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1. Full Text Atezolizumab (atezo) therapy for upper tract (UT) urothelial carcinoma (UC): Subgroup analysis of the single-arm international SAUL study in pretreated locally advanced/metastatic urinary tract carcinoma
by Sternberg, Cora N and Loriot, Yohann and Tambaro, Rosa and Buttigliero, Consuelo and Morelli, Franco and Papai, Zsuzsanna and Retz, Margitta and Necchi, Andrea and Van Der Heijden, Michiel Simon and Faust, Guy and Cardona Zorrilla, Andres Felipe and Lainez, Nuria and Panni, Stefano and Etxaniz, Olatz and Krieger, Laurence and Mendez Vidal, Maria Jose José and Los, Maartje and de Ducla, Sabine and Fear, Simon and Merseburger, Axel Stuart
Journal of clinical oncology, ISSN 0732-183X, 02/2020, Volume 38, Issue 6_suppl, pp. 488 - 488
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2. Full Text Effect of Hydroxychloroquine in Hospitalized Patients with Covid-19
by Horby, Peter and Mafham, Marion and Linsell, Louise and Bell, Jennifer L and Staplin, Natalie and Emberson, Jonathan R and Wiselka, Martin and Ustianowski, Andrew and Elmahi, Einas and Prudon, Benjamin and Whitehouse, Tony and Felton, Timothy and Williams, John and Faccenda, Jakki and Underwood, Jonathan and Baillie, J. Kenneth and Chappell, Lucy C and Faust, Saul N and Jaki, Thomas and Jeffery, Katie and Lim, Wei Shen and Montgomery, Alan and Rowan, Kathryn and Tarning, Joel and Watson, James A and White, Nicholas J and Juszczak, Edmund and Haynes, Richard and Landray, Martin J and The RECOVERY Collaborative Group and RECOVERY Collaborative Grp and RECOVERY Collaborative Group
The New England journal of medicine, ISSN 0028-4793, 11/2020, Volume 383, Issue 21, pp. 2030 - 2040
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Hydroxychloroquine - therapeutic use | Pandemics | Antiviral Agents - therapeutic use | Coronavirus Infections - drug therapy | Humans | Middle Aged | Pneumonia, Viral - drug therapy | Male | Hospitalization | Hydroxychloroquine - adverse effects | Coronavirus Infections - mortality | Respiration, Artificial | COVID-19 | SARS-CoV-2 | Antiviral Agents - adverse effects | Treatment Failure | Aged, 80 and over | Betacoronavirus | Female | Aged | Pneumonia, Viral - mortality | Heart | Hydroxychloroquine | Arrhythmia | Mortality | Chloroquine | Clinical trials | Fatalities | Ventilation | Death | Coronaviruses | Index Medicus | Abridged Index Medicus
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3. Full Text Children are not COVID-19 super spreaders: time to go back to school
by Munro, Alasdair P S and Faust, Saul N
Archives of disease in childhood, ISSN 0003-9888, 07/2020, Volume 105, Issue 7, pp. 618 - 619
Life Sciences & Biomedicine | Pediatrics | Science & Technology | Betacoronavirus - pathogenicity | Coronavirus Infections - prevention & control | Quarantine - legislation & jurisprudence | Humans | Pandemics - prevention & control | Education, Distance | COVID-19 | Coronavirus Infections - transmission | Pneumonia, Viral - transmission | SARS-CoV-2 | Coronavirus Infections - epidemiology | Pneumonia, Viral - epidemiology | Pneumonia, Viral - prevention & control | Policy Making | Quarantine - statistics & numerical data | Education - legislation & jurisprudence | Public Health - legislation & jurisprudence | Child | Schools | Biomedical research | Comorbidity | Households | Families & family life | Infections | Coronaviruses | Seroconversion | Children & youth | Severe acute respiratory syndrome coronavirus 2 | Disease transmission | Surveillance | Influenza | Contact tracing | Population | Adults | Children | Public health | Index Medicus | Abridged Index Medicus
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4. Full Text Addendum to: Children are not COVID-19 super spreaders: time to go back to school
