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Science, ISSN 0036-8075, 12/2016, Volume 354, Issue 6319, pp. aaf6814 - aaf6814
Journal Article
Genetics in Medicine, ISSN 1098-3600, 09/2016, Volume 18, Issue 9, pp. 906 - 913
Purpose: Geisinger Health System (GHS) provides an ideal platform for Precision Medicine. Key elements are the integrated health system, stable patient... 
genetic association | genomics | electronic health records | biobank | COMMON VARIANTS | TCF7L2 | ASSOCIATION ANALYSIS | FTO GENE | RISK | MC4R | OBESITY | REPLICATION | GENETICS & HEREDITY | WEIGHT | CONFERS | Phenotype | Public Health | Biological Specimen Banks | Humans | Biomedical Research | Genotype | Electronic Health Records | Precision Medicine | Index Medicus
Journal Article
by Gusarova, Viktoria and O'Dushlaine, Colm and Teslovich, Tanya M and Benotti, Peter N and Mirshahi, Tooraj and Gottesman, Omri and Van Hout, Cristopher V and Murray, Michael F and Mahajan, Anubha and Nielsen, Jonas B and Fritsche, Lars and Wulff, Anders Berg and Gudbjartsson, Daniel F and Sjögren, Marketa and Emdin, Connor A and Scott, Robert A and Lee, Wen-Jane and Small, Aeron and Kwee, Lydia C and Dwivedi, Om Prakash and Prasad, Rashmi B and Bruse, Shannon and Lopez, Alexander E and Penn, John and Marcketta, Anthony and Leader, Joseph B and Still, Christopher D and Kirchner, H. Lester and Mirshahi, Uyenlinh L and Wardeh, Amr H and Hartle, Cassandra M and Habegger, Lukas and Fetterolf, Samantha N and Tusie-Luna, Teresa and Morris, Andrew P and Holm, Hilma and Steinthorsdottir, Valgerdur and Sulem, Patrick and Thorsteinsdottir, Unnur and Rotter, Jerome I and Chuang, Lee-Ming and Damrauer, Scott and Birtwell, David and Brummett, Chad M and Khera, Amit V and Natarajan, Pradeep and Orho-Melander, Marju and Flannick, Jason and Lotta, Luca A and Willer, Cristen J and Holmen, Oddgeir L and Ritchie, Marylyn D and Ledbetter, David H and Murphy, Andrew J and Borecki, Ingrid B and Reid, Jeffrey G and Overton, John D and Hansson, Ola and Groop, Leif and Shah, Svati H and Kraus, William E and Rader, Daniel J and Chen, Yii-Der I and Hveem, Kristian and Wareham, Nicholas J and Kathiresan, Sekar and Melander, Olle and Stefansson, Kari and Nordestgaard, Børge G and Tybjærg-Hansen, Anne and Abecasis, Goncalo R and Altshuler, David and Florez, Jose C and Boehnke, Michael and McCarthy, Mark I and Yancopoulos, George D and Carey, David J and Shuldiner, Alan R and Baras, Aris and Dewey, Frederick E and Gromada, Jesper and Diabetes - Cardiovascular Disease and Kardiovaskulär forskning - hypertoni and Cardiovascular Research - Hypertension and Diabetes - kardiovaskulär sjukdom and Lund University and Genomics, Diabetes and Endocrinology and EpiHealth: Epidemiology for Health and Genomik, diabetes och endokrinologi and Institutionen för kliniska vetenskaper, Malmö and Lunds universitet and Department of Clinical Sciences, Malmö
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2252 - 11
Angiopoietin-like 4 (ANGPTL4) is an endogenous inhibitor of lipoprotein lipase that modulates lipid levels, coronary atherosclerosis risk, and nutrient... 
