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1. Full Text The Transcription Factor GATA3 Is Essential for the Function of Human Type 2 Innate Lymphoid Cells
by Mjösberg, Jenny and Bernink, Jochem and Golebski, Korneliusz and Karrich, Julien J and Peters, Charlotte P and Blom, Bianca and te Velde, Anje A and Fokkens, Wytske J and van Drunen, Cornelis M and Spits, Hergen
Immunity, ISSN 1074-7613, 10/2012, Volume 37, Issue 4, pp. 649 - 659
Type 2 innate lymphoid cells (ILC2s) are part of a large family of ILCs that are important effectors in innate immunity, lymphoid organogenesis, and tissue... 
ADAPTIVE IMMUNITY | HYPERREACTIVITY | CYTOKINES | FAMILY-MEMBERS | AIRWAY INFLAMMATION | DIFFERENTIATION | IMMUNOLOGY | EXPRESSION | LUNG INFLAMMATION | THYMIC STROMAL LYMPHOPOIETIN | TH2 | Cell Line | Nasal Polyps - immunology | GATA3 Transcription Factor - immunology | Humans | Gene Expression Regulation | STAT5 Transcription Factor - immunology | Interleukin-13 - immunology | Immunity, Innate | Interleukin-13 - biosynthesis | Epithelium - immunology | Lymphocytes - immunology | Receptors, Cytokine - immunology | Receptors, Cytokine - genetics | Cytokines - immunology | Developmental biology | Transcription factors | Cytokines | Cloning | Immune system | Asthma
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2. Full Text Allergic Rhinitis and its Impact on Asthma (ARIA) Phase 4 (2018): Change management in allergic rhinitis and asthma multimorbidity using mobile technology
by Bousquet, Jean and Hellings, Peter W and Agache, Ioana and Amat, Flore and Annesi-Maesano, Isabella and Ansotegui, Ignacio J and Anto, Josep M and Bachert, Claus and Bateman, Eric D and Bedbrook, Anna and Bennoor, Kazi and Bewick, Mickael and Bindslev-Jensen, Carsten and Bosnic-Anticevich, Sinthia and Bosse, Isabelle and Brozek, Jan and Brussino, Luisa and Canonica, Giorgio W and Cardona, Victoria and Casale, Thomas and Cepeda Sarabia, Alfonso M and Chavannes, Niels H and Cecchi, Lorenzo and Correia de Sousa, Jaime and Costa, Elisio and Cruz, Alvaro A and Czarlewski, Wienczyslawa and De Carlo, Giuseppe and De Feo, Giulia and Demoly, Pascal and Devillier, Philippe and Dykewicz, Mark S and El-Gamal, Yehia and Eller, Esben E and Fonseca, Joao A and Fontaine, Jean-François and Fokkens, Wytske J and Guzmán, Maria-Antonieta and Haahtela, Tari and Illario, Maddalena and Ivancevich, Juan-Carlos and Just, Jocelyne and Kaidashev, Igor and Khaitov, Musa and Kalayci, Omer and Keil, Thomas and Klimek, Ludger and Kowalski, Marek L and Kuna, Piotr and Kvedariene, Violeta and Larenas-Linnemann, Desiree and Laune, Daniel and Le, Lan T.T and Carlsen, Karin Lodrup and Lourenço, Olga and Mahboub, Bassam and Mair, Alpana and Menditto, Enrica and Milenkovic, Branislava and Morais-Almeida, Mario and Mösges, Ralph and Mullol, Joaquim and Murray, Ruth and Naclerio, Robert and Namazova-Baranova, Leyla and Novellino, Ettore and O'Hehir, Robyn E and Ohta, Ken and Okamoto, Yoshitaka and Okubo, Kimi and Onorato, Gabrielle L and Palkonen, Susanna and Panzner, Petr and Papadopoulos, Nikos G and Park, Hae-Sim and Paulino, Ema and Pawankar, Ruby and Pfaar, Oliver and Plavec, Davor and Popov, Ted A and Potter, Paul and Prokopakis, Emmanuel P and Rottem, Menachem and Ryan, Dermot and Salimäki, Johanna and Samolinski, Boleslaw and Sanchez-Borges, Mario and Schunemann, Holger J and Sheikh, Aziz and Sisul, Juan-Carlos and Rajabian-Söderlund, Rojin and Sooronbaev, Talant and Stellato, Cristiana and To, Teresa and Todo-Bom, Ana-Maria and Tomazic, Peter-Valentin and Toppila-Salmi, Sanna and Valero, Antonio and Valiulis, Arunas and Valovirta, Erkka and ... and Mobile Airways Sentinel Network (MASK) Study Group and Mobile Airways Sentinel Network M and Institutionen för datavetenskap and Umeå universitet and Teknisk-naturvetenskapliga fakulteten
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 03/2019, Volume 143, Issue 3, pp. 864 - 879
Allergic Rhinitis and its Impact on Asthma (ARIA) has evolved from a guideline by using the best approach to integrated care pathways using mobile technology... 
