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fixed constructions (49) 49
earth drilling (32) 32
earth drilling, e.g. deep drilling (32) 32
mining (32) 32
obtaining oil, gas, water, soluble or meltable materials or aslurry of minerals from wells (32) 32
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handling thin or filamentary material (6) 6
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lung cancer (5) 5
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measuring angles (5) 5
measuring areas (5) 5
measuring irregularities of surfaces or contours (5) 5
measuring length, thickness or similar lineardimensions (5) 5
mice (5) 5
mowing (5) 5
preventing derailing of rail vehicles (5) 5
rail vehicle suspensions, e.g. underframes, bogies orarrangements of wheel axles (5) 5
rail vehicles for use on tracks of different width (5) 5
resistance (5) 5
thermodynamics (5) 5
ubiquitin (5) 5
wheel guards, obstruction removers or the like for railvehicles (5) 5
cell death (4) 4
cell lung-cancer (4) 4
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energy & fuels (4) 4
engineering elements and units (4) 4
gene expression regulation, neoplastic (4) 4
general measures for producing and maintaining effectivefunctioning of machines or installations (4) 4
general tagging of cross-sectional technologies spanning over several sections of the ipc (4) 4
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geosciences, multidisciplinary (4) 4
kinases (4) 4
lung adenocarcinoma (4) 4
metastasis (4) 4
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phase change materials (4) 4
poly polymerase inhibitors - pharmacology (4) 4
protein kinase inhibitors - pharmacology (4) 4
signaling (4) 4
technical subjects covered by former uspc cross-reference art collections [xracs] and digests (4) 4
technologies or applications for mitigation or adaptation againstclimate change (4) 4
thermal insulation in general (4) 4
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Clinical Cancer Research, ISSN 1078-0432, 10/2017, Volume 23, Issue 20, pp. 6239 - 6254
Purpose: Drugs targeting DNA repair and cell-cycle checkpoints have emerged as promising therapies for small-cell lung cancer (SCLC). Among these, the WEE1... 
AZD1775 | PHASE-II TRIAL | MULTICENTER | MONOTHERAPY | CISPLATIN | ONCOLOGY | CHECKPOINT | ANTITUMOR-ACTIVITY | COMBINATION | CHEMOTHERAPY | TEMOZOLOMIDE | TOR Serine-Threonine Kinases - metabolism | Apoptosis - drug effects | Protein-Tyrosine Kinases - metabolism | Humans | Lung Neoplasms - metabolism | Apoptosis - genetics | Drug Resistance, Neoplasm | Lung Neoplasms - pathology | Extracellular Signal-Regulated MAP Kinases - metabolism | Cell Cycle Proteins - antagonists & inhibitors | Small Cell Lung Carcinoma - metabolism | Protein-Tyrosine Kinases - genetics | Ribosomal Protein S6 Kinases, 90-kDa - metabolism | Cell Cycle Proteins - genetics | DNA Damage - genetics | Female | Nuclear Proteins - genetics | Disease Models, Animal | Pyrazoles - pharmacology | DNA Damage - drug effects | Lung Neoplasms - genetics | Proto-Oncogene Proteins - metabolism | Gene Expression | Cell Cycle Proteins - metabolism | Nuclear Proteins - metabolism | Small Cell Lung Carcinoma - genetics | Pyrimidines - pharmacology | Receptor Protein-Tyrosine Kinases - metabolism | Xenograft Model Antitumor Assays | Small Cell Lung Carcinoma - pathology | Animals | Signal Transduction - drug effects | DNA Repair | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Mice | Protein Kinase Inhibitors - pharmacology | Protein-Tyrosine Kinases - antagonists & inhibitors | TOR protein | Drugs | Downstream effects | Lung cancer | DNA damage | Clinical trials | Activation | Drug delivery | DNA repair | Axl protein | Recruitment | Proteins | Inhibition | Repair | Deoxyribonucleic acid--DNA | Medical research | Small cell lung carcinoma | CHK1 protein | Extracellular signal-regulated kinase | Signaling | Protein arrays | Inhibitors | Experimental design | Cell lines | Cancer
Journal Article
Photonic Sensors, ISSN 1674-9251, 12/2017, Volume 7, Issue 4, pp. 350 - 356
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2016, Volume 11, Issue 4, p. e0152584
Small cell lung cancer (SCLC) is an aggressive malignancy with limited treatment options. We previously found that PARP is overexpressed in SCLC and that... 
