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European journal of immunology, ISSN 0014-2980, 01/2013, Volume 43, Issue 1, pp. 9 - 10
Journal Article
HISTORIA, ISSN 1270-0835, 04/2019, Issue 868, pp. 74 - 74
Journal Article
Journal Article
EMBO Reports, ISSN 1469-221X, 05/2007, Volume 8, Issue 5, pp. 429 - 432
  Alain Fischer, immunologist and gene therapist at the Necker Hospital in Paris, France, is interviewed. Fischer talks about his work in severe immune... 
Genetic Therapy | Humans | Paris | Allergy and Immunology | Patient safety | Clinical trials | Immunology | Gene therapy | Index Medicus | Science and Society
Journal Article
2014, Leçons inaugurales du Collège de France, ISBN 9782213685663, Volume 248
Web Resource
2014, Leçons inaugurales du Collège de France, ISBN 9782213685663, Volume 248
Web Resource
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 09/2019, Volume 144, Issue 3, pp. 668 - 670
[...]WAS is a life-threatening disease that can only be cured by allogeneic hematopoietic stem cell transplantation (HSCT)2 or (as recently demonstrated) gene... 
Wiskott-Aldrich syndrome | gene therapy | platelets | Thrombocytopenia | Phenotypes | Reactive oxygen species | Stem cell transplantation | Transplantation | Hematopoietic stem cells | Hemopoiesis | Signal transduction | Hypotheses | Chemotherapy | Ultrastructure | Stem cells | Cytoskeleton | Transduction | Gene therapy | Platelets | Index Medicus | Abridged Index Medicus
Journal Article
The journal of gene medicine, ISSN 1099-498X, 07/2000, Volume 2, Issue 4, pp. 297 - 300
Journal Article
Nature, ISSN 0028-0836, 06/2014, Volume 510, Issue 7504, pp. 226 - 227
Other nucleases - for example, those modified from artificial restriction enzymes known as TALENs, or from RNA-guided enzymes based on the bacterial... 
Stem cell research | Care and treatment | Genetic disorders | Genetic research | Genetic engineering | Research | Gene therapy | Proteins | Enzymes | Cytokines | Stem cells | Genomes | Mutation | Deoxyribonucleic acid--DNA
Journal Article
Comptes Rendus - Biologies, ISSN 1631-0691, 07/2016, Volume 339, Issue 7-8, pp. 314 - 318
Gene therapy has become a reality, although still a fragile one. Clinical benefit has been achieved over the last 17 years in a limited number of medical... 
B-cell leukemia | Retroviruses | Severe combined immunodeficiency | Gene editing | Gene therapy | Adeno-associated viruses | Chimeric antigen receptors (CAR)
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 134, Issue 6, pp. 1354 - 1364.e6
Background Inflammatory bowel disease (IBD) is one of the most common chronic gastrointestinal diseases, but the underlying molecular mechanisms remain largely... 
Allergy and Immunology | Inflammatory bowel disease | immune deficiency | lymphocytes | RhoA kinase | cytoskeleton | gut organoid | cell homeostasis | tetratricopeptide repeat domain 7A deficiency | cytoskeleton gut organoid | CROHNS-DISEASE | DENDRITIC CELLS | ULCERATIVE-COLITIS | IMMUNOLOGY | PLASMA-MEMBRANE | INFLAMMATORY-BOWEL-DISEASE | GENE | ALLERGY | RHO GTPASES | FLAKY SKIN | ANEMIA | TTC7A MUTATIONS | rhoA GTP-Binding Protein - immunology | Alopecia - immunology | Humans | Inflammatory Bowel Diseases - immunology | Middle Aged | Child, Preschool | Infant | Male | Mutation, Missense | Lymphopenia - pathology | rho-Associated Kinases - antagonists & inhibitors | Young Adult | Alopecia - genetics | Inflammatory Bowel Diseases - pathology | Inflammatory Bowel Diseases - genetics | Adult | Female | Child | Colon - pathology | Pyloric Antrum - pathology | Proteins - immunology | Alopecia - pathology | Proteins - genetics | Duodenum - pathology | Adolescent | rho-Associated Kinases - immunology | Lymphopenia - immunology | Lymphopenia - genetics | Developmental biology | Gastrointestinal diseases | Stem cells | Immunodeficiency | Autoimmunity | Alopecia | Baldness | Analysis | Lymphocytopenia | Studies | Parenteral nutrition | Mutation | Patients | Age | Immune system | Apoptosis | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2017, Volume 140, Issue 5, pp. 1388 - 1393.e8
Journal Article
Revue Francophone des Laboratoires, ISSN 1773-035X, 05/2019, Volume 2019, Issue 512, pp. 36 - 41
Les bienfaits de la vaccination ne sont plus à démontrer. Pourtant celle-ci suscite opposition et doutes répandus par les réseaux sociaux et responsables d’une... 
responsibility | obligation | hésitation | hesitation | public health | responsabilité | santé publique | vaccination
Journal Article
Revue Francophone des Laboratoires, ISSN 1773-035X, 05/2019, Volume 2019, Issue 512, p. 36
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 134, Issue 1, pp. 116 - 126.e11
Background Common variable immunodeficiency (CVID) is an antibody deficiency with an equal sex distribution and a high variability in clinical presentation.... 
