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humans (7) 7
science & technology (7) 7
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female (5) 5
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risk factors (3) 3
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alleles (2) 2
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1. Full Text Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction
by Do, Ron and Stitziel, Nathan O and Won, Hong-Hee and Jørgensen, Anders Berg and Duga, Stefano and Angelica Merlini, Pier and Kiezun, Adam and Farrall, Martin and Goel, Anuj and Zuk, Or and Guella, Illaria and Asselta, Rosanna and Lange, Leslie A and Peloso, Gina M and Auer, Paul L and Girelli, Domenico and Martinelli, Nicola and Farlow, Deborah N and DePristo, Mark A and Roberts, Robert and Stewart, Alexander F. R and Saleheen, Danish and Danesh, John and Epstein, Stephen E and Sivapalaratnam, Suthesh and Hovingh, G. Kees and Kastelein, John J and Samani, Nilesh J and Schunkert, Heribert and Erdmann, Jeanette and Shah, Svati H and Kraus, William E and Davies, Robert and Nikpay, Majid and Johansen, Christopher T and Wang, Jian and Hegele, Robert A and Hechter, Eliana and Marz, Winfried and Kleber, Marcus E and Huang, Jie and Johnson, Anew D and Li, Mingyao and Burke, Greg L and Gross, Myron and Liu, Yongmei and Assimes, Themistocles L and Heiss, Gerardo and Lange, Ethan M and Folsom, Aaron R and NHLBI Exome Sequencing Project
Nature (London), ISSN 0028-0836, 2015, Volume 518, Issue 7537, pp. 102 - +
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Genetics, Population | Myocardial Infarction - blood | Myocardial Infarction - genetics | Receptors, LDL - genetics | Apolipoprotein A-V | Genetic Predisposition to Disease - genetics | Apolipoproteins A - genetics | National Heart, Lung, and Blood Institute (U.S.) | Age Factors | United States | Humans | Middle Aged | Male | Mutation - genetics | Case-Control Studies | Exome - genetics | Age of Onset | Alleles | Coronary Artery Disease - genetics | Triglycerides - blood | Cholesterol, LDL - blood | Female | Heterozygote | Usage | Low density lipoproteins | Exome sequencing | Physiological aspects | Genetic aspects | Research | Diagnosis | Heart attack | Risk factors | Proteins | Studies | Algorithms | Heart attacks | Genes | Cardiovascular disease | Triglycerides | Mutation | Cholesterol | Index Medicus | Medicin och hälsovetenskap
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2. Full Text MAP kinase pathway alterations in BRAF -mutant melanoma patients with acquired resistance to combined RAF/MEK inhibition
by Wagle, Nikhil and Van Allen, Eliezer M and Treacy, Daniel J and Frederick, Dennie T and Cooper, Zachary A and Taylor-Weiner, Amaro and Rosenberg, Mara and Goetz, Eva M and Sullivan, Ryan J and Farlow, Deborah N and Friedrich, Dennis C and Anderka, Kristin and Perrin, Danielle and Johannessen, Cory M and McKenna, Aaron and Cibulskis, Kristian and Kryukov, Gregory and Hodis, Eran and Lawrence, Donald P and Fisher, Sheila and Getz, Gad and Gabriel, Stacey B and Carter, Scott L and Flaherty, Keith T and Wargo, Jennifer A and Garraway, Levi A
Cancer discovery, ISSN 2159-8274, 01/2014, Volume 4, Issue 1, pp. 61 - 68
Life Sciences & Biomedicine | Oncology | Science & Technology | Mitogen-Activated Protein Kinase Kinases - genetics | Skin Neoplasms - drug therapy | raf Kinases - antagonists & inhibitors | Humans | Middle Aged | Oximes - therapeutic use | Male | Antineoplastic Agents - therapeutic use | Melanoma - genetics | Imidazoles - therapeutic use | raf Kinases - genetics | Melanoma - metabolism | Signal Transduction | Pyrimidinones - therapeutic use | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Skin Neoplasms - metabolism | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Protein Kinase Inhibitors - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Skin Neoplasms - genetics | Mitogen-Activated Protein Kinases - genetics | Aged | Pyridones - therapeutic use | Mutation | Drug Resistance, Neoplasm - physiology | Mitogen-Activated Protein Kinases - metabolism | Index Medicus
