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1. Full Text Endophthalmitis: what role does vitrectomy play?
by Rocha De Sousa, A and Mendonça, C and Alves‐Faria, P and Gouveia, P and Falcão, M and Falcão‐Reis, F
Acta Ophthalmologica, ISSN 1755-375X, 09/2017, Volume 95, Issue S259, p. n/a
Purpose To evaluate predictors of visual outcome in a series of patients treated for postoperative endophthalmitis (PE) and analyze the role of therapeutic... 
Endophthalmitis | Analysis | Eye | Statistical analysis | Antibiotics | Visual acuity | Diagnosis | Regression analysis | Patients | Significance | Acuity
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2. Full Text Retinal toxicity of intraocular silicone oil: a retrospective study
by Rocha de Sousa, A and Roca, A and Barbosa‐Breda, J and Falcão‐Reis, F
Acta Ophthalmologica, ISSN 1755-375X, 10/2016, Volume 94, Issue S256, p. n/a
Purpose To determine the relation between the use of silicone oil (SO) as an intraocular tamponade and the incidence of unexplained loss of visual acuity.... 
Silicones | Hypertension | Toxicity | Retina | Visual acuity | Patients | Incidence | Acuity | Tamponade | Oil | Vision | Surgery | Eye (anatomy) | Intraocular pressure
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3. Full Text Hypotrichosis with juvenile macular dystrophy
by Oliveira-Ferreira, Cláudia and Leuzinger-Dias, Mariana and Tavares-Ferreira, João and Silva, Sérgio Estrela and Brandão, Elisete and Falcão-Reis, F and Rocha-Sousa, Amândio
Ophthalmic Genetics, ISSN 1381-6810, 11/2019, pp. 1 - 4
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4. Full Text Microbiological Profile of Infectious Keratitis in a Portuguese Tertiary Centre
by Oliveira-Ferreira, Cláudia and Leuzinger-Dias, Mariana and Tavares-Ferreira, João and Torrão, Luís and Falcão-Reis, F
Journal of Ophthalmology, ISSN 2090-004X, 10/2019, Volume 2019, pp. 1 - 6
The microbiological profile of infectious keratitis has shown great differences across the world. Due to the continuous shifting trends in microbiological... 
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5. Full Text The “complete vitrectomy performed early” treatment philosophy
by Rocha De Sousa, A and Gouveia, P and Correia‐Pinto, J and Alves, P and Falcao‐Reis, F
Acta Ophthalmologica, ISSN 1755-375X, 10/2015, Volume 93, p. n/a
Purpose To compare the impact of early versus late complete vitrectomy in the management of acute postoperative endophthalmitis (PE). Methods Retrospective... 
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6. Full Text Strategic participation in competitive electricity markets: Internal versus sectorial data analysis
by Pinto, Tiago and Falcão-Reis, Francisco
International Journal of Electrical Power and Energy Systems, ISSN 0142-0615, 06/2019, Volume 108, pp. 432 - 444
Current approaches for risk management in energy market participation mostly refer to portfolio optimization for long-term planning, and stochastic approaches... 
Perfect competition | Strategic negotiations | Electricity markets | Multi-agent simulation | Sectorial data | Artificial neural network | Risk management | BEHAVIOR | NEGOTIATION | SIMULATION | ENGINEERING, ELECTRICAL & ELECTRONIC | RENEWABLE ENERGY | FRAMEWORK | OPTIMIZATION | GENERATION | Case studies | Investment analysis | Information management | Neural networks
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7. Full Text Concentration gradient of endogenous noradrenaline from periphery to centre in the rabbit cornea
by FIGUEIRA, L and MATOS, J and SERRAO, P and FALCAO‐REIS, F and MOURA, D
Acta Ophthalmologica, ISSN 1755-375X, 09/2012, Volume 90
Purpose The source of endogenous catecholamines that activate corneal adrenoceptors is largely unknown. Since the cornea is a densely innervated tissue we... 
