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by Okbay, Aysu and Baselmans, B.M.L and Neve, Jan-Emmanuel and Turley, Patrick and Nivard, Michel and Fontana, M.A and Meddens, S.F.W and Linnér, R.K and Rietveld, C.A and Derringer, J and Gratten, Jacob and Lee, James J and Liu, J.Z and Vlaming, Ronald and SAhluwalia, T and Buchwald, J and Cavadino, Alana and Frazier-Wood, Alexis C and Furlotte, N.A and Garfield, V and Geisel, M.H and Gonzalez, Juan R and Haitjema, S and Karlsson, Robert and Der Laan, S.W and Ladwig, Karl-Heinz and Lahti, Jari and Lee, Sven and Lind, Penelope and Liu, T and Matteson, L and Mihailov, Evelin and Miller, Mike and CMinica, C and MNolte, I and Mook-Kanamori, Dennis and Most, Peter and Oldmeadow, Christopher and Qian, Yong and Raitakari, Olli and Rawal, R and Realo, A and Rueedi, R and Schmidt, B and Smith, Albert Vernon and Stergiakouli, Evangelia and Tanaka, Toshiko and Taylor, Kent and Wedenoja, J and Wellmann, J and Westra, Harm-Jan and MWillems, S and Zhao, W and Study, LifeLines Cohort and Amin, Najaf and Bakshi, A and Boyle, Patricia and Cherney, S and Cox, S.R and Davies, Gail and Davis, Oliver S and Ding, Jun and Direk, Nese and Eibich, P and Emeny, Rebecca and Fatemifar, G and Faul, J.D and Ferrucci, Luigi and Forstner, Aneas and Gieger, Christian and Gupta, R and Harris, Tamara B and Harris, Juliette and Holliday, Elizabeth and Hottenga, Jouke Jan and Jager, Philip and Kaakinen, Marika and Kajantie, Eero and Karhunen, V and Kolcic, Ivana and Kumari, Meena and Launer, Lenore and Franke, Lude and Li-Gao, R and Koini, M and Loukola, Anu and Marques-Vidal, P and Montgomery, Grant and Mosing, Miriam and Paternoster, Lavinia and Pattie, Alison and Petrovic, Katja and Pulkki-R'back, L and Quaye, Lydia and R'ikkönen, K and Rudan, Igor and Scott, Rodney and Smith, Jennifer A and Sutin, A.R and Trzaskowski, M and ... and LifeLines Cohort Study
Nature Genetics, ISSN 1061-4036, 06/2016, Volume 48, Issue 6, pp. 624 - 633
Journal Article
by Lu, Yingchang and Day, Felix R and Gustafsson, Stefan and Buchkovich, Martin L and Na, Jianbo and Bataille, Veronique and Cousminer, Diana L and Dastani, Zari and ng, Alexander W and Esko, Tõnu and Evans, David M and Falchi, Mario and Feitosa, Mary F and Ferreira, Teresa and Hedman, Åsa K and Haring, Robin and Hysi, Pirro G and Iles, Mark M and Justice, Anne E and Kanoni, Stavroula and Lagou, Vasiliki and Li, Rui and Li, Xin and Locke, Adam and Lu, Chen and Mägi, Reedik and Perry, John R. B and Pers, Tune H and Qi, Qibin and Sanna, Marianna and Schmidt, Ellen M and Scott, William R and Shungin, Dmitry and Teumer, Alexander and Vinkhuyzen, Anna A. E and Walker, Ryan W and Westra, Harm-Jan and Zhang, Mingfeng and Zhang, Weihua and Zhao, Jing Hua and Zhu, Zhihong and Afzal, Uzma and Ahluwalia, Tarunveer Singh and Bakker, Stephan J. L and Bellis, Claire and Bonnefond, Amélie and Borodulin, Katja and Buchman, Aron S and Cederholm, Tommy and Choh, Auey C and Choi, Hyung Jin and Curran, Joanne E and de Groot, Lisette C. P. G. M and de Jager, Philip L and Dhonukshe-Rutten, Rosalie A. M and Enneman, Anke W and Eury, Elodie and Evans, Daniel S and Forsen, Tom and Frieich, Nele and Fumeron, Frédéric and Garcia, Melissa E and Gärtner, Simone and Han, Bok-Ghee and Havulinna, Aki S and Hayward, Caroline and Hernandez, Dena and Hillege, Hans and Ittermann, Till and Kent, Jack W and Kolcic, Ivana and Laatikainen, Tiina and Lahti, Jari and Mateo Leach, Irene and Lee, Christine G and Lee, Jong-Young and Liu, Tian and Liu, Youfang and Lobbens, Stéphane and Loh, Marie and Lyytikäinen, Leo-Pekka and Medina-Gomez, Carolina and Michaëlsson, Karl and Nalls, Mike A and Nielson, Carrie M and Oozageer, Laticia and Pascoe, Laura and Paternoster, Lavinia and Polašek, Ozren and Ripatti, Samuli and Sarzynski, Mark A and Shin, Chan Soo and Narančić, Nina Smolej and Spira, Dominik and Srikanth, Priya and Steinhagen-Thiessen, Elisabeth and Sung, Yun Ju and Swart, Karin M. A and Taittonen, Leena and Tanaka, Toshiko and ... and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Institutionen för odontologi and Umeå universitet and Medicin
