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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2016, Volume 113, Issue 42, p. 11901
  We report on the sequencing of 10,545 human genomes at 30x-40x coverage with an emphasis on quality metrics and novel variant and sequence discovery. We find... 
Pathogens | Genetics | Genomes
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 11/2015, Volume 112, Issue 45, pp. 14024 - 14024
Observations from human microbiome studies are often conflicting or inconclusive. Many factors likely contribute to these issues including small cohort sizes,... 
Journal Article
Nature Genetics, ISSN 1061-4036, 03/2018, Volume 50, Issue 3, pp. 333 - 337
Understanding the significance of genetic variants in the non-coding genome is emerging as the next challenge in human genomics. We used the power of 11,257... 
HUMAN-DISEASE | VARIANTS | DATABASE | MUTATION | GENETICS & HEREDITY | FRAMEWORK | CLINVAR PUBLIC ARCHIVE | MODEL | DOMAINS | FEATURES | Usage | Research | Nucleotide sequencing | Genetic variation | Biological diversity | DNA sequencing | Nucleotide sequence | Genomes | Regulatory sequences | Genetic diversity | Gene sequencing | Proteins | Genetic variance | Maps | Constraints | Archives & records | Population | Mutation | Gene mapping | Bioinformatics
Journal Article
RNA, ISSN 1355-8382, 01/2011, Volume 17, Issue 5, pp. 933 - 943
MicroRNAs (miRNAs) are small non-coding RNAs involved in fine-tuning of gene regulation. Antisense oligonucleotides (ONs) are promising tools as anti-miRNA... 
Journal Article
RNA, ISSN 1355-8382, 02/2008, Volume 14, Issue 2, pp. 336 - 346
MicroRNAs are small noncoding RNAs that regulate many cellular processes in a post-transcriptional mode. MicroRNA knockdown by antisense oligonucleotides is a... 
Journal Article
Blood Cells, Molecules and Diseases, ISSN 1079-9796, 2007, Volume 38, Issue 1, pp. 1 - 7
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2015, Volume 112, Issue 45, p. 14024
  Observations from human microbiome studies are often conflicting or inconclusive. Many factors likely contribute to these issues including small cohort... 
Polymerase chain reaction | Taxonomy | Genomics | Genomes | Deoxyribonucleic acid--DNA
Journal Article
Journal of Nucleic Acids, ISSN 2090-0201, 2011, Volume 2011, pp. 748632 - 17
Design of site-selective artificial ribonucleases (aRNases) is one of the most challenging tasks in RNA targeting. Here, we designed and studied... 
Physiological aspects | Ribonuclease | Research | Structure
Journal Article
Journal of RNA I and Gene Silencing, ISSN 1747-0854, 05/2007, Volume 3, Issue 1, p. 258
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 01/2004, Volume 32, Issue 13, pp. 3887 - 3887
Antisense oligonucleotide conjugates, bearing constructs with two imidazole residues, were synthesized using a precursor-based technique employing... 
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2007, Volume 48, Issue 37, pp. 6569 - 6572
Directed Michaelis–Arbuzov reactions of support-bound internucleotide -benzyl- or -methyl-phosphite triesters with -phenylazobenzylamine or... 
RNA | DNA | PHOSPHORAMIDITES | AZOBENZENE | CHEMISTRY, ORGANIC | SWITCH | PHOTOREGULATION | PHOSPHITES | PHOTOCONTROL
Journal Article
Nucleic Acids Symposium Series, ISSN 0261-3166, 09/2008, Volume 52, Issue 1, pp. 31 - 32
Abstract Serum-stabilized PNA-internalization peptides (Pip) conjugated to PNA complementary to the 705 aberrant β-globin splice site are able to correct... 
Luciferases, Firefly - biosynthesis | RNA Splicing | Animals | MicroRNAs - antagonists & inhibitors | Humans | MicroRNAs - metabolism | Mice | Peptide Nucleic Acids - chemistry | HeLa Cells | Muscular Dystrophy, Duchenne - genetics | beta-Globins - genetics | Life Sciences | Biochemistry, Molecular Biology
Journal Article
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