JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2010, Volume 56, Issue 25, pp. e50 - e103
Cardiovascular | Internal Medicine | risk factor assessment | cardiovascular screening of asymptomatic adults | cardiovascular risk assessment | ACCF/AHA practice guidelines | detection of coronary artery disease | subclinical coronary artery disease | asymptomatic adults | Practice guidelines (Medicine) | Adults | Diagnosis | Cardiovascular diseases | Cardiology
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2016, Volume 68, Issue 16, pp. 1769 - 1780
Abstract Background Evidence suggests that interleukin (IL)-1β is important in the pathogenesis of atherosclerosis and its complications and that inhibiting...
Cardiovascular | Internal Medicine | C-reactive protein | interleukin-1 | inflammation | homeostasis model assessment | RHEUMATOID-ARTHRITIS | MACROPHAGE PLASTICITY | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | INTERLEUKIN-1 RECEPTOR ANTAGONIST | TUMOR-NECROSIS-FACTOR | VASCULAR FUNCTION | CARDIOVASCULAR-DISEASE | E-DEFICIENT MICE | Atherosclerosis - drug therapy | Double-Blind Method | Antibodies, Monoclonal - pharmacology | Humans | Middle Aged | Antibodies, Monoclonal - therapeutic use | Atherosclerosis - complications | Male | Arteries - drug effects | Glucose Intolerance - complications | Female | Diabetes Mellitus, Type 2 - complications | Interleukin-1beta - antagonists & inhibitors | Type 2 diabetes | Complications and side effects | Blood circulation disorders | Medical colleges | Care and treatment | Interleukins | Atherosclerosis | Development and progression | Research institutes | Glucose | Dextrose | Proteins | Heart attacks | Nuclear magnetic resonance--NMR | Cytokines | Mortality | Inflammation | Diabetes | Patients | CI, confidence interval | T2DM, type 2 diabetes mellitus | HOMA, homeostasis model assessment | IL-1RA, interleukin-1 receptor antagonist | HbA1c, glycosylated hemoglobin | MRI, magnetic resonance imaging | GMR, geometric mean ratio | IL, interleukin | PWV, pulsed wave velocity | IGT, impaired glucose tolerance | Original Investigation | hs-CRP, high-sensitivity C-reactive protein
Cardiovascular | Internal Medicine | C-reactive protein | interleukin-1 | inflammation | homeostasis model assessment | RHEUMATOID-ARTHRITIS | MACROPHAGE PLASTICITY | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | INTERLEUKIN-1 RECEPTOR ANTAGONIST | TUMOR-NECROSIS-FACTOR | VASCULAR FUNCTION | CARDIOVASCULAR-DISEASE | E-DEFICIENT MICE | Atherosclerosis - drug therapy | Double-Blind Method | Antibodies, Monoclonal - pharmacology | Humans | Middle Aged | Antibodies, Monoclonal - therapeutic use | Atherosclerosis - complications | Male | Arteries - drug effects | Glucose Intolerance - complications | Female | Diabetes Mellitus, Type 2 - complications | Interleukin-1beta - antagonists & inhibitors | Type 2 diabetes | Complications and side effects | Blood circulation disorders | Medical colleges | Care and treatment | Interleukins | Atherosclerosis | Development and progression | Research institutes | Glucose | Dextrose | Proteins | Heart attacks | Nuclear magnetic resonance--NMR | Cytokines | Mortality | Inflammation | Diabetes | Patients | CI, confidence interval | T2DM, type 2 diabetes mellitus | HOMA, homeostasis model assessment | IL-1RA, interleukin-1 receptor antagonist | HbA1c, glycosylated hemoglobin | MRI, magnetic resonance imaging | GMR, geometric mean ratio | IL, interleukin | PWV, pulsed wave velocity | IGT, impaired glucose tolerance | Original Investigation | hs-CRP, high-sensitivity C-reactive protein
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2016, Volume 68, Issue 20, pp. 2201 - 2216
Abstract Ischemic heart disease is a complex disease process caused by the development of coronary atherosclerosis, with downstream effects on the left...