by Munro, Alasdair Peter Stuart and Faust, Saul N
Archives of disease in childhood, ISSN 0003-9888, 02/2021, Volume 106, Issue 2, pp. e9 - e9
Epidemics | Vigilance | COVID-19 diagnostic tests | Households | Disease reservoirs | Infections | Serology | Coronaviruses | Children & youth | Severe acute respiratory syndrome coronavirus 2 | Seroepidemiology | Polymerase chain reaction | COVID-19 | Disease transmission | Social distancing | Contact tracing | Adults | Children | Schools | Public health | Index Medicus | Abridged Index Medicus
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5. Full Text Preliminary Assessment of the Efficacy of a T-Cell-Based Influenza Vaccine, MVA-NP+M1, in Humans
by Patrick J. Lillie and Tamara K. Berthoud and Timothy J. Powell and Teresa Lambe and Caitlin Mullarkey and Alexandra J. Spencer and Matthew Hamill and Yanchun Peng and Marie-Eve Blais and Christopher J. A. Duncan and Susanne H. Sheehy and Tom Havelock and Saul N. Faust and Rob Lambkin Williams and Anthony Gilbert and John Oxford and Tao Dong and Adrian V. S. Hill and Sarah C. Gilbert
Clinical infectious diseases, ISSN 1058-4838, 7/2012, Volume 55, Issue 1, pp. 19 - 25
T lymphocytes | Influenza vaccines | Antigens | Volunteerism | Influenza A virus | Vaccination | Viruses | Orthomyxoviridae | ARTICLES AND COMMENTARIES | Dosage | Symptoms | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Biological and medical sciences | Viral diseases of the respiratory system and ent viral diseases | Infectious diseases | Medical sciences | Human viral diseases | Viral diseases | Interferon-gamma | Influenza Vaccines - administration & dosage | Humans | Middle Aged | RNA-Binding Proteins - immunology | Influenza Vaccines - adverse effects | Virus Shedding | Administration, Intranasal | Antibodies, Viral - blood | Antigens, Viral - immunology | Pilot Projects | HLA-A2 Antigen | Influenza Vaccines - immunology | Adolescent | Adult | Antibodies, Viral - immunology | Influenza A virus - immunology | Influenza, Human - virology | T-Lymphocytes - immunology | Viral Core Proteins - immunology | Viral Matrix Proteins - immunology | Influenza, Human - prevention & control | Influenza, Human - immunology | Patient safety | Immunization | Vaccines | Influenza | Index Medicus | and Commentaries
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6. Lyme disease: Summary of NICE guidance
by Cruickshank, Maria and O'Flynn, Norma and Faust, Saul N and Guideline Comm and Guideline Committee
BMJ (Online), ISSN 0959-8146, 2018, Volume 361, p. k1261
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Academies and Institutes | Borrelia burgdorferi | Lyme Disease - epidemiology | Humans | United Kingdom | Lyme Disease Vaccines | Health Knowledge, Attitudes, Practice | Anti-Bacterial Agents - therapeutic use | Animals | Counseling | Lyme Disease - diagnosis | Fatigue - microbiology | Patient Education as Topic
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7. Full Text Lack of Evidence for an Unmet Need to Treat Clostridium difficile Infection in Infants Aged <2 Years: Expert Recommendations on How to Address This Issue
by Saul N. Faust and Mark H. Wilcox and Aleksandra Banaszkiewicz and Emilio Bouza and Josette Raymond and Dale N. Gerding
Clinical infectious diseases, ISSN 1058-4838, 3/2015, Volume 60, Issue 6, pp. 912 - 918
VIEWPOINTS | Diarrhea | Pediatrics | Clinical trial | Infants | C. difficile infection | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Anti-Bacterial Agents - therapeutic use | Humans | Clostridium difficile | Clostridium Infections - drug therapy | Female | Infant | Male | Clinical Trials as Topic | Babies | Clinical trials | Bacteria | Bacterial infections | Medical treatment | Index Medicus