Nature communications, ISSN 2041-1723, 2016, Volume 7, Issue 1, p. 10495
Journal Article
by Okbay, Aysu and Baselmans, Bart M L and De Neve, Jan-Emmanuel and Turley, Patrick and Nivard, Michel G and Fontana, Mark Alan and Meddens, S Fleur W and Linnér, Richard Karlsson and Rietveld, Cornelius A and Derringer, Jaime and Gratten, Jacob and Lee, James J and Liu, Jimmy Z and de Vlaming, Ronald and Ahluwalia, Tarunveer S and Buchwald, Jadwiga and Cavadino, Alana and Frazier-Wood, Alexis C and Furlotte, Nicholas A and Garfield, Victoria and Geisel, Marie Henrike and Gonzalez, Juan R and Haitjema, Saskia and Karlsson, Robert and van der Laan, Sander W and Ladwig, Karl-Heinz and Lahti, Jari and van der Lee, Sven J and Lind, Penelope A and Liu, Tian and Matteson, Lindsay and Mihailov, Evelin and Miller, Michael B and Minica, Camelia C and Nolte, Ilja M and Mook-Kanamori, Dennis and van der Most, Peter J and Oldmeadow, Christopher and Qian, Yong and Raitakari, Olli and Rawal, Rajesh and Realo, Anu and Rueedi, Rico and Schmidt, Börge and Smith, Albert V and Stergiakouli, Evie and Tanaka, Toshiko and Taylor, Kent and Thorleifsson, Gudmar and Wedenoja, Juho and Wellmann, Juergen and Westra, Harm-Jan and Willems, Sara M and Zhao, Wei and Amin, Najaf and Bakshi, Andrew and Bergmann, Sven and Bjornsdottir, Gyda and Boyle, Patricia A and Cherney, Samantha and Cox, Simon R and Davies, Gail and Davis, Oliver S P and Ding, Jun and Direk, Nese and Eibich, Peter and Emeny, Rebecca T and Fatemifar, Ghazaleh and Faul, Jessica D and Ferrucci, Luigi and Forstner, Andreas J and Gieger, Christian and Gupta, Richa and Harris, Tamara B and Harris, Juliette M and Holliday, Elizabeth G and Hottenga, Jouke-Jan and De Jager, Philip L and Kaakinen, Marika A and Kajantie, Eero and Karhunen, Ville and Kolcic, Ivana and Kumari, Meena and Launer, Lenore J and Franke, Lude and Li-Gao, Ruifang and Liewald, David C and Koini, Marisa and Loukola, Anu and Marques-Vidal, Pedro and Montgomery, Grant W and Mosing, Miriam A and Paternoster, Lavinia and Pattie, Alison and Petrovic, Katja E and Pulkki-Råback, Laura and Quaye, Lydia and Räikkönen, Katri and Rudan, Igor and Scott, Rodney J and ... and LifeLines Cohort Study
Nature genetics, ISSN 1061-4036, 11/2016, Volume 48, Issue 12, pp. 1591 - 1591
Journal Article
by Okbay, Aysu and Baselmans, Bart M. L and De Neve, Jan-Emmanuel and Turley, Patrick and Nivard, Michel G and Fontana, Mark Alan and Meddens, S. Fleur W and Linner, Richard Karlsson and Rietveld, Cornelius A and Derringer, Jaime and Gratten, Jacob and Lee, James J and Liu, Jimmy Z and de Vlaming, Ronald and Ahluwalia, Tarunveer S and Buchwald, Jadwiga and Cavadino, Alana and Frazier-Wood, Alexis C and Furlotte, Nicholas A and Garfield, Victoria and Geisel, Marie Henrike and Gonzalez, Juan R and Haitjema, Saskia and Karlsson, Robert and van der Laan, Sander W and Ladwig, Karl-Heinz and Lahti, Jari and van der Lee, Sven J and Lind, Penelope A and Liu, Tian and Matteson, Lindsay and Mihailov, Evelin and Miller, Michael B and Minica, Camelia C and Nolte, Ilja M