Cardiovascular | Internal Medicine | atherosclerosis | coronary artery disease | noninvasive imaging | acute coronary syndrome | calcium | myocardial infarction | FRACTIONAL FLOW RESERVE | FUNCTIONAL RECOVERY | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | CT ANGIOGRAPHY | PROGNOSTIC VALUE | DIAGNOSTIC PERFORMANCE | INTRACORONARY THROMBUS | POSITRON-EMISSION-TOMOGRAPHY | HYPERINTENSE PLAQUE | CORONARY-ARTERY-DISEASE | Tomography, X-Ray Computed - methods | Reproducibility of Results | Magnetic Resonance Imaging, Cine - methods | Myocardial Ischemia - diagnosis | Humans | CT imaging | Medical colleges | Atherosclerosis | Chronic diseases | Development and progression | Myocardial ischemia | Heart attack | Heart | Medical imaging | Ischemia | Coronary vessels | Tomography | Cardiovascular disease | Acute coronary syndromes | Angina pectoris | Blood clots | Veins & arteries | CAC, coronary artery calcium | CTA, computed tomography angiography | FFR, fractional flow reserve | ACS, acute coronary syndrome | MI, myocardial infarction | LGE, late gadolinium enhancement | The Present and Future | SPECT, single-photon emission computed tomography | CMR, cardiac magnetic resonance
Cardiovascular | Internal Medicine | atherosclerosis | coronary artery disease | noninvasive imaging | acute coronary syndrome | calcium | myocardial infarction | FRACTIONAL FLOW RESERVE | FUNCTIONAL RECOVERY | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | CT ANGIOGRAPHY | PROGNOSTIC VALUE | DIAGNOSTIC PERFORMANCE | INTRACORONARY THROMBUS | POSITRON-EMISSION-TOMOGRAPHY | HYPERINTENSE PLAQUE | CORONARY-ARTERY-DISEASE | Tomography, X-Ray Computed - methods | Reproducibility of Results | Magnetic Resonance Imaging, Cine - methods | Myocardial Ischemia - diagnosis | Humans | CT imaging | Medical colleges | Atherosclerosis | Chronic diseases | Development and progression | Myocardial ischemia | Heart attack | Heart | Medical imaging | Ischemia | Coronary vessels | Tomography | Cardiovascular disease | Acute coronary syndromes | Angina pectoris | Blood clots | Veins & arteries | CAC, coronary artery calcium | CTA, computed tomography angiography | FFR, fractional flow reserve | ACS, acute coronary syndrome | MI, myocardial infarction | LGE, late gadolinium enhancement | The Present and Future | SPECT, single-photon emission computed tomography | CMR, cardiac magnetic resonance
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2010, Volume 55, Issue 23, pp. 2527 - 2535
Inflammation is a determinant of atherosclerotic plaque rupture, the event leading to most myocardial infarctions and strokes. Although conventional imaging...
Cardiovascular | Internal Medicine | atherosclerosis | positron emission tomography | imaging | FDG-PET | HIGH-FAT | APOLIPOPROTEIN E-DEFICIENT | VASCULAR F-18-FDG UPTAKE | CARDIAC & CARDIOVASCULAR SYSTEMS | CAROTID ATHEROSCLEROSIS | RISK-FACTORS | LOW-CARBOHYDRATE | CORONARY-ARTERIES | INTRAPLAQUE HEMORRHAGE | VULNERABLE PLAQUE | Glucose metabolism | PET imaging | Atherosclerotic plaque | Inflammation | Glucose | Coronary heart disease | Dextrose | Medical colleges | Cardiovascular agents
Cardiovascular | Internal Medicine | atherosclerosis | positron emission tomography | imaging | FDG-PET | HIGH-FAT | APOLIPOPROTEIN E-DEFICIENT | VASCULAR F-18-FDG UPTAKE | CARDIAC & CARDIOVASCULAR SYSTEMS | CAROTID ATHEROSCLEROSIS | RISK-FACTORS | LOW-CARBOHYDRATE | CORONARY-ARTERIES | INTRAPLAQUE HEMORRHAGE | VULNERABLE PLAQUE | Glucose metabolism | PET imaging | Atherosclerotic plaque | Inflammation | Glucose | Coronary heart disease | Dextrose | Medical colleges | Cardiovascular agents
Journal Article
JACC: Cardiovascular Imaging, ISSN 1936-878X, 2017, Volume 11, Issue 1, pp. 94 - 107
Abstract Objectives The purpose of this study was to explore the diagnostic usefulness of hybrid cardiac magnetic resonance (CMR) and positron emission...
