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anesthesia. intensive care medicine. transfusions. cell therapy and gene therapy (20) 20
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surgery. transplantations, organ and tissue grafts. graft diseases (20) 20
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hypertension, pulmonary - metabolism (19) 19
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hygiene (13) 13
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neoplasm staging (13) 13
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pulmonology and respiratory tract (13) 13
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1. Full Text EIF2AK4 mutations cause pulmonary veno-occlusive disease, a recessive form of pulmonary hypertension
by Eyries, Mélanie and Montani, David and Girerd, Barbara and Perret, Claire and Leroy, Anne and Lonjou, Christine and Chelghoum, Nadjim and Coulet, Florence and Bonnet, Damien and Dorfmüller, Peter and Fadel, Elie and Sitbon, Olivier and Simonneau, Gérald and Tregouët, David-Alexandre and Humbert, Marc and Soubrier, Florent
Nature genetics, ISSN 1061-4036, 01/2014, Volume 46, Issue 1, pp. 65 - 69
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Pulmonary Veno-Occlusive Disease - physiopathology | Humans | Middle Aged | Protein-Serine-Threonine Kinases - genetics | Hypertension, Pulmonary - physiopathology | Male | Chromosome Mapping | Young Adult | Homozygote | Pulmonary Veno-Occlusive Disease - genetics | Pedigree | Adult | Female | Mutation | Protein-Serine-Threonine Kinases - metabolism | Causes of | Physiological aspects | Genetic aspects | Research | Gene mutations | Pulmonary hypertension | Studies | Genetic counseling | Genes | Tomography | Software | Genomes | Kinases | Experiments | Siblings | Index Medicus | Life Sciences | Biochemistry, Molecular Biology | Genomics
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2. Chronic thromboembolic pulmonary hypertension: Animal models
by Mercier, Olaf and Fadel, Elie
The European respiratory journal, ISSN 0903-1936, 05/2013, Volume 41, Issue 5, pp. 1200 - 1206
Chronic thromboembolic pulmonary hypertension | Remodelling | Pulmonary circulation | Right ventricular function | Life Sciences & Biomedicine | Respiratory System | Science & Technology | Thrombosis - physiopathology | Angiography | Ventricular Dysfunction, Right | Humans | Hypertension, Pulmonary - physiopathology | Rats | Animals | Swine | Dogs | Mice | Thromboembolism - physiopathology | Disease Models, Animal | Pulmonary Embolism - physiopathology
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3. Full Text Multimodal Imaging Mass Spectrometry to Identify Markers of Pulmonary Arterial Hypertension in Human Lung Tissue Using MALDI-ToF, ToF-SIMS, and Hybrid SIMS
by Van Nuffel, Sebastiaan and Quatredeniers, Marceau and Pirkl, Alexander and Zakel, Julia and Le Caer, Jean-Pierre and Elie, Nicolas and Vanbellingen, Quentin P and Dumas, Sébastien Joël and Nakhleh, Morad Kamel and Ghigna, Maria-Rosa and Fadel, Elie and Humbert, Marc and Chaurand, Pierre and Touboul, David and Cohen-Kaminsky, Sylvia and Brunelle, Alain
Analytical chemistry (Washington), ISSN 0003-2700, 09/2020, Volume 92, Issue 17, pp. 12079 - 12087
Physical Sciences | Chemistry | Chemistry, Analytical | Science & Technology | Hypertension | Spectroscopy | Data analysis | Lipid composition | Medical imaging | Ions | Mass spectroscopy | Lipids | Secondary ion mass spectrometry | Tissues | Arteries | Pulmonary hypertension | Pathology | Lungs | Ionization | Diagnostic software | Biomarkers | Diagnostic systems | Scientific imaging | Mass spectrometry | Index Medicus | Analytical chemistry | Chemical Sciences
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4. Full Text Nebivolol for Improving Endothelial Dysfunction, Pulmonary Vascular Remodeling, and Right Heart Function in Pulmonary Hypertension
