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The Journal of biological chemistry, ISSN 0021-9258, 06/2019, Volume 294, Issue 32, pp. jbc.RA119.009442 - 12090
Unlike most other tissues, the colon epithelium is exposed to high levels of H2S derived from gut microbial metabolism. H2S is a signaling molecule that... 
Index Medicus
Journal Article
Journal Article
Cancer Letters, ISSN 0304-3835, 12/2014, Volume 355, Issue 1, p. 1
  Mutations in theAPC(adenomatous polyposis coli) gene, which encodes a multi-functional protein with a well-defined role in the canonical Wnt pathway,... 
Proteins | Genes | Colorectal cancer | Conflicts of interest | Ligands | Mutation
Journal Article
Laboratory investigation; a journal of technical methods and pathology, ISSN 0023-6837, 05/2019
Somatic APC (adenomatous polyposis coli), TP53, KRAS mutations are present in roughly 80%, 60%, and 40%, respectively, of human colorectal cancers (CRCs). Most... 
Index Medicus
Journal Article
Cell Cycle, ISSN 1538-4101, 10/2011, Volume 10, Issue 20, pp. 3429 - 3429
Journal Article
Cancer Research, ISSN 0008-5472, 02/2017, Volume 77, Issue 3 Supplement, pp. PR07 - PR07
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 02/2019, Volume 37, Issue 4_suppl, pp. 595 - 595
Journal Article
The Journal of Pathology, ISSN 0022-3417, 09/2017, Volume 243, Issue 1, pp. 16 - 25
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. 2684 - 2684
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. 672 - 672
Inactivation of the APC (adenomatous polyposis coli) tumor suppressor gene plays an important role in initiating most adenomas and colorectal cancers (CRCs).... 
Journal Article
Oncotarget, 11/2017, Volume 8, Issue 55, pp. 94330 - 94344
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 08/2015, Volume 21, Issue 16 Supplement, pp. AS06 - AS06
Journal Article
Cell, ISSN 0092-8674, 2009, Volume 138, Issue 5, pp. 822 - 829
The identification and characterization of cancer stem cells might lead to more effective treatments for some cancers by focusing therapy on the most malignant... 
BREAST-CANCER | PROGENITOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE MODEL | RESISTANCE | MICE | ACUTE MYELOID-LEUKEMIA | DIFFERENTIATION | IDENTIFICATION | TUMOR-INITIATING CELLS | TRANSPLANTATION | CELL BIOLOGY | Neoplasms - therapy | Animals | Neoplasms - genetics | Neoplasms - immunology | Humans | Neoplastic Stem Cells - pathology | Clone Cells | Genetic research | Analysis | Stem cells | Cancer | Index Medicus
Journal Article
Molecular Cancer Research, ISSN 1541-7786, 04/2016, Volume 14, Issue 4 Supplement, pp. A21 - A21
Journal Article
PLoS Genetics, ISSN 1553-7390, 11/2015, Volume 11, Issue 11
  Adenomatous polyposis coli (APC) inactivating mutations are present in most human colorectal cancers and some other cancers. The APC protein regulates the... 
Rodents | Colorectal cancer | Mutation | Kinases | Tumors
Journal Article
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