Change management | rhinitis | asthma | Allergic Rhinitis and Its Impact on Asthma | GLOBAL STRATEGY | QUALITY | MASK-RHINITIS | WORK PRODUCTIVITY | GUIDELINES | IMMUNOLOGY | CHRONIC DISEASES | PATIENT PARTICIPATION | DECISION-MAKING | ALLERGY | EUROPEAN INNOVATION PARTNERSHIP | MACVIA-ARIA | Rhinitis | Analysis | Health care | Portable computers | Innovations | Otolaryngology | Socioeconomics | Phase transitions | Empowerment | Immunology | Wireless networks | Technology | Allergic rhinitis | Public health | Technology utilization | Activities of daily living | Comorbidity | Decision making | Lung diseases | Socio-economic aspects | Management | Information technology | Patients | Allergies | Asthma | Medicine | Hospitals | Life cycle analysis | Pharmacy | Drug stores | Allergic Rhinitis | Asma | Rinitis | Life Sciences | Human health and pathology | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Lungmedicin och allergi | Klinisk medicin | Respiratory Medicine and Allergy
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3. Full Text Recent developments and highlights in rhinitis and allergen immunotherapy
by Reitsma, Sietze and Subramaniam, Soma and Fokkens, Wytske W. J and Wang, De Yun
Allergy, ISSN 0105-4538, 12/2018, Volume 73, Issue 12, pp. 2306 - 2313
This review paper aims to provide an overview of recent developments in the field of allergic and non‐allergic rhinitis, as well as allergen immunotherapy.... 
allergic rhinitis | allergen immunotherapy | local allergic rhinitis | non‐allergic rhinitis | non-allergic rhinitis | NASAL INSPIRATORY FLOW | HOUSE-DUST-MITE | MP-AZEFLU | DERMATOPHAGOIDES-PTERONYSSINUS | IMMUNOLOGY | VENOM ALLERGY | REAL-LIFE | ALLERGY | DOUBLE-BLIND | NONALLERGIC RHINITIS | EAACI GUIDELINES | SUBLINGUAL TABLET | Histamine | Allergens | Rhinitis | Immunotherapy | Allergic rhinitis | Nose | Phenotyping | Allergies
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4. Full Text Allergic Rhinitis and its Impact on Asthma (ARIA) Guidelines – 2016 Revision
by Brożek, Jan L., MD, PhD and Bousquet, Jean, MD, PhD and Agache, Ioana, MD, PhD and Agarwal, Arnav, BHSc and Bachert, Claus, MD PhD and Bosnic-Anticevich, Sinthia, BPharm, PhD and Brignardello-Petersen, Romina, DDS, MSc, PhD and Canonica, G. Walter, MD and Casale, Thomas, MD and Chavannes, Niels H., MD, PhD and Correia de Sousa, Jaime, MD, PhD and Cruz, Alvaro A and Cuello-Garcia, Carlos A., MD and Demoly, Pascal, MD, PhD and Dykewicz, Mark, MD and Etxeandia-Ikobaltzeta, Itziar, PhD and Florez, Ivan D., MD, MSc and Fokkens, Wytske, MD, PhD and Fonseca, Joao, MD, PhD and Hellings, Peter W., MD, PhD and Klimek, Ludger, MD, PhD and Kowalski, Sergio, MD and Kuna, Piotr, MD, PhD and Laisaar, Kaja-Triin, MD, MPH and Larenas-Linnemann, Désirée E., MD and Lødrup Carlsen, Karin C., MD, PhD and Manning, Peter J., MD and Meltzer, Eli, MD and Mullol, Joaquim, MD, PhD and Muraro, Antonella, MD, PhD and O’Hehir, Robyn, PhD and Ohta, Ken, MD, PhD and Panzner, Petr, MD, PhD and Papadopoulos, Nikolaos, MD, PhD and Park, Hae-Sim, MD, PhD and Passalacqua, Gianni, MD and Pawankar, Ruby, MD, PhD and Price, David, MD and Riva, John J., MD and Roldán, Yetiani, MD and Ryan, Dermot, MD and Sadeghirad, Behnam, PharmD, MPH and Samolinski, Boleslaw, MD, PhD and Schmid-Grendelmeier, Peter, MD and Sheikh, Aziz, MD, MSc and Togias, Alkis, MD and Valero, Antonio, MD, PhD and Valiulis, Arunas, MD, PhD and Valovirta, Erkka, MD, PhD and Ventresca, Matthew, MSc and Wallace, Dana, MD and Waserman, Susan, MD, MSc and Wickman, Magnus, MD and Wiercioch, Wojtek, MSc and Yepes-Nuñez, Juan José, MD, MSc and Zhang, Luo, MD and Zhang, Yuan, MPH and Zidarn, Mihaela, MD, MSc and Zuberbier, Torsten, MD and Schünemann, Holger J., MD, PhD, MSc
