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Cell Death and Disease, ISSN 2041-4889, 04/2019, Volume 10, Issue 4, pp. 258 - 11
... suppresses the pathogenic immune response to dietary antigens in cystic fibrosis Valeria R. Villella1, Speranza Esposito1, Eleonora Ferrari1,2, Romina Monzani1,2... 
CYSTEAMINE | GLIADIN | ACTIVATION | AUTOIMMUNITY | INFLAMMATION | TRIGGERS | EPITHELIAL STRESS | TISSUE TRANSGLUTAMINASE | T-CELLS | CELIAC-DISEASE | CELL BIOLOGY | Cysteamine - pharmacology | Epithelial Cells - metabolism | Peptide Fragments - toxicity | Epithelial Cells - drug effects | GTP-Binding Proteins - antagonists & inhibitors | Humans | Autophagy - drug effects | Gliadin - toxicity | Cystic Fibrosis - immunology | Peptide Fragments - immunology | Autophagy - genetics | Transglutaminases - antagonists & inhibitors | Caco-2 Cells | Cystic Fibrosis Transmembrane Conductance Regulator - antagonists & inhibitors | Cytokines - metabolism | Gliadin - immunology | Mice, Inbred C57BL | Cystic Fibrosis Transmembrane Conductance Regulator - metabolism | Mice, Knockout | Homozygote | Animals | Cysteamine - therapeutic use | Cystic Fibrosis - genetics | Epithelial Cells - immunology | Transglutaminases - metabolism | Beclin-1 - genetics | Cystic Fibrosis Transmembrane Conductance Regulator - genetics | Heterozygote | Mice | Beclin-1 - metabolism | GTP-Binding Proteins - metabolism | Antigens | Immune response | Mucosa | Cystic fibrosis | Autoantigens | Inflammation | Autophagy | Transglutaminase 2 | Celiac disease | Transfection | Intestine | Gliadin | Conductance | Gluten | Phagocytosis | Cellular stress response | Life Sciences | Cellular Biology | Immunology
Journal Article
The lancet oncology, ISSN 1470-2045, 2017, Volume 18, Issue 6, pp. 812 - 822
Summary Background Previous trials from our group suggested an overall survival benefit with five cycles of adjuvant full-dose epirubicin plus ifosfamide in... 
Hematology, Oncology and Palliative Medicine | SURVIVAL | CRITERIA | THERAPY | RECIST | CLINICAL-TRIAL | HIGH-GRADE | ONCOLOGY | DOSE ADJUVANT CHEMOTHERAPY | EXTREMITIES | TUMOR RESPONSE ASSESSMENT | IFOSFAMIDE | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Epirubicin - administration & dosage | Trabectedin | Sarcoma - therapy | Young Adult | Neurilemmoma - therapy | Dioxoles - administration & dosage | Back | Adult | Neutropenia - chemically induced | Child | Extremities | Soft Tissue Neoplasms - therapy | Dacarbazine - administration & dosage | Thoracic Wall | Sarcoma, Synovial - therapy | Deoxycytidine - administration & dosage | Risk Factors | Docetaxel | Anemia - chemically induced | Etoposide - administration & dosage | Tetrahydroisoquinolines - administration & dosage | Thrombocytopenia - chemically induced | Abdominal Wall | Sarcoma - pathology | Leiomyosarcoma - therapy | Disease-Free Survival | Taxoids - administration & dosage | Ifosfamide - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Chemotherapy, Adjuvant - methods | Neoadjuvant Therapy - methods | Adolescent | Soft Tissue Neoplasms - pathology | Aged | Deoxycytidine - analogs & derivatives | Liposarcoma, Myxoid - therapy | Care and treatment | Anthracyclines | Sarcoma | Adjuvant treatment | Clinical trials | Product development | Standards | Cancer
Journal Article
The EMBO journal, ISSN 1460-2075, 2018, Volume 38, Issue 2, p. n/a
Intestinal handling of dietary proteins usually prevents local inflammatory and immune responses and promotes oral tolerance. However, in ~ 1% of the world... 