Cardiovascular | 18F-fluorodeoxyglucose | cardiac sarcoidosis | MR/PET | F-fluorodeoxyglucose | CARDIAC & CARDIOVASCULAR SYSTEMS | DISEASE | PET/CT | F-18-fluorodeoxyglucose | CMR | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Life Sciences | Bioengineering | Nuclear medicine | PET
Cardiovascular | 18F-fluorodeoxyglucose | cardiac sarcoidosis | MR/PET | F-fluorodeoxyglucose | CARDIAC & CARDIOVASCULAR SYSTEMS | DISEASE | PET/CT | F-18-fluorodeoxyglucose | CMR | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Life Sciences | Bioengineering | Nuclear medicine | PET
Journal Article
Atherosclerosis, ISSN 0021-9150, 2017, Volume 262, pp. 154 - 162
Abstract Background Cocaine, a powerful vasoconstrictor, induces immune responses including cytokine elevations. Chronic cocaine use is associated with...
Cardiovascular | Vascular disease | Endothelial dysfunction | Neurotoxicity | Cocaine | Cardiotoxicity | Atherosclerosis | C-REACTIVE PROTEIN | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | CHEST-PAIN | BLOOD-BRAIN-BARRIER | POSITRON-EMISSION-TOMOGRAPHY | DRUG-ADDICTION | MAGNETIC-RESONANCE | PERIPHERAL VASCULAR DISEASE | AFRICAN-AMERICANS | CRACK COCAINE | Vascular Diseases - prevention & control | Prognosis | Humans | Risk Factors | Cocaine-Related Disorders - therapy | Arteries - drug effects | Vascular Diseases - physiopathology | Arteries - pathology | Vascular Diseases - chemically induced | Vasoconstriction - drug effects | Vascular Diseases - mortality | Cocaine-Related Disorders - complications | Animals | Central Nervous System Stimulants - adverse effects | Cocaine-Related Disorders - mortality | Time Factors | Arteries - physiopathology | Cocaine - adverse effects | Hypertension | Drug abuse | Medical colleges | Care and treatment | Comorbidity | Development and progression | Substance abuse | Benzodiazepines | Preventive health services | Thromboembolism | Medicine, Preventive | Public health | Blood circulation disorders | Endothelium | Index Medicus
Cardiovascular | Vascular disease | Endothelial dysfunction | Neurotoxicity | Cocaine | Cardiotoxicity | Atherosclerosis | C-REACTIVE PROTEIN | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | CHEST-PAIN | BLOOD-BRAIN-BARRIER | POSITRON-EMISSION-TOMOGRAPHY | DRUG-ADDICTION | MAGNETIC-RESONANCE | PERIPHERAL VASCULAR DISEASE | AFRICAN-AMERICANS | CRACK COCAINE | Vascular Diseases - prevention & control | Prognosis | Humans | Risk Factors | Cocaine-Related Disorders - therapy | Arteries - drug effects | Vascular Diseases - physiopathology | Arteries - pathology | Vascular Diseases - chemically induced | Vasoconstriction - drug effects | Vascular Diseases - mortality | Cocaine-Related Disorders - complications | Animals | Central Nervous System Stimulants - adverse effects | Cocaine-Related Disorders - mortality | Time Factors | Arteries - physiopathology | Cocaine - adverse effects | Hypertension | Drug abuse | Medical colleges | Care and treatment | Comorbidity | Development and progression | Substance abuse | Benzodiazepines | Preventive health services | Thromboembolism | Medicine, Preventive | Public health | Blood circulation disorders | Endothelium | Index Medicus
Journal Article
JACC: Cardiovascular Imaging, ISSN 1936-878X, 2015, Volume 8, Issue 2, pp. 121 - 130
Abstract Objectives This study sought to determine whether splenic activation after acute coronary syndrome (ACS) is linked to leukocyte proinflammatory...