by Perros, Frédéric, PhD and Ranchoux, Benoît, PhD and Izikki, Mohamed, PhD and Bentebbal, Sana, PhD and Happé, Chris, PhD and Antigny, Fabrice, PhD and Jourdon, Philippe, PhD and Dorfmüller, Peter, MD, PhD and Lecerf, Florence, MSc and Fadel, Elie, MD and Simonneau, Gerald, MD and Humbert, Marc, MD, PhD and Bogaard, Harm Jan, MD, PhD and Eddahibi, Saadia, PhD
Journal of the American College of Cardiology, ISSN 0735-1097, 2015, Volume 65, Issue 7, pp. 668 - 680
Cardiovascular | Internal Medicine | β-blocker | nebivolol | inflammation | endothelial dysfunction | pulmonary hypertension | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Heart | Sects | Pulmonary hypertension | Endothelium | Studies | Cell growth | Pulmonary arteries | Mortality | Smooth muscle | Veins & arteries | Index Medicus | Abridged Index Medicus | Life Sciences
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5. Full Text Pulmonary endarterectomy in the management of chronic thromboembolic pulmonary hypertension
by Jenkins, David and Madani, Michael and Fadel, Elie and D’Armini, Andrea Maria and Mayer, Eckhard
European respiratory review, ISSN 0905-9180, 03/2017, Volume 26, Issue 143, p. 160111
Life Sciences & Biomedicine | Respiratory System | Science & Technology | Endarterectomy - mortality | Hypertension, Pulmonary - mortality | Pulmonary Embolism - complications | Postoperative Complications - etiology | Endarterectomy - adverse effects | Hospital Mortality | Risk Assessment | Humans | Risk Factors | Hypertension, Pulmonary - surgery | Hypertension, Pulmonary - physiopathology | Treatment Outcome | Pulmonary Artery - physiopathology | Postoperative Complications - mortality | Pulmonary Artery - surgery | Patient Selection | Pulmonary Embolism - mortality | Time Factors | Hemodynamics | Pulmonary Embolism - surgery | Chronic Disease | Hypertension, Pulmonary - etiology | Pulmonary Embolism - physiopathology | Index Medicus
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6. Full Text Ectopic upregulation of membrane-bound IL6R drives vascular remodeling in pulmonary arterial hypertension
by Tamura, Yuichi and Phan, Carole and Tu, Ly and Le Hiress, Morane and Thuillet, Raphaël and Jutant, Etienne-Marie and Fadel, Elie and Savale, Laurent and Huertas, Alice and Humbert, Marc and Guignabert, Christophe
The Journal of clinical investigation, ISSN 0021-9738, 05/2018, Volume 128, Issue 5, pp. 1956 - 1970
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Familial Primary Pulmonary Hypertension - pathology | Up-Regulation | Vascular Remodeling | Muscle, Smooth, Vascular - metabolism | Humans | Myocytes, Smooth Muscle - pathology | Rats | Familial Primary Pulmonary Hypertension - genetics | Mice, Transgenic | Pulmonary Artery - physiopathology | Signal Transduction - genetics | Muscle, Smooth, Vascular - physiopathology | Familial Primary Pulmonary Hypertension - metabolism | Familial Primary Pulmonary Hypertension - physiopathology | Arterioles - pathology | Muscle, Smooth, Vascular - pathology | Pulmonary Artery - metabolism | Animals | Arterioles - metabolism | Arterioles - physiopathology | Cytokine Receptor gp130 - biosynthesis | Mice | Myocytes, Smooth Muscle - metabolism | Pulmonary Artery - pathology | Care and treatment | Cytokine receptors | Physiological aspects | Development and progression | Health aspects | Pulmonary artery | Pulmonary hypertension | Interleukin-6 | Cytochrome | Hypertension | Animal models | Cytokines | Arterioles | Pathogenesis | Pulmonary arteries | Smooth muscle | Cardiovascular disease | Interleukin 6 | Proteins | Signal transduction | Interleukin 6 receptors | Rodents | Medical prognosis | Hypoxia | Heart diseases | Growth factors | Glycoprotein gp130 | Veins & arteries | Index Medicus | Abridged Index Medicus | Life Sciences | Human health and pathology | Cellular Biology | Cardiology and cardiovascular system | Pulmonology and respiratory tract
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7. Full Text RV dysfunction after lung transplantation : a new prognostic marker or mainly a correlate of lung allograft function?
