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Brain Structure and Function, ISSN 1863-2653, 3/2018, Volume 223, Issue 2, pp. 1001 - 1015
The brain vasculature can be investigated in different ways ranging from in vivo to biochemical analysis. Immunohistochemistry is a simple and powerful... 
Immunohistochemistry | Neurology | Neurosciences | Biomedicine | Antigen retrieval | Alzheimer’s disease | Cerebral blood flow | Blood vessels | Cell Biology | MRI | ALZHEIMERS-DISEASE | LAMININ | ANATOMY & MORPHOLOGY | TISSUE | HYPOPERFUSION | PATHOLOGY | NEUROSCIENCES | MOUSE MODEL | BLOOD-VESSELS | MICE | Alzheimer's disease | Brain - diagnostic imaging | Blood Vessels - metabolism | Blood Vessels - pathology | Humans | tau Proteins - metabolism | Alzheimer Disease - pathology | Brain - metabolism | tau Proteins - genetics | Amyloid beta-Protein Precursor - metabolism | Disease Models, Animal | Presenilin-1 - genetics | Proteoglycans - metabolism | Mice, Transgenic | Antigens - metabolism | Mutation - genetics | Immunohistochemistry - methods | Collagen - metabolism | Magnetic Resonance Imaging | Amyloid beta-Protein Precursor - genetics | Animals | Image Processing, Computer-Assisted | Presenilin-1 - metabolism | Alzheimer Disease - metabolism | Lectins | Mice | Alzheimer Disease - diagnostic imaging | Alzheimer Disease - genetics | Neuroimaging | Brain | Animal models | Biochemical analysis | Transgenic mice | Glial cells | Paraffin | Blood flow | Neurological diseases | Dentate gyrus | Magnetic resonance imaging | Tau protein | Perfusion | Transgenic animals | Presenilin 1 | Rodents | Microvasculature | Hippocampus
Journal Article
LANCET, ISSN 0140-6736, 07/2019, Volume 394, Issue 10193, pp. 139 - 147
Background Stroke thrombolysis with alteplase is currently recommended 0-4.5 h after stroke onset. We aimed to determine whether perfusion imaging can identify... 
MISMATCH | MEDICINE, GENERAL & INTERNAL | MULTICENTER | ALTEPLASE | ACUTE ISCHEMIC-STROKE | REPERFUSION | DIFFUSION | TIME | ONSET
Journal Article
Stem Cell Research & Therapy [E], ISSN 1757-6512, 04/2017, Volume 8, Issue 1, pp. 96 - 14
Background: In the field of experimental stem cell therapy, intra-arterial (IA) delivery yields the best results concerning, for example, migrated cell number... 
Adipose tissue-derived stem cell | Biochemistry, Genetics and Molecular Biology (miscellaneous) | Cell tracking | Medicine (miscellaneous) | Cell engraftment | Focal ischaemia | High-field MRI | MCA occlusion | Molecular Medicine | Rodent model | Journal Article | Cell Biology | MOUSE-BRAIN | MEDICINE, RESEARCH & EXPERIMENTAL | MYOCARDIAL-INFARCTION | BONE-MARROW | ADMINISTRATION ROUTE | MONONUCLEAR-CELLS | VERSUS-HOST-DISEASE | CELL BIOLOGY | MESENCHYMAL STROMAL CELLS | IN-VIVO | SENSITIVE MRI | PROCOAGULANT ACTIVITY | Rats, Wistar | Cells, Cultured | Adipose Tissue - cytology | Rats | Male | Stem Cells - cytology | Infarction, Middle Cerebral Artery - pathology | Infarction, Middle Cerebral Artery - therapy | Stem Cells - metabolism | Cell Tracking | Stem Cell Transplantation | Magnetic Resonance Imaging | Animals | Cerebral Arteries - pathology | Infarction, Middle Cerebral Artery - diagnostic imaging | Cell Movement | Disease Models, Animal | Neuroimaging | Cell culture | Nuclear magnetic resonance--NMR | Adipose tissue | Leukocyte migration | Stem cell transplantation | Cytotoxicity | Iron | Carotid arteries | Allografts | Ischemia | Cerebral blood flow | Rodents | Labeling | Drug dosages | Cerebral infarction | Stroke | Injection | Investigations | Brain research | Magnetic resonance imaging | Cell number | Stem cells | Cell migration | Veins & arteries
Journal Article
PLoS ONE, ISSN 1932-6203, 2014, Volume 9, Issue 1, p. e85849
Background: A recent study suggests that patients with persistent occlusion of the middle cerebral artery (MCA) following treatment with recombinant tissue... 
