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PLoS ONE, ISSN 1932-6203, 02/2018, Volume 13, Issue 2, pp. e0193098 - e0193098
Forty percent of patients with diffuse large B-cell lymphoma (DLBCL) show resistant disease to standard chemotherapy (CHOP) in combination with the anti-CD20... 
WEE1 KINASE | PATHWAY | RITUXIMAB | MULTIDISCIPLINARY SCIENCES | IMPAIR ANTITUMOR-ACTIVITY | IBRUTINIB | RECEPTOR | CHOP | MONOCLONAL-ANTIBODY | INHIBITORS | EXPRESSION | Doxorubicin - therapeutic use | Protein-Tyrosine Kinases - metabolism | Humans | Male | Lymphoma, Large B-Cell, Diffuse - metabolism | Neoplasm Proteins - metabolism | Cyclophosphamide - therapeutic use | Protein-Tyrosine Kinases - genetics | Cell Cycle Proteins - genetics | Female | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Genome-Wide Association Study | Lymphoma, Large B-Cell, Diffuse - drug therapy | Lymphoma, Large B-Cell, Diffuse - pathology | Cell Cycle Proteins - metabolism | Nuclear Proteins - metabolism | Poly (ADP-Ribose) Polymerase-1 - metabolism | Antigens, CD20 - metabolism | Antigens, CD20 - genetics | Rituximab - pharmacology | Drug Resistance, Neoplasm - genetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Vincristine - therapeutic use | Cell Line, Tumor | Lymphoma, Large B-Cell, Diffuse - genetics | Poly (ADP-Ribose) Polymerase-1 - genetics | Prednisone - therapeutic use | Drug Resistance, Neoplasm - drug effects | Lymphomas | Drug therapy, Combination | Drug therapy | Patient outcomes | Methods | Drugs | Target recognition | Leukemia | Genes | Clinical trials | Association analysis | Oncology | Genomes | Biology | Kinases | Cancer therapies | Supervision | Medical research | Hematology | DNA probes | Rituximab | Principal components analysis | Gene expression | Lymphoma | Pathology | Poly(ADP-ribose) Polymerase 1 | Chemotherapy | Lymphocytes B | Medical prognosis | Cell lines | Quality control | Monoclonal antibodies | CD20 antigen | Mutation | Cancer | Apoptosis | B-cell lymphoma | Index Medicus
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 06/2019, Volume 25, Issue 12, pp. 3517 - 3527
Purpose: Biodistribution of bispecific antibodies in patients is largely unknown. We therefore performed a feasibility study in 9 patients with advanced... 
Journal Article
Cancer Research, ISSN 0008-5472, 04/2011, Volume 71, Issue 8 Supplement, pp. 2960 - 2960
Journal Article
by Pers, Tune H and Karjalainen, Juha M and Chan, Yingleong and Westra, Harm-Jan and Wood, Anew R and Yang, Jian and Lui, Julian C and Vedantam, Sailaja and Gustafsson, Stefan and Esko, Tonu and Frayling, Tim and Speliotes, Elizabeth K and Boehnke, Michael and Raychaudhuri, Soumya and Fehrmann, Rudolf S. N and Hirschhorn, Joel N and Franke, Lude and Chu, Auey Y and Estrada, Karol and Luan, Jian'an and Kutalik, Zoltán and Amin, Najaf and Buchkovich, Martin L and Croteau-Chonka, Damien C and Day, Felix R and Duan, Yanan and Fall, Tove and Fehrmann, Rudolf and Ferreira, Teresa and Jackson, Anne U and Karjalainen, Juha and Lo, Ken Sin and Locke, Adam E and Mägi, Reedik and Mihailov, Evelin and Porcu, Eleonora and Randall, Joshua C and Scherag, Ané and Vinkhuyzen, Anna A. E and Winkler, Thomas W and Workalemahu, Tsegaselassie and Zhao, Jing Hua and Absher, Devin and Albrecht, Eva and Anderson, Denise and Baron, Jeffrey and Beekman, Marian and Demirkan, Ayse and Ehret, Georg B and Feenstra, Bjarke and Feitosa, Mary F and Fischer, Krista and Fraser, Ross M and Goel, Anuj and Gong, Jian and Justice, E and Kanoni, Stavroula and Kleber, Marcus E and Kristiansson, Kati and Lim, Unhee and Lotay, Vaneet and Mangino, Massimo and Mateo Leach, Irene and Medina-Gomez, Carolina and Nalls, Michael A and Nyholt, Dale R and Palmer, Cameron D and Pasko, Dorota and Pechlivanis, Sonali and Prokopenko, Inga and Ried, Janina S and Ripke, Stephan and Shungin, Dmitry and Stancáková, Alena and Strawbridge, Rona J and Sung, Yun Ju and Tanaka, Toshiko and Teumer, Alexander and Trompet, Stella and van der Laan, Sander W and van Setten, Jessica and van Vliet-Ostaptchouk, Jana V and Wang, Zhaoming and Yengo, Loïc and Zhang, Weihua and Afzal, Uzma and Ärnlöv, Johan and Arscott, Gillian M and Bandinelli, Stefania and Barrett, Amy and Bellis, Claire and Bennett, Amanda J and Berne, Christian and Blüher, Matthias and Bolton, Jennifer L and Böttcher, Yvonne and Boyd, Heather A and Bruinenberg, Marcel and Buckley, Brendan M and Buyske, Steven and ... and Genetic Invest ANthropometric Trai and Genetic Investigation of ANthropometric Traits (GIANT) Consortium and Science for Life Laboratory, SciLifeLab and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Institutionen för medicinska vetenskaper and Molekylär epidemiologi
Nature communications, ISSN 2041-1723, 2015, Volume 6, Issue 1, pp. 5890 - 5890
The main challenge for gaining biological insights from genetic associations is identifying which genes and pathways explain the associations. Here we present... 
