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Nature Immunology, ISSN 1529-2908, 10/2012, Volume 13, Issue 10, pp. 972 - 980
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2012, Volume 109, Issue 10, pp. 3891 - 3896
Immature thymocytes expressing autoreactive T-cell receptors (TCR) can adopt differing cell fates: clonal deletion by apoptosis or deviation into alternative... 
T lymphocytes | Thymocytes | Clonal deletion | Transgenic animals | Natural killer T cells | Genes | Negative selection | Signatures | T cell antigen receptors | Apoptosis | Glycolysis | Nuclear receptor | Immune tolerance | Thymus | APOPTOSIS | thymus | TCR EXPRESSION | MULTIDISCIPLINARY SCIENCES | glycolysis | INDUCTION | THYMOCYTES | BCL-2 | immune tolerance | ORPHAN STEROID-RECEPTOR | IN-VIVO | NEGATIVE SELECTION | NUR77 | nuclear receptor | CENTRAL TOLERANCE | Proto-Oncogene Proteins - metabolism | Nuclear Receptor Subfamily 4, Group A, Member 1 - genetics | Peptides - chemistry | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Transcription Factors - metabolism | Cell Lineage | Animals | Cell Nucleus - metabolism | Bcl-2-Like Protein 11 | Time Factors | T-Lymphocytes, Regulatory - cytology | Thymocytes - cytology | Cell Differentiation | Membrane Proteins - metabolism | Mice | Nuclear Receptor Subfamily 4, Group A, Member 1 - physiology | Cloning | Physiological aspects | Genetic aspects | Genetic transcription | Research | T cells | Cell differentiation | Gene expression | Enzymes | T cell receptors | Rodents | Liver | TOR protein | Tricarboxylic acid cycle | Transcription factors | Immunoregulation | Nur77 protein | Transgenic mice | AKT protein | Lymphocytes T | Nuclear receptors | T-cell receptor | Cell fate | Foxp3 protein | Differentiation | BIM protein | Index Medicus | Biological Sciences
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2018, Volume 1799, pp. 341 - 351
Transgenic methods to manipulate CD4 T lymphocytes in vivo via forced expression of TCR transgenes and targeted "knockout" of individual genes by Cre-lox... 
In vitro gene expression | Electroporation | microRNA | CD4 | T lymphocyte transfection | Th2 | Index Medicus | electroporation | in vitro gene expression
Journal Article
Cell Reports, ISSN 2211-1247, 10/2018, Volume 25, Issue 4, pp. 871 - 883
Perturbations in the transcriptional programs specifying epidermal differentiation cause diverse skin pathologies ranging from impaired barrier function to... 
skin | single-cell RNA-seq | keratinocyte | epidermis | POPULATION | INHIBITION | HUMAN HAIR FOLLICLE | SKIN | DIFFERENTIATION | LARGE GENE LISTS | EXPRESSION | T-CELLS | PSORIASIS | ALOPECIA | CELL BIOLOGY
Journal Article
Cell Reports, ISSN 2211-1247, 08/2019, Volume 28, Issue 8, pp. 2169 - 2181.e4
Coordinate control of T cell proliferation, survival, and differentiation are essential for host protection from pathogens and cancer. Long-lived memory cells,... 
miR-16 | cell cycle | T cell memory | microRNA | miRNA | miR-15a | CD127 | miR-15b | IL-7 receptor | Argonaute HITS-CLIP | EFFECTOR | POPULATION | IMMUNITY | ACTIVATION | TRANSCRIPTION | GENE-EXPRESSION | ARGONAUTE | PROLIFERATION | INDUCTION | MICRORNAS | CELL BIOLOGY | Index Medicus
Journal Article
Nature immunology, ISSN 1529-2908, 10/2012, Volume 13, Issue 10, pp. 972 - 980
The transcription factor FoxP3 partakes dominantly in the specification and function of FoxP3 + CD4 + T regulatory cells (Tregs), but is neither strictly... 
Journal Article
Journal Article
Journal Article
01/2009, ISBN 9781109497175
Establishment of immune tolerance within an organism requires proper education and regulation of myriad cell types. As the organ where T cell central tolerance... 
Immunology | Developmental biology
Dissertation
01/2009, ISBN 9781109497175, Volume 70, Issue 11
Establishment of immune tolerance within an organism requires proper education and regulation of myriad cell types. As the organ where T cell central tolerance... 
Book Chapter
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