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3. Full Text Large multiethnic Candidate Gene Study for C-reactive protein levels: identification of a novel association at CD36 in African Americans
by Ellis, Jaclyn and Lange, Ethan M and Li, Jin and Dupuis, Josee and Baumert, Jens and Walston, Jeremy D and Keating, Brendan J and Durda, Peter and Fox, Ervin R and Palmer, Cameron D and Meng, Yan A and Young, Taylor and Farlow, Deborah N and Schnabel, Renate B and Marzi, Carola S and Larkin, Emma and Martin, Lisa W and Bis, Joshua C and Auer, Paul and Ramachandran, Vasan S and Gabriel, Stacey B and Willis, Monte S and Pankow, James S and Papanicolaou, George J and Rotter, Jerome I and Ballantyne, Christie M and Gross, Myron D and Lettre, Guillaume and Wilson, James G and Peters, Ulrike and Koenig, Wolfgang and Tracy, Russell P and Redline, Susan and Reiner, Alex P and Benjamin, Emelia J and Lange, Leslie A
Human genetics, ISSN 0340-6717, 8/2014, Volume 133, Issue 8, pp. 985 - 995
Human Genetics | Gene Function | Molecular Medicine | Biomedicine | Metabolic Diseases | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Cardiovascular Diseases - etiology | Genetics, Population | Genetic Predisposition to Disease | Genome-Wide Association Study | Meta-Analysis as Topic | CD36 Antigens - genetics | Humans | Middle Aged | Risk Factors | Biomarkers - analysis | African Americans - genetics | Genetic Loci | C-Reactive Protein - metabolism | Polymorphism, Single Nucleotide - genetics | Adult | Female | Aged | Women | C-reactive protein | Analysis | Leptin | Genes | Genomics | African Americans | Health aspects | Index Medicus | Multi-ethnic | Inflammation | Candidate gene
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4. Full Text Candidate Gene Association Resource (CARe): Design, Methods, and Proof of Concept
by Musunuru, Kiran and Lettre, Guillaume and Young, Taylor and Farlow, Deborah N and Pirruccello, James P and Ejebe, Kenechi G and Keating, Brendan J and Yang, Qiong and Chen, Ming-Huei and Lapchyk, Nina and Crenshaw, Andrew and Ziaugra, Liuda and Rachupka, Anthony and Benjamin, Emelia J and Cupples, L. Adrienne and Fornage, Myriam and Fox, Ervin R and Heckbert, Susan R and Hirschhorn, Joel N and Newton-Cheh, Christopher and Nizzari, Marcia M and Paltoo, Dina N and Papanicolaou, George J and Patel, Sanjay R and Psaty, Bruce M and Rader, Daniel J and Redline, Susan and Rich, Stephen S and Rotter, Jerome I and Taylor, Herman A and Tracy, Russell P and Vasan, Ramachandran S and Wilson, James G and Kathiresan, Sekar and Fabsitz, Richard R and Boerwinkle, Eric and Gabriel, Stacey B and NHLBI Candidate Gene Assoc and NHLBI Candidate Gene Association Resource and for the NHLBI Candidate Gene Association Resource
Circulation. Cardiovascular genetics, ISSN 1942-325X, 06/2010, Volume 3, Issue 3, pp. 267 - 275
Genetics | Lipids | Epidemiology | Cardiac & Cardiovascular Systems | Genetics & Heredity | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Biological and medical sciences | Medical genetics | Medical sciences | European Continental Ancestry Group - genetics | Humans | African Americans - genetics | Databases, Genetic | Genetic Association Studies - methods | Genotype | Cholesterol, HDL - genetics | Cholesterol, LDL - genetics | Phenotype | Pilot Projects | Triglycerides - blood | Cholesterol, HDL - blood | Cholesterol, LDL - blood | Polymorphism, Single Nucleotide | Triglycerides - genetics | Research Design | Cohort Studies | Index Medicus | blood pressure | epidemiology | lipids | diabetes
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5. Full Text Exome sequencing in suspected monogenic dyslipidemias
