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1. Full Text The Hunger Genes: Pathways to Obesity
by van der Klaauw, Agatha A and Farooqi, I. Sadaf
Cell (Cambridge), ISSN 0092-8674, 03/2015, Volume 161, Issue 1, pp. 119 - 132
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Animals | Diet | Energy Metabolism | Hypothalamus - physiology | Obesity - complications | Humans | Obesity - therapy | Feeding Behavior | Obesity - genetics | Obesity - metabolism | Obesity | Hunger | Genes | Type 2 diabetes | Physiological aspects | Prevalence studies (Epidemiology) | Index Medicus
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2. Full Text Loss-of-Function Mutation in the Dioxygenase-Encoding FTO Gene Causes Severe Growth Retardation and Multiple Malformations
by Boissel, Sarah and Reish, Orit and Proulx, Karine and Kawagoe-Takaki, Hiroko and Sedgwick, Barbara and Yeo, Giles S.H and Meyre, David and Golzio, Christelle and Molinari, Florence and Kadhom, Noman and Etchevers, Heather C and Saudek, Vladimir and Farooqi, I. Sadaf and Froguel, Philippe and Lindahl, Tomas and O'Rahilly, Stephen and Munnich, Arnold and Colleaux, Laurence
American journal of human genetics, ISSN 0002-9297, 2009, Volume 85, Issue 1, pp. 106 - 111
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | General aspects. Genetic counseling | Medical genetics | Biological and medical sciences | Molecular and cellular biology | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Proteins - genetics | Amino Acid Sequence | Genetic Predisposition to Disease | Sequence Alignment | Animals | Pedigree | Humans | Molecular Sequence Data | Alpha-Ketoglutarate-Dependent Dioxygenase FTO | Mutation | Growth Disorders - genetics | Abnormalities, Multiple - genetics | Proteins | Cardiovascular system | Obesity | Genes | Polymorphism | Index Medicus | Life Sciences | Genetics | Human genetics | Report
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3. Full Text Obesity and the brain: How convincing is the addiction model?
by Ziauddeen, Hisham and Farooqi, I. Sadaf and Fletcher, Paul C
Nature reviews. Neuroscience, ISSN 1471-003X, 04/2012, Volume 13, Issue 4, pp. 279 - 286
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Vertebrates: nervous system and sense organs | Obesity | Biological and medical sciences | General aspects. Models. Methods | Metabolic diseases | Medical sciences | Models, Theoretical | Obesity - psychology | Brain - physiopathology | Humans | Hyperphagia - physiopathology | Obesity - physiopathology | Hyperphagia - psychology | Behavior, Addictive - psychology | Behavior, Addictive - physiopathology | Psychological aspects | Care and treatment | Dopamine | Addiction | Compulsive eating | Physiological aspects | Reward (Psychology) | Health aspects | Index Medicus
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4. Full Text Leptin: A pivotal regulator of human energy homeostasis
by Sadaf Farooqi, I and O'Rahilly, Stephen
The American journal of clinical nutrition, ISSN 0002-9165, 03/2009, Volume 89, Issue 3, pp. 980S - 984S
Fundamental and applied biological sciences. Psychology | Feeding. Feeding behavior | Biological and medical sciences | Vertebrates: anatomy and physiology, studies on body, several organs or systems | Energy Intake - physiology | Leptin - physiology | Adipose Tissue - metabolism | Animals | Homeostasis - physiology | Humans | Energy Metabolism - physiology | Leptin - deficiency | Physiological aspects | Homeostasis | Research | Leptin | Proteins | Genotype & phenotype | Signal transduction | Peptides | Nutrition | Hormones | Mutation | Index Medicus | Abridged Index Medicus
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5. Full Text Modulation of Blood Pressure by Central Melanocortinergic Pathways
