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PLoS ONE, ISSN 1932-6203, 07/2014, Volume 9, Issue 7, pp. e102847 - e102847
The extranuclear estrogen receptor pathway opens up novel perspectives in many physiological and pathological processes, especially in breast carcinogenesis.... 
CELLS | PROTEIN | SOLID TUMORS | PHOSPHORYLATION | MEMBRANE | MULTIDISCIPLINARY SCIENCES | GROWTH | KINASE | PTPN11 MUTATIONS | PROMOTES | ACTIVATING MUTATIONS | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - metabolism | Phosphorylation | Receptors, Estrogen - metabolism | Estrogens - pharmacology | Humans | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - antagonists & inhibitors | Rats | Mice, Transgenic | Mammary Neoplasms, Experimental - metabolism | Breast - metabolism | Rats, Sprague-Dawley | Breast Neoplasms - metabolism | Hydrazones - pharmacology | Benzenesulfonates - pharmacology | Animals | Cell Line, Tumor | Female | Cell Proliferation - drug effects | Mice | Estrogens - metabolism | Estradiol - pharmacology | Transcription | Disease | Trefoil factor | Estrogens | Estrogen | Estrogen receptors | AKT protein | Insulin-like growth factors | Metastasis | Kinases | Cyclin D1 | Phosphatase | Carcinogenesis | Estradiol | Critical components | Signal transduction | Carcinogens | Biological effects | Cell growth | Rodents | Tumorigenesis | Mammary gland | Growth factors | Pharmaceutical sciences | Deoxyribonucleic acid--DNA | Tyrosine | Anthracene | Transgenic mice | Extracellular signal-regulated kinase | siRNA | Breast cancer | Tumor cell lines | Metabolism | DNA biosynthesis | Sex hormones | Pathology | Signaling | Cell lines | Stem cells | Breast | 9,10-Dimethyl-1,2-benzanthracene | Adapter proteins | Tumors | Protein-tyrosine-phosphatase | Cancer | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 01/2013, Volume 110, Issue 1, pp. E79 - E88
The molecular mechanism underlying adipogenesis and the physiological functions of adipose tissue are not fully understood. We describe here a unique mouse... 
Preadipocyte | Transduction | Dephosphorylation | Substrate trapping | ACTIVATED PROTEIN-KINASE | RECEPTOR-GAMMA | transduction | MULTIDISCIPLINARY SCIENCES | substrate trapping | preadipocyte | ENERGY-BALANCE | 3T3-L1 ADIPOGENESIS | HEMATOPOIETIC-CELL DEVELOPMENT | INSULIN-RESISTANCE | dephosphorylation | MISSENSE MUTATION | ADIPOCYTE DIFFERENTIATION | PPAR-GAMMA | HYPOCALORIC DIET | Protein Kinases - metabolism | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - metabolism | DNA Primers - genetics | E1A-Associated p300 Protein - metabolism | Signal Transduction - genetics | PPAR gamma - metabolism | Adipogenesis - physiology | Mice, Knockout | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - physiology | Animals | Gene Deletion | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Leptin - administration & dosage | Signal Transduction - physiology | Blood Pressure - drug effects | Leptin - pharmacology | Lipodystrophy - physiopathology | Mice | p38 Mitogen-Activated Protein Kinases - metabolism | Adipose Tissue - transplantation | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - genetics | Leptin - deficiency | Real-Time Polymerase Chain Reaction | Disease Models, Animal | Physiology | Biochemistry | Body fat | Kinases | Gene expression | Rodents | Index Medicus | Biological Sciences | PNAS Plus
Journal Article
Journal Article
Journal Article
Journal Article
Development, ISSN 0950-1991, 01/2008, Volume 135, Issue 2, pp. 301 - 310
Journal Article
Oncotarget, ISSN 1949-2553, 2016, Volume 7, Issue 40, pp. 65676 - 65695
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 04/2011, Volume 15, Issue 4, pp. 763 - 772
Journal Article
Food Chemistry, ISSN 0308-8146, 04/2014, Volume 149, pp. 137 - 143
Journal Article
Journal Article
Cell Communication and Signaling, ISSN 1478-811X, 02/2014, Volume 12, Issue 1, pp. 10 - 10
BACKGROUND: In a classic model, Giα proteins including Gi1α, Gi2α and Gi3α are important for transducing signals from Giα protein-coupled receptors (GiαPCRs)... 
Shp2 | ERK1/2 | EGF | Gab1 | and breast cancer | receptor tyrosine kinase (RTK) | Akt | mTORC1 | EGFR
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 01/2014, Volume 5, Issue 1, pp. 61 - 64
Influenza is a global human health threat, and there is an immediate need for new antiviral therapies to circumvent the limitations of vaccination and current... 
endonuclease | Antiviral | influenza A | virtual screening | pharmacophore | CHEMISTRY, MEDICINAL | CONFORMER GENERATION | VIRUS | RESISTANCE
Journal Article