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2017, Volume 140, Issue 4, pp. 950 - 958
Abstract Background Allergic rhinitis affects 10 to 40% of the population. It reduces quality of life, school and work performance, and is a frequent reason... 
Allergy and Immunology | practice guideline | Allergic rhinitis | RESPIRATORY-DISEASE | PREVALENCE | IMMUNOLOGY | ALLERGY | PERENNIAL RHINITIS | EUROPEAN INNOVATION PARTNERSHIP | HEALTH | GALEN | BURDEN | WORLD | INDEPENDENT RISK-FACTOR | Anti-Allergic Agents - therapeutic use | Animals | Asthma - prevention & control | Evidence-Based Practice | Histamine H1 Antagonists - therapeutic use | Clinical Decision-Making | Humans | Quality of Life | Rhinitis, Allergic - epidemiology | Child | Rhinitis, Allergic - drug therapy | Rhinitis | Practice guidelines (Medicine) | Analysis | Health care | Productivity | Corticoids | Antihistamines | Evaluation | Corticosteroids | Identification methods | Health care policy | Medical services | Pharmacology | Patients | Allergies | Asthma | Guidelines | Quality of life | Upgrading | Quality | Nose | Clinical medicine | Life Sciences
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5. Full Text Endotype-driven treatment in chronic upper airway diseases
by De Greve, Glynnis and Hellings, Peter W and Fokkens, Wytske J and Pugin, Benoit and Steelant, Brecht and Seys, Sven F
Clinical and Translational Allergy, ISSN 2045-7022, 07/2017, Volume 7, Issue 1, pp. 22 - 14
Rhinitis and rhinosinusitis are the two major clinical entities of chronic upper airway disease. Chronic rhinosinusitis (CRS) and allergic rhinitis (AR) affect... 
Biomarker | Phenotype | Chronic rhinosinusitis | Precision medicine | Rhinitis | Personalised medicine | Biologicals | SEVERE ASTHMA | FC-EPSILON-RI | REDUCES NASAL HYPERREACTIVITY | GRASS-POLLEN | ANTIIMMUNOGLOBULIN-E | ALLERGY | DOUBLE-BLIND | SEASONAL ALLERGIC RHINITIS | STAPHYLOCOCCUS-AUREUS | ANTI-IGE ANTIBODY | Comorbidity | Pharmacogenetics | Inflammation | Medicine | Genotype & phenotype | Immunotherapy | Nose | Biomarkers | Patients | Allergies | Asthma
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6. Full Text Inflammatory endotypes of chronic rhinosinusitis based on cluster analysis of biomarkers
by Tomassen, Peter, MD and Vandeplas, Griet, MD and Van Zele, Thibaut, MD, PhD and Cardell, Lars-Olaf, MD, PhD and Arebro, Julia, MD and Olze, Heidi, MD, PhD and Förster-Ruhrmann, Ulrike, MD and Kowalski, Marek L., MD, PhD and Olszewska-Ziąber, Agnieszka, MD and Holtappels, Gabriele and De Ruyck, Natalie and Wang, Xiangdong, MD, PhD and Van Drunen, Cornelis, PhD and Mullol, Joaquim, MD, PhD and Hellings, Peter, MD, PhD and Hox, Valerie, MD, PhD and Toskala, Elina, MD, PhD and Scadding, Glenis, MD and Lund, Valerie, MD and Zhang, Luo, MD, PhD and Fokkens, Wytske, MD, PhD and Bachert, Claus, MD, PhD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 137, Issue 5, pp. 1449 - 1456.e4
Background Current phenotyping of chronic rhinosinusitis (CRS) into chronic rhinosinusitis with nasal polyps (CRSwNP) and chronic rhinosinusitis without nasal... 
