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Immunity, ISSN 1074-7613, 09/2018, Volume 49, Issue 3, pp. 379 - 381
The pore-forming protein GSDMD promotes cytokine release and induces pyroptotic cell death. In this issue of , document how GSDMD triggers potassium efflux to... 
DNA | IMMUNOLOGY | Interferon | Bacterial infections | Biological response modifiers | Cell death | Efflux | Neutrophils | Infections | Punches | Kinases | Immunity | Proteins | Studies | Sensors | Potassium | Deoxyribonucleic acid--DNA | Viral infections | Pore formation | Apoptosis
Journal Article
Molecular Cell, ISSN 1097-2765, 06/2017, Volume 66, Issue 5, pp. 698 - 710.e5
TNF is an inflammatory cytokine that upon binding to its receptor, TNFR1, can drive cytokine production, cell survival, or cell death. TNFR1 stimulation causes... 
cytokine | caspase-8 | complex-II | p38 | cell death | MK2 | IAPs | RIPK1 | TNF | necroptosis | KINASE-ACTIVITY | SPATA2 LINKS CYLD | ACTIVATION | UBIQUITIN | INFLAMMATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALPHA-DEPENDENT APOPTOSIS | PROGRAMMED NECROSIS | NF-KAPPA-B | CANCER | SIGNALING COMPLEX | CELL BIOLOGY | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Phosphorylation | Apoptosis - drug effects | Humans | Multiprotein Complexes | Caspase 8 - metabolism | NF-kappa B - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Necrosis | Dose-Response Relationship, Drug | Transfection | Mitogen-Activated Protein Kinase 14 - metabolism | RNA Interference | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Mice, Inbred C57BL | Fas-Associated Death Domain Protein - metabolism | Protein-Serine-Threonine Kinases - genetics | MAP Kinase Kinase Kinases - metabolism | Mice, Knockout | HT29 Cells | Tumor Necrosis Factor-alpha - pharmacology | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Animals | Signal Transduction - drug effects | Medical research | Green buildings | Green design | RNA | Tumor necrosis factor | Cell death | Medicine, Experimental | Biochemistry | Research institutes | Genetic transcription | Genetic translation | Sustainable development
Journal Article
The EMBO Journal, ISSN 0261-4189, 09/2016, Volume 35, Issue 17, pp. 1848 - 1850
Journal Article
The EMBO Journal, ISSN 0261-4189, 09/2016, Volume 35, Issue 17, pp. 1848 - 1850
In this issue of The EMBO Journal, a multi‐layered global proteome resource, which comprehensively covers TNF‐induced phosphorylation and ubiquitination events... 
SPERMATOGENESIS | CYLD | PD1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | Enzymes | Phosphorylation | Proteomics | Apoptosis | Views | Immunology | Signal Transduction | Post-translational Modifications, Proteolysis & Proteomics
Journal Article
Clinical & Translational Immunology, ISSN 2050-0068, 01/2017, Volume 6, Issue 1, pp. e124 - n/a
Apoptosis is a caspase‐dependent programmed form of cell death, which is commonly believed to be an immunologically silent process, required for mammalian... 
NLRP3 INFLAMMASOME ACTIVATION | PROGRAMMED NECROSIS | C-FLIP | RECEPTOR-INDUCED APOPTOSIS | MODIFYING ENZYME A20 | MEDIATED APOPTOSIS | IMMUNOLOGY | NECROPTOTIC CELL-DEATH | NF-KAPPA-B | HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS | A20 RESTRICTS UBIQUITINATION | Transcription | Cell death | Gene regulation | Caspase | Tumor necrosis factor-TNF | Inflammation | Mutation | Kinases | Apoptosis
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 2018, Volume 26, Issue 5, pp. 877 - 889
RIPK1 is an essential downstream component of many pattern recognition and death receptors. RIPK1 can promote the activation of caspase-8 induced apoptosis and... 
NECROSIS-FACTOR RECEPTOR | ACTIVATION | HOMEOSTASIS | NECROPTOSIS | INHIBITION | PHOSPHORYLATION | INFLAMMATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CASPASE-8 | FADD | CELL-DEATH | CELL BIOLOGY | Tumor necrosis factor receptors | Neonates | Splenomegaly | Caspase | c-FLIP protein | Lethality | Pattern recognition | Thymus | FADD protein | Caspase-8 | Clonal deletion | Intestine | Cell death | Death receptors | Apoptosis
Journal Article
Circulation Research, ISSN 0009-7330, 08/2019, Volume 125, Issue Suppl_1
Journal Article
Cell Reports, ISSN 2211-1247, 07/2017, Volume 20, Issue 3, pp. 668 - 682
Journal Article
Molecular Cell, ISSN 1097-2765, 12/2009, Volume 36, Issue 5, pp. 831 - 844
Journal Article