and Mook-Kanamori, Dennis and van der Most, Peter J and Oldmeadow, Christopher and Qian, Yong and Raitakari, Olli and Rawal, Rajesh and Realo, Anu and Rueedi, Rico and Schmidt, Borge and Smith, Albert V and Stergiakouli, Evie and Tanaka, Toshiko and Taylor, Kent and Thorleifsson, Gudmar and Wedenoja, Juho and Wellmann, Juergen and Westra, Harm-Jan and Willems, Sara M and Zhao, Wei and Amin, Najaf and Bakshi, Anew and Bergmann, Sven and Bjornsdottir, Gyda and Boyle, Patricia A and Cherney, Samantha and Cox, Simon R and Davies, Gail and Davis, Oliver S. P and Ding, Jun and Direk, Nese and Eibich, Peter and Emeny, Rebecca T and Fatemifar, Ghazaleh and Faul, Jessica D and Ferrucci, Luigi and Forstner, Aneas J and Gieger, Christian and Gupta, Richa and Harris, Tamara B and Harris, Juliette M and Holliday, Elizabeth G and Hottenga, Jouke-Jan and De Jager, Philip L and Kaakinen, Marika A and Kajantie, Eero and Karhunen, Ville and Kolcic, Ivana and Kumari, Meena and Launer, Lenore J and Franke, Lude and Li-Gao, Ruifang and Liewald, David C and Koini, Marisa and Loukola, Anu and Marques-Vidal, Peo and Montgomery, Grant W and Mosing, Miriam A and Paternoster, Lavinia and Pattie, Alison and Petrovic, Katja E and Pulkki-Raback, Laura and Quaye, Lydia and Raikkonen, Katri and Rudan, Igor and Scott, Rodney J and ... and LifeLines Cohort Study
Nature Genetics, ISSN 1061-4036, 08/2016, Volume 48, Issue 8, pp. 970 - 970
  Aysu Okbay, Bart M L Baselmans, Jan-Emmanuel De Neve, Patrick Turley, Michel G Nivard, Mark Alan Fontana, S Fleur W Meddens, Richard Karlsson Linnér,... 
Journal Article
by Okbay, A and Baselmans, BML and De Neve, JE and Turley, P and Nivard, MG and Fontana, MA and Meddens, SFW and Linner, RK and Rietveld, CA and Derringer, J and Gratten, J and Lee, JJ and Liu, JZ and de Vlaming, R and Ahluwalia, TS and Buchwald, J and Cavadino, A and Frazier-Wood, AC and Furlotte, NA and Garfield, V and Geisel, MH and Gonzalez, JR and Haitjema, S and Karlsson, R and van der Laan, SW and Ladwig, KH and Lahti, J and van der Lee, SJ and Lind, PA and Liu, T and Matteson, L and Mihailov, E and Miller, MB and Minica, CC and Nolte, IM and Mook-Kanamori, D and van der Most, PJ and Oldmeadow, C and Qian, Y and Raitakari, O and Rawal, R and Realo, A and Rueedi, R and Schmidt, B and Smith, AV and Stergiakouli, E and Tanaka, T and Taylor, K and Thorleifsson, G and Wedenoja, J and Wellmann, J and Westra, HJ and Willems, SM and Zhao, W and Amin, N and Bakshi, A and Bergmann, S and Bjornsdottir, G and Boyle, PA and Cherney, S and Cox, SR and Davies, G and Davis, OSP and Ding, J and Direk, N and Eibich, P and Emeny, RT and Fatemifar, G and Faul, JD and Ferrucci, L and Forstner, AJ and Gieger, C and Gupta, R and Harris, TB and Harris, JM and Holliday, EG and Hottenga, JJ and De Jager, PL and Kaakinen, MA and Kajantie, E and Karhunen, V and Kolcic, I and Kumari, M and Launer, LJ and Franke, L and Li-Gao, R and Liewald, DC and Koini, M and Loukola, A and Marques-Vidal, P and Montgomery, GW and Mosing, MA and Paternoster, L and Pattie, A and Petrovic, KE and Pulkki-Raback, L and Quaye, L and Raikkonen, K and Rudan, I and Scott, RJ and ... and LifeLines Cohort Study
NATURE GENETICS, ISSN 1061-4036, 12/2016, Volume 48, Issue 12, pp. 1591 - 1591
Journal Article