by Greenfield, Jerry R and Miller, Jeffrey W and Keogh, Julia M and Henning, Elana and Satterwhite, Julie H and Cameron, Gregory S and Astruc, Beatrice and Mayer, John P and Brage, Soren and See, Teik Choon and Lomas, David J and O'Rahilly, Stephen and Farooqi, I. Sadaf
The New England journal of medicine, ISSN 0028-4793, 01/2009, Volume 360, Issue 1, pp. 44 - 52
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Receptor, Melanocortin, Type 4 - deficiency | Overweight - complications | Prevalence | Blood Pressure - genetics | Humans | Male | Receptor, Melanocortin, Type 4 - metabolism | Catecholamines - urine | Obesity - genetics | Dose-Response Relationship, Drug | Overweight - metabolism | Heart Rate - physiology | Adult | Female | Blood Pressure - drug effects | Blood Pressure - physiology | Hypertension - genetics | Sleep - physiology | Double-Blind Method | Signal Transduction | Obesity - complications | Heart Rate - genetics | Autonomic Nervous System - physiology | Overweight - genetics | Genotype | Receptor, Melanocortin, Type 4 - agonists | Receptor, Melanocortin, Type 4 - genetics | Hypertension - metabolism | Obesity - metabolism | Cross-Over Studies | Hypertension - complications | Heterozygote | Mutation | Measurement | Physiological aspects | Control | Blood pressure | Methods | Obesity | Signal transduction | Genetics | Index Medicus | Abridged Index Medicus
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6. Full Text Human disorders of leptin action
by Sadaf Farooqi, I and O'Rahilly, Stephen
Journal of endocrinology, ISSN 0022-0795, 2014, Volume 223, Issue 1, pp. T63 - T70
Obesity | Signal transduction | Receptors | Leptin | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology
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7. Full Text Genetic approaches to understanding human obesity
by Ramachandrappa, Shwetha and Farooqi, I. Sadaf
The Journal of clinical investigation, ISSN 0021-9738, 06/2011, Volume 121, Issue 6, pp. 2080 - 2086
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Receptor, Melanocortin, Type 4 - deficiency | Dietary Fats - metabolism | Genomic Imprinting | Receptors, Leptin - genetics | Humans | Body Weight - genetics | Obesity - genetics | Melanocortins - physiology | Leptin - physiology | Adaptation, Physiological - genetics | Melanocortins - genetics | Mice, Mutant Strains | Obesity - etiology | Energy Metabolism - genetics | Energy Metabolism - physiology | Genome-Wide Association Study | Genetic Association Studies | Gene Dosage | Leptin - genetics | Receptor, Melanocortin, Type 4 - genetics | Syndrome | Obesity - metabolism | Animals | Receptors, Leptin - physiology | Obesity - epidemiology | Environment | Mice | Body Weight - physiology | Leptin - deficiency | Receptor, Melanocortin, Type 4 - physiology | Genetic research | Obesity | Body weight | Public health | Index Medicus | Abridged Index Medicus | Review
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8. Full Text Genetics of Obesity in Humans
by Farooqi, I. Sadaf and O’Rahilly, Stephen
Endocrine reviews, ISSN 0163-769X, 12/2006, Volume 27, Issue 7, pp. 710 - 718
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Proprotein Convertase 1 - genetics | Humans | Receptor, trkB - physiology | Obesity - physiopathology | Leptin - genetics | Receptor, Melanocortin, Type 4 - genetics | Receptor, trkB - genetics | Signal Transduction - genetics | Mutation - genetics | Body Weight - genetics | Obesity - genetics | Pro-Opiomelanocortin - physiology | Melanocortins - physiology | Leptin - physiology | Proprotein Convertase 1 - physiology | Mutation - physiology | Melanocortins - genetics | Signal Transduction - physiology | Body Weight - physiology | Pro-Opiomelanocortin - genetics | Neurosecretory Systems - physiopathology | Receptor, Melanocortin, Type 4 - physiology | Index Medicus
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