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Journal Article
Journal of immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 11/2008, Volume 181, Issue 9, pp. 6082 - 6091
In CD45 deficient animals there is a severe defect in thymocyte positive selection, resulting in an absence of mature T cells and the accumulation of... 
Cell Differentiation | Phosphatases | T cells | Kinases | Cell Activation | Thymus
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 135, Issue 2, pp. AB221 - AB221
  Methods To compare the relative efficacy of these two antibodies at inducing eosinophil cell death in peripheral eosinophils from patients with... 
Allergy and Immunology | Leucocytes | Apoptosis
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 02/2007, Volume 178, Issue 4, pp. 2056 - 2064
CD45-dependent dephosphorylation of the negative regulatory C-terminal tyrosine of the Src family kinase Lck, promotes efficient TCR signal transduction.... 
Journal Article
Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 4092 - 4092
Abstract Background: Systemic mastocytosis (SM) is a rare myeloproliferative neoplasm characterized by the accumulation of neoplastic mast cells (MC) in one or... 
Journal Article
Molecular Therapy, ISSN 1525-0016, 11/2012, Volume 20, Issue 11, pp. 2180 - 2189
The feasibility of allogeneic transplantation, without myeloablation or post-transplant immunosuppression, was tested using chemoselection of allogeneic... 
MEDICINE, RESEARCH & EXPERIMENTAL | NITROSOUREA RESISTANCE | BONE-MARROW-TRANSPLANTATION | RETROVIRAL TRANSDUCTION | MEDIATED TRANSFER | IN-VIVO SELECTION | LARGE-ANIMAL MODEL | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | HEMATOPOIETIC STEM-CELLS | GENETICS & HEREDITY | KINASE SUICIDE GENE | BETA-THALASSEMIA | DRUG-RESISTANCE GENE | Cell Proliferation | Tumor Suppressor Proteins - antagonists & inhibitors | DNA Modification Methylases - antagonists & inhibitors | Humans | DNA Repair Enzymes - genetics | Male | Green Fluorescent Proteins - genetics | Transplantation, Homologous | Flow Cytometry | Cell Shape | Tumor Suppressor Proteins - genetics | HEK293 Cells | Erythrocytes - pathology | Female | Ganciclovir - pharmacology | Lentivirus - genetics | DNA Repair Enzymes - antagonists & inhibitors | Animals, Newborn | Cell Survival - drug effects | Antiviral Agents - pharmacology | beta-Thalassemia - therapy | Transduction, Genetic | Thymidine Kinase - genetics | Cell Separation | Graft Rejection - prevention & control | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Viral Proteins - genetics | Mice, Transgenic | Carmustine - pharmacology | Graft Enhancement, Immunologic | DNA Modification Methylases - genetics | Animals | Green Fluorescent Proteins - biosynthesis | Mice | Graft Rejection - immunology | Hematopoietic Stem Cell Transplantation - methods | Original
Journal Article
The Journal of Immunology, ISSN 0022-1767, 10/2006, Volume 177, Issue 7, pp. 4870 - 4879
Journal Article
Immunologic Research, ISSN 0257-277X, 7/2009, Volume 44, Issue 1, pp. 112 - 126
Current approaches for hematopoietic stem cell (HSC) and organ transplantation are limited by donor and host-mediated immune responses to allo-antigens.... 
Major histocompatibility complex (MHC) | O 6 -methylguanine-DNA-methyltransferase (MGMT) | Internal Medicine | Human leukocyte antigen (HLA) | Medicine/Public Health, general | Lentivirus | Allergology | Busulfan (BU) | RNA interference (RNAi) | MGMT P140K -2A-GFP lentivirus vector (MAG) | Immunology | 1,3-bis(2-chloroethyl)-1-nitroso-urea (BCNU) | Medicine & Public Health | Benzylguanine (BG) | Short hairpin-type RNAi (shRNA) | MGMT | 2A-GFP lentivirus vector (MAG) | methylguanine- DNA-methyltransferase (MGMT) | UNRELATED DONOR | O-6-methylguanine-DNA-methyltransferase (MGMT) | CHEMOPROTECTION | TRANSDUCTION | IMMUNOLOGY | LARGE-ANIMAL MODEL | THERAPY | BONE-MARROW TRANSPLANTATION | MGMT(P140K)-2A-GFP lentivirus vector (MAG) | SELECTION | DRUG-RESISTANCE GENE | RETROVIRAL VECTOR | LYMPHOCYTES | Hematopoietic Stem Cells - drug effects | Gene Transfer Techniques | RNA, Small Interfering - genetics | DNA Modification Methylases - metabolism | Humans | Gene Silencing | Histocompatibility Antigens Class I - immunology | Histocompatibility Antigens Class I - genetics | Carmustine - pharmacology | Gene Knockdown Techniques | Hematopoietic Stem Cells - immunology | Animals | Transfection | Mice | Hematopoietic Stem Cell Transplantation - methods | Genetic Vectors | Immunohistochemistry | Leucocytes | Transplants & implants | Ribonucleic acid--RNA | Stem cells | Index Medicus | RNAi – RNA interference | MAG - MGMTP140K-2A-GFP lentivirus vector | MGMT - O6-methylguanine-DNA-methyltransferase | BU - Busulfan | BG - Benzylguanine | BCNU - 1,3-bis(2-chloroethyl1-nitrosourea) | MHC – Major Histocompability Complex | shRNA - short hairpin-type RNAi | HLA – Human Leukocyte Antigen
Journal Article
The Journal of Immunology, ISSN 0022-1767, 10/2005, Volume 175, Issue 8, pp. 4927 - 4934
Journal Article
Blood, ISSN 0006-4971, 11/2008, Volume 112, Issue 11, pp. 3478 - 3478
Abstract Transplantation of genetically engineered hematopoietic stem cells (HSC) holds promise for treatment of genetic and other disorders; however, several... 
Journal Article
Immunology, ISSN 0019-2805, 08/2007, Volume 121, Issue 4, pp. 545 - 554
Although it is clear that the CD45 tyrosine phosphatase is required for efficient T-cell activation and T-cell development, the factors that regulate CD45... 
Journal Article
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