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Journal Article
CELLS, ISSN 2073-4409, 04/2019, Volume 8, Issue 4, p. 353
The most common cystic fibrosis-causing mutation (F508del, present in similar to 85% of CF patients) leads to CFTR misfolding, which is recognized by the... 
arginine-framed tripeptides | diacidic code | PROTEIN | QUANTIFICATION | folding | CO-CHAPERONE | QUALITY-CONTROL | F508DEL-CFTR | CELL BIOLOGY | TRANSMEMBRANE CONDUCTANCE REGULATOR | RESCUE | endoplasmic reticulum quality control | DEGRADATION | interactome | CYSTIC-FIBROSIS | trafficking | CFTR | DELTA-F508 CFTR
Journal Article
Journal of Chemical Information and Modeling, ISSN 1549-9596, 06/2012, Volume 52, Issue 6, pp. 1686 - 1697
Journal Article
by Sieberts, Solveig K and Zhu, Fan and García-García, Javier and Stahl, Eli and Pratap, Abhishek and Pandey, Gaurav and Pappas, Dimitrios and Aguilar, Daniel and Anton, Bernat and Bonet, Jaume and Eksi, Ridvan and Fornés, Oriol and Guney, Emre and Li, Hongdong and Marín, Manuel Alejano and Panwar, Bharat and Planas-Iglesias, Joan and Poglayen, Daniel and Cui, Jing and Falcao, Ane O and Suver, Christine and Hoff, Bruce and Balagurusamy, Venkat S. K and Dillenberger, Donna and Neto, Elias Chaibub and Norman, Thea and Aittokallio, Tero and Ammad-Ud-Din, Muhammad and Azencott, Chloe-Agathe and Bellón, Víctor and Boeva, Valentina and Bunte, Kerstin and Chheda, Himanshu and Cheng, Lu and Corander, Jukka and Dumontier, Michel and Goldenberg, Anna and Gopalacharyulu, Peddinti and Hajiloo, Mohsen and Hiu, Daniel and Jaiswal, Alok and Kaski, Samuel and Khalfaoui, Beyrem and Khan, Suleiman Ali and Kramer, Eric R and Marttinen, Pekka and Mezlini, Aziz M and Molparia, Bhuvan and Pirinen, Matti and Saarela, Janna and Samwald, Matthias and Stoven, Véronique and Tang, Hao and Tang, Jing and Torkamani, Ali and Vert, Jean-Phillipe and Wang, Bo and Wang, Tao and Wennerberg, Krister and Wineinger, Nathan E and Xiao, Guanghua and Xie, Yang and Yeung, Rae and Zhan, Xiaowei and Zhao, Cheng and Greenberg, Jeff and Kremer, Joel and Michaud, Kaleb and Barton, Anne and Coenen, Marieke and Mariette, Xavier and Miceli, Corinne and Shadick, Nancy and Weinblatt, Michael and de Vries, Niek and Tak, Paul P and Gerlag, Danielle and Huizinga, Tom W. J and Kurreeman, Fina and Allaart, Cornelia F and Louis Bridges, S and Criswell, Lindsey and Moreland, Larry and Klareskog, Lars and Saevarsdottir, Saedis and Padyukov, Leonid and Gregersen, Peter K and Friend, Stephen and Plenge, Robert and Stolovitzky, Gustavo and Oliva, Baldo and Guan, Yuanfang and Mangravite, Lara M and Bridges, S. Louis and Calaza, Manuel and Elmarakeby, Haitham and Heath, Lenwood S and Long, Quan and Moore, Jonathan D and Opiyo, Stephen Obol and ... and Rheumatoid Arth Challenge and Members of the Rheumatoid Arthritis Challenge Consortium
Nature communications, ISSN 2041-1723, 2016, Volume 7, Issue 1, pp. 12460 - 12460
Journal Article
Journal Article
by Menden, Michael P and Wang, Dennis and Mason, Mike J and Szalai, Bence and Bulusu, Krishna C and Guan, Yuanfang and Yu, Thomas and Kang, Jaewoo and Jeon, Minji and Wolfinger, Russ and Nguyen, Tin and Zaslavskiy, Mikhail and Abante, Jordi and Abecassis, Barbara Schmitz and Aben, Nanne and Aghamirzaie, Delasa and Aittokallio, Tero and Akhtari, Farida S and Al-lazikani, Bissan and Alam, Tanvir and Allam, Amin and Allen, Chad and de Almeida, Mariana Pelicano and Altarawy, Doaa and Alves, Vinicius and Amadoz, Alicia and Anchang, Benedict and Antolin, Albert A and Ash, Jeremy R and Aznar, Victoria Romeo and Ba-alawi, Wail and Bagheri, Moeen and Bajic, Vladimir and Ball, Gordon and Ballester, Pedro J and Baptista, Delora and Bare, Christopher and Bateson, Mathilde and Bender, Andreas and Bertrand, Denis and Wijayawardena, Bhagya and Boroevich, Keith