinori and Wu, Di and Trynka, Gosia and Raj, Towfique and Terao, Chikashi and Ikari, Katsunori and Kochi, Yuta and Ohmura, Koichiro and Suzuki, Akari and Yoshida, Shinji and Graham, Robert R and Manoharan, Arun and Ortmann, Ward and Bhangale, Tushar and Denny, Joshua C and Carroll, Robert J and Eyler, Anne E and Greenberg, Jeffrey D and Kremer, Joel M and Pappas, Dimitrios A and Jiang, Lei and Yin, Jian and Ye, Lingying and Su, Ding-Feng and Yang, Jian and Xie, Gang and Keystone, Ed and Westra, Harm-Jan and Esko, Tõnu and Metspalu, Anes and Zhou, Xuezhong and Gupta, Namrata and Mirel, Daniel and Stahl, Eli A and Diogo, Dorothée and Cui, Jing and Liao, Katherine and Guo, Michael H and Myouzen, Keiko and Kawaguchi, Takahisa and Coenen, Marieke J. H and van Riel, Piet L. C. M and van de Laar, Mart A. F. J and Guchelaar, Henk-Jan and Huizinga, Tom W. J and Dieudé, Philippe and Mariette, Xavier and Bridges, S. Louis and Zhernakova, Alexana and Toes, Rene E. M and Tak, Paul P and Miceli-Richard, Corinne and Bang, So-Young and Lee, Hye-Soon and Martin, Javier and Gonzalez-Gay, Miguel A and Roiguez-Roiguez, Luis and Rantapää-Dahlqvist, Solbritt and Arlestig, Lisbeth and Choi, Hyon K and Kamatani, Yoichiro and Galan, Pilar and Lathrop, Mark and Eyre, Steve and Bowes, John and Barton, Anne and de Vries, Niek and Moreland, Larry W and Criswell, Lindsey A and Karlson, Elizabeth W and Taniguchi, Atsuo and Yamada, Ryo and Kubo, Michiaki and Liu, Jun S and Bae, Sang-Cheol and Worthington, Jane and Padyukov, Leonid and Klareskog, Lars and Gregersen, Peter K and Raychaudhuri, Soumya and Stranger, Barbara E and de Jager, Philip L and Franke, Lude and Visscher, Peter M and Brown, Matthew A and Yamanaka, Hisashi and Mimori, Tsuneyo and Takahashi, Atsushi and Xu, Huji and Behrens, Timothy W and Siminovitch, Katherine A and Momohara, Shigeki and Matsuda, Fumihiko and Yamamoto, Kazuhiko and Plenge, Robert M and Lee, Annette and Martin, Paul and Stahl, Eli and Viatte, Sebastien and McAllister, Kate and ... and RACI Consortium and GARNET Consortium and RACI consortium and GARNET consortium and the RACI consortium and the GARNET consortium and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Umeå universitet and Reumatologi
Nature, ISSN 0028-0836, 2014, Volume 506, Issue 7488, pp. 376 - +
A major challenge in human genetics is to devise a systematic strategy to integrate disease-associated variants with diverse genomic and biological data sets... 
RECEPTOR INHIBITION | VARIANTS | MULTIDISCIPLINARY SCIENCES | DISEASE | SUSCEPTIBILITY | RISK | LOCI | IDENTIFICATION | TRAITS | GENOME-WIDE ASSOCIATION | RESOURCE | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Humans | Asian Continental Ancestry Group - genetics | Computational Biology | Male | Drug Repositioning | Molecular Targeted Therapy | Drug Discovery | Case-Control Studies | Arthritis, Rheumatoid - pathology | Mice, Knockout | Arthritis, Rheumatoid - metabolism | Arthritis, Rheumatoid - genetics | Animals | Arthritis, Rheumatoid - drug therapy | Alleles | Polymorphism, Single Nucleotide - genetics | Female | Hematologic Neoplasms - genetics | Mice | Hematologic Neoplasms - metabolism | Quantitative trait loci | Genome-wide association studies | Rheumatoid arthritis | Genetic research | Genetic aspects | Research | Human genetics | Disease | Hematology | Cytokines | Genes | Genomics | Genomes | Meta-analysis | Proteins | Confidence intervals | Hypotheses | Quality control | Epigenetics | Population | Genetics | Health risk assessment | Asians | Cancer | Index Medicus | Rheumatology and Autoimmunity | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Reumatologi och inflammation | Virtual screening | Klinisk medicin
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4. Full Text Capture Hi-C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci
by Martin, Paul and McGovern, Amanda and Orozco, Gisela and Duffus, Kate and Yarwood, Annie and Schoenfelder, Stefan and Cooper, Nicholas J and Barton, Anne and Wallace, Chris and Fraser, Peter and Worthington, Jane and Eyre, Steve
Nature Communications, ISSN 2041-1723, 11/2015, Volume 6, Issue 1, pp. 10069 - 10069
Genome-wide association studies have been tremendously successful in identifying genetic variants associated with complex diseases. The majority of association... 