Allergy and Immunology | endotypes | nasal polyps | asthma | Chronic rhinosinusitis | cluster analysis | inflammation | ALLERGY | IGE | PHENOTYPES | IMMUNOLOGY | IDENTIFICATION | ASSOCIATION | Rhinitis - immunology | Peroxidase - immunology | Bacterial Toxins - immunology | Humans | Biomarkers - analysis | Male | Case-Control Studies | Immunoglobulin E - immunology | Enterotoxins - immunology | Sinusitis - immunology | Adult | Female | Staphylococcus aureus - immunology | Chronic Disease | Principal Component Analysis | Cluster Analysis | Cytokines - immunology | Medical colleges | Analysis | Hospitals | Immunoglobulin E | Studies | Cluster analysis | Genotype & phenotype | Surgery | Cystic fibrosis | Principal components analysis | Endoscopy | Allergies
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7. EP3OS 2007: European position paper on rhinosinusitis and nasal polyps 2007. A summary for otorhinolaryngologists
by Fokkens, Wytske J and Lund, Valerie and Mullol, Joaquim and European Position Paper on Rhinosinusitis and Nasal Polyps Group
Rhinology, ISSN 0300-0729, 06/2007, Volume 45, Issue 2, pp. 97 - 101
Rhinitis - therapy | Sinusitis - diagnosis | Humans | Sinusitis - therapy | Rhinitis - diagnosis | Nasal Polyps - diagnosis | Nasal Polyps - therapy
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8. Full Text Proposal for an Algorithm on the management of Chronic Rhinosinusitis
by Fokkens, Wytske J and Reitsma, Sietze
Allergy, ISSN 0105-4538, 2019
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9. Full Text Efficacy and safety of sublingual tablets of house dust mite allergen extracts in adults with allergic rhinitis
by Bergmann, Karl-Christian, MD and Demoly, Pascal, MD, PhD and Worm, Margitta, MD and Fokkens, Wytske J., MD, PhD and Carrillo, Teresa, MD, PhD and Tabar, Ana I., MD, PhD and Nguyen, Hélène, PharmD and Montagut, Armelle and Zeldin, Robert K., MD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2013, Volume 133, Issue 6, pp. 1608 - 1614.e6
Background Preliminary studies have suggested the efficacy of sublingual tablets of house dust mite (HDM) extracts in adults with allergic rhinitis. Objectives... 
Allergy and Immunology | sublingual immunotherapy tablets | placebo-controlled | house dust mite | Allergic rhinitis | double-blind | MONTELUKAST | IMMUNOLOGY | CHILDREN | ORGANIZATION | ALLERGY | PERENNIAL RHINITIS | IMMUNOTHERAPY | TOLERABILITY | CLINICAL-TRIALS | LORATADINE | ASTHMA | Administration, Sublingual | Rhinitis, Allergic, Perennial - immunology | Skin Tests | Immunoglobulin G - blood | Tablets | Rhinitis, Allergic | Humans | Rhinitis, Allergic, Perennial - therapy | Male | Treatment Outcome | Immunoglobulin E - blood | Young Adult | Antigens, Dermatophagoides - immunology | Animals | Desensitization, Immunologic - adverse effects | Immunoglobulin E - immunology | Immunoglobulin G - immunology | Antigens, Dermatophagoides - administration & dosage | Adult | Female | Pyroglyphidae - immunology | Rhinitis | Allergens | Adults | Clinical trials | Drug therapy | Immunotherapy | Allergies
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10. Full Text Medical algorithms: Management of chronic rhinosinusitis
by Fokkens, Wytske J and Reitsma, Sietze
Allergy, ISSN 0105-4538, 07/2019, Volume 74, Issue 7, pp. 1415 - 1416
ALLERGY | NASAL POLYPOSIS | IMMUNOLOGY | Algorithms | Sinuses | Rhinosinusitis | Medical treatment | Allergies
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11. Full Text IL-1β, IL-4 and IL-12 control the fate of group 2 innate lymphoid cells in human airway inflammation in the lungs
by Bal, Suzanne M and Bernink, Jochem H and Nagasawa, Maho and Groot, Jelle and Shikhagaie, Medya M and Golebski, Kornel and van nen, Cornelis M and Lutter, Rene and Jonkers, Rene E and Hombrink, Pleun and Bruchard, Melanie and Villaudy, Julien and Munneke, J. Marius and Fokkens, Wytske and Erjefält, Jonas S and Spits, Hergen and Ros, Xavier Romero and Luftvägsinflammation and Lund University and Airway Inflammation and Immunology and Lunds universitet
Nature immunology, ISSN 1529-2908, 2016, Volume 17, Issue 6, pp. 636 - 645
Group 2 innate lymphoid cells (ILC2s) secrete type 2 cytokines, which protect against parasites but can also contribute to a variety of inflammatory airway... 
