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1. Full Text Blood Glucose Variability
by Farkouh, Michael E., MD, MSc
JACC: Cardiovascular Interventions, ISSN 1936-8798, 2015, Volume 8, Issue 6, pp. 812 - 813
Cardiovascular
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2. Full Text A COGENT Argument for Gastrointestinal Protection With Low-Dose Aspirin
by Farkouh, Michael E., MD, MSc
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2016, Volume 67, Issue 14, pp. 1672 - 1673
  (4) compared the relative safety of high- versus low-dose aspirin after PCI in ST-segment elevation myocardial infarction from the HORIZONS (Harmonizing... 
Cardiovascular | Internal Medicine | coronary artery disease | clinical outcomes | clinical trials | bleeding | PROTON PUMP INHIBITORS | CARDIAC & CARDIOVASCULAR SYSTEMS | Omeprazole - therapeutic use | Humans | Platelet Aggregation Inhibitors - administration & dosage | Female | Male | Proton Pump Inhibitors - therapeutic use | Ticlopidine - analogs & derivatives | Aspirin - administration & dosage | Confidence intervals | Anticoagulants | Aspirin | Heart attacks | Antidepressants | Cardiovascular disease | Acute coronary syndromes | Cardiology | Hemorrhage
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3. Full Text Primary Prevention of Atherosclerotic Cardiovascular Disease
by Farkouh, Michael E., MD, MSc
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2014, Volume 64, Issue 10, pp. 969 - 970
  Even more disconcerting is that only 40% of family physicians, internists, and cardiologists used the assessment tool when assessing the prognosis of... 
Cardiovascular | Internal Medicine | Cardiovascular diseases | Mens health | Womens health | Physicians | Cardiovascular disease | Blood pressure | Diabetes | Health risk assessment | Patients | Cholesterol | Statins | Age | Risk factors
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4. Full Text The Reply
by Gandhi, Sumeet, MD and Abdel-Qadir, Husam, MD and Mosleh, Wassim, (Hon) BSc and Farkouh, Michael E., MD, MSc
American Journal of Medicine, The, ISSN 0002-9343, 2015, Volume 128, Issue 7, pp. e19 - e19
Internal Medicine
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5. Full Text Non-steroidal anti-inflammatory drugs and cardiovascular risk: At crossroads
by Farkouh, Michael E., MD, MSc, FRCPC, FACC, FAHA
Trends in Cardiovascular Medicine, ISSN 1050-1738, 2015, Volume 25, Issue 8, pp. 736 - 737
  In our large meta-analysis of over 300,000 patients, the Coxib and traditional NSAID Trialists' (CNT) Collaboration, naproxen has been associated with... 
Cardiovascular | GASTROINTESTINAL TOXICITY | RHEUMATOID-ARTHRITIS | IBUPROFEN | CARDIAC & CARDIOVASCULAR SYSTEMS | LUMIRACOXIB | ACUTE MYOCARDIAL-INFARCTION | ROFECOXIB | NAPROXEN | RANDOMIZED CONTROLLED-TRIAL | OSTEOARTHRITIS | INHIBITORS | Cardiovascular Diseases - etiology | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Humans | Cyclooxygenase 2 - metabolism | Female | Male | Cyclooxygenase 1 - metabolism | Nonsteroidal anti-inflammatory drugs | Cardiovascular diseases | Drug therapy | Risk factors | Aspirin | Heart attacks | Mortality | Clinical trials | Arthritis | Thrombosis | Studies | Side effects | Hypotheses | Blood platelets | Blood pressure | Health risk assessment | Drug dosages
