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Scientific Reports, ISSN 2045-2322, 01/2015, Volume 5, Issue 1, p. 7857
We characterized the mutational landscape of human skin cutaneous melanoma (SKCM) using data obtained from The Cancer Genome Atlas (TCGA) project. We analyzed... 
INHIBITION | GENE | LANDSCAPE | MULTIDISCIPLINARY SCIENCES | IMPROVED SURVIVAL | MUTATIONS | CILIOGENESIS | Cell Proliferation - genetics | Melanoma - genetics | Proto-Oncogene Proteins B-raf - genetics | Genomics | Humans | Skin Neoplasms | Adult | Male | Melanoma - pathology | Mutation | Systems Biology | DNA Copy Number Variations | Signal transduction | Genomes | Gene expression | Melanoma | Cancer
Journal Article
Pigment Cell & Melanoma Research, ISSN 1755-1471, 05/2012, Volume 25, Issue 3, pp. 375 - 383
Summary The tricarboxylic acid (TCA) cycle is the central hub of oxidative metabolism, running in the classic forward direction to provide carbon for... 
13C | hypoxia | NMR | flux | metabolism | reductive carboxylation | IDH | Flux | Hypoxia | Metabolism | Reductive carboxylation | RAT-LIVER | MITOCHONDRIA | CANCER | GLUTAMINE-METABOLISM | CELL BIOLOGY | DERMATOLOGY | GLYCOLYSIS | HEART | ONCOLOGY | GROWTH | CARBOXYLATION | FATTY-ACID SYNTHASE | ISOTOPOMER | Gene Expression Regulation, Enzymologic - drug effects | Melanoma - complications | Humans | Gene Knockdown Techniques | Hypoxia - metabolism | Lipogenesis - genetics | Melanoma - genetics | Metabolic Networks and Pathways - physiology | Lipogenesis - physiology | Melanoma - metabolism | Skin Neoplasms - pathology | RNA, Small Interfering - pharmacology | Citric Acid Cycle - drug effects | Isocitrate Dehydrogenase - genetics | Hypoxia - complications | Melanoma - pathology | Isocitrate Dehydrogenase - physiology | Skin Neoplasms - metabolism | Skin Neoplasms - complications | Citric Acid Cycle - genetics | Hypoxia - genetics | Metabolic Networks and Pathways - genetics | Hypoxia - pathology | Models, Biological | Lipogenesis - drug effects | Skin Neoplasms - genetics | Cell Line, Tumor | Isocitrate Dehydrogenase - metabolism | Citric Acid Cycle - physiology | Metabolic Networks and Pathways - drug effects | Glucose metabolism | Tracers (Biology) | Metabolites | Melanoma | Oxidoreductases | Glucose | Fatty acids | Dextrose | Cells | Glutamine
Journal Article
Physical Review Letters, ISSN 0031-9007, 01/2006, Volume 96, Issue 1, p. 013901
We introduce a background-free real-time detection scheme capable of recognizing low-index nanoparticles such as single viruses in water. The method is based... 
NANOPARTICLES | GOLD | PHYSICS, MULTIDISCIPLINARY | MICROSCOPY | OPTICAL GRADIENT FORCES | Microfluidic Analytical Techniques - methods | Influenza A virus - chemistry | Interferometry - methods | Lasers | Nanostructures - chemistry | Nanostructures - analysis | Scattering, Radiation | Optics and Photonics
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 05/2019, Volume 9, Issue 1, pp. 7696 - 11
Dysregulation of signaling networks controlling self-renewal and migration of developmental cell lineages is closely linked to the proliferative and invasive... 
INITIATING CELLS | APOPTOSIS | P75 NEUROTROPHIN RECEPTOR | THERAPY | MARKER | MULTIDISCIPLINARY SCIENCES | BIOLOGY | KINASE | CANCER | Transcription factors | Transformation | Senescence | TRAF6 protein | Cell survival | p53 Protein | Melanoma | Cell lineage | Melanocytes | Myc protein | Gene expression | Signal transduction | E2F protein | Cell fate | Nerve growth factor receptors | Cell death | Transduction | Cell migration | Apoptosis | Tumors
Journal Article
npj Systems Biology and Applications, ISSN 2056-7189, 12/2018, Volume 4, Issue 1, pp. 24 - 10
Coordinated experiments focused on transcriptional responses and chromatin states are well-equipped to capture different epigenomic and transcriptomic levels... 
DEMETHYLASE | ANDROGEN RECEPTOR | KDM4B | IMPACT | GENE | MATHEMATICAL & COMPUTATIONAL BIOLOGY | DYNAMICS | DIFFERENTIATION | JMJD1A | JHDM2A | EXPRESSION | Chromatin | Transcription factors | Activator protein 1 | Genomes | Myc protein | Sp1 protein | Cofactors | Gene silencing | Lysine | Cooperation | Transcription activation | Histones | Helix-loop-helix proteins | Deoxyribonucleic acid--DNA | Cancer
Journal Article
Molecular Cancer Research, ISSN 1541-7786, 02/2016, Volume 14, Issue 2, pp. 196 - 206
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2019, Volume 76, Issue 4, pp. 531 - 545.e5
Journal Article
Nature Communications, ISSN 2041-1723, 06/2015, Volume 6, Issue 1, p. 7101
Drug side effects cause a significant clinical and economic burden. However, mechanisms of drug action underlying side effect pathogenesis remain largely... 
NETWORK | TRANSPORT | GENE | GLOBAL RECONSTRUCTION | MULTIDISCIPLINARY SCIENCES | NITRIC-OXIDE | CONSTRAINT-BASED MODELS | IDENTIFICATION | FOLIC-ACID | EXPRESSION | PREDICTION | Pharmacogenetics | Drug-Related Side Effects and Adverse Reactions | Humans | Databases, Factual
Journal Article