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TRENDS IN PHARMACOLOGICAL SCIENCES, ISSN 0165-6147, 05/2019, Volume 40, Issue 5, pp. 295 - 297
DNA damage repair (DDR) inhibition and immune checkpoint blockade (ICB) have each individually shown modest clinical activity in small cell lung cancer (SCLC).... 
CELL LUNG-CANCER | PHARMACOLOGY & PHARMACY | Medical colleges | Interferon | Biological response modifiers | Health aspects | Lung cancer
Journal Article
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 07/2019, Volume 25, Issue 22, pp. 6662 - 6670
Resistance to ALK tyrosine kinase inhibitors (TKIs) is often driven by mutations. Here we investigated utility of plasma genotyping for identifying resistance... 
Journal Article
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 09/2019, Volume 25, Issue 23, pp. 6958 - 6966
Although extensive-stage small cell lung cancer (SCLC) is highly responsive to first-line therapy, virtually all patients develop resistance with short... 
Journal Article
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2016, Volume 34, Issue 15_suppl, pp. 9072 - 9072
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2017, Volume 35, Issue 15_suppl, pp. 11580 - 11580
Journal Article
Journal of Thoracic Oncology, ISSN 1556-0864, 2019, Volume 14, Issue 5, pp. 835 - 843
Introduction: Lung cancer patients with tumors harboring actionable alterations can achieve very durable responses to first-line targeted therapy. However,... 
Never-smokers | Next-generation sequencing | Targeted therapy | Lung cancer | ONCOLOGY | RESPIRATORY SYSTEM
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 02/2018, Volume 378, Issue 8, pp. 731 - 739
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2015, Volume 33, Issue 15_suppl, pp. TPS2624 - TPS2624
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14_Supplement, pp. CT008 - CT008
Background: NTRK1, 2 and 3 gene fusions occur across a wide array of tumor types and can lead to constitutively-active TRKA, B, and C kinases. LOXO-101 is an... 
Journal Article
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, ISSN 1556-0864, 10/2018, Volume 13, Issue 10, pp. 1530 - 1538
Journal Article
Immunity, ISSN 1074-7613, 09/2015, Volume 43, Issue 3, pp. 579 - 590
Infiltration of regulatory T (Treg) cells into many tumor types correlates with poor patient prognoses. However, mechanisms of intratumoral Treg cell function... 
LUNG-CANCER | ADVANCED MELANOMA | IMMUNOTHERAPY | AUTOIMMUNITY | LONG-TERM SURVIVAL | MICE | INFECTION | DIFFERENTIATION | IMMUNOLOGY | EXPRESSION | MOUSE MODELS | Forkhead Transcription Factors - immunology | Immunohistochemistry | Neoplasms - metabolism | T-Lymphocytes, Regulatory - metabolism | Cell Proliferation | Dendritic Cells - immunology | Lung Neoplasms - metabolism | Lymphocyte Depletion | T-Lymphocytes, Regulatory - immunology | Lymphocyte Activation - immunology | Adenocarcinoma - metabolism | Flow Cytometry | Neoplasms - genetics | T-Lymphocytes - metabolism | Forkhead Transcription Factors - metabolism | Lymphocytes, Tumor-Infiltrating - metabolism | Adenocarcinoma - genetics | Dendritic Cells - metabolism | Lung Neoplasms - genetics | Adenocarcinoma - immunology | Cells, Cultured | Mice, Transgenic | Forkhead Transcription Factors - genetics | Microscopy, Confocal | Lung Neoplasms - immunology | Animals | Neoplasms - immunology | Luminescent Proteins - genetics | T-Lymphocytes - immunology | Luminescent Proteins - metabolism | Lymphocytes, Tumor-Infiltrating - immunology | Dendritic cells | Lung cancer | Analysis | Genetically modified organisms | Genetic engineering | T cells | Tumors | Medical research | Flow cytometry | Scholarships & fellowships | Lymphocytes | Rodents | Immunotherapy | Mortality | Immune system
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14_Supplement, pp. CT007 - CT007
Background: Entrectinib is a potent oral inhibitor of the tyrosine kinases TrkA, TrkB, TrkC (encoded by the genes NTRK1, NTRK2, NTRK3, respectively), ROS1, and... 
Journal Article
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