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6. Full Text The PROSPECT of Changing Our Approach to Acute Coronary Syndromes
by Farkouh, Michael E., MD, MSc and Mathew, Verghese, MD
JACC: Cardiovascular Imaging, ISSN 1936-878X, 2012, Volume 5, Issue 3, pp. S73 - S75
Cardiovascular | atherosclerosis | lesion characterization | acute coronary syndrome | MORTALITY | HEART-DISEASE | CARDIAC & CARDIOVASCULAR SYSTEMS | CHRONIC KIDNEY-DISEASE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PROGRESSION | Plaque, Atherosclerotic - diagnosis | Coronary Artery Disease - diagnosis | Diabetes Mellitus - epidemiology | Humans | Kidney Diseases - epidemiology | Acute Coronary Syndrome - diagnosis | Female | Male | Metabolic Syndrome - epidemiology | Coronary Stenosis - diagnosis
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7. Full Text The Reply
by Aneja, Ashish, MD and Tang, W.H. Wilson, MD and Farkouh, Michael E., MD, MSc
American Journal of Medicine, The, ISSN 0002-9343, 2009, Volume 122, Issue 3, pp. e15 - e15
Internal Medicine
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8. Full Text A Polypill Strategy to Improve Adherence
by Castellano, José M., MD, PhD and Sanz, Ginés, MD, PhD and Peñalvo, José L., PhD and Bansilal, Sameer, MD, MS and Fernández-Ortiz, Antonio, MD, PhD and Alvarez, Luz, BSc and Guzmán, Luis, MD and Linares, Juan Carlos, MD and García, Fernando, MD, PhD and D’Aniello, Fabiana, PhD and Arnáiz, Joan Albert, MD, PhD and Varea, Sara, BSc and Martínez, Felipe, MD and Lorenzatti, Alberto, MD and Imaz, Iñaki, MD, PhD and Sánchez-Gómez, Luis M., MD, MSc and Roncaglioni, Maria Carla, Biol Sci Dr and Baviera, Marta, PharmD and Smith, Sidney C., MD and Taubert, Kathryn, PhD and Pocock, Stuart, PhD and Brotons, Carlos, MD, PhD and Farkouh, Michael E., MD, MSc and Fuster, Valentin, MD, PhD
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2014, Volume 64, Issue 20, pp. 2071 - 2082
Abstract Background Adherence to evidence-based cardiovascular (CV) medications after an acute myocardial infarction (MI) is low after the first 6 months. The... 
Cardiovascular | Internal Medicine | polypill | adherence | secondary prevention | Adherence | Secondary prevention | Polypill | Sects | Patient compliance | Analysis | Cardiac patients | Studies | Confidence intervals | Disease prevention | Heart attacks | Economic indicators | Mortality | Cardiovascular disease | Drug therapy | Drug dosages | Patients | Statins
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9. Full Text Cardiovascular and cerebrovascular events among patients receiving omalizumab: Results from EXCELS, a prospective cohort study of moderate-to-severe asthma
by Iribarren, Carlos, MD, MPH, PhD and Rahmaoui, Abdelkader, MD and Long, Aidan A., MD and Szefler, Stanley J., MD and Bradley, Mary S., MS and Carrigan, Gillis, PhD, MSc and Eisner, Mark D., MD, MPH and Chen, Hubert, MD, MPH and Omachi, Theodore A., MD, MBA and Farkouh, Michael E., MD, MSc and Rothman, Kenneth J., DrPH
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 139, Issue 5, pp. 1489 - 1495.e5
Abstract Background EXCELS was a postmarketing commitment to the US Food and Drug Administration to assess long-term safety of omalizumab in an observational... 