celiac disease | mucosal immunology | CFTR | gliadin | P31–43 peptide | OXIDATIVE STRESS | PROTEIN | CFTR FUNCTION | DIETARY ANTIGENS | BIOCHEMISTRY & MOLECULAR BIOLOGY | P31-43 peptide | INTESTINAL EPITHELIAL-CELLS | CELL BIOLOGY | CYTOKINE PRODUCTION | GLIADIN PEPTIDES | INFLAMMATION | TISSUE TRANSGLUTAMINASE | T-CELLS | Humans | Male | Peptide Fragments - pharmacology | Quinolones - pharmacology | Aminophenols - pharmacology | Young Adult | Protein Binding - drug effects | Protein Domains | Female | Child | Disease Models, Animal | Caco-2 Cells | Cell Line | Celiac Disease - genetics | Down-Regulation | Celiac Disease - drug therapy | Cystic Fibrosis Transmembrane Conductance Regulator - metabolism | Cystic Fibrosis Transmembrane Conductance Regulator - chemistry | Quinolones - administration & dosage | Animals | Adolescent | Cystic Fibrosis Transmembrane Conductance Regulator - genetics | Protein Conformation | Mice | Gliadin - pharmacology | Aminophenols - administration & dosage | Celiac Disease - metabolism | Cereals | Peptides | Epithelial cells | Mucosa | Lymphocytes T | Activation | Antibody response | Proteins | Anions | Intestine | Gliadin | Ion channels | Inhibition | Gluten | Immune system | Binding | Translocation | Immune response | Channel gating | Therapeutic applications | World population | Cystic fibrosis | Inflammation | Immunological tolerance | Transglutaminase 2 | Nuclear transport | Environmental stress | Resistance | Celiac disease | Intolerance | Diet | Fibrosis | Cytoskeleton | Conductance | Histocompatibility antigen HLA | Autoimmune diseases | Wheat | Dismantling | Adenosine triphosphatase | Immunology | Membrane & Intracellular Transport | Molecular Biology of Disease
Journal Article
Cell Death and Disease, ISSN 2041-4889, 01/2017, Volume 8, Issue 1, pp. e2544 - e2544
Journal Article
EMBO reports, ISSN 1469-3178, 2018, Volume 19, Issue 7, p. n/a
Journal Article
American Journal of Kidney Diseases, ISSN 0272-6386, 2010, Volume 56, Issue 4, pp. 670 - 685
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1211 - 13
... in zebrafish highlights the role of the SNARE protein Snap29 in neuromotor and epidermal development Valeria Mastrodonato1,3, Galina Beznoussenko1, Alexandre Mironov1... 
CONSERVATION | BIOGENESIS | BDNF | VESICLES | MULTIDISCIPLINARY SCIENCES | MOTOR | TRAFFICKING | PHENOTYPE | DISORDERS | AUTOPHAGY | SYNTAXIN 17 | Membrane fusion | Pathogenesis | SNAP receptors | Neuropathy | Neurodevelopmental disorders | Organelles | Autophagy | Ichthyosis | Membrane proteins | Mutants | Mitochondria | Microencephaly | Life span | Trigeminal nerve | Cell death | Genetic analysis | Cerebrum | SNAP-25 protein | Phagocytosis | Apoptosis
Journal Article
Physical review letters, ISSN 1079-7114, 2019, Volume 123, Issue 14
Using a Bayesian approach, we combine measurements of neutron star macroscopic observables obtained by astrophysical and gravitational observations to derive... 