HEART-DISEASE | REMNANT CHOLESTEROL | PLASMA-LIPIDS | MULTIDISCIPLINARY SCIENCES | MICE | ANGIOPOIETIN-LIKE PROTEIN-4 | LIPOPROTEIN-LIPASE | HAN CHINESE | CHINESE POPULATION | GENOME-WIDE ASSOCIATION | ADIPOSE-TISSUE | Diabetes Mellitus, Type 2 - genetics | Humans | Homeostasis | Male | Diabetes Mellitus, Type 2 - metabolism | Case-Control Studies | Genetic Variation | Diabetes Mellitus, Type 2 - etiology | Female | Lipoprotein Lipase - metabolism | Genetic Association Studies | Mice, Inbred C57BL | Risk Factors | Gene Silencing | Angiopoietin-like 4 Protein - deficiency | Mice, Knockout | Whole Exome Sequencing | Animals | Insulin Resistance - genetics | Angiopoietin-like 4 Protein - metabolism | Heterozygote | Mice | Blood Glucose - metabolism | Amino Acid Substitution | Angiopoietin-like 4 Protein - genetics | Deactivation | Angiopoietin | Diabetes mellitus | Health risks | Risk reduction | Risk | Lipoprotein lipase | Glucose | Lipase | Inactivation | Insulin | Proteins | Confidence intervals | Sensitivity | Nutrient loss | Rodents | Arteriosclerosis | Atherosclerosis | Genetics | Diabetes | Diabetes mellitus (non-insulin dependent) | Index Medicus | Medicinsk genetik | Basic Medicine | Medical Genetics | Clinical Medicine | Medical and Health Sciences | Endokrinologi och diabetes | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Klinisk medicin | Endocrinology and Diabetes
Journal Article
by Gusarova, Viktoria and O'Dushlaine, Colm and Teslovich, Tanya M and Benotti, Peter N and Mirshahi, Tooraj and Gottesman, Omri and Van Hout, Cristopher V and Murray, Michael F and Mahajan, Anubha and Nielsen, Jonas B and Fritsche, Lars and Wulff, Anders Berg and Gudbjartsson, Daniel F and Sjögren, Marketa and Emdin, Connor A and Scott, Robert A and Lee, Wen-Jane and Small, Aeron and Kwee, Lydia C and Dwivedi, Om Prakash and Prasad, Rashmi B and Bruse, Shannon and Lopez, Alexander E and Penn, John and Marcketta, Anthony and Leader, Joseph B and Still, Christopher D and Kirchner, H Lester and Mirshahi, Uyenlinh L and Wardeh, Amr H and Hartle, Cassandra M and Habegger, Lukas and Fetterolf, Samantha N and Tusie-Luna, Teresa and Morris, Andrew P and Holm, Hilma and Steinthorsdottir, Valgerdur and Sulem, Patrick and Thorsteinsdottir, Unnur and Rotter, Jerome I and Chuang, Lee-Ming and Damrauer, Scott and Birtwell, David and Brummett, Chad M and Khera, Amit V and Natarajan, Pradeep and Orho-Melander, Marju and Flannick, Jason and Lotta, Luca Andrea and Willer, Cristen J and Holmen, Oddgeir L and Ritchie, Marylyn D and Ledbetter, David H and Murphy, Andrew J and Borecki, Ingrid B and Reid, Jeffrey G and Overton, John D and Hansson, Ola and Groop, Leif and Shah, Svati H and Kraus, William E and Rader, Daniel J and Chen, Yii-Der I and Hveem, Kristian and Wareham, Nicholas John and Kathiresan, Sekar and Melander, Olle and Stefansson, Kari and Nordestgaard, Børge G and Tybjærg-Hansen, Anne and Abecasis, Goncalo R and Altshuler, David and Florez, Jose C and Boehnke, Michael and McCarthy, Mark I and Yancopoulos, George D and Carey, David J and Shuldiner, Alan R and Baras, Aris and Dewey, Frederick E and Gromada, Jesper
ISSN 2041-1723, 2018
Journal Article
by Verma, Shefali Setia and Cooke Bailey, Jessica N and Lucas, Anastasia and Bradford, Yuki and Linneman, James G and Hauser, Michael A and Pasquale, Louis R and Peissig, Peggy L and Brilliant, Murray H and McCarty, Catherine A and Haines, Jonathan L and Wiggs, Janey L and Vrabec, Tamara R and Tromp, Gerard and Ritchie, Marylyn D and Bickel, Jonathan and Chandler, Ariel and Holm, Ingrid and Kohane, Isaac and Manzi, Shannon and Markianos, Kyriacos and Palmer, Nathan and Perry, Cassandra and Savova, Guergana and Wolf, Wendy and Wong Kong, Sek and Antommaria, Armand and Cobb, Beth and Harley, John and Hutton, John and Lingren, Todd and Lynch, John and Marsolo, Keith and Myers, Melanie and Namjou, Bahram and Prows, Cindy and Solti, Imre and Vinks, Sander and Wagner, Michael and Abrams, Debbie and Almoguera, Berta and Chiavacci, Rosetta and Connolly, John and Devoto, Marcella and Hakonarson, Hakon and Keating, Brendan and Kim, Cecilia and Mentch, Frank and Qui, Haijun and Sleiman, Patrick and Tian, Lifeng and Vazquez, Lyam and Bartko, Brynn and Bock, Jonathan and Borthwick, Ken and Carey, David and Colonie, Ryan and Elston, Robert and Faucett, Andy and Fetterolf, Samantha and Gerhard, Glenn and Kuivaniemi, Helena and Ledbetter, David and Lipsky, Eric and Pendergrass, Sarah and Sundaresan, Agnes and Smelser, Diane and Williams, Janet and Williams, Marc and Wood, Craig and Albrecht, Jen and Carlson, Chris and Carrell, David and Crane, Paul and Cronkite, David and Crosslin, David and Davis, Colleen and Ehrlich, Kelly and Fullterton, Malia and Gallego, Carlos and Gordon, Adam and Grafton, Jane and Hansen, Kelly and Hartzler, Andrea and Jarvik, Gail and Larson, Eric and Leppig, Kathy and Mukherjee, Shubhabrata and Ralston, James and Scrol, Aaron and Tarczy-Hornoch, Peter and Trinidad, Sue and Bielinski, Sue and Bruce, Kevin and Chute, Chris and De Andrade, Mariza and Jouni, Hayan and Heit, John and Isseh, Iyad and Koenig, Barbara and ... and NEIGHBOR Consortium and eMERGE Network
PLoS Genetics, ISSN 1553-7390, 09/2016, Volume 12, Issue 9, pp. e1006186 - e1006186
Journal Article
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