by Stitziel, Nathan O and Peloso, Gina M and Abifadel, Marianne and Cefalu, Angelo B and Fouchier, Sigrid and Motazacker, M. Mahdi and Tada, Hayato and Larach, Daniel B and Awan, Zuhier and Haller, Jorge F and Pullinger, Clive R and Varret, Mathilde and Rabès, Jean-Pierre and Noto, Davide and Tarugi, Patrizia and Kawashiri, Masa-Aki and Nohara, Atsushi and Yamagishi, Masakazu and Risman, Marjorie and deo, Rahul and Ruel, Isabelle and Shendure, Jay and Nickerson, Deborah A and Wilson, James G and Rich, Stephen S and Gupta, Namrata and Farlow, Deborah N and Neale, Benjamin M and Daly, Mark J and Kane, John P and Freeman, Mason W and Genest, Jacques and Rader, Daniel J and Mabuchi, Hiroshi and Kastelein, John J. P and Hovingh, G. Kees and Averna, Maurizio R and Gabriel, Stacey and Boileau, Catherine and Kathiresan, Sekar and NHLBI Grand Opportunity Exome and NHLBI Grand Opportunity Exome Sequencing Project Family Studies Project Team
Circulation. Cardiovascular genetics, ISSN 1942-325X, 2015, Volume 8, Issue 2, pp. 343 - 350
lipids | exome | genetics | human | DNA sequencing | Cardiac & Cardiovascular Systems | Genetics & Heredity | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Exome | Dyslipidemias - genetics | Humans | Female | Male | High-Throughput Nucleotide Sequencing | Metabolism, Inborn Errors - genetics | Index Medicus | Mendelian Genetics | Exome sequencing
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6. Full Text Large-Scale Candidate Gene Analysis in Whites and African Americans Identifies IL6R Polymorphism in Relation to Atrial Fibrillation The National Heart, Lung, and Blood Institute's Candidate Gene Association Resource (CARe) Project
by Schnabel, Renate B and Kerr, Kathleen F and Lubitz, Steven A and Alkylbekova, Ermeg L and Marcus, Gregory M and Sinner, Moritz F and Magnani, Jared W and Wolf, Philip A and Deo, Rajat and Lloyd-Jones, Donald M and Lunetta, Kathryn L and Mehra, Reena and Levy, Daniel and Fox, Ervin R and Arking, Dan E and Mosley, Thomas H and Mueller-Nurasyid, Martina and Young, Taylor R and Wichmann, H. -Erich and Seshai, Sudha and Farlow, Deborah N and Rotter, Jerome I and Soliman, Elsayed Z and Glazer, Nicole L and Wilson, James G and Breteler, Monique M. B and Sotoodehnia, Nona and Newton-Cheh, Christopher and Kaeaeb, Stefan and Ellinor, Patrick T and Alonso, Alvaro and Benjamin, Emelia J and Heckbert, Susan R and Candidate Gene Assoc Resource CARe and Candidate Gene Association Resource (CARe) Atrial Fibrillation/Electrocardiography Working Group and for the Candidate Gene Association Resource (CARe) Atrial Fibrillation/Electrocardiography Working Group
Circulation. Cardiovascular genetics, ISSN 1942-325X, 10/2011, Volume 4, Issue 5, pp. 557 - U188
C-REACTIVE PROTEIN | DESIGN | cohort study | VARIANTS | single nucleotide polymorphism | INTERLEUKIN-6 | ATHEROSCLEROSIS RISK | race/ethnicity | epidemiology | atrial fibrillation | EUROPEAN ANCESTRY | INFLAMMATION | DISEASE | CHROMOSOME 4Q25 | ISCHEMIC-STROKE | Single nucleotide polymorphism | Race/ethnicity | Epidemiology | Atrial fibrillation | Cohort study | Cardiac & Cardiovascular Systems | Genetics & Heredity | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Cardiology. Vascular system | Heart | Neurology | Cardiac dysrhythmias | Medical genetics | Biological and medical sciences | Vascular diseases and vascular malformations of the nervous system | Medical sciences | Chromosome aberrations | European Continental Ancestry Group - genetics | National Heart, Lung, and Blood Institute (U.S.) | Receptors, Interleukin-6 - genetics | United States | Humans | Middle Aged | Risk Factors | African Americans - genetics | Male | Atrial Fibrillation - genetics | Chromosomes, Human, Pair 4 | Alleles | Female | Stroke - epidemiology | Aged | Polymorphism, Single Nucleotide | Cohort Studies | Index Medicus
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7. Full Text Genome-Wide Association Study of Cardiac Structure and Systolic Function in African Americans: The Candidate Gene Association Resource (CARe) Study