MATRIX METALLOPROTEINASES | TISSUE-PLASMINOGEN-ACTIVATOR | BRAIN-INJURY | MULTIDISCIPLINARY SCIENCES | FOCAL CEREBRAL-ISCHEMIA | MATRIX-METALLOPROTEINASE-9 | REPERFUSION | THROMBOLYSIS | MECHANISMS | TRANSIENT | HISTOPATHOLOGY | Tumor Necrosis Factor-alpha - metabolism | Apoptosis - drug effects | Heat-Shock Proteins - metabolism | Mice, Inbred C57BL | Caspase 3 - metabolism | Male | Stroke - drug therapy | Tissue Plasminogen Activator - therapeutic use | Brain - drug effects | Brain - metabolism | Stroke - pathology | Fibrinolytic Agents - pharmacology | Matrix Metalloproteinase 9 - metabolism | Stroke - metabolism | Animals | Tissue Plasminogen Activator - pharmacology | Fibrinolytic Agents - therapeutic use | Brain - pathology | Mice | Thromboembolism - drug therapy | Thromboembolism - metabolism | Interleukin-6 - metabolism | Thromboembolism - pathology | Disease Models, Animal | Brain | Medical research | Interleukins | Tissue plasminogen activator | Medicine, Experimental | Heat shock proteins | Thrombin | Models | Thromboembolism | Apoptosis | Occlusion | Nuclear magnetic resonance--NMR | Interleukin | Matrix metalloproteinase | Hemorrhage | Caspase-3 | t-Plasminogen activator | Mimicry | Interleukin 6 | Histopathology | Ischemia | Blood-brain barrier | Lasers | Cerebral blood flow | Rodents | Tumor necrosis factor-TNF | Metalloproteinase | Recombinant | Cerebral infarction | Stroke | Cytokines | Cortex | Caspase | Inflammation | Histology | Hsp70 protein | Injection | Tumor necrosis factor-α | Gene expression | Patients | Thrombolysis | Gelatinase B | Medicine | Neurology | Correlation analysis | Infarction | Laboratory animals | Immunofluorescence | Nuclear magnetic resonance | NMR
Journal Article
Molecular Therapy - Nucleic Acids, ISSN 2162-2531, 2013, Volume 2, Issue 2, pp. e73 - e73
Delivery of drugs and macromolecules to the central nervous system (CNS) is hindered by the blood–brain barrier (BBB). Several approaches have been used to... 
AAV | ultrasound | blood–brain barrier | Blood-brain barrier | Ultrasound | blood-brain barrier | GUIDED FOCUSED ULTRASOUND | MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | GENE DELIVERY | MICROBUBBLES | BARRIER DISRUPTION | TRANSGENE EXPRESSION | ADENOASSOCIATED VIRUS VECTORS | NEURONS | CENTRAL-NERVOUS-SYSTEM | TARGETED DELIVERY | Methods - Original
Journal Article
Journal Article
European Neurology, ISSN 0014-3022, 04/2016, Volume 75, Issue 3-4, pp. 170 - 177
Background: Acute stroke is a medical emergency with various clinical presentations. Since the introduction of systemic thrombolytic treatment, stroke... 
Original Paper | Stroke | Time window | Emergency Department | Stroke mimics | Prospective Studies | Humans | Middle Aged | Stroke - diagnosis | Male | Emergency Service, Hospital - statistics & numerical data | Ischemic Attack, Transient - diagnosis | Young Adult | Adolescent | Aged, 80 and over | Adult | Female | Aged
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