Allergy and Immunology | patient self-reported outcomes | treatment | Common variable immunodeficiency | primary antibody deficiency | autoimmunity | enteropathy | immunoglobulin replacement | quality of life | lymphadenopathy | granulomas | INFECTIONS | PHENOTYPES | IMMUNOLOGY | DEFICIENCY | IGM | TRIAL | B-CELL | ALLERGY | HYPOGAMMAGLOBULINEMIA | INTRAVENOUS IMMUNOGLOBULIN | DISEASE | Autoimmunity | Common Variable Immunodeficiency - immunology | Common Variable Immunodeficiency - drug therapy | Humans | Child, Preschool | Lymphoproliferative Disorders - complications | Male | Lymphoproliferative Disorders - immunology | Splenomegaly - pathology | Bronchiectasis - pathology | Common Variable Immunodeficiency - mortality | Pneumonia - mortality | Pneumonia - immunology | Adult | Female | Retrospective Studies | Child | Europe | Delayed Diagnosis | Common Variable Immunodeficiency - complications | Lymphoproliferative Disorders - mortality | Pneumonia - drug therapy | Immunoglobulins, Intravenous - therapeutic use | Adolescent | Age of Onset | Survival Analysis | Pneumonia - complications | Lymphoproliferative Disorders - drug therapy | Immunological deficiency syndromes | Care and treatment | Health aspects | Respiratory tract diseases | Studies | Pneumonia | Meningitis | Lymphomas | Multivariate analysis | Patients | Age | Data bases | Index Medicus | Abridged Index Medicus
Journal Article
Bulletin de l'Academie Nationale de Medecine, ISSN 0001-4079, 01/2017, Volume 201, Issue 1-3, pp. 273 - 279
Journal Article
Medecine/Sciences, ISSN 0767-0974, 02/2017, Volume 33, Issue 2, pp. 119 - 120
Journal Article
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 05/2017, Volume 139, Issue 5, pp. 1641 - 1649.e6
Chronic granulomatous disease (CGD) is a primary immunodeficiency caused by defective production of reactive oxygen species in phagocytic cells that results in... 
Chronic granulomatous disease | autophagy | IL-17A | inflammasome | IL-1β | inflammatory manifestations | mammalian target of rapamycin inhibition | ACTIVATION | DENDRITIC CELLS | IL-1 beta | IMMUNOLOGY | INTERLEUKIN-17 | ALLERGY | HEMATOPOIETIC STEM-CELLS | ROR-GAMMA | MICE | DIFFERENTIATION | HYPERINFLAMMATION | ALPHA BLOCKADE | Phagocytes - drug effects | Humans | Middle Aged | Child, Preschool | Infant | Male | Inflammation - immunology | Monocytes - immunology | Granulomatous Disease, Chronic - immunology | Phagocytes - immunology | Sirolimus - pharmacology | CD4-Positive T-Lymphocytes - immunology | Monocytes - drug effects | TOR Serine-Threonine Kinases - antagonists & inhibitors | Young Adult | Adolescent | Adult | Female | Interleukin 1 Receptor Antagonist Protein - pharmacology | Child | Immunosuppressive Agents - pharmacology | CD4-Positive T-Lymphocytes - drug effects | Cytokines - immunology | Care and treatment | Research | Oncology, Experimental | Immunodeficiency | Cancer | Disease | Fungicides | Central nervous system | Nervous system | Assaying | Caspase-1 | Fungi | Microorganisms | Diagnosis | Inhibition | Activation analysis | Cytokines | Patients | Inflammatory bowel disease | Stem cells | Adolescence | Animal models | Senescence | Correlation | Destruction | Calcium | Medical services | Stimulation | Arthritis | Transplantation | Fungal infections | Autophagy | Defects | Interleukin 6 | Interleukin 4 | Counterbalances | Lymphocytes | Intestine | Bacteria | Attenuation | Children | Adolescents | Digestive tract | Age | Oxygen | Statistical analysis | Attitude (inclination) | Hypersensitivity | Health risks | Caspase | Pharmacology | Statistics | Computer programs | Immune systems | Life span | Lungs | Differentiation | Index Medicus | Abridged Index Medicus
Journal Article