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Nature Neuroscience, ISSN 1097-6256, 03/2014, Volume 17, Issue 3, pp. 357 - 366
The microtubule-associated protein tau is involved in a number of neurodegenerative disorders, including Alzheimer's disease. Previous studies have linked... 
NEUROFIBRILLARY TANGLES | HUMAN GENOME | GENE | DROSOPHILA-MELANOGASTER | ALZHEIMERS-DISEASE | DNA-DAMAGE | IN-VIVO | PROTEIN BINDS | PIWI PROTEINS | CELL | NEUROSCIENCES | Chromatin | Physiological aspects | Nervous system | Degeneration | Research | Gene expression | Tau proteins | Index Medicus
Journal Article
Journal Article
Neuron, ISSN 0896-6273, 01/2018, Volume 97, Issue 1, p. 108
Journal Article
Neuron, ISSN 0896-6273, 08/2012, Volume 75, Issue 4, pp. 618 - 632
Mitochondrial abnormalities have been documented in Alzheimer’s disease and related neurodegenerative disorders, but the causal relationship between... 
ALZHEIMERS-DISEASE BRAIN | DOMINANT OPTIC ATROPHY | MITOCHONDRIAL-FUNCTION | MOUSE MODEL | LIGHT-CHAIN | FRONTOTEMPORAL DEMENTIA | AXONAL-TRANSPORT | NEUROSCIENCES | DYNAMIN-RELATED PROTEIN | PHOSPHORYLATION SITES | TRANSGENIC MICE | Neurons - pathology | Microtubule-Associated Proteins - genetics | Tauopathies - genetics | Cytoskeletal Proteins - genetics | Gelsolin - metabolism | Microtubule-Associated Proteins - metabolism | Humans | Actins - metabolism | Tauopathies - pathology | Cytoplasm - metabolism | MicroRNAs - metabolism | Green Fluorescent Proteins - genetics | Mitochondrial Proteins - genetics | Drosophila Proteins - metabolism | GTP-Binding Proteins - genetics | Nerve Degeneration - metabolism | Neurons - ultrastructure | tau Proteins - genetics | Cell Death - genetics | Mitochondria - genetics | Mitochondrial Proteins - metabolism | ATP Synthetase Complexes - metabolism | Cell Cycle Proteins - genetics | Tauopathies - complications | Cytoskeletal Proteins - metabolism | Myosins - metabolism | Cytoplasm - genetics | RNA Interference - physiology | Disease Models, Animal | In Situ Nick-End Labeling | Green Fluorescent Proteins - metabolism | Animals, Genetically Modified | Gene Expression Regulation - genetics | Drosophila | Cell Cycle Proteins - metabolism | Mitochondria - metabolism | Mitochondria - pathology | Mutation - genetics | Animals | GTP Phosphohydrolases - metabolism | Analysis of Variance | GTP Phosphohydrolases - genetics | Gelsolin - genetics | Mice | Drosophila Proteins - genetics | Nerve Degeneration - etiology | Voltage-Dependent Anion Channels - metabolism | GTP-Binding Proteins - metabolism | Nervous system diseases | Actin | Neurons | Utrophin | Myosin | Mitochondrial DNA | Alzheimer's disease | Proteins | Phosphorylation | Mitochondria | Neurotoxicity | Insects | Microscopy | Neurodegeneration | Pathogenesis | Morphology | Mutation | Defects | Index Medicus | Neurodegenerative diseases | Tau protein | Cell death | Elongation
Journal Article
New England Journal of Medicine, ISSN 0028-4793, 11/2004, Volume 351, Issue 19, pp. 1937 - 1940
Journal Article
Glia, ISSN 0894-1491, 10/2019, Volume 67, Issue 10, pp. 1933 - 1957
α‐Synucleinopathies are neurodegenerative diseases that are characterized pathologically by α‐synuclein inclusions in neurons and glia. The pathologic... 
Parkinson's disease | multiple system atrophy | glia | Drosophila | α‐Synuclein | Phenotypes | Dopamine | Transcription | Neurodegenerative diseases | Neurons | Inclusions | Synuclein | Neuronal-glial interactions | Neurological diseases | Atrophy | Insects | Autonomic nervous system | Neurodegeneration | Inclusion bodies | In vivo methods and tests | Dopamine receptors
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 01/2019, Volume 380, Issue 5, pp. 492 - 494
A recent study implicates the enzyme poly(adenosine 5′-diphosphate-ribose) polymerase 1 (PARP1) as a mediator of neuronal cell death in Parkinson’s disease.... 
Proteins | Adenosine | Poly(ADP-ribose) Polymerase 1 | Cell death | Ribose | DNA damage | Clinical trials | Biomarkers | Poly(ADP-ribose) polymerase | Drug development | Apoptosis | Dementia
Journal Article
American Journal of Pathology, The, ISSN 0002-9440, 2010, Volume 176, Issue 5, pp. 2058 - 2066
The pathologies of major neurodegenerative diseases including Parkinson disease and Alzheimer disease have been well known for decades. More recently, advances... 
Pathology | NEURONAL CEROID-LIPOFUSCINOSES | TAU TRANSGENIC MICE | HUMAN ALPHA-SYNUCLEIN | NEUROTOXICITY IN-VIVO | PAIRED HELICAL FILAMENTS | MUTANT HUNTINGTIN FRAGMENT | PATHOLOGY | INCLUSION-BODY FORMATION | GENOME-WIDE ASSOCIATION | CATHEPSIN-D DEFICIENCY | PARKINSONS-DISEASE | ASIP Outstanding Investigator Award Lecture
Journal Article
Neuron, ISSN 0896-6273, 01/2018, Volume 97, Issue 1, pp. 108 - 124.e6
Journal Article
The Journal of Neuroscience, ISSN 0270-6474, 11/2017, p. 1550
Journal Article