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8. It's Time to Put Children and Young People First During the Global COVID-19 Pandemic
by Faust, Saul N and Munro, Alasdair P. S
JAMA pediatrics, ISSN 2168-6203, 02/2021, Volume 175, Issue 2, pp. 127 - 128
Life Sciences & Biomedicine | Pediatrics | Science & Technology | Students - statistics & numerical data | Social Isolation - psychology | Humans | Adolescent | Child Welfare - statistics & numerical data | Psychology, Adolescent | COVID-19 - epidemiology | Child | COVID-19 - psychology | Psychology, Child | Severe acute respiratory syndrome coronavirus 2 | COVID-19 | Pandemics | Inflammation | Coronaviruses | Children | Public health
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9. Full Text Low-Dose Nitric Oxide as Targeted Anti-biofilm Adjunctive Therapy to Treat Chronic Pseudomonas aeruginosa Infection in Cystic Fibrosis
by Howlin, Robert P and Cathie, Katrina and Hall-Stoodley, Luanne and Cornelius, Victoria and Duignan, Caroline and Allan, Raymond N and Fernandez, Bernadette O and Barraud, Nicolas and Bruce, Ken D and Jefferies, Johanna and Kelso, Michael and Kjelleberg, Staffan and Rice, Scott A and Rogers, Geraint B and Pink, Sandra and Smith, Caroline and Sukhtankar, Priya S and Salib, Rami and Legg, Julian and Carroll, Mary and Daniels, Thomas and Feelisch, Martin and Stoodley, Paul and Clarke, Stuart C and Connett, Gary and Faust, Saul N and Webb, Jeremy S
Molecular therapy, ISSN 1525-0016, 09/2017, Volume 25, Issue 9, pp. 2104 - 2116
Pseudomonas aeruginosa | nitric oxide | cystic fibrosis | Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Biofilms - drug effects | Sputum - microbiology | Pseudomonas Infections - drug therapy | Humans | Middle Aged | Bacterial Load | Pseudomonas aeruginosa - drug effects | Cystic Fibrosis - complications | Nitric Oxide - administration & dosage | Pseudomonas Infections - microbiology | Randomized Controlled Trials as Topic | Dose-Response Relationship, Drug | Pseudomonas Infections - blood | Young Adult | Time Factors | Adolescent | Adult | Nitric Oxide - metabolism | Anti-Bacterial Agents - administration & dosage | Statistical analysis | Laboratories | Clinical trials | Chronic infection | Cystic fibrosis | Biomass | Morbidity | Inhalation | Biofilms | Antibiotics | Dispersal | Nitric oxide | Antibiotic tolerance | Sputum | Bacteria | Blood pressure | Tobramycin | Ceftazidime | Colonization | Index Medicus | Original
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10. Full Text Five winters of pneumococcal serotype replacement in UK carriage following PCV introduction
by Gladstone, Rebecca A and Jefferies, Johanna M and Tocheva, Anna S and Beard, Kate R and Garley, David and Chong, Wei Wei and Bentley, Stephen D and Faust, Saul N and Clarke, Stuart C
Vaccine, ISSN 0264-410X, 2015, Volume 33, Issue 17, pp. 2015 - 2021
Allergy and Immunology | Serotype replacement | Pneumococcal vaccines | Whole genome | Next generation sequencing | Streptococcus pneumoniae | Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Heptavalent Pneumococcal Conjugate Vaccine - immunology | Streptococcus pneumoniae - classification | Humans | Carrier State - microbiology | Child, Preschool | Infant | Male | Pneumococcal Vaccines - administration & dosage | Streptococcus pneumoniae - immunology | Vaccines, Conjugate - immunology | Pneumococcal Infections - immunology | Streptococcus pneumoniae - isolation & purification | Time Factors | Streptococcus pneumoniae - genetics | Female | Pneumococcal Infections - microbiology | Seasons | Nasopharynx - microbiology | Serotyping | Heptavalent Pneumococcal Conjugate Vaccine - administration & dosage | Genome, Bacterial | Serogroup | Genotype | United Kingdom | Sequence Analysis, DNA | Vaccines, Conjugate - administration & dosage | Pneumococcal Infections - prevention & control | Pneumococcal Vaccines - immunology | High-Throughput Nucleotide Sequencing | Confidence intervals | Medical research | Pneumonia | Hospitals | Biomedical research | Surveillance | Genomes | Vaccines | Public health | Age | Children & youth | Streptococcus infections | Index Medicus
