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Molecular Neurobiology, ISSN 0893-7648, 9/2018, Volume 55, Issue 9, pp. 7216 - 7228
Lipid metabolism, specifically fatty acid oxidation (FAO) mediated by carnitine palmitoyltransferase (CPT) 1A, has been described to be an important actor of... 
Fatty acid oxidation | Neurology | Neurosciences | CPT1A | Biomedicine | Ghrelin | Cortical neurons | Neurobiology | GABA | Cell Biology | MOUSE-BRAIN | GERBIL HIPPOCAMPUS | INCREASES FOOD-INTAKE | ALZHEIMERS-DISEASE | NEUROSCIENCES | ENERGY-BALANCE | BODY-WEIGHT | MESSENGER-RNA | THERAPEUTIC TARGET | SHUNT ENZYMES | HORMONE SECRETAGOGUE RECEPTOR | Oxidation-Reduction | gamma-Aminobutyric Acid - metabolism | Mice, Inbred C57BL | Cells, Cultured | Citric Acid Cycle - drug effects | Ghrelin - pharmacology | Cerebral Cortex - metabolism | Animals | Hypothalamus - metabolism | Metabolome - drug effects | Carnitine O-Palmitoyltransferase - metabolism | Citrates - metabolism | Gene Deletion | Neurons - metabolism | Cerebral Cortex - drug effects | Hypothalamus - drug effects | Ketoglutaric Acids - metabolism | Neurons - drug effects | Fatty Acids - metabolism | Physiological aspects | Enzymes | Oxidation-reduction reaction | Fatty acids | Carnitine | Brain | 4-Aminobutyrate transaminase | Transaminase | Cortex | Central nervous system | Oxygen consumption | Hypothalamus | Metabolism | Palmitoyltransferase | Ablation | Carnitine palmitoyltransferase | Citric acid | γ-Aminobutyric acid | Mitochondria | Enzymatic activity | Mice | Oxidation | Lipid metabolism | Hipotàlem | Cerebral cortex | Hormones peptídiques | Metabolisme dels lípids | Peptide hormones | Escorça cerebral | Àcids grassos
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2014, Volume 9, Issue 5, p. e97195
Lipid metabolism in the ventromedial hypothalamus (VMH) has emerged as a crucial pathway in the regulation of feeding and energy homeostasis. Carnitine... 
ENERGY-BALANCE | BODY-WEIGHT | MALONYL-COA | FOOD-INTAKE | MULTIDISCIPLINARY SCIENCES | FEEDING-BEHAVIOR | FATTY-ACID-METABOLISM | GENE-EXPRESSION | ARCUATE NUCLEI | ACETYL-COA CARBOXYLASE | GLUCOSE-PRODUCTION | Dependovirus - genetics | Carnitine O-Palmitoyltransferase - genetics | Hyperphagia - enzymology | Ventromedial Hypothalamic Nucleus - physiopathology | Male | RNA, Messenger - metabolism | Obesity - genetics | Hyperglycemia - genetics | Isoenzymes - metabolism | Carnitine O-Palmitoyltransferase - metabolism | Lipid Metabolism - genetics | Gene Expression | Isoenzymes - genetics | RNA, Messenger - genetics | Rats | Ventromedial Hypothalamic Nucleus - metabolism | Hyperphagia - metabolism | Appetite Regulation - genetics | Eating - genetics | Rats, Sprague-Dawley | Genetic Vectors - genetics | Hyperphagia - genetics | Animals | Insulin Resistance - genetics | Hyperglycemia - enzymology | Obesity - enzymology | Enzymes | Brain | Physiological aspects | Ceramides | GABA | Insulin resistance | Lipids | Glutamate | Hyperphagia | Carnitine | Body weight | Homeostasis | Intracellular signalling | Sphingolipids | Biochemistry | Phospholipids | Hormones | Food science | Hypothalamus | Glucose | Kinases | Proteins | Signal transduction | Mitochondria | Hyperglycemia | Hypothalamus (ventromedial) | Energy | Metabolites | Ghrelin | Rodents | Physiology | Oxidation | Lipid metabolism | Appetite | Nutrition | Hypoglycemia | Metabolism | Palmitoyltransferase | Insulin | Fatty acids | Carnitine palmitoyltransferase | Feeding | Energy balance | Glutamic acid transporter | Diabetes | Molecular biology | Transporter | Hipotàlem | Adipose tissues | Metabolisme dels glúcids | Rats as laboratory animals | Metabolisme dels lípids | Carbohydrate metabolism | Peptide hormones | Glucosa | Esfingolípids | Carnitine palmitoyltransferase I | Hormones peptídiques | Teixit adipós | Carnitina palmitoïl-transferasa 1 | Rates (Animals de laboratori)
Journal Article
Sensors & Actuators: B. Chemical, ISSN 0925-4005, 10/2016, Volume 234, pp. 633 - 640
[Display omitted] A pseudopeptidic compound comprising a central C2 symmetric bis(aminoamide) moiety derived from the amino acid serine and two pyrene groups... 
Fluorescence | Live cells | Pyrene | Acidic organelles | Pseudopeptides | pH sensor | ELECTROCHEMISTRY | CHEMISTRY, ANALYTICAL | BODIPY | INTRACELLULAR PH | NANOPARTICLES | LYSOSOMAL PH | PEPTIDOMIMETICS | INSTRUMENTS & INSTRUMENTATION | COEFFICIENT | METAL | PROBE | LIVING CELLS | Cellular | Pyrenes | Excimers | Emission | Sensors | Organelles
Journal Article
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, ISSN 0002-7863, 05/2019, Volume 141, Issue 19, pp. 7736 - 7742
Acid ceramidase (AC) hydrolyzes ceramides into sphingoid bases and fatty acids. The enzyme is overexpressed in several types of cancer and Alzheimer's disease,... 
PHARMACOLOGICAL CHAPERONES | DISEASE | INHIBITORS | CHEMISTRY, MULTIDISCIPLINARY | DEFICIENCY | ACTIVITY-BASED PROBES | TRANSPLANTATION | Index Medicus
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 06/2012, Volume 53, Issue 6, pp. 1134 - 1143
Journal Article
Journal Article
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 6/2012, Volume 133, Issue 2, pp. 447 - 458
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2011, Volume 286, Issue 32, pp. 28200 - 28209
Dacarbazine (DTIC) is the treatment of choice for metastatic melanoma, but its response in patients remains very poor. Ceramide has been shown to be a death... 
MALIGNANT GLIOMA-CELLS | INHIBITION | DAUNORUBICIN-INDUCED APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROSTATE-CANCER | INDUCED AUTOPHAGY | DEATH | INDUCED CYTOTOXICITY | SPHINGOLIPIDS | TUMOR-GROWTH | UP-REGULATION | Gene Expression Regulation, Enzymologic - drug effects | Acid Ceramidase - genetics | Humans | Melanoma - enzymology | Acid Ceramidas