by Okbay, A and Baselmans, BML and De Neve, JE and Turley, P and Nivard, MG and Fontana, MA and Meddens, SFW and Linner, RK and Rietveld, CA and Derringer, J and Gratten, J and Lee, JJ and Liu, JZ and de Vlaming, R and Ahluwalia, TS and Buchwald, J and Cavadino, A and Frazier-Wood, AC and Furlotte, NA and Garfield, V and Geisel, MH and Gonzalez, JR and Haitjema, S and Karlsson, R and van der Laan, SW and Ladwig, KH and Lahti, J and van der Lee, SJ and Lind, PA and Liu, T and Matteson, L and Mihailov, E and Miller, MB and Minica, CC and Nolte, IM and Mook-Kanamori, D and van der Most, PJ and Oldmeadow, C and Qian, Y and Raitakari, O and Rawal, R and Realo, A and Rueedi, R and Schmidt, B and Smith, AV and Stergiakouli, E and Tanaka, T and Taylor, K and Thorleifsson, G and Wedenoja, J and Wellmann, J and Westra, HJ and Willems, SM and Zhao, W and Amin, N and Bakshi, A and Bergmann, S and Bjornsdottir, G and Boyle, PA and Cherney, S and Cox, SR and Davies, G and Davis, OSP and Ding, J and Direk, N and Eibich, P and Emeny, RT and Fatemifar, G and Faul, JD and Ferrucci, L and Forstner, AJ and Gieger, C and Gupta, R and Harris, TB and Harris, JM and Holliday, EG and Hottenga, JJ and De Jager, PL and Kaakinen, MA and Kajantie, E and Karhunen, V and Kolcic, I and Kumari, M and Launer, LJ and Franke, L and Li-Gao, RF and Liewald, DC and Koini, M and Loukola, A and Marques-Vidal, P and Montgomery, GW and Mosing, MA and Paternoster, L and Pattie, A and Petrovic, KE and Pulkki-Raback, L and Quaye, L and Raikkonen, K and Rudan, I and Scott, RJ and ... and LifeLines Cohort Study
NATURE GENETICS, ISSN 1061-4036, 08/2016, Volume 48, Issue 8, pp. 970 - 970
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2016, Volume 67, Issue 10, pp. 1200 - 1210
Abstract Background Statins are first-line therapy for cardiovascular disease prevention, but their systemic effects across lipoprotein subclasses, fatty... 
Cardiovascular | Internal Medicine | drug development | Mendelian randomization | metabolomics | cholesterol lowering | lipoproteins | COHORT PROFILE | CARDIAC & CARDIOVASCULAR SYSTEMS | BIOMARKER | VARIANTS | FATTY-ACID-COMPOSITION | RISK | TRIGLYCERIDES | LDL CHOLESTEROL | CORONARY-HEART-DISEASE | ASSOCIATION | EPIDEMIOLOGY | Hydroxymethylglutaryl CoA Reductases - drug effects | Mendelian Randomization Analysis - methods | Magnetic Resonance Spectroscopy - methods | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Male | United Kingdom | Cardiovascular Diseases - genetics | Forecasting | Metabolomics - methods | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Finland | Cardiovascular Diseases - blood | Adult | Female | Retrospective Studies | Hydroxymethylglutaryl CoA Reductases - blood | Hydroxymethylglutaryl CoA Reductases - genetics | Medical colleges | Metabolites | Pharmacy | Genomics | Genetic research | Drugstores | Fatty acids | Epidemiology | Statins | Public health | Cardiovascular agents | Lipids | Cholesterol | LDL-C, low-density lipoprotein cholesterol | CVD, cardiovascular disease | IDL, intermediate-density lipoprotein | VLDL, very-low-density lipoprotein | HMGCR, HMG-CoA reductase | NMR, nuclear magnetic resonance | HDL, high-density lipoprotein | Original Investigation
Journal Article
by Taylor, Peter N and Porcu, Eleonora and Chew, Shelby and Campbell, Purdey J and Traglia, Michela and Brown, Suzanne J and Mullin, Benjamin H and Shihab, Hashem A and Min, Josine and Walter, Klaudia and Memari, Yasin and Huang, Jie and Barnes, Michael R and Beilby, John P and Charoen, Pimphen and Danecek, Petr and Dudbridge, Frank and Forgetta, Vincenzo and Greenwood, Celia and Grundberg, Elin and Johnson, Andrew D and Hui, Jennie and Lim, Ee M and McCarthy, Shane and Muddyman, Dawn and Panicker, Vijay and Perry, John R. B and Bell, Jordana T and Yuan, Wei and Relton, Caroline and Gaunt, Tom and Schlessinger, David and Abecasis, Goncalo and Cucca, Francesco and Surdulescu, Gabriela