Allergy and Immunology | arterial thromboembolic event | safety | serious adverse event | Adverse event | clinical trials | omalizumab | moderate to severe asthma | EXHALED BREATH CONDENSATE | GLUCOCORTICOIDS | RISK | SEVERE ALLERGIC-ASTHMA | IMMUNOLOGY | ADULT-ONSET ASTHMA | ALLERGY | ANTIIMMUNOGLOBULIN-E THERAPY | SEVERE PERSISTENT ASTHMA | ACUTE MYOCARDIAL-INFARCTION | CORONARY-HEART-DISEASE | ANTI-IGE ANTIBODY | Anti-Asthmatic Agents - adverse effects | Prospective Studies | Omalizumab - adverse effects | Anti-Asthmatic Agents - therapeutic use | Humans | Middle Aged | Male | Asthma - drug therapy | Incidence | Cardiovascular Diseases - epidemiology | Product Surveillance, Postmarketing | Adult | Female | Omalizumab - therapeutic use | Cerebrovascular Disorders - epidemiology | Asthma - epidemiology | Health maintenance organizations | Pharmaceutical industry | Asthma in children | Stroke (Disease) | Thromboembolism | Analysis | Asthma | Myocardial infarction | Heart | Corticoids | C-reactive protein | Glucocorticoids | Adjudication | Cardiovascular disease | Risk factors | Cerebrovascular system | Motivation | Condensates | Flutter | Chronic obstructive pulmonary disease | Diagnosis | Cross sections | Emergency medical services | Cerebral infarction | Corticosteroids | Mortality | Assessments | Patients | Thrombosis | Quality of life | Side effects | Rheumatoid arthritis | Arteriosclerosis | Monoclonal antibodies | Death | Skin | Cardiovascular diseases | Circulation | Health care | Intervention | Transient ischemic attack | Identification methods | Congenital defects | Medical services | Clinical trials | Immunoglobulin E | Population studies | Arthritis | Malignancy | Angina | Congestive heart failure | Hemorrhage | Risk assessment | Safety engineering | Atherosclerosis | Patient safety | Safety | Drug therapy | Age | Cardiovascular system | Hypertension | Stroke | Statistical analysis | Complications | Hypersensitivity | Diabetes mellitus | Coronary artery disease | Ventricle | Respiration | Pharmaceuticals
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10. Full Text Targeting Preschool Children to Promote Cardiovascular Health: Cluster Randomized Trial
by Céspedes, Jaime, MD and Briceño, German, MD, MSc and Farkouh, Michael E., MD, MSc and Vedanthan, Rajesh, MD, MPH and Baxter, Jorge, MA and Leal, Martha, MD, MSc and Boffetta, Paolo, MD, PhD and Woodward, Mark, MSc and Hunn, Marilyn and Dennis, Rodolfo, MD, MSc and Fuster, Valentin, MD, PhD
American Journal of Medicine, The, ISSN 0002-9343, 2013, Volume 126, Issue 1, pp. 27 - 35.e3
Abstract Background School programs can be effective in modifying knowledge, attitudes, and habits relevant to long-term risk of chronic diseases associated... 
Internal Medicine | Global health | Noncommunicable disease (NCD) | Preschool children | Health education | Cardiovascular disease (CVD) | RISK-FACTORS | ADULTHOOD | PREVENTION | CHILDHOOD | MEDICINE, GENERAL & INTERNAL | VEGETABLE CONSUMPTION | COORDINATED APPROACH | OBESITY | FRUIT | OVERWEIGHT | PHYSICAL-ACTIVITY | Body Mass Index | Colombia | Life Style | Follow-Up Studies | Cardiovascular Diseases - prevention & control | Humans | Child, Preschool | Feeding Behavior | Male | Health Knowledge, Attitudes, Practice | Health Promotion | Diet | Adult | Female | Nutritional Status | Prevention | Educational programs | Health attitudes | Research | Management | Cardiovascular diseases | Health aspects | Risk factors | Life style
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11. Full Text Diabetic Cardiomyopathy: Insights into Pathogenesis, Diagnostic Challenges, and Therapeutic Options
by Aneja, Ashish, MD and Tang, W.H. Wilson, MD and Bansilal, Sameer, MD and Garcia, Mario J., MD and Farkouh, Michael E., MD, MSc
American Journal of Medicine, The, ISSN 0002-9343, 2008, Volume 121, Issue 9, pp. 748 - 757
Abstract Diabetic cardiomyopathy is the presence of myocardial dysfunction in the absence of coronary artery disease and hypertension. Hyperglycemia seems to... 