Phenols | Noradrenaline
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8. Full Text Refixation of subluxated capsular tension ring-intraocular lens complex REPLY
by Monteiro, T and Domingues, M and Falcao-Reis, F
JOURNAL OF CATARACT AND REFRACTIVE SURGERY, ISSN 0886-3350, 07/2010, Volume 36, Issue 7, pp. 1242 - 1243
SURGERY | OPHTHALMOLOGY
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9. Full Text Concentration gradient of noradrenaline from the periphery to the centre of the cornea - A clue to its origin
by Figueira, Luis and Ferreira, Carla and Janeiro, Catarina and Serrao, Paula and Falcao-Reis, Fernando and Moura, Daniel
Experimental Eye Research, ISSN 0014-4835, 03/2018, Volume 168, pp. 107 - 114
We set out to demonstrate that the major source of corneal catecholamines is its neuronal release from intrinsic sympathetic nerves rather than circulating or... 
Human | Cornea | Sympathetic nerves | Rabbit | Neuronal topography | Noradrenaline origin | Concentration gradient | DOPAMINE-BETA-HYDROXYLASE | RELEASE | FAILURE | ADRENERGIC-NERVES | EYE | TRANSPORT | SYMPATHETIC INNERVATION | OPHTHALMOLOGY | AGE
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10. Full Text Corneal dendrites
by Queirós, Lara and Falcão-Reis, Fernando
New England Journal of Medicine, ISSN 0028-4793, 09/2012, Volume 367, Issue 10, pp. e14 - E14
A 34-year-old man presented to the emergency department with 3 days of photophobia, tearing, and the sensation of having a foreign body in his right eye. A... 
MEDICINE, GENERAL & INTERNAL | Cornea | Infections | Dendrites | Herpes viruses
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11. Full Text Regulation of corneal noradrenaline release and topography of sympathetic innervation: Functional implications for adrenergic mechanisms in the human cornea
by Figueira, Luis and Janeiro, Catarina and Ferreirinha, Fatima and Serrao, Paula and Perestrelo, Sara and Falcao-Reis, Fernando and Correia-de-Sa, Paulo and Moura, Daniel
Experimental Eye Research, ISSN 0014-4835, 09/2018, Volume 174, pp. 121 - 132
Having established a main neuronal origin for noradrenaline (NA) in the cornea, we set out to study the physiologic determinants of its release and to... 
Human | Cornea | Sympathetic nerves | Rabbit | Neuronal topography | Adrenergic mechanisms | Fractional rate of loss | Electrically-evoked overflow | Regulation of noradrenaline release | Alpha-2 adrenoceptors | NERVES | DOPAMINE-BETA-HYDROXYLASE | EPITHELIAL-CELLS | VIMENTIN | NEURONS | OPHTHALMOLOGY | MICE | RECEPTORS | EXPRESSION | WOUND REPAIR | Monoclonal antibodies | Phenols | Neurons | Laws, regulations and rules | Noradrenaline | Analysis
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12. Full Text Aflibercept in diabetic macular edema refractory to previous bevacizumab: outcomes and predictors of success
by Laiginhas, Rita and Laiginhas, Rita and Silva, Marta Inês and Silva, Marta Inês and Rosas, Vitor and Rosas, Vitor and Penas, Susana and Penas, Susana and Fernandes, Vitor Adriano and Fernandes, Vitor Adriano and Rocha-Sousa, Amândio and Rocha-Sousa, Amândio and Carneiro, Ângela and Carneiro, Ângela and Falcão-Reis, Fernando and Falcão-Reis, Fernando and Falcão, Manuel Sousa and Falcão, Manuel Sousa
Graefe's Archive for Clinical and Experimental Ophthalmology, ISSN 0721-832X, 1/2018, Volume 256, Issue 1, pp. 83 - 89
To evaluate functional and anatomical outcomes after aflibercept in patients with diabetic macular edema (DME) with poor response to bevacizumab.We... 
