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Journal of Enzyme Inhibition and Medicinal Chemistry, ISSN 1475-6366, 01/2018, Volume 33, Issue 1, pp. 560 - 566
Journal Article
Journal of Pharmacy and Pharmacology, ISSN 0022-3573, 02/2015, Volume 67, Issue 2, pp. 244 - 254
Journal Article
JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, ISSN 0867-5910, 02/2019, Volume 70, Issue 1, pp. 15 - 23
Tachykinins act as neurotransmitters and neuromodulators in the central and peripheral nervous system. Preclinical studies and clinical trials showed that... 
LOCALIZATION | PHYSIOLOGY | irritable bowel syndrome | transient receptor potential vanilloid 1 channel | tachykinins | NEUROKININ-A | diarrhea | FUNCTIONAL GASTROINTESTINAL DISORDERS | PATHOPHYSIOLOGY | abdominal pain | CIRCULAR MUSCLE | SMOOTH-MUSCLE | 2 FORMS | NK2 receptor antagonist | MOTOR-RESPONSES | ibodutant | SUBSTANCE-P
Journal Article
Journal Article
Mini-Reviews in Medicinal Chemistry, ISSN 1389-5575, 12/2016, Volume 16, Issue 18, pp. 1462 - 1469
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a frequent functional disorder of the gastrointestinal (GI) tract affecting nearly one fifth of the... 
Diarrhea | MOP/DOP receptor ligands | Opioid receptors | Irritable bowel syndrome | Opioids | opioid receptors | BIPHALIN | CHEMISTRY, MEDICINAL | irritable bowel syndrome | DELTA-OPIOID RECEPTOR | BETA-ENDORPHIN | INHIBITION | THERAPY | KAPPA | ELUXADOLINE | SUBSTANCE-P | opioids | MOLECULAR-MECHANISMS
Journal Article
Neurogastroenterology & Motility, ISSN 1350-1925, 11/2014, Volume 26, Issue 11, pp. 1539 - 1550
Journal Article
Journal of Molecular Medicine, ISSN 0946-2716, 12/2015, Volume 93, Issue 12, pp. 1297 - 1309
Recent studies implicate TRPV4 receptors in visceral pain signaling and intestinal inflammation. Our aim was to evaluate the role of TRPV4 in the control of... 
Human Genetics | Biomedicine | Nitric oxide synthase type 1 | Irritable bowel syndrome | Internal Medicine | Molecular Medicine | Myenteric plexus | MEDICINE, RESEARCH & EXPERIMENTAL | ION-TRANSPORT | NITRIC-OXIDE SYNTHASE | CATION CHANNEL | DORSAL-ROOT GANGLION | DISTAL COLON | HEAT-EVOKED ACTIVATION | MECHANICAL HYPERALGESIA | ENDOTHELIAL-CELLS | GENETICS & HEREDITY | TRPV4 CHANNELS | CHRONIC COMPRESSION | Leucine - pharmacology | Colon - physiology | Synaptic Transmission - genetics | Humans | Middle Aged | Colon - drug effects | Gastrointestinal Motility - drug effects | Male | Myenteric Plexus - metabolism | Case-Control Studies | Muscle, Smooth - drug effects | TRPV Cation Channels - metabolism | TRPV Cation Channels - antagonists & inhibitors | Aged, 80 and over | Adult | Colon - physiopathology | Female | Leucine - analogs & derivatives | Disease Models, Animal | Gene Expression | Irritable Bowel Syndrome - metabolism | Gastrointestinal Motility - genetics | Guanylate Cyclase - metabolism | Irritable Bowel Syndrome - drug therapy | Irritable Bowel Syndrome - physiopathology | Muscle, Smooth - metabolism | Sulfonamides - pharmacology | Irritable Bowel Syndrome - genetics | TRPV Cation Channels - genetics | Mice, Knockout | Animals | Models, Biological | Muscle Contraction - drug effects | Aged | Mice | Nitric Oxide Synthase - metabolism | Nitric Oxide - metabolism | Cell receptors | Nitric oxide | Physiological aspects | Phenols | Neural transmission | Health aspects
Journal Article
PHARMACOLOGICAL REPORTS, ISSN 1734-1140, 10/2019, Volume 71, Issue 5, pp. 899 - 908
Background: Dietary interventions can improve gastrointestinal (GI) symptoms. We determined the effects of fatty acids (FAs) supplementation with medium- and... 
CHOLECYSTOKININ | GPR43 | APPETITE RESPONSES | PROTEIN-COUPLED RECEPTORS | Gastrointestinal motility | Inflammation | ENERGY-INTAKE | Fatty acid binding protein 4 | BOWEL-DISEASE | GUT MOTILITY | PLASMA CCK | INHIBITION | Free fatty acid receptors | ANTROPYLORODUODENAL MOTILITY | PHARMACOLOGY & PHARMACY | Saturated fatty acids
Journal Article
Current Drug Targets, ISSN 1389-4501, 2015, Volume 16, Issue 3, pp. 219 - 225
Platelets play a crucial role in immune responses. Impaired platelet activation may cause persistent mucosal inflammation through P-selectin, CD40-CD40L and... 
Inflammatory bowel diseases | Anti-platelet agents | Platelets | Thrombosis | HUMAN INTERLEUKIN-6 | RISK-FACTORS | inflammatory bowel diseases | CROHNS-DISEASE | THROMBOXANE SYNTHASE INHIBITOR | ULCERATIVE-COLITIS | platelets | ACTIVATED PLATELETS | BLOOD-PLATELETS | thrombosis | P-SELECTIN | PHARMACOLOGY & PHARMACY | SODIUM-INDUCED COLITIS | CD40 LIGAND EXPRESSION
Journal Article
Peptides, ISSN 0196-9781, 2009, Volume 30, Issue 3, pp. 545 - 556
Journal Article