SUSCEPTIBILITY LOCI | CONFORMATION | EXPRESSION | MULTIDISCIPLINARY SCIENCES | GENOME | HIGH-RESOLUTION | Genetic variance | Biotechnology | Lymphocytes B | FOXO1 protein | Genes | Cell lines | Genomes | Lymphocytes T | Single-nucleotide polymorphism | Autoimmune diseases | Index Medicus
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5. Full Text Rare variants and autoimmune disease
by Jonathan Massey and Steve Eyre
Briefings in Functional Genomics, ISSN 2041-2649, 09/2014, Volume 13, Issue 5, p. 392
  Cardiovascular disease (CVD) is a leading cause of mortality and morbidity in the Western world. Large genome-wide association studies (GWASs) of coronary... 
Genotype & phenotype | Risk assessment | Genes | Cardiomyocytes | Lipids | Cardiovascular disease
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6. Full Text High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis
by Eyre, Steve and Bowes, John and Diogo, Dorothee and Lee, Annette and Barton, Anne and Martin, Paul and Zhernakova, Alexana and Stahl, Eli and Viatte, Sebastien and McAllister, Kate and Amos, Christopher I and Padyukov, Leonid and Toes, Rene E. M and Huizinga, Tom W. J and Wijmenga, Cisca and Trynka, Gosia and Franke, Lude and Westra, Harm-Jan and Alfredsson, Lars and Hu, Xinli and Sandor, Cynthia and de Bakker, Paul I. W and Davila, Sonia and Khor, Chiea Chuen and Heng, Khai Koon and Anews, Robert and Edkins, Sarah and Hunt, Sarah E and Langford, Cordelia and Symmons, Deborah and Concannon, Pat and Onengut-Gumuscu, Suna and Rich, Stephen S and Deloukas, Panos and Gonzalez-Gay, Miguel A and Roiguez-Roiguez, Luis and Arlsetig, Lisbeth and Martin, Javier and Rantapaa-Dahlqvist, Solbritt and Plenge, Robert M and Raychaudhuri, Soumya and Klareskog, Lars and Gregersen, Peter K and Worthington, Jane and Biol Rheumatoid Arthrit Genetics G and Wellcome Trust Case Control Consor and Wellcome Trust Case Control Consortium and Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Umeå universitet and Reumatologi
Nature Genetics, ISSN 1061-4036, 12/2012, Volume 44, Issue 12, pp. 1336 - 1340
Using the Immunochip custom SNP array, which was designed for dense genotyping of 186 loci identified through genome-wide association studies (GWAS), we... 