Refractory | Ophthalmology | Medicine & Public Health | Aflibercept | Diabetic macular edema | Bevacizumab | RANIBIZUMAB AND/OR BEVACIZUMAB | EYES | INTRAVITREAL RANIBIZUMAB | THERAPY | INJECTION | OPHTHALMOLOGY | THICKNESS | Dropsy | Edema | Diabetics | Eye | Diabetes mellitus | Diabetes | Variation | Acuity
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13. Full Text Choroidal thickness in multisystemic autoimmune diseases without ophthalmologic manifestations
by Ferreira, Carla S and Beato, João and Falcão, Manuel S and Brandão, Elisete and Falcão-Reis, Fernando and Carneiro, Ângela M
Retina, ISSN 0275-004X, 2017, Volume 37, Issue 3, pp. 529 - 535
Purpose: To evaluate choroidal morphology and thickness at the posterior pole of individuals affected by multisystemic autoimmune diseases and without known... 
Lupus | Choroidal thickness | Hydroxychloroquine | Autoimmune diseases | Rheumatoid arthritis | autoimmune diseases | RHEUMATOID-ARTHRITIS | DIABETIC-RETINOPATHY | INDOCYANINE GREEN | SYSTEMIC-LUPUS-ERYTHEMATOSUS | MANAGEMENT | OPTICAL COHERENCE TOMOGRAPHY | POSTERIOR POLE | CHOROIDOPATHY | lupus | rheumatoid arthritis | CATARACT-SURGERY | CENTRAL SEROUS CHORIORETINOPATHY | hydroxychloroquine | OPHTHALMOLOGY | choroidal thickness | Hydroxychloroquine - therapeutic use | Choroid - diagnostic imaging | Glucocorticoids - therapeutic use | Lupus Erythematosus, Systemic - complications | Cross-Sectional Studies | Tomography, Optical Coherence | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Autoimmune Diseases - complications | Organ Size | Male | Healthy Volunteers | Arthritis, Rheumatoid - complications | Arthritis, Rheumatoid - drug therapy | Lupus Erythematosus, Systemic - drug therapy | Adult | Female | Retrospective Studies | Choroid - pathology | Autoimmune Diseases - drug therapy | Antirheumatic Agents - therapeutic use
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14. Full Text Treatment of neovascular age‐related macular degeneration with anti‐VEGF agents: predictive factors of long‐term visual outcomes
by Pedrosa, A.C and Sousa, T and Pinheiro‐Costa, J and Beato, J and Falcão, M and Falcão‐Reis, F and Carneiro, Â
Acta Ophthalmologica, ISSN 1755-375X, 10/2016, Volume 94, Issue S256, p. n/a
Purpose To evaluate the predictive factors of long‐term visual outcomes in neovascular age‐related macular degeneration (nAMD) treated with anti‐VEGF agents.... 
Macular degeneration | Diabetic retinopathy | Care and treatment | Analysis | Physiological aspects | Neovascularization | Vascular endothelial growth factor | Multivariate analysis | Age | Visual aspects | Retina | Visual acuity | Epithelium | Patients | Hemorrhage | Age related diseases | Retinal pigment epithelium | Vascularization | Acuity | Atrophy | Fibrosis | Retinal degeneration | Diagnosis
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15. Full Text The charles bonnet syndrome in patients with neovascular age-related macular degeneration: Association with proton pump inhibitors
by Leandro, João Esteves and Beato, João and Pedrosa, Ana Catarina and Pinheiro-Costa, João and Falcão, Manuel and Falcão-Reis, Fernando and Carneiro, Ângela M
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 08/2017, Volume 58, Issue 10, pp. 4138 - 4142
PURPOSE. We investigate the prevalence of the Charles Bonnet syndrome (CBS) in patients with neovascular age-related macular degeneration (AMD) and analyze the... 