Internal Medicine | Heart Failure | Diastolic dysfunction | Treatment | Pathophysiology | Diabetes Mellitus | heart failure | treatment | PROTEIN-KINASE-C | ENDOTHELIUM-DEPENDENT RELAXATION | diabetes mellitus | ANGIOTENSIN-II | ALDOSTERONE RECEPTOR ANTAGONISTS | CARDIOVASCULAR HEALTH | MEDICINE, GENERAL & INTERNAL | CONVERTING ENZYME-INHIBITION | VENTRICULAR DIASTOLIC DYSFUNCTION | INSULIN-RESISTANCE | pathophysiology | diastolic dysfunction | CONGESTIVE-HEART-FAILURE | DOPPLER-ECHOCARDIOGRAPHY | Heart Failure, Diastolic - diagnosis | Echocardiography | Diabetes Complications - physiopathology | Heart Failure, Diastolic - drug therapy | Humans | Risk Factors | Ventricular Dysfunction, Left - etiology | Diabetes Complications - drug therapy | Myocardium - pathology | Renin-Angiotensin System - physiology | Ventricular Dysfunction, Left - diagnosis | Diabetes Complications - diagnosis | Necrosis - pathology | Diabetes Complications - etiology | Ventricular Dysfunction, Left - physiopathology | Fatty Acids, Nonesterified - metabolism | Heart Failure, Diastolic - physiopathology | Microcirculation - pathology | Ventricular Dysfunction, Left - drug therapy | Heart Failure, Diastolic - etiology | Myocardium - metabolism | Copper - metabolism | Apoptosis - physiology | Fibrosis - pathology
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12. Full Text Risk Factor Control for Coronary Artery Disease Secondary Prevention in Large Randomized Trials
by Farkouh, Michael E., MD, MSc and Boden, William E., MD and Bittner, Vera, MD, MSPH and Muratov, Victoria, MD, MPH and Hartigan, Pamela, PhD and Ogdie, May, MPH and Bertolet, Marnie, PhD and Mathewkutty, Shiny, MD and Teo, Koon, MBBch, PhD and Maron, David J., MD and Sethi, Sanjum S., MD and Domanski, Michael, MD and Frye, Robert L., MD and Fuster, Valentin, MD, PhD
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2013, Volume 61, Issue 15, pp. 1607 - 1615
Objectives This study evaluated data from 3 federally funded trials that focused on optimal medical therapy to determine if formalized attempts at risk factor... 
Cardiovascular | Internal Medicine | risk factor | clinical trials | secondary prevention | MORTALITY | DESIGN | CARDIAC & CARDIOVASCULAR SYSTEMS | POLYPILL | ADULTS | OPTIMAL MEDICAL THERAPY | ADHERENCE | STROKE | IMPACT | OUTCOMES UTILIZING REVASCULARIZATION | CARDIOVASCULAR-DISEASE | Glycated Hemoglobin A - analysis | Humans | Middle Aged | Male | Secondary Prevention - methods | Coronary Artery Disease - blood | Diabetes Mellitus, Type 2 - epidemiology | Diabetes Mellitus, Type 2 - therapy | Cholesterol, LDL - blood | Female | Hypoglycemic Agents - therapeutic use | Effect Modifier, Epidemiologic | Coronary Artery Bypass - methods | Risk Reduction Behavior | Comorbidity | Angioplasty, Balloon, Coronary - methods | Risk Factors | Coronary Artery Disease - prevention & control | Cardiovascular Agents - therapeutic use | Diabetes Mellitus, Type 2 - blood | Outcome and Process Assessment (Health Care) | Coronary Artery Disease - therapy | Monitoring, Physiologic - methods | Aged | Coronary Artery Disease - epidemiology | Coronary Artery Disease - psychology | Practice Guidelines as Topic | Smoking Cessation | Sects | Diabetics | Medical colleges | Low density lipoproteins | Clinical trials | Hemoglobin | Diabetes | Coronary heart disease | Hospitals, Veterans | Cholesterol | Infection control | Medical research | Heart attacks | Drug therapy | Cardiology | Coronary vessels
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13. Full Text Promotion of Cardiovascular Health in Preschool Children: 36-Month Cohort Follow-up
by Céspedes, Jaime, MD and Briceño, German, MD, MSc and Farkouh, Michael E., MD, MSc and Vedanthan, Rajesh, MD, MPH and Baxter, Jorge, MA and Leal, Martha, MD, MSc and Boffetta, Paolo, MD, MPH and Hunn, Marilyn and Dennis, Rodolfo, MD, MSc and Fuster, Valentin, MD, PhD
American Journal of Medicine, The, ISSN 0002-9343, 2013, Volume 126, Issue 12, pp. 1122 - 1126
Abstract Background Educational interventions in preschool children could improve dietary behavior and physical activity, and prevent unhealthy body weights in... 