INTERLEUKIN-6 RECEPTOR | RISK LOCI | METAANALYSIS | GENETICS & HEREDITY | CORONARY-HEART-DISEASE | EXPRESSION | ASSOCIATION | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Oligonucleotide Array Sequence Analysis | Autoantibodies - blood | Humans | Male | Genetic Loci | Chromosome Mapping - instrumentation | Arthritis, Rheumatoid - genetics | Chromosome Mapping - methods | Female | Polymorphism, Single Nucleotide | Autoantibodies - genetics | Rheumatoid arthritis | Physiological aspects | Genetic aspects | Disease susceptibility | Single nucleotide polymorphisms | Research | Chromosomes | Studies | Medical research | Autoimmune diseases | Index Medicus | Rheumatology and Autoimmunity | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Reumatologi och inflammation
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7. Full Text Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
by Jostins, Luke and Ripke, Stephan and Weersma, Rinse K and Duerr, Richard H and McGovern, Dermot P and Hui, Ken Y and Lee, James C and Schumm, L. Philip and Sharma, Yashoda and Anderson, Carl A and Essers, Jonah and Mitrovic, Mitja and Ning, Kaida and Cleynen, Isabelle and Theatre, Emilie and Spain, Sarah L and Raychaudhuri, Soumya and Goyette, Philippe and Wei, Zhi and Abraham, Clara and Achkar, Jean-Paul and Ahmad, Tariq and Amininejad, Leila and Ananthakrishnan, Ashwin N and Andersen, Vibeke and Anews, Jane M and Baidoo, Leonard and Balschun, Tobias and Bampton, Peter A and Bitton, Alain and Boucher, Gabrielle and Brand, Stephan and Büning, Carsten and Cohain, Ariella and Cichon, Sven and D'Amato, Mauro and de Jong, Dirk and Devaney, Kathy L and Dubinsky, Marla and Edwards, Cathryn and Ellinghaus, David and Ferguson, Lynnette R and Franchimont, Denis and Fransen, Karin and Gearry, Richard and Georges, Michel and Gieger, Christian and Glas, Jürgen and Haritunians, Talin and Hart, Ailsa and Hawkey, Chris and Hedl, Matija and Hu, Xinli and Karlsen, Tom H and Kupcinskas, Limas and Kugathasan, Subra and Latiano, Anna and Laukens, Debby and Lawrance, Ian C and Lees, Charlie W and Louis, Edouard and Mahy, Gillian and Mansfield, John and Morgan, Angharad R and Mowat, Craig and Newman, William and Palmieri, Orazio and Ponsioen, Cyriel Y and Potocnik, Uros and Prescott, Natalie J and Regueiro, Miguel and Rotter, Jerome I and Russell, Richard K and Sanderson, Jeremy D and Sans, Miquel and Satsangi, Jack and Schreiber, Stefan and Simms, Lisa A and Sventoraityte, Jurgita and Targan, Stephan R and Taylor, Kent D and Tremelling, Mark and Verspaget, Hein W and de Vos, Martine and Wijmenga, Cisca and Wilson, David C and Winkelmann, Juliane and Xavier, Ramnik J and Zeissig, Sebastian and Zhang, Bin and Zhang, Clarence K and Zhao, Hongyu and Silverberg, Mark S and Annese, Vito and Hakonarson, Hakon and Brant, Steven R and Radford-Smith, Graham and Mathew, Christopher G and Rioux, John D and Schadt, Eric E and ... and Int IBD Genetics Consortium IIBDGC and International IBD Genetics Consortium (IIBDGC) and The International IBD Genetics Consortium (IIBDGC) and Region Örebro län and Örebro universitet and Institutionen för medicinska vetenskaper
Nature, ISSN 0028-0836, 2012, Volume 491, Issue 7422, pp. 119 - 124
Crohn's disease and ulcerative colitis, the two common forms of inflammatory bowel disease (IBD), affect over 2.5 million people of European ancestry, with... 
HYPER-IGE SYNDROME | RISK LOCI | NETWORK | NUMBER | METAANALYSIS | TUBERCULOSIS | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY | MUTATIONS | EXPRESSION | Crohn Disease - genetics | Humans | Inflammatory Bowel Diseases - immunology | Colitis, Ulcerative - genetics | Mycobacterium tuberculosis - immunology | Inflammatory Bowel Diseases - physiopathology | Colitis, Ulcerative - immunology | Host-Pathogen Interactions - immunology | Mycobacterium tuberculosis - pathogenicity | Haplotypes - genetics | Mycobacterium - pathogenicity | Mycobacterium Infections - genetics | Inflammatory Bowel Diseases - genetics | Crohn Disease - microbiology | Mycobacterium Infections - microbiology | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Reproducibility of Results | Mycobacterium - immunology | Crohn Disease - immunology | Genome, Human - genetics | Phenotype | Colitis, Ulcerative - microbiology | Host-Pathogen Interactions - genetics | Polymorphism, Single Nucleotide - genetics | Inflammatory Bowel Diseases - microbiology | Crohn Disease - physiopathology | Colitis, Ulcerative - physiopathology | Inflammatory bowel disease | Candidates | Tuberculosis | Architecture | Genetics | Genomes | Diabetes | Gene expression | Health risk assessment | Immune system | Index Medicus | Rheumatology and Autoimmunity | Basic Medicine | Medical Genetics | Medicinsk genetik | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Reumatologi och inflammation | Medicinska och farmaceutiska grundvetenskaper | Klinisk medicin
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