Oral proton pump inhibitors | Charles Bonnet syndrome | Low vision | Visual hallucinations | Neovascular age-related macular degeneration | neovascular age-related macular degeneration | low vision | COMPLEX VISUAL HALLUCINATIONS | POPULATION | oral proton pump inhibitors | BONNET,CHARLES SYNDROME | DISEASE | OPHTHALMOLOGY | visual hallucinations | PREVALENCE | Proton Pump Inhibitors - adverse effects | Prevalence | Wet Macular Degeneration - complications | Humans | Middle Aged | Risk Factors | Hallucinations - chemically induced | Logistic Models | Male | Hallucinations - epidemiology | Hallucinations - etiology | Syndrome | Portugal - epidemiology | Aged, 80 and over | Female | Aged
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16. Full Text Analysis of macular sensitivity using multifocal electroretinogram and microperimetry in central serous chorioretinopathy patients after half‐dose photodynamic therapy
by Rocha de Sousa, A and Rosinha, P and Rodrigues‐Araújo, J and Alves‐Faria, P and Costa, A and Falcão‐Reis, F and Penas, S
Acta Ophthalmologica, ISSN 1755-375X, 10/2016, Volume 94, Issue S256, p. n/a
Purpose To evaluate macular functional changes using multifocal electroretinography and microperimetry after half‐dose photodynamic therapy with verteporfin... 
Diabetic retinopathy | Care and treatment | Photochemotherapy | Analysis | Cancer | Electroretinography | Sensitivity | Sensitivity analysis | Photodynamic therapy | Correlation analysis | Retina | Charts | Event-related potentials | Eye (anatomy) | Patients | Structure-function relationships
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17. Full Text Macular hole angle as a surgery prognostic factor
by Rocha de Sousa, A and Silva, M.I and Morais, A.S and Falcao, M and Falcao‐Reis, F
Acta Ophthalmologica, ISSN 1755-375X, 10/2016, Volume 94, Issue S256, p. n/a
Purpose To analyze pre‐surgical macular hole (MH) angle measured by spectral domain optical coherence tomography (SD‐OCT) and its influence on anatomical and... 
Surgery | Analysis | Multivariate analysis | Statistical analysis | Independent variables | Visual observation | Retina | Visual acuity | Regression analysis | Acuity | Eye | Optical Coherence Tomography | Mathematical analysis | Dependent variables | Eye (anatomy)
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18. Full Text Switch to Aflibercept in the Treatment of Neovascular AMD: One-Year Results in Clinical Practice
by Pinheiro-Costa, João and Costa, José M and Beato, João N and Freitas-da-Costa, Paulo and Brandão, Elisete and Falcão, Manuel S and Falcão-Reis, Fernando and Carneiro, Ângela M
Ophthalmologica, ISSN 0030-3755, 06/2015, Volume 233, Issue 3-4, pp. 155 - 161
Purpose: To report the clinical outcomes of intravitreal aflibercept therapy in eyes with refractory and recurrent neovascular age-related macular degeneration... 
Original Paper | Wet age-related macular degeneration | Choroidal neovascularization | Switch | Aflibercept | Ranibizumab | Bevacizumab | TACHYPHYLAXIS | PHOTODYNAMIC THERAPY | MACULAR DEGENERATION | DISEASE | TRAP-EYE | OPHTHALMOLOGY | INTRAVITREAL BEVACIZUMAB | ANATOMICAL OUTCOMES | ANTI-VEGF THERAPY | ENDOTHELIAL GROWTH-FACTOR | Bevacizumab - therapeutic use | Receptors, Vascular Endothelial Growth Factor - therapeutic use | Follow-Up Studies | Intravitreal Injections | Tomography, Optical Coherence | Humans | Middle Aged | Recombinant Fusion Proteins - therapeutic use | Male | Treatment Outcome | Wet Macular Degeneration - physiopathology | Ranibizumab - therapeutic use | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Wet Macular Degeneration - diagnosis | Visual Acuity - drug effects | Wet Macular Degeneration - drug therapy | Aged, 80 and over | Angiogenesis Inhibitors - therapeutic use | Female | Aged | Retrospective Studies | Drug Substitution | Fluorescein Angiography
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19. Full Text ETB2 Receptor Subtype Stimulation Relaxes the Iris Sphincter Muscle
by Rocha-Sousa, A and Saraiva, J and Amaral, M and Alves-Faria, P and Falcao-Reis, F and Leite-Moreira, AF
PHYSIOLOGICAL RESEARCH, ISSN 0862-8408, 2009, Volume 58, Issue 6, pp. 835 - 842
Effects of ETB receptor stimulation and its subcellular pathways were evaluated in carbachol pre-contracted rabbit iris sphincter muscles (n=51). ETB... 
