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index medicus (16) 16
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research (5) 5
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adipose-tissue (4) 4
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chrebp (4) 4
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hepatic steatosis (4) 4
lipids (4) 4
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biochemistry & molecular biology (3) 3
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insulin (3) 3
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protein-serine-threonine kinases - metabolism (3) 3
pyruvate-kinase gene (3) 3
steatosis (3) 3
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acetylation (2) 2
activated receptor-alpha (2) 2
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basic helix-loop-helix leucine zipper transcription factors - metabolism (2) 2
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Journal of Clinical Investigation, ISSN 0021-9738, 12/2010, Volume 120, Issue 12, pp. 4316 - 4331
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2012, Volume 122, Issue 6, pp. 2176 - 2194
Journal Article
Diabetes, ISSN 0012-1797, 08/2006, Volume 55, Issue 8, pp. 2159 - 2170
Liver-Specific Inhibition of ChREBP Improves Hepatic Steatosis and Insulin Resistance in ob/ob Mice Renaud Dentin 1 , Fadila Benhamed 1 , Isabelle Hainault 2 ,... 
ACC, acetyl-CoA carboxylase | Ad-GFP, GFP adenovirus | Ad-shChREBP, recombinant adenovirus expressing short hairpin RNA against ChREBP | ERK, extracellular signal-related kinase | ChREBP, carbohydrate responsive element-binding protein | DIABETES-MELLITUS | FATTY-ACID OXIDATION | DE-NOVO LIPOGENESIS | MALONYL-COA | DISEASE | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | CARBOHYDRATE | ELEMENT-BINDING PROTEIN | NONALCOHOLIC STEATOHEPATITIS | DEFICIENT MICE | RNA, Small Interfering - genetics | Nuclear Proteins - analysis | Insulin - physiology | RNA, Messenger - analysis | Male | Lipids - biosynthesis | Obesity - genetics | Adipose Tissue - metabolism | Transfection | Insulin Resistance - physiology | Muscle, Skeletal - chemistry | Fatty Acids, Nonesterified - blood | Nuclear Proteins - genetics | Glycogen - analysis | Dietary Carbohydrates - administration & dosage | Fatty Liver - genetics | Glucose Tolerance Test | Blood Glucose - analysis | Signal Transduction | Obesity - complications | Liver - metabolism | Fatty Liver - prevention & control | Transcription Factors - antagonists & inhibitors | Transcription Factors - genetics | Down-Regulation - genetics | Liver - chemistry | Animals | Nuclear Proteins - antagonists & inhibitors | Triglycerides - blood | Glucose - metabolism | Mice, Obese | Mice | Lipids - analysis | Leptin - deficiency | Fatty Liver - etiology | Prevention | Insulin resistance | Care and treatment | Research | Diabetes | Health aspects | Index Medicus | Abridged Index Medicus
Journal Article
Nature Medicine, ISSN 1078-8956, 07/2018, Volume 24, Issue 7, pp. 1070 - 1080
Journal Article
Clinics and Research in Hepatology and Gastroenterology, ISSN 2210-7401, 02/2018, Volume 42, Issue 1, pp. 3 - 5
The molecular mechanisms underlying fatty liver progression towards more severe syndromes are complex and only partially understood. Studies have recently... 
Lipotoxicity;NAFLD | SREBP-1c | De novo lipogenesis | NAFLD | HDAC3 | INSULIN-RESISTANCE | FATTY LIVER | MICE | Lipotoxicity | GASTROENTEROLOGY & HEPATOLOGY | TRANSCRIPTION FACTOR | HEPATIC STEATOSIS | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2005, Volume 115, Issue 10, pp. 2843 - 2854
Dietary polyunsaturated fatty acids (PUFAs) are potent inhibitors of hepatic glycolysis and lipogenesis. Recently, carbohydrate-responsive element-binding... 
RESPONSE ELEMENT | MEDICINE, RESEARCH & EXPERIMENTAL | POSTTRANSCRIPTIONAL REGULATION | COORDINATE SUPPRESSION | PENTOSE-PHOSPHATE PATHWAY | RAT HEPATOCYTES | MESSENGER-RNA | GLUCOSE-METABOLISM | NUTRITIONAL REGULATION | ELEMENT-BINDING PROTEIN | PYRUVATE-KINASE GENE | Gene Expression Regulation, Enzymologic - drug effects | Pentose Phosphate Pathway - drug effects | Pyruvate Kinase - biosynthesis | Multienzyme Complexes - metabolism | Male | Eicosapentaenoic Acid - administration & dosage | Gene Expression Regulation, Enzymologic - physiology | Glycolysis - drug effects | AMP-Activated Protein Kinases | Dietary Fats, Unsaturated - pharmacology | Fatty Acid Synthases - biosynthesis | Glycolysis - physiology | Eicosapentaenoic Acid - pharmacology | Fatty Acid Synthases - genetics | Lipogenesis - physiology | Protein-Serine-Threonine Kinases - metabolism | Pentose Phosphate Pathway - physiology | Cells, Cultured | Nuclear Proteins - metabolism | Docosahexaenoic Acids - administration & dosage | Down-Regulation - drug effects | Down-Regulation - physiology | Transcription Factors - metabolism | Docosahexaenoic Acids - pharmacology | Animals | Lipogenesis - drug effects | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Dietary Fats, Unsaturated - administration & dosage | Mice | Pyruvate Kinase - genetics | Hepatocytes - enzymology | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2004, Volume 279, Issue 19, pp. 20314 - 20326
Hepatic glucokinase (GK) catalyzes the phosphorylation of glucose to glucose 6-phosphate (G6P), a step which is essential for glucose metabolism in liver as... 
FATTY-ACID-SYNTHASE | GLUCOSE-HOMEOSTASIS | CARBOHYDRATE RESPONSE ELEMENT | RAT HEPATOCYTES | STEROL REGULATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ELEMENT-BINDING PROTEIN-1C | PYRUVATE-KINASE GENE | TRANSCRIPTION FACTOR | CARNITINE-PALMITOYLTRANSFERASE-I | TRANSGENIC MICE | Glucokinase - physiology | Liver - enzymology | Fatty Acid Synthases - metabolism | Immunoblotting | Hepatocytes - metabolism | RNA, Messenger - metabolism | DNA-Binding Proteins - metabolism | Cell Nucleus - metabolism | Glycogen - metabolism | Time Factors | CCAAT-Enhancer-Binding Proteins - physiology | Adenoviridae - genetics | Transcription, Genetic | Pentosephosphates - metabolism | RNA - metabolism | CCAAT-Enhancer-Binding Proteins - metabolism | DNA-Binding Proteins - physiology | Pyruvate Kinase - metabolism | Signal Transduction | Liver - metabolism | Mice, Inbred C57BL | Carbohydrate Metabolism | Cells, Cultured | Gene Expression Regulation | Lipid Metabolism | Mice, Transgenic | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Nuclear Proteins | Transcription Factors - metabolism | Blotting, Northern | Animals | Proteins - metabolism | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors | Glucose - metabolism | Mice | Kinetics | Sterol Regulatory Element Binding Protein 1 | Glucose-6-Phosphate - metabolism | Acetyl-CoA Carboxylase - metabolism | Microscopy, Fluorescence | RNA, Small Interfering - metabolism | Index Medicus
Journal Article
Journal Article
Gut, ISSN 0017-5749, 07/2016, Volume 65, Issue 7, pp. 1202 - 1214
Journal Article
PLOS ONE, ISSN 1932-6203, 07/2017, Volume 12, Issue 7, pp. e0181393 - e0181393
Journal Article