NETWORK | INTEGRATION | MULTIDISCIPLINARY SCIENCES | CANDIDATE GENES | DISEASE | ARCHITECTURE | COMMON | LOCI | IDENTIFICATION | HEIGHT | DATA SETS | Genome-Wide Association Study - methods | Software | Index Medicus | Medical and Health Sciences | Medicin och hälsovetenskap
Journal Article
by Anderson, Carl A and Boucher, Gabrielle and Lees, Charlie W and Franke, Ane and D'Amato, Mauro and Taylor, Kent D and Lee, James C and Goyette, Philippe and Imielinski, Marcin and Latiano, Anna and Lagacé, Caroline and Scott, Regan and Amininejad, Leila and Bumpstead, Suzannah and Baidoo, Leonard and Baldassano, Robert N and Barclay, Murray and Bayless, Theodore M and Brand, Stephan and Büning, Carsten and Colombel, Jean-Frédéric and Denson, Lee A and de Vos, Martine and Dubinsky, Marla and Edwards, Cathryn and Ellinghaus, David and Fehrmann, Rudolf S. N and Floyd, James A. B and Florin, Timothy and Franchimont, Denis and Franke, Lude and Georges, Michel and Glas, Jürgen and Glazer, Nicole L and Guthery, Stephen L and Haritunians, Talin and Hayward, Nicholas K and Hugot, Jean-Pierre and Jobin, Gilles and Laukens, Debby and Lawrance, Ian and Lémann, Marc and Levine, Arie and Libioulle, Cecile and Louis, Edouard and McGovern, Dermot P and Milla, Monica and Montgomery, Grant W and Morley, Katherine I and Mowat, Craig and Ng, Aylwin and Newman, William and Ophoff, Roel A and Papi, Laura and Palmieri, Orazio and Peyrin-Biroulet, Laurent and Panés, Julián and Phillips, Anne and Prescott, Natalie J and Proctor, Deborah D and Roberts, Rebecca and Russell, Richard and Rutgeerts, Paul and Sanderson, Jeremy and Sans, Miquel and Schumm, Philip and Seibold, Frank and Sharma, Yashoda and Simms, Lisa A and Seielstad, Mark and Steinhart, A. Hillary and Targan, Stephan R and van den Berg, Leonard H and Vatn, Morten and Verspaget, Hein and Walters, Thomas and Wijmenga, Cisca and Wilson, David C and Westra, Harm-Jan and Xavier, Ramnik J and Zhao, Zhen Z and Ponsioen, Cyriel Y and Andersen, Vibeke and Torkvist, Leif and Gazouli, Maria and Anagnou, Nicholas P and Karlsen, Tom H and Kupcinskas, Limas and Sventoraityte, Jurgita and Mansfield, John C and Kugathasan, Subra and Silverberg, Mark S and Halfvarson, Jonas and Rotter, Jerome I and Mathew, Christopher G and Griffiths, Anne M and Gearry, Richard and Ahmad, Tariq and Brant, Steven R and Chamaillard, Mathias and ... and Hälsoakademin and Örebro universitet
Nature genetics, ISSN 1061-4036, 2011, Volume 43, Issue 3, pp. 246 - 252
Journal Article
Nature Genetics, ISSN 1061-4036, 04/2010, Volume 42, Issue 4, pp. 295 - U42
Journal Article