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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2005, Volume 102, Issue 6, pp. 2069 - 2074
Proprotein convertase subtilisin kexin 9 (PCSK9) is a member of the subtilisin serine protease family with an important role in cholesterol metabolism. PCSK9... 
Hep G2 cells | Biological Sciences | Endocytosis | Hypercholesterolemia | Adenoviruses | Chlorides | Cell lines | Lysosomes | Lipids | Physiological regulation | Cholesterols | Low-density lipoprotein receptor | Autosomal dominant hypercholesterolemia | Narc-1 | Proprotein convertase subtilisin kexin 9 | POSTTRANSCRIPTIONAL REGULATION | FAMILIAL HYPERCHOLESTEROLEMIA | proprotein | low-density lipoprotein receptor | AUTOSOMAL-DOMINANT HYPERCHOLESTEROLEMIA | RAPID DEGRADATION | MULTIDISCIPLINARY SCIENCES | QUALITY-CONTROL | RECESSIVE HYPERCHOLESTEROLEMIA | SECRETORY PATHWAY | MESSENGER-RNA | GENE-EXPRESSION | autosomal dominant hypercholesterolemia | convertase subtilisin kexin 9 | DENSITY-LIPOPROTEIN RECEPTOR | Cell Line | Receptors, LDL - genetics | Humans | Endoplasmic Reticulum - metabolism | Lysosomes - enzymology | Receptors, LDL - metabolism | Serine Proteinase Inhibitors - metabolism | Cholesterol - metabolism | Animals | Biological Transport | Serine Endopeptidases - genetics | Mice | Serine Endopeptidases - metabolism | Proprotein Convertases | Proteasome Endopeptidase Complex - metabolism | Proteasome Inhibitors | Proprotein Convertase 9 | Low density lipoprotein receptors | Research | Proteases | Mice as laboratory animals | Medical research | Mutation | Rodents | Cholesterol | Index Medicus | proprotein convertase subtilisin kexin 9
Journal Article
Journal for ImmunoTherapy of Cancer, ISSN 2051-1426, 12/2014, Volume 2, Issue 1
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2011, Volume 108, Issue 17, pp. 7166 - 7171
HDL cholesterol (HDL-C) plasma levels are inversely related to cardiovascular disease risk. Previous studies have shown in animals and humans that HDL promotes... 
Thoracic aorta | Monocytes | Messenger RNA | Dendritic cells | HDL lipoproteins | Atherosclerosis | Transplantation | Macrophages | Gene expression | Cholesterols | Arginase I | Alternative activation | HEART-DISEASE | alternative activation | CORONARY ATHEROSCLEROSIS | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | arginase I | DIRECTED GENE-TRANSFER | E-DEFICIENT MICE | MACROPHAGE ACTIVATION | HIGH-DENSITY-LIPOPROTEIN | APOLIPOPROTEIN-A-I | TRANSGENIC MICE | Atherosclerosis - pathology | Cholesterol, HDL - metabolism | Atherosclerosis - genetics | Humans | Receptors, CCR7 - genetics | Monocytes - metabolism | Aorta - metabolism | Cholesterol, HDL - genetics | Antigens, CD - genetics | Antigens, Differentiation, Myelomonocytic - genetics | Atherosclerosis - metabolism | Antigens, CD - metabolism | Mice, Knockout | Animals | Receptors, CCR7 - metabolism | Antigens, Differentiation, Myelomonocytic - metabolism | Apolipoproteins E - genetics | Monocytes - pathology | Mice | Foam Cells - pathology | Foam Cells - metabolism | Aorta - transplantation | Disease Models, Animal | Development and progression | Genetic aspects | Inflammation | Health aspects | Cholesterol | Plasma | Transgenic animals | Rodents | Apolipoproteins | Cells | Index Medicus | CC chemokine receptors | Animal models | CCR7 protein | Transgenic mice | phenotypic plasticity | Regression analysis | Chemokine receptors | Aortic arch | Arteriosclerosis | Plasma levels | Cardiovascular diseases | Lipoproteins (high density) | Cell migration | Plaques | Biological Sciences
Journal Article
Journal for ImmunoTherapy of Cancer, ISSN 2051-1426, 07/2014, Volume 2, Issue 1
Journal Article
Cancer Research, ISSN 0008-5472, 08/2015, Volume 75, Issue 15 Supplement, pp. 3158 - 3158
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 07/2017, Volume 16, Issue 7, pp. 1335 - 1346
Journal Article
Journal for immunotherapy of cancer, ISSN 2051-1426, 2014, Volume 2, p. 22
Journal Article
Journal for ImmunoTherapy of Cancer, 07/2014, Volume 2, Issue 1
Journal Article
Neuro-Oncology, ISSN 1522-8517, 4/2011, Volume 13, Issue 4, pp. 393 - 400
Journal Article
Journal of Immunotherapy, ISSN 1524-9557, 05/2011, Volume 34, Issue 4, pp. 382 - 389
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2012, Volume 7, Issue 12, pp. e50221 - e50221
Lymphocytes are a key component of the immune system and their differentiation and function are directly influenced by cancer. We examined peripheral blood... 
TUMOR-INFILTRATING LYMPHOCYTES | THERAPY | LEUKOCYTES | IMMUNOTHERAPY | CHEMOKINES | MULTIDISCIPLINARY SCIENCES | GROWTH | REGULATORY T-CELLS | MONONUCLEAR-CELLS | CANCER STATISTICS | FLT3 LIGAND | Lymphocytes - metabolism | Kidney Neoplasms - genetics | Carcinoma, Renal Cell - blood | Oligonucleotide Array Sequence Analysis | Dendritic Cells - immunology | Humans | Middle Aged | Interferon-alpha - therapeutic use | Interleukin-2 - therapeutic use | Carcinoma, Renal Cell - genetics | Male | Gene Expression Profiling | Kidney Neoplasms - blood | Cancer Vaccines - therapeutic use | Flow Cytometry | Lymphocyte Subsets | Carcinoma, Renal Cell - therapy | Female | Real-Time Polymerase Chain Reaction | Kidney Neoplasms - therapy | Cluster Analysis | Cytokines - blood | Flow cytometry | Target recognition | Clinical trials | Cytotoxicity | Oncology | Lymphocytes T | Metastasis | Vaccines | B-cell receptor | Cotton | Cancer therapies | Blood | Medical schools | Anticancer properties | Metastases | Cell activation | Pathways | Interleukin 2 | Lymphocytes | Immunotherapy | Peripheral blood | Combined vaccines | Down-regulation | Bioindicators | Pretreatment | Immune system | Cytokines | Hematology | Dendritic cells | Inflammation | Gene expression | Patients | Medicine | Cytometry | Signaling | Lymphocytes B | Biomarkers | Ligands | Interferon | Combined treatment | Clear cell-type renal cell carcinoma | Kidney transplantation | Cancer | Index Medicus
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 08/2009, Volume 15, Issue 15, pp. 4986 - 4992
Purpose: To evaluate the clinical and immunologic outcomes of DC (dendritic cell) vaccine with interleukin (IL)-2 and IFN-α 2a in metastatic renal cell... 
IFN-α | renal cell carcinoma | tumor vaccine therapy | interleukin 2 | dendritic cell vaccine | immunotherapy
Journal Article
Cancer Immunology, Immunotherapy, ISSN 0340-7004, 3/2017, Volume 66, Issue 3, pp. 379 - 389
Journal Article