BREAST-CANCER | POLY(ADP-RIBOSE) POLYMERASE | IN-VITRO | MULTIDISCIPLINARY SCIENCES | RESISTANCE | THERAPEUTIC TARGETS | DNA-REPAIR | TUMORS | CARCINOMA | DRUG-DRUG INTERACTIONS | PI3K INHIBITOR | Lung Neoplasms - drug therapy | AMP-Activated Protein Kinases - metabolism | TOR Serine-Threonine Kinases - metabolism | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Neoplasm Proteins - antagonists & inhibitors | Phosphatidylinositol 3-Kinases - metabolism | Neoplasm Proteins - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Small Cell Lung Carcinoma - drug therapy | Small Cell Lung Carcinoma - metabolism | TOR Serine-Threonine Kinases - antagonists & inhibitors | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Female | Indoles - pharmacology | Protein-Serine-Threonine Kinases - metabolism | Signal Transduction | AMP-Activated Protein Kinases - antagonists & inhibitors | Morpholines - pharmacology | Piperazines - pharmacology | Xenograft Model Antitumor Assays | Phthalazines - pharmacology | Poly(ADP-ribose) Polymerase Inhibitors - pharmacology | Poly(ADP-ribose) Polymerases - metabolism | Small Cell Lung Carcinoma - pathology | Animals | Mice, Nude | Aminopyridines - pharmacology | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Poly (ADP-Ribose) Polymerase-1 | Physiological aspects | Lung cancer, Small cell | Development and progression | Genetic aspects | Cellular signal transduction | Research | TOR protein | Drugs | Cell culture | Biotechnology | Animal models | Lung cancer | AKT protein | Oncology | Biology | Activation | Malignancy | Kinases | Cancer therapies | DNA repair | Ovarian cancer | Proteins | LKB1 protein | Signal transduction | Rodents | Bioindicators | Inhibition | Bioinformatics | Pharmaceutical sciences | Deoxyribonucleic acid--DNA | Medical research | Small cell lung carcinoma | Poly(ADP-ribose) polymerase | Breast cancer | Bioavailability | 1-Phosphatidylinositol 3-kinase | Studies | Signaling | Chemotherapy | Gene amplification | Protein arrays | Inhibitors | Biopsy | Cell lines | Biomarkers | In vivo methods and tests | ATP | Tumors | Cancer | Deoxyribonucleic acid | DNA
Journal Article
Energy Procedia, ISSN 1876-6102, 10/2018, Volume 152, pp. 186 - 191
Experiments were conducted to figure out the heat transfer mechanisms during the melting process of phase change materials (PCMs) in high-density polyethylene... 
natural convection | phase change material (PCM) | energy charging | heat transfer | ventilated panel | Phase change material (PCM) | Natural convection | Ventilated panel | Energy charging | Heat transfer
Journal Article
Molecular Cancer Research, ISSN 1541-7786, 01/2017, Volume 15, Issue 1, pp. 45 - 58
Journal Article
Energy Conversion and Management, ISSN 0196-8904, 01/2018, Volume 155, p. 230
Thermoelectric cooler (TEC) is attractive for cooling electronic devices because of its light, compact size, quiet and vibration free characteristics. However,... 
Electronic equipment | Gravitation | Vibration | Cooling | Electronic devices | Cooling rate | Feasibility studies | Flow rates | Air flow | Thermal resistance | Electronics industry | Test chambers | Air temperature | Heat pipes | Thermoelectric cooling | Flow velocity | Miniaturization | Energy management | Refrigerants | Heat transfer | Gravity
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 07/2016, Volume 22, Issue 14, pp. 3630 - 3642
Journal Article
Cell Death and Disease, ISSN 2041-4889, 05/2018, Volume 9, Issue 5, pp. 562 - 11
Therapy-induced expansion of cancer stem cells (CSCs) has been identified as one of the most critical factors contributing to therapeutic resistance, but the... 
Signal transduction | E2F protein | Transcription | Therapeutic applications | Stem cells | Prostate | Prostate cancer | Cancer
Journal Article
New Phytologist, ISSN 0028-646X, 02/2016, Volume 209, Issue 3, pp. 1028 - 1039
Journal Article