by Fox, Ervin R and Musani, Solomon K and Barbalic, Maja and Lin, Honghuang and Yu, Bing and Ogunyankin, Kofo O and Smith, Nicholas L and Kutlar, Abdullah and Glazer, Nicole L and Post, Wendy S and Paltoo, Dina N and Dries, Daniel L and Farlow, Deborah N and Duarte, Christine W and Kardia, Sharon L and Meyers, Kristin J and Sun, Yan V and Arnett, Donna K and Patki, Amit A and Sha, Jin and Cui, Xiangqui and Samdarshi, Tandaw E and Penman, Alan D and Bibbins-Domingo, Kirsten and Bůžková, Petra and Benjamin, Emelia J and Bluemke, David A and Morrison, Alanna C and Heiss, Gerardo and Carr, J Jeffrey and Tracy, Russell P and Mosley, Thomas H and Taylor, Herman A and Psaty, Bruce M and Heckbert, Susan R and Cappola, Thomas P and Vasan, Ramachandran S
Circulation. Cardiovascular genetics, ISSN 1942-325X, 02/2013, Volume 6, Issue 1, pp. 37 - 46
Genome-wide association studies | Left ventricular mass genetics | Echocardiography | Left atrium genetics | Ethnic | Cardiac & Cardiovascular Systems | Genetics & Heredity | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Heart - anatomy & histology | European Continental Ancestry Group - genetics | Genome-Wide Association Study | Diastole | Heart - physiology | Humans | Middle Aged | African Americans - genetics | Genotype | Male | Systole | Phenotype | Female | Aged | Polymorphism, Single Nucleotide | Cohort Studies | Index Medicus | ethnic | genome-wide association studies | echocardiography | left ventricular mass genetics
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8. Full Text Genome-Wide Association Study of Coronary Heart Disease and Its Risk Factors in 8,090 African Americans: The NHLBI CARe Project
: e1001300
by Guillaume Lettre and Cameron D Palmer and Taylor Young and Kenechi G Ejebe and Hooman Allayee and Emelia J Benjamin and Franklyn Bennett and Donald W Bowden and Aravinda Chakravarti and Al Dreisbach and Deborah N Farlow and Aaron R Folsom and Myriam Fornage and Terrence Forrester and Ervin Fox and Christopher A Haiman and Jaana Hartiala and Tamara B Harris and Stanley L Hazen and Susan R Heckbert and Brian E Henderson and Joel N Hirschhorn and Brendan J Keating and Stephen B Kritchevsky and Emma Larkin and Mingyao Li and Megan E Rudock and Colin A McKenzie and James B Meigs and Yang A Meng and Tom H Mosley Jr and Anne B Newman and Christopher H Newton-Cheh and Dina N Paltoo and George J Papanicolaou and Nick Patterson and Wendy S Post and Bruce M Psaty and Atif N Qasim and Liming Qu and Daniel J Rader and Susan Redline and Muredach P Reilly and Alexander P Reiner and Stephen S Rich and Jerome I Rotter and Yongmei Liu and Peter Shrader and David S Siscovick and W H Wilson Tang and Herman A Taylor Jr and Russell P Tracy and Ramachandran S Vasan and Kevin M Waters and Rainford Wilks and James G Wilson and Richard R Fabsitz and Stacey B Gabriel and Sekar Kathiresan and Eric Boerwinkle
PLoS genetics, ISSN 1553-7390, 02/2011, Volume 7, Issue 2
Studies | African Americans | Cardiovascular disease | Genetics | Cholesterol
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9. Full Text Large-Scale Candidate Gene Analysis in Whites and African-Americans Identifies IL6R Polymorphism in Relation to Atrial Fibrillation: The NHLBI CARe Project
by Schnabel, Renate B and Kerr, Kathleen F and Lubitz, Steven A and Alkylbekova, Ermeg L and Marcus, Gregory M and Sinner, Moritz F and Magnani, Jared W and Wolf, Philip A and Deo, Rajat and Lloyd-Jones, Donald M and Lunetta, Kathryn L and Mehra, Reena and Levy, Daniel and Fox, Ervin R and Arking, Dan E and Mosley, Thomas H and Mueller, Martina and Young, Taylor and Wichmann, Erich and Seshadri, Sudha and Farlow, Deborah N and Rotter, Jerome I and Soliman, Elsayed Z and Glazer, Nicole L and Wilson, James G and Breteler, Monique M.B and Sotoodehnia, Nona and Newton-Cheh, Christopher and Kääb, Stefan and Ellinor, Patrick T and Alonso, Alvaro and Benjamin, Emelia J and Heckbert, Susan R and
Circulation. Cardiovascular genetics, ISSN 1942-325X, 10/2011, Volume 4, Issue 5, pp. 557 - 564
epidemiology | atrial fibrillation | cohort study | race | ethnicity | single nucleotide polymorphism
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