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Protein Science, ISSN 0961-8368, 10/2019
Journal Article
Journal Article
07/2018, Topics in Medicinal Chemistry, ISBN 3319708384, Volume 26, 222
Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art... 
Antibacterial agents | Medicinal Chemistry | Biochemistry, general | Chemistry | Organic Chemistry | Pharmaceutical chemistry
eBook
Chemical Reviews, ISSN 0009-2665, 06/2018, Volume 118, Issue 12, p. 5952
The importance of the cell wall to the viability of the bacterium is underscored by the breadth of antibiotic structures that act by blocking key enzymes that... 
Enzymes | Bacterial physiology | Deactivation | Antibiotics | Antibiotic resistance | Bacteria | Amides | Gram-negative bacteria | Drug resistance | Gene expression | Viability
Journal Article
07/2018, Topics in Medicinal Chemistry, ISBN 331968096X, Volume 25, 203
Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art... 
Antibacterial agents | Medicinal Chemistry | Biochemistry, general | Chemistry | Organic Chemistry | Pharmaceutical chemistry
eBook
Annual Review of Microbiology, ISSN 0066-4227, 10/2011, Volume 65, Issue 1, pp. 455 - 478
β-Lactamase evolution presents to the infectious disease community a major challenge in the treatment of infections caused by multidrug-resistant gram-negative... 
carbapenemase | β-lactam | cephalosporinase | cephalosporin | resistance | Resistance | Carbapenemase | Cephalosporinase | Cephalosporin | ACTIVE-SITE | CTX-M ENZYMES | CRYSTAL-STRUCTURE | ANTIBIOTIC-RESISTANCE | BIOCHEMICAL-CHARACTERIZATION | MICROBIOLOGY | beta-lactam | ACINETOBACTER-BAUMANNII | RESISTANT ESCHERICHIA-COLI | OXA-TYPE CARBAPENEMASES | X-RAY-ANALYSIS | KLEBSIELLA-PNEUMONIAE | Bacterial Proteins - antagonists & inhibitors | Humans | Bacterial Proteins - chemistry | Bacterial Proteins - genetics | Enzyme Inhibitors - pharmacology | Gram-Negative Bacterial Infections - drug therapy | Gram-Negative Bacteria - enzymology | Gram-Negative Bacterial Infections - microbiology | Anti-Bacterial Agents - therapeutic use | Gram-Negative Bacteria - drug effects | beta-Lactamases - chemistry | Animals | beta-Lactamases - genetics | Gram-Negative Bacteria - chemistry | Drug Resistance, Multiple, Bacterial | Gram-Negative Bacterial Infections - epidemiology | Bacterial Proteins - metabolism | Anti-Bacterial Agents - pharmacology | Gram-Negative Bacteria - genetics | beta-Lactamase Inhibitors | beta-Lactamases - metabolism | Physiological aspects | Beta lactamases | Research | Gram-negative bacteria | Epidemiology | Enzymes | Pathogens | Serine | Inosine monophosphate | Drug resistance | Hydrolysis | Infection | beta -Lactamase | Infectious diseases | Reviews | Inactivators | Evolution | Metallo- beta -lactamase | beta -Lactam antibiotics | Structure-function relationships
Journal Article