Internal Medicine | Global health | Noncommunicable disease (NCD) | Preschool children | Health education | Cardiovascular disease (CVD) | SCHOOL-BASED INTERVENTION | RISK-FACTORS | COUNTRIES | ADULTHOOD | PREVENTION | TRIAL | MEDICINE, GENERAL & INTERNAL | IMPACT | DISEASE | PHYSICAL-ACTIVITY | CHILDHOOD OBESITY | Health Education - methods | Health Promotion - methods | Cardiovascular Diseases - prevention & control | Humans | Child, Preschool | Adult | Feeding Behavior | Female | Male | Health Knowledge, Attitudes, Practice | Health Education - statistics & numerical data | Cohort Studies | Prevention | Health promotion | Play schools | Reports | Research | Obesity in children | Methods | Education, Preschool
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14. Full Text Canadian Cardiovascular Society Guidelines for the Diagnosis and Management of Stable Ischemic Heart Disease
by Mancini, G.B. John, MD and Gosselin, Gilbert, MD and Chow, Benjamin, MD and Kostuk, William, MD and Stone, James, MD, PhD and Yvorchuk, Kenneth J., MD, CM and Abramson, Beth L., MD, MSc and Cartier, Raymond, MD and Huckell, Victor, MD and Tardif, Jean-Claude, MD and Connelly, Kim, MD and Ducas, John, MD and Farkouh, Michael E., MD, MSc and Gupta, Milan, MD and Juneau, Martin, MD and O’Neill, Blair, MD and Raggi, Paolo, MD and Teo, Koon, MBBCh, PhD and Verma, Subodh, MD and Zimmermann, Rodney, MD and Canadian Cardiovascular Society
Canadian Journal of Cardiology, ISSN 0828-282X, 2014, Volume 30, Issue 8, pp. 837 - 849
Abstract This overview provides a guideline for the management of stable ischemic heart disease. It represents the work of a primary and secondary panel of... 
Cardiovascular | FRACTIONAL FLOW RESERVE | CARDIAC & CARDIOVASCULAR SYSTEMS | OUTCOMES UTILIZING REVASCULARIZATION | LONG-TERM SURVIVAL | VENTRICULAR SYSTOLIC FUNCTION | QUALITY-OF-LIFE | 3-YEAR FOLLOW-UP | OPTIMAL MEDICAL THERAPY | CORONARY-ARTERY-DISEASE | CONVERTING-ENZYME-INHIBITORS | ELUTING STENT IMPLANTATION | Medical History Taking | Prognosis | Bundle-Branch Block - complications | Humans | Risk Factors | Calcium Channel Blockers - therapeutic use | Coronary Artery Disease - drug therapy | Health Behavior | Myocardial Revascularization | Stroke Volume | Coronary Angiography | Diagnostic Imaging | Exercise Test | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Coronary Artery Disease - diagnosis | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Myocardial Ischemia - therapy | Electrocardiography | Physical Examination | Platelet Aggregation Inhibitors - therapeutic use | Angiotensin Receptor Antagonists - therapeutic use | Myocardial Ischemia - diagnosis | Adrenergic beta-Antagonists - therapeutic use
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15. Full Text Medical Treatment and Revascularization Options in Patients With Type 2 Diabetes and Coronary Disease
by Mancini, G.B. John, MD and Farkouh, Michael E., MD, MSc and Brooks, Maria M., PhD and Chaitman, Bernard R., MD and Boden, William E., MD and Vlachos, Helen, MSc and Hartigan, Pamela M., PhD and Siami, Flora S., MPH and Sidhu, Mandeep S., MD and Bittner, Vera, MD, MSPH and Frye, Robert, MD and Fuster, Valentin, MD, PhD
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2016, Volume 68, Issue 10, pp. 985 - 995
Abstract Background There are scant outcomes data in patients with type 2 diabetes and stable coronary artery disease (CAD) stratified by detailed angiographic... 