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11. Diagnostic Test Accuracy of a 2-Transcript Host RNA Signature for Discriminating Bacterial vs Viral Infection in Febrile Children
by Herberg, Jethro A and Herberg, Jethro A and Kaforou, Myrsini and Kaforou, Myrsini and Wright, Victoria J and Wright, Victoria J and Shailes, Hannah and Shailes, Hannah and Eleftherohorinou, Hariklia and Eleftherohorinou, Hariklia and Hoggart, Clive J and Hoggart, Clive J and Cebey-López, Miriam and Cebey-López, Miriam and Carter, Michael J and Carter, Michael J and Janes, Victoria A and Janes, Victoria A and Gormley, Stuart and Gormley, Stuart and Shimizu, Chisato and Shimizu, Chisato and Tremoulet, Adriana H and Tremoulet, Adriana H and Barendregt, Anouk M and Barendregt, Anouk M and Salas, Antonio and Salas, Antonio and Kanegaye, John and Kanegaye, John and Pollard, Andrew J and Pollard, Andrew J and Faust, Saul N and Faust, Saul N and Patel, Sanjay and Patel, Sanjay and Kuijpers, Taco and Kuijpers, Taco and Martinón-Torres, Federico and Martinón-Torres, Federico and Burns, Jane C and Burns, Jane C and Coin, Lachlan J. M and Coin, Lachlan J. M and Levin, Michael and Levin, Michael and IRIS Consortium
JAMA : the journal of the American Medical Association, ISSN 0098-7484, 08/2016, Volume 316, Issue 8, pp. 835 - 845
Prospective Studies | Area Under Curve | Cytoskeletal Proteins - genetics | Fever - microbiology | Humans | Child, Preschool | Infant | Male | Risk | Gene Expression Profiling | Virus Diseases - complications | RNA - genetics | Bacterial Infections - complications | Bacterial Infections - genetics | Antigens - blood | Fever - blood | Sensitivity and Specificity | Cytoskeletal Proteins - blood | Female | Virus Diseases - genetics | Severity of Illness Index | Diagnosis, Differential | RNA - analysis | Logistic Models | Biomarkers - blood | Genetic Markers | Coinfection - virology | Fever - virology | Coinfection - microbiology | Virus Diseases - diagnosis | Coinfection - diagnosis | Bacterial Infections - diagnosis | Anti-Bacterial Agents - administration & dosage | RNA - blood | Antigens - genetics | Infections | Ribonucleic acid--RNA | Diagnostic tests | Children & youth
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12. Good outlook for patients with confirmed Lyme neuroborreliosis
by Faust, Saul N and Barton, Stephen and Rayment, Caroline and O'Flynn, Norma
BMJ (Online), ISSN 0959-8146, 2018, Volume 361
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology
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13. Full Text A phase III, open-label, randomised multicentre study to evaluate the immunogenicity and safety of a booster dose of two different reduced antigen diphtheria-tetanus-acellular pertussis-polio vaccines, when co-administered with measles-mumps-rubella vaccine in 3 and 4-year-old healthy children in the UK
by Marlow, Robin and Kuriyakose, Sherine and Mesaros, Narcisa and Han, Htay Htay and Tomlinson, Richard and Faust, Saul N and Snape, Matthew D and Pollard, Andrew J and Finn, Adam
Vaccine, ISSN 0264-410X, 04/2018, Volume 36, Issue 17, pp. 2300 - 2306
RCT | Child | dTap-IPV | Preschool booster | Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Rubella | Antigens | Immune response | Laboratories | Vaccination | Vaccines | Diphtheria | Whooping cough | Pertussis | Studies | Randomization | Immunogenicity | Poliomyelitis | Measles | Mumps | Safety | Children | Tetanus | Age | Index Medicus
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