PHYSICS, MULTIDISCIPLINARY | MATTER | MASSES | Neutron stars | Equations of state | Deformation | X ray binaries | Binary stars | Neutrons | Conditional probability | Parameterization | Bayesian analysis | X ray stars | Deposition
Journal Article
by Forouzanfar, Mohammad H and Biryukov, Stan and Brauer, Michael and Casey, Daniel and Delwiche, Kristen and Frostad, Joseph J and KC, Astha and Kyu, Hmwe H and Slepak, Erica Leigh and Thomas, Bernadette A and Wagner, Joseph and Aasvang, Gunn Marit and Abbafati, Cristiana and Aboyans, Victor and Abraham, Biju and Abraham, Jerry Puthenpurakal and Abu-Rmeileh, Niveen M E and Aburto, Tania C and Achoki, Tom and Adelekan, Ademola and Adofo, Koranteng and Adou, Arsène K and Adsuar, José C and Agardh, Emilie E and Al Lami, Faris H and Alam, Sayed Saidul and Alasfoor, Deena and Albittar, Mohammed I and Alegretti, Miguel A and Alfonso-Cristancho, Rafael and Alhabib, Samia and Ali, Raghib and Ali, Mohammed K and Alla, François and Allebeck, Peter and Allen, Peter J and Alsharif, Ubai and Alvarez, Elena and Alvis-Guzman, Nelson and Amankwaa, Adansi A and Ameh, Emmanuel A and Ameli, Omid and Amini, Heresh and Ammar, Walid and Anderson, Benjamin O and Antonio, Carl Abelardo T and Cunningham, Solveig Argeseanu and Arnlöv, Johan and Arsenijevic, Valentina S Arsic and Artaman, Al and Asghar, Rana J and Assadi, Reza and Atkins, Lydia S and Atkinson, Charles and Avila, Marco A and Awuah, Baffour and Bahit, Maria C and Bakfalouni, Talal and Banerjee, Amitava and Barregard, Lars and Barrero, Lope H and Barrientos-Gutierrez, Tonatiuh and Basto-Abreu, Ana C and Basu, Arindam and Basu, Sanjay and Basulaiman, Mohammed O and Beardsley, Justin and Bedi, Neeraj and Bell, Michelle L and Benjet, Corina and Bennett, Derrick A and Benzian, Habib and Bernabé, Eduardo and Beyene, Tariku J and Bhalla, Ashish and Bhutta, Zulfiqar A and Bikbov, Boris and Abdulhak, Aref A Bin and Blore, Jed D and Blyth, Fiona M and Bohensky, Megan A and Başara, Berrak Bora and Borges, Guilherme and Bose, Dipan and Boufous, Soufiane and Bourne, Rupert R and Brainin, Michael and Breitborde, Nicholas J and Brenner, Hermann and Briggs, Adam D M and Brooks, Peter M and Bruce, Nigel G and Brugha, Traolach S and Bukhman, Gene and Bulloch, Andrew G and Burney, Peter G J and Campuzano, Julio C and Cantoral, Alejandra J and Caravanos, Jack and Cárdenas, Rosario and ... and GBD 2013 Risk Factors Collaborators and GBD 2013 Risk Factors and Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa and Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa, enheten för hälsometri and Göteborgs universitet and Gothenburg University and Institute of Medicine, School of Public Health and Community Medicine and Sahlgrenska Academy and Sahlgrenska akademin and Institute of Medicine, Department of Public Health and Community Medicine, Health Metrics
The Lancet (British edition), ISSN 0140-6736, 2015, Volume 386, Issue 10010, pp. 2287 - 2323
Summary Background The Global Burden of Disease, Injuries, and Risk Factor study 2013 (GBD 2013) is the first of a series of annual updates of the GBD. Risk... 
Internal Medicine | ALL-CAUSE MORTALITY | TOBACCO SMOKING | MEDICINE, GENERAL & INTERNAL | AIR-POLLUTION | LONG-TERM EXPOSURE | CARDIOVASCULAR-DISEASE | BODY-MASS INDEX | CORONARY-HEART-DISEASE | FINE PARTICULATE MATTER | HOUSEHOLD COOKING | BLOOD-PRESSURE | Risk Assessment - methods | Occupational Exposure - adverse effects | Humans | Risk Factors | Metabolic Diseases - epidemiology | Male | Health Behavior | Sanitation - trends | Environmental Exposure - adverse effects | Global Health - trends | Global Health - statistics & numerical data | Female | Nutritional Status | Occupational Diseases - epidemiology | Medicine, Experimental | Medical research | Comparative analysis | Risk assessment | Outdoor air quality | Disease prevention | Comparative studies | Health risk assessment | Metabolism | Risk exposure | Risk factors | Age groups | Malalties | Risk factors in diseases | Factors de risc en les malalties | Diseases | Occupational Diseases | Risk Assessment | Global Health | Occupational Exposure | Sanitation | Metabolic Diseases | Environmental Exposure | Life Sciences | Santé publique et épidémiologie | methods | Hälsovetenskaper | epidemiology | statistics & numerical data | adverse effects | trends | Health Sciences | Nutrition and Disease | HNE Nutrition and Disease | Chair Nutrition and Disease | Voeding en Ziekte | VLAG | HNE Voeding en Ziekte
Journal Article