Cardiovascular | Internal Medicine | percutaneous coronary intervention | stable ischemic heart disease | optimal medical therapy | coronary artery bypass grafting | MORTALITY | ARTERY-BYPASS SURGERY | CARDIAC & CARDIOVASCULAR SYSTEMS | METAANALYSIS | stable ischemic heart disease | MELLITUS | PREVALENCE | GRAFT-SURGERY | TRIAL | OUTCOMES | INTERVENTION | DRUG-ELUTING STENTS | Prospective Studies | Humans | Middle Aged | Male | Treatment Outcome | Randomized Controlled Trials as Topic | Stroke Volume | Coronary Artery Disease - therapy | Coronary Artery Disease - physiopathology | Time Factors | Coronary Artery Disease - complications | Coronary Artery Disease - pathology | Coronary Artery Bypass | Female | Diabetes Mellitus, Type 2 - complications | Percutaneous Coronary Intervention | Type 2 diabetes | Medical colleges | Care and treatment | Coronary heart disease | Epidemiology | Diabetes therapy | Transluminal angioplasty | Coronary artery bypass | Analysis | Plants | Stroke | Heart attacks | Laboratories | Mortality | Clinical trials | Patients | Clinical outcomes | Confidence intervals | Variables | Body mass index | Coronary vessels | Chronic obstructive pulmonary disease | Stratigraphy | Diabetes | Stents | Veins & arteries
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16. Full Text Design of the Future REvascularization Evaluation in patients with Diabetes mellitus: Optimal management of Multivessel disease (FREEDOM) Trial
by Farkouh, Michael E., MD, MSc and Dangas, George, MD, PhD and Leon, Martin B., MD and Smith, Craig, MD and Nesto, Richard, MD and Buse, John B., MD, PhD and Cohen, David J., MD, MSc and Mahoney, Elizabeth, ScD and Sleeper, Lynn, ScD and King, Spencer, MD and Domanski, Michael, MD and McKinlay, Sonja, PhD and Fuster, Valentin, MD, PhD
American Heart Journal, ISSN 0002-8703, 2008, Volume 155, Issue 2, pp. 215 - 223
Background Prior randomized trials suggested that revascularization of diabetic patients by coronary artery bypass grafting (CABG) produced results superior to... 
Cardiovascular | CARDIAC & CARDIOVASCULAR SYSTEMS | RANDOMIZATION | CLINICAL-TRIALS | BYPASS-SURGERY | QUALITY-OF-LIFE | HEALTH | TRANSLUMINAL CORONARY ANGIOPLASTY | DRUG ELUTING STENTS | ARTERY DISEASE | Epidemiologic Research Design | Drug-Eluting Stents | Diabetes Complications | Prospective Studies | Humans | Coronary Disease - therapy | Coronary Artery Bypass | Angioplasty, Balloon, Coronary | Myocardial Revascularization | Diabetics | Care and treatment | Diabetes | Diabetes therapy | Studies | Heart attacks | Drug therapy | Mortality | Coronary vessels
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