by Haddad, Francois and Fadel, Elie
JACC. Cardiovascular imaging, ISSN 1936-878X, 2014, Volume 7, Issue 11, pp. 1095 - 1097
Hypertension | Pulmonary survival | Echocardiography | Myocardial deformation imaging | Right ventricular function | Lung transplantation | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Lung Transplantation | Heart Ventricles - physiopathology | Humans | Female | Male | Ventricular Dysfunction, Right - physiopathology | Lung Diseases - surgery | Ventricular Function, Right | Index Medicus
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8. Full Text Telomere Maintenance Is a Critical Determinant in the Physiopathology of Pulmonary Hypertension
by Izikki, Mohamed, PhD and Hoang, Eric, BSc and Draskovic, Irena, PhD and Mercier, Olaf, MD, PhD and Lecerf, Florence, BSc and Lamrani, Lilia, MSc and Liu, Win-Yan, PhD and Guignabert, Christophe, PhD and Fadel, Elie, MD, PhD and Dorfmuller, Peter, MD, PhD and Humbert, Marc, MD, PhD and Londoño-Vallejo, Arturo, MD, PhD and Eddahibi, Saadia, PhD
Journal of the American College of Cardiology, ISSN 0735-1097, 2015, Volume 66, Issue 17, pp. 1942 - 1943
Cardiovascular | Internal Medicine | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Hypertension, Pulmonary - physiopathology | Telomere - physiology | Humans | Cell Proliferation - physiology | Pulmonary Artery - cytology | Pulmonary hypertension | Antigens | Cell growth | Disease | Pulmonary arteries | Rodents | Chromosomes | Telomerase | Cancer | Index Medicus | Abridged Index Medicus | Life Sciences
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9. Full Text Proinflammatory Signature of the Dysfunctional Endothelium in Pulmonary Hypertension Role of the Macrophage Migration Inhibitory Factor/CD74 Complex
by Le Hiress, M and Tu, L and Ricard, N and Phan, C and Thuillet, R and Fadel, E and Dorfmuller, P and Montani, D and de Man, F.S and Humbert, M and Huertas, A and Guignabert, C
American journal of respiratory and critical care medicine, ISSN 1073-449X, 2015, Volume 192, Issue 8, pp. 983 - 997
Macrophage migration inhibitory factor | CD74 signaling pathway | Endothelial dysfunction | Adhesion molecules | Pulmonary hypertension | Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Leukocytes, Mononuclear - metabolism | Up-Regulation | Humans | Macrophage Migration-Inhibitory Factors - immunology | Middle Aged | Macrophage Migration-Inhibitory Factors - metabolism | Male | Case-Control Studies | Familial Primary Pulmonary Hypertension - metabolism | Pulmonary Artery - metabolism | Familial Primary Pulmonary Hypertension - immunology | Leukocytes, Mononuclear - immunology | Antigens, Differentiation, B-Lymphocyte - immunology | Adult | Female | Histocompatibility Antigens Class II - metabolism | Disease Models, Animal | Endothelium, Vascular - immunology | Vascular Cell Adhesion Molecule-1 - immunology | Signal Transduction | Endothelial Cells - metabolism | Intercellular Adhesion Molecule-1 - immunology | Cells, Cultured | Endothelium, Vascular - physiopathology | Rats | E-Selectin - metabolism | E-Selectin - immunology | Inflammation | Endothelial Cells - immunology | Intercellular Adhesion Molecule-1 - metabolism | Animals | Histocompatibility Antigens Class II - immunology | Endothelium, Vascular - metabolism | Antigens, Differentiation, B-Lymphocyte - metabolism | In Vitro Techniques | Vascular Cell Adhesion Molecule-1 - metabolism | Pulmonary Artery - immunology | Index Medicus | Abridged Index Medicus | Life Sciences | Human health and pathology | Cellular Biology | Cardiology and cardiovascular system | Pulmonology and respiratory tract
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10. Full Text Dysregulated Renin-Angiotensin-Aldosterone System Contributes to Pulmonary Arterial Hypertension
by de Man, F.S and Tu, L and Handoko, M.L and Rain, S and Ruiter, G and Francois, C and Schalij, I and Dorfmuller, P and Simonneau, G and Fadel, E and Perros, F and Boonstra, A and Postmus, P.E and van der Velden, J and Vonk Noordegraaf, A and Humbert, M and Eddahibi, S and Guignabert, C
American journal of respiratory and critical care medicine, ISSN 1073-449X, 2012, Volume 186, Issue 8, pp. 780 - 789
