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Journal of immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 9/2018, Volume 201, Issue 6, pp. 1633 - 1638
Igκ locus contraction and Vκ gene usage are controlled by Cer, a cis-acting sequence in the Vκ-Jκ intervening region. This effect is attributed to two CTCF... 
Journal Article
Journal of Immunology, ISSN 0022-1767, 09/2018, Volume 201, Issue 6, pp. 1633 - 1638
Journal Article
F1000Research, ISSN 2046-1402, 2019, Volume 8, p. 347
Vast repertoires of unique antigen receptors are created in developing lymphocytes. The antigen receptor loci contain many variable (V), diversity (D), and... 
Antigens | Chromatin | Immunoglobulins | J gene | Recombination | Transcription factors | Immunology | Molecular modelling | Lymphocytes | Exons | Gene expression | Conformation
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 09/2018, Volume 201, Issue 6, pp. 1633 - 1638
Ig kappa locus contraction and V kappa gene usage are controlled by Cer, a cis-acting sequence in the V kappa-J kappa intervening region. This effect is... 
LOCUS CONTRACTION | REPERTOIRE | HEAVY-CHAIN GENE | TRANSCRIPTION | V(D)J RECOMBINATION | IMMUNOGLOBULIN | ENHANCER | IMMUNOLOGY | BINDING | INTERVENING REGION | GENOME
Journal Article
细胞研究:英文版, ISSN 1001-0602, 2012, Volume 22, Issue 2, pp. 280 - 282
The CTCF/cohesin complex regu- lates higher order chromatin structure by creating long-range chromatin loops and by insulating neighboring genes from each... 
建筑师 | 染色质结构 | 重排 | 尖吻鲈 | 受体位点 | 淋巴细胞 | 黏合 | 结合位点
Journal Article
Current Opinion in Immunology, ISSN 0952-7915, 2012, Volume 24, Issue 2, pp. 129 - 131
Journal Article
Current Opinion in Immunology, ISSN 0952-7915, 04/2012, Volume 24, Issue 2, pp. 129 - 131
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 2014, Volume 5, p. 49
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 10/2012, Volume 109, Issue 42, pp. 17004 - 17009
Noncoding sense and antisense germ-line transcription within the Ig heavy chain locus precedes V(D)J recombination and has been proposed to be associated with... 
V(D)J rearrangement | Noncoding RNA | CTCF | Long-range interactions | Biological Sciences | noncoding RNA | long-range interactions
Journal Article
Frontiers in Immunology, 02/2014, Volume 5
At both the immunoglobulin (Ig) heavy and kappa light chain loci, there are >100 functional variable (V) genes spread over >2 Mb that must move into close... 
Chromatin | non-coding RNA | histone modification | V(D)J Recombination | antigen receptor | CTCF
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2012, Volume 109, Issue 50, pp. 20192 - 20193
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 1990, Volume 172, Issue 5, pp. 1377 - 1390
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2011, Volume 108, Issue 23, pp. 9566 - 9571
Journal Article
Seminars in Immunology, ISSN 1044-5323, 12/2010, Volume 22, Issue 6, p. 346
V(D)J recombination is a crucial component of the adaptive immune response, allowing for the production of a diverse antigen receptor repertoire (Ig and TCR).... 
Post-translational modification | Immunoglobulins | Chromatin | Lysine | DNA binding proteins
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 09/2018, Volume 9, p. 2074
To date there has not been a study directly comparing relative Ig kappa rearrangement frequencies obtained from genomic DNA (gDNA) and cDNA and since each... 
Pre-B cells | Enhancer | Pro-B cells | V(D)J recombination | Repertoire | Immunoglobulin | Next generation sequencing | RECOMBINATION | enhancer | immunoglobulin | HYPERSENSITIVE SITES | IMMUNOLOGY | INTERVENING REGION | pro-B cells | MAMMALIAN GENOMES | IMMUNOGLOBULIN LOCI | pre-B cells | MICE | repertoire | DIFFERENTIATION | CHROMATIN INTERACTIONS | EXPRESSION | Next Generation Sequencing
Journal Article
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