A and Bosdriesz, Evert and Bougouffa, Salim and Bounova, Gergana and Brouwer, Thomas and Bryant, Barbara and Calaza, Manuel and Calderone, Alberto and Calza, Stefano and Capuzzi, Stephen and Carbonell-Caballero, Jose and Carlin, Daniel and Carter, Hannah and Castagnoli, Luisa and Celebi, Remzi and Cesareni, Gianni and Chang, Hyeokyoon and Chen, Guocai and Chen, Haoran and Chen, Huiyuan and Cheng, Lijun and Chernomoretz, Ariel and Chicco, Davide and Cho, Kwang-Hyun and Cho, Sunghwan and Choi, Daeseon and Choi, Jaejoon and Choi, Kwanghun and Choi, Minsoo and Cock, Martine De and Coker, Elizabeth and Cortes-Ciriano, Isidro and Cserzö, Miklós and Cubuk, Cankut and Curtis, Christina and Daele, Dries Van and Dang, Cuong C and Dijkstra, Tjeerd and Dopazo, Joaquin and Draghici, Sorin and Drosou, Anastasios and Dumontier, Michel and Ehrhart, Friederike and Eid, Fatma-Elzahraa and ElHefnawi, Mahmoud and Elmarakeby, Haitham and van Engelen, Bo and Engin, Hatice Billur and de Esch, Iwan and Evelo, Chris and Falcao, Andre O and Farag, Sherif and Fernandez-Lozano, Carlos and Fisch, Kathleen and Flobak, Asmund and Fornari, Chiara and Foroushani, Amir B. K and Fotso, Donatien Chedom and Fourches, Denis and ... and AstraZeneca-Sanger Drug Combinatio and AstraZeneca-Sanger Drug Combination DREAM Consortium
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 2674 - 17
Journal Article
by Eduati, Federica and Mangravite, Lara M and Wang, Tao and Tang, Hao and Bare, J. Christopher and Huang, Ruili and Norman, Thea and Kellen, Mike and Menden, Michael P and Yang, Jichen and Zhan, Xiaowei and Zhong, Rui and Xiao, Guanghua and Xia, Menghang and Abdo, Nour and Kosyk, Oksana and Friend, Stephen and Dearry, Allen and Simeonov, Anton and Tice, Raymond R and Rusyn, Ivan and Wright, Fred A and Stolovitzky, Gustavo and Xie, Yang and Saez-Rodriguez, Julio and Aittokallio, Tero and Alaimo, Salvatore and Amadoz, Alicia and Ammad-ud-din, Muhammad and Azencott, Chloé-Agathe and Bacardit, Jaume and Barron, Pelham and Bernard, Elsa and Beyer, Andreas and Bin, Shao and van Bömmel, Alena and Borgwardt, Karsten and Brys, April M and Caffrey, Brian and Chang, Jeffrey and Chang, Jungsoo and Chheda, Himanshu and Christodoulou, Eleni G and Clément-Ziza, Mathieu and Cohen, Trevor and Cowherd, Marianne and Demeyer, Sofie and Dopazo, Joaquin and Elhard, Joel D and Falcao, Andre O and Ferro, Alfredo and Friedenberg, David A and Giugno, Rosalba and Gong, Yunguo and Gorospe, Jenni W and Granville, Courtney A and Grimm, Dominik and Heinig, Matthias and Hernansaiz, Rosa D and Hintsanen, Petteri and Hochreiter, Sepp and Huang, Liang-Chin and Huska, Matthew and Jaiswal, Alok and Jiao, Yunlong and Kaski, Samuel and Kaur, Ismeet and Ali Khan, Suleiman and Klambauer, Günter and Krasnogor, Natalio and Kuhn, Michael and Bartosz Kursa, Miron and Kutum, Rintu and Lazzarini, Nicola and Lee, Inhan and Leung, Michael K.K and Khong Lim, Weng and Liu, Charlie and Llinares López, Felipe and Mammana, Alessandro and Mayr, Andreas and Michoel, Tom and Mongiovì, Misael and Moore, Jonathan D and Mpindi, John-Patrick and Narasimhan, Ravi and Opiyo, Stephen O and Pandey, Gaurav and Peabody, Andrea L and Perner, Juliane and Poso, Antti and Pulvirenti, Alfredo and Rawlik, Konrad and Reinhardt, Susanne and Riffle, Carol G and Ruderfer, Douglas and Sander, Aaron J and Savage, Richard S and Scornet, Erwan and Sebastian-Leon, Patricia and ... and NIEHS-NCATS-UNC DREAM and The NIEHS-NCATS-UNC DREAM Toxicogenetics Collaboration
Nature Biotechnology, ISSN 1087-0156, 09/2015, Volume 33, Issue 9, pp. 933 - 940
The ability to computationally predict the effects of toxic compounds on humans could help address the deficiencies of current chemical safety testing. Here,... 
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Journal Article