Idiopathic pulmonary arterial hypertension | Renin angiotensin system | Smooth muscle cells | Monocrotaline | Endothelial cells | Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | Intensive care medicine | Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases | Medical sciences | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy | Pneumology | Up-Regulation | Humans | Middle Aged | Cells, Cultured | Losartan - pharmacology | Proportional Hazards Models | Hypertension, Pulmonary - physiopathology | Rats | Familial Primary Pulmonary Hypertension | Male | Angiotensin II Type 1 Receptor Blockers - pharmacology | Case-Control Studies | Disease Progression | Animals | Myocytes, Smooth Muscle | Receptor, Angiotensin, Type 1 - metabolism | Female | Renin-Angiotensin System - drug effects | Hypertension, Pulmonary - drug therapy | Endothelium, Vascular | Index Medicus | Abridged Index Medicus | Receptor, Angiotensin, Type 1 | endothelial cells | monocrotaline | Hypertension, Pulmonary | renin angiotensin system | idiopathic pulmonary arterial hypertension | smooth muscle cells | Angiotensin II Type 1 Receptor Blockers | Renin-Angiotensin System | Losartan
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11. Full Text Contractile Dysfunction of Left Ventricular Cardiomyocytes in Patients With Pulmonary Arterial Hypertension
by Manders, Emmy, MSc and Bogaard, Harm-Jan, MD, PhD and Handoko, M. Louis, MD, PhD and van de Veerdonk, Marielle C., MD and Keogh, Anne, MD and Westerhof, Nico, PhD and Stienen, Ger J.M., PhD and dos Remedios, Cristobal G., PhD, Dsc and Humbert, Marc, MD, PhD and Dorfmüller, Peter, MD, PhD and Fadel, Elie, MD, PhD and Guignabert, Christophe, PhD and van der Velden, Jolanda, PhD and Vonk-Noordegraaf, Anton, MD, PhD and de Man, Frances S., PhD and Ottenheijm, Coen A.C., PhD
Journal of the American College of Cardiology, ISSN 0735-1097, 2014, Volume 64, Issue 1, pp. 28 - 37
Cardiovascular | Internal Medicine | contractile protein phosphorylation | left ventricular dysfunction | pulmonary arterial hypertension | myocyte physiology | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Cardiology. Vascular system | Heart | Biological and medical sciences | Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases | Medical sciences | Pneumology | Humans | Middle Aged | Myocardial Contraction - physiology | Cells, Cultured | Hypertension, Pulmonary - physiopathology | Familial Primary Pulmonary Hypertension | Male | Ventricular Dysfunction, Left - physiopathology | Young Adult | Myocytes, Cardiac - pathology | Myocytes, Cardiac - physiology | Adolescent | Ventricular Dysfunction, Left - pathology | Adult | Female | Hypertension, Pulmonary - pathology | Transplantation of organs, tissues, etc | Complications and side effects | Sects | Care and treatment | Mortality | Pulmonary hypertension | Hypertension | Proteins | Phosphorylation | Heart attacks | Nuclear magnetic resonance--NMR | Pulmonary arteries | Biopsy | Rodents | Cardiomyocytes | Cardiology | Index Medicus | Abridged Index Medicus
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12. Full Text Platelet-derived Growth Factor Expression and Function in Idiopathic Pulmonary Arterial Hypertension
by Perros, Frederic and Montani, David and Dorfmuller, Peter and Durand-Gasselin, Ingrid and Tcherakian, Colas and Le Pavec, Jerome and Mazmanian, Michel and Fadel, Elie and Mussot, Sacha and Mercier, Olaf and Herve, Philippe and Emilie, Dominique and Eddahibi, Saadia and Simonneau, Gerald and Souza, Rogerio and Humbert, Marc
American journal of respiratory and critical care medicine, ISSN 1073-449X, 07/2008, Volume 178, Issue 1, pp. 81 - 88
Imatinib | Pulmonary arterial hypertension | Platelet-derived growth factor | Remodeling | Smooth muscle cells | Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Platelet | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy | Biological and medical sciences | Intensive care medicine | Blood coagulation. Blood cells | Molecular and cellular biology | Medical sciences | Phosphorylation | Muscle, Smooth, Vascular - metabolism | Apoptosis - drug effects | Proto-Oncogene Proteins c-sis | Cell Count | Humans | Hypertension, Pulmonary - metabolism | Platelet-Derived Growth Factor - pharmacology | Pyrimidines - pharmacology | RNA, Messenger - metabolism | Imatinib Mesylate | Piperazines - pharmacology | Cell Movement - drug effects | Muscle, Smooth, Vascular - pathology | Platelet-Derived Growth Factor - metabolism | Pulmonary Artery - metabolism | Receptors, Platelet-Derived Growth Factor - metabolism | Cell Proliferation - drug effects | Lung - metabolism | Protein Kinase Inhibitors - pharmacology | Benzamides | Hypertension, Pulmonary - pathology | Pulmonary Artery - pathology | Receptor, Platelet-Derived Growth Factor beta - metabolism | Index Medicus | Abridged Index Medicus
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