Cardiovascular | atherosclerosis | FDG | acute coronary syndrome | inflammation | spleen | events | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | HEART-FAILURE | ACUTE CORONARY SYNDROMES | PLAQUE | CELL LUNG-CANCER | POSITRON-EMISSION-TOMOGRAPHY | STATIN THERAPY | ACTIVATED MACROPHAGES | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Complications and side effects | Research | Splenic diseases | Cardiovascular diseases | Risk factors
Cardiovascular | atherosclerosis | FDG | acute coronary syndrome | inflammation | spleen | events | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | HEART-FAILURE | ACUTE CORONARY SYNDROMES | PLAQUE | CELL LUNG-CANCER | POSITRON-EMISSION-TOMOGRAPHY | STATIN THERAPY | ACTIVATED MACROPHAGES | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Complications and side effects | Research | Splenic diseases | Cardiovascular diseases | Risk factors
Journal Article
JACC: Cardiovascular Imaging, ISSN 1936-878X, 2016, Volume 9, Issue 3, pp. 306 - 316
Abstract Cardiac magnetic resonance offers the promise of radiation-free imaging of the coronary arteries, providing information with respect to luminal...
Cardiovascular | coronary artery disease | magnetic resonance imaging | PET/MRI | Key Words coronary artery disease | WALL THICKNESS | CARDIAC & CARDIOVASCULAR SYSTEMS | CARDIOVASCULAR MAGNETIC-RESONANCE | ATHEROSCLEROTIC CAROTID PLAQUE | HIGH-INTENSITY SIGNALS | COMPUTED-TOMOGRAPHY | CONTRAST AGENT | INTRACORONARY THROMBUS | IN-VIVO | HIGH-RESOLUTION | HYPERINTENSE PLAQUE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Coronary Stenosis - diagnostic imaging | Coronary Vessels - diagnostic imaging | Severity of Illness Index | Predictive Value of Tests | Coronary Artery Disease - diagnostic imaging | Coronary Artery Disease - therapy | Coronary Stenosis - therapy | Prognosis | Coronary Angiography - methods | Humans | Magnetic Resonance Angiography | Plaque, Atherosclerotic
Cardiovascular | coronary artery disease | magnetic resonance imaging | PET/MRI | Key Words coronary artery disease | WALL THICKNESS | CARDIAC & CARDIOVASCULAR SYSTEMS | CARDIOVASCULAR MAGNETIC-RESONANCE | ATHEROSCLEROTIC CAROTID PLAQUE | HIGH-INTENSITY SIGNALS | COMPUTED-TOMOGRAPHY | CONTRAST AGENT | INTRACORONARY THROMBUS | IN-VIVO | HIGH-RESOLUTION | HYPERINTENSE PLAQUE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Coronary Stenosis - diagnostic imaging | Coronary Vessels - diagnostic imaging | Severity of Illness Index | Predictive Value of Tests | Coronary Artery Disease - diagnostic imaging | Coronary Artery Disease - therapy | Coronary Stenosis - therapy | Prognosis | Coronary Angiography - methods | Humans | Magnetic Resonance Angiography | Plaque, Atherosclerotic
Journal Article