L and Woltersdorf, Wolfram and Zeggini, Eleftheria and Zheng, Hou-Feng and Toniolo, Daniela and Dayan, Colin M and Naitza, Silvia and Walsh, John P and Spector, Tim and Smith, George Davey and Durbin, Richard and Richards, J. Brent and Sanna, Serena and Soranzo, Nicole and Timpson, Nicholas J and Wilson, Scott G and Turki, Saeed Al and Anderson, Carl and Anney, Richard and Antony, Dinu and Artigas, Maria Soler and Ayub, Muhammad and Balasubramaniam, Senduran and Barrett, Jeffrey C and Barroso, Inês and Beales, Phil and Bentham, Jamie and Bhattacharya, Shoumo and Birney, Ewan and Blackwood, Douglas and Bobrow, Martin and Bochukova, Elena and Bolton, Patrick and Bounds, Rebecca and Boustred, Chris and Breen, Gerome and Calissano, Mattia and Carss, Keren and Chatterjee, Krishna and Chen, Lu and Ciampi, Antonio and Cirak, Sebhattin and Clapham, Peter and Clement, Gail and Coates, Guy and Collier, David and Cosgrove, Catherine and Cox, Tony and Craddock, Nick and Crooks, Lucy and Curran, Sarah and Curtis, David and Daly, Allan and Day-Williams, Aaron and Day, Ian N. M and Down, Thomas and Du, Yuanping and Dunham, Ian and Edkins, Sarah and Ellis, Peter and Evans, David and Faroogi, Sadaf and Fatemifar, Ghazaleh and Fitzpatrick, David R and Flicek, Paul and Flyod, James and ... and UK10K Consortium and UK0K Consortium and The UK10K Consortium
Nature Communications, ISSN 2041-1723, 2015, Volume 6, Issue 1, p. 5681
Journal Article
by Timpson, Nicholas J and Walter, Klaudia and Min, Josine L and Tachmazidou, Ioanna and Malerba, Giovanni and Shin, So-Youn and Chen, Lu and Futema, Marta and Southam, Lorraine and Iotchkova, Valentina and Cocca, Massimiliano and Huang, Jie and Memari, Yasin and McCarthy, Shane and Danecek, Petr and Muddyman, Dawn and Mangino, Massimo and Menni, Cristina and Perry, John R.B and Ring, Susan M and Gaye, Amadou and Dedoussis, George and Farmaki, Aliki-Eleni and Burton, Paul and Talmud, Philippa J and Gambaro, Giovanni and Spector, Tim D and Smith, George Davey and Durbin, Richard and Richards, J Brent and Humphries, Steve E and Zeggini, Eleftheria and Soranzo, Nicole and Turki, Saeed Al and Anderson, Carl and Anney, Richard and Antony, Dinu and Artigas, Maria Soler and Ayub, Muhammad and Balasubramaniam, Senduran and Barrett, Jeffrey C and Barroso, Iněs and Beales, Phil and Bentham, Jamie and Bhattacharya, Shoumo and Birney, Ewan and Blackwood, Douglas and Bobrow, Martin and Bochukova, Elena and Bolton, Patrick and Bounds, Rebecca and Boustred, Chris and Breen, Gerome and Calissano, Mattia and Carss, Keren and Chatterjee, Krishna and Ciampi, Antonio and Cirak, Sebhattin and Clapham, Peter and Clement, Gail and Coates, Guy and Collier, David and Cosgrove, Catherine and Cox, Tony and Craddock, Nick and Crooks, Lucy and Curran, Sarah and Curtis, David and Daly, Allan and Day-Williams, Aaron and Day, Ian N.M and Down, Thomas and Du, Yuanping and Dunham, Ian and Edkins, Sarah and Ellis, Peter and Evans, David and Faroogi, Sadaf and Fatemifar, Ghazaleh and Fitzpatrick, David R and Flicek, Paul and Flyod, James and Foley, A. Reghan and Franklin, Christopher S and Gallagher, Louise and Gaunt, Tom and Geihs, Matthias and Geschwind, Daniel and Greenwood, Celia and Griffin, Heather and Grozeva, Detelina and Guo, Xueqin and Guo, Xiaosen and Gurling, Hugh and Hart, Deborah and Hendricks, Audrey and Holmans, Peter and Howie, Bryan and Huang, Liren and Hubbard, Tim and ... and UK10K Consortium and UK1OK Consortium Members and UK1OK consortium members
Nature Communications, ISSN 2041-1723, 2014, Volume 5, Issue 1, p. 4871
Journal Article