Sarafotoxin-s6c | ENDOTHELIN RECEPTOR | PHYSIOLOGY | QUANTITATIVE AUTORADIOGRAPHIC VISUALIZATION | MESSENGER-RNA EXPRESSION | SARAFOTOXIN S6C | SMALL-INTESTINE | Muscle fibers | Peptide hormones | CILIARY BODY | Iris | SMOOTH-MUSCLE | NITRIC-OXIDE | PROSTAGLANDIN RECEPTORS | ETB2 | PHOSPHOINOSITIDE TURNOVER | Electric Stimulation | Iris - metabolism | Endothelins - pharmacology | Nitric Oxide Synthase - antagonists & inhibitors | Male | Peptide Fragments - pharmacology | Dose-Response Relationship, Drug | Muscle, Smooth - drug effects | Receptor, Endothelin B - agonists | Piperidines - pharmacology | Iris - drug effects | Rabbits | Endothelin-1 - metabolism | Enzyme Inhibitors - pharmacology | Muscle, Smooth - metabolism | Indomethacin - pharmacology | Peptides - pharmacology | Nitroarginine - pharmacology | Carbachol - pharmacology | Animals | Prostaglandin-Endoperoxide Synthases - metabolism | Receptor, Endothelin A - metabolism | Nitric Oxide Synthase - metabolism | Receptor, Endothelin B - metabolism | Muscle Relaxation - drug effects | In Vitro Techniques | Nitric Oxide - metabolism | Oligopeptides - pharmacology | Prostaglandins - metabolism
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20. Full Text WAGNER syndrome: anatomic, functional and genetic characterization of a Portuguese family
by Araújo, Joana R and Araújo, Joana R and Tavares-Ferreira, João and Tavares-Ferreira, João and Estrela-Silva, Sérgio and Estrela-Silva, Sérgio and Rocha, Paulo and Rocha, Paulo and Brandão, Elisete and Brandão, Elisete and Faria, Pedro Alves and Faria, Pedro Alves and Falcão-Reis, Fernando and Falcão-Reis, Fernando and Rocha-Sousa, Amândio and Rocha-Sousa, Amândio
Graefe's Archive for Clinical and Experimental Ophthalmology, ISSN 0721-832X, 1/2018, Volume 256, Issue 1, pp. 163 - 171
To report the clinical (anatomic and functional) and genetic findings of Wagner Syndrome (WS) in a Portuguese family.Nine members of the family agreed to be... 
Hereditary vitreoretinopathy | Retinal detachment | VCAN | Medicine & Public Health | Ophthalmology | Wagner syndrome | Stickler syndrome | ABNORMALITIES | SITE MUTATION | EXON-2 | EROSIVE VITREORETINOPATHY | SPLICE VARIANTS | FEATURES | REGION | DISEASE | OPHTHALMOLOGY | STICKLER-SYNDROME | CSPG2 GENE | Eye | Medicine, Experimental | Medical research | Medical examination | Surgery | Visual field | Myopia | Electrophysiology | Retina | Electroretinograms | Atrophy | Photography | Color vision | Pedigree | Dystrophy | Deoxyribonucleic acid--DNA
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