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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2016, Volume 113, Issue 8, p. 2206
  The functional maturation and preservation of hepatic cells derived from human induced pluripotent stem cells (hiPSCs) are essential to personalized in vitro... 
Bioengineering | Genotype & phenotype | Biomimetics | Cellular biology | Stem cells | Gene expression | 3-D printers
Journal Article
Gastroenterology, ISSN 0016-5085, 2012, Volume 142, Issue 7, pp. 1547 - 1558.e14
Background & Aims Hepatocellular carcinoma (HCC) is believed to arise from tumor-initiating cells (T-ICs), although little is known about their stem cell–like... 
Gastroenterology and Hepatology | Self-Renewal | Liver Cancer | Response to Chemotherapy | Cancer Stem Cell
Journal Article
Hepatology, ISSN 0270-9139, 05/2019, Volume 69, Issue 5, pp. 2196 - 2213
Autophagy is important for hepatic homeostasis, nutrient regeneration, and organelle quality control. We investigated the mechanisms by which liver injury... 
BILE-ACID | FXR | OXIDATIVE STRESS | NRF2 | SALT EXPORT PUMP | LIVER | MICE | IDENTIFICATION | GASTROENTEROLOGY & HEPATOLOGY | NUCLEAR FACTOR-E2-RELATED FACTOR-2 | P-GLYCOPROTEIN | Taurocholic acid | Bile acids | Genes | Liver | Gallbladder diseases | Homeostasis | Autophagy | Bile duct | Clonal deletion | Quality control | Intracellular | Cholestasis | Phagocytosis | Bile
Journal Article
FASEB Journal, ISSN 0892-6638, 2017, Volume 31, Issue 12, pp. 5530 - 5542
Ourprevious studies have found that Growth factor receptor-bound protein2-associated binding protein 2 (Gab2)-a docking protein-governs the development of... 
Jak2/Stat3 signaling pathway | HCC | IL-6 | Therapeutic target | Knockout mouse | BIOCHEMISTRY & MOLECULAR BIOLOGY | therapeutic target | OVARIAN-CANCER | CELL BIOLOGY | LIVER-CANCER | OVEREXPRESSION | GROWTH | BIOLOGY | FATTY LIVER | GRB2-ASSOCIATED BINDER 2 | SCAFFOLDING ADAPTER | EXPRESSION | PROMOTES | knockout mouse | MAMMARY EPITHELIAL-CELLS | Diethylnitrosamine - toxicity | Carcinoma, Hepatocellular - chemically induced | Apoptosis - drug effects | Humans | Liver Neoplasms - chemically induced | Carcinoma, Hepatocellular - genetics | Tumor Cells, Cultured | Gene Expression Regulation, Neoplastic - physiology | Gene Expression Regulation, Neoplastic - genetics | Enzyme-Linked Immunosorbent Assay | Liver Neoplasms - genetics | Mice, Inbred C57BL | Signal Transduction - genetics | Blotting, Western | Hep G2 Cells | Xenograft Model Antitumor Assays | Cell Movement - drug effects | Animals | Mice, Nude | Adaptor Proteins, Signal Transducing - genetics | Liver Neoplasms - metabolism | Signal Transduction - physiology | Mice | Adaptor Proteins, Signal Transducing - metabolism | Carcinoma, Hepatocellular - metabolism | Cell proliferation | Phosphorylation | Bcl-2 protein | Transcription | Leukocyte migration | Liver | c-Myc protein | Hepatocellular carcinoma | AKT protein | Matrix metalloproteinase | Cyclin D1 | Kinases | Carcinogenesis | Interleukin 6 | Proteins | Signal transduction | Carcinogens | Fatty liver | Pathways | Clonal deletion | Diethylnitrosamine | Rodents | Janus kinase 2 | Deletion | Docking | Liver diseases | Extracellular signal-regulated kinase | Inflammation | Protein kinase inhibitors | Gene expression | Lymphoma | Signaling | Lymphocytes B | Cell migration | Matrilysin | B-cell lymphoma | Index Medicus | Stat3 signaling pathway | Research | Jak2
Journal Article
Journal Article
Biology of Reproduction, ISSN 0006-3363, 08/2012, Volume 87, Issue Suppl_1, pp. 91 - 91
Journal Article
International Journal of Photoenergy, ISSN 1110-662X, 2014, Volume 2014, pp. 1 - 14
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2015, Volume 112, Issue 43, p. 13342
  Previous data suggested a negative role of phosphatase and tensin homolog (Pten) and a positive function of SH2-containing tyrosine phosphatase (Shp2)/Ptpn11... 
Proteins | Genotype & phenotype | Anemia | Rodents | Erythrocytes | Genetics | Phosphatase
Journal Article
Spine, ISSN 0362-2436, 10/2013, Volume 38, Issue 21, pp. E1307 - E1312
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 10/2015, Volume 112, Issue 43, pp. 13342 - 13342
Previous data suggested a negative role of phosphatase and tensin homolog (Pten) and a positive function of SH2-containing tyrosine phosphatase (Shp2)/Ptpn11... 
Journal Article
Genes and Development, ISSN 0890-9369, 07/2012, Volume 26, Issue 14, pp. 1587 - 1601
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2013, Volume 110, Issue 8, p. 3137
  Overproduction of nitric oxide (NO) can cause neuronal damage, contributing to the pathogenesis of several neurodegenerative diseases and stroke (i.e., focal... 
Proteins | Stroke | Nitric oxide | Amino acids | Enzyme kinetics | Binding sites | Cells
Journal Article
Cancer Discovery, ISSN 2159-8274, 2014, Volume 4, Issue 6, pp. 640 - 641
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 11/2016, Volume 231, Issue 11, pp. 2529 - 2540
Journal Article