ADULTS | ASTHMA | IMMUNOLOGY | EXPRESSION | NASAL POLYPS | DUPILUMAB | Nasal Polyps - immunology | Rhinitis - immunology | Lymphocyte Activation | Humans | Interleukin-4 - metabolism | Th1-Th2 Balance | Cells, Cultured | Interleukin-12 - metabolism | Th2 Cells - immunology | Interferon-gamma - metabolism | Immunity, Innate | Mice, SCID | Th1 Cells - immunology | Eosinophils - immunology | Animals | Lymphocytes - immunology | Interleukin-1beta - metabolism | Sinusitis - immunology | Pneumonia - immunology | Cell Plasticity | Female | Cell Differentiation | Mice | Pulmonary Disease, Chronic Obstructive - immunology | Clinical Medicine | Lungmedicin och allergi | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Respiratory Medicine and Allergy
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12. Full Text MACVIA clinical decision algorithm in adolescents and adults with allergic rhinitis
by Bousquet, Jean, MD and Schünemann, Holger J., MD and Hellings, Peter W., MD and Arnavielhe, Sylvie, PhD and Bachert, Claus, MD and Bedbrook, Anna, BSc and Bergmann, Karl-Christian, MD and Bosnic-Anticevich, Sinthia, PhD and Brozek, Jan, MD and Calderon, Moises, MD and Canonica, G. Walter, MD and Casale, Thomas B., MD and Chavannes, Niels H., MD and Cox, Linda, MD and Chrystyn, Henry, PhD and Cruz, Alvaro A., MD and Dahl, Ronald, MD and De Carlo, Giuseppe, MD and Demoly, Pascal, MD and Devillier, Phillipe, MD and Dray, Gérard, PhD and Fletcher, Monica, MSc and Fokkens, Wytske J., MD and Fonseca, Joao, MD and Gonzalez-Diaz, Sandra N., MD and Grouse, Lawrence, MD and Keil, Thomas, MD and Kuna, Piotr, MD and Larenas-Linnemann, Désirée, MD and Lodrup Carlsen, Karin C., MD and Meltzer, Eli O., MD and Mullol, Jaoquim, MD and Muraro, Antonella, MD and Naclerio, Robert N., MD and Palkonen, Susanna, MD and Papadopoulos, Nikolaos G., MD and Passalacqua, Giovanni, MD and Price, David, MD and Ryan, Dermot, MD and Samolinski, Boleslaw, MD and Scadding, Glenis K., MD and Sheikh, Aziz, MD and Valiulis, Arunas, MD and Valovirta, Erkka, MD and Walker, Samantha, PhD and Wickman, Magnus, MD and Yorgancioglu, Arzu, MD and Zuberbier, Torsten, MD and MASK Study Grp
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 138, Issue 2, pp. 367 - 374.e2
The selection of pharmacotherapy for patients with allergic rhinitis (AR) depends on several factors, including age, prominent symptoms, symptom severity,... 
Allergy and Immunology | clinical decision support system | MACVIA-LR | Allergic Rhinitis and its Impact on Asthma | conjunctivitis | information and communication technology | Allergic rhinitis | INTRANASAL THERAPY | MOMETASONE FUROATE | IMMUNOLOGY | FUROATE NASAL SPRAY | VISUAL ANALOG SCALE | IMPORTANT DIFFERENCE | PRIMARY-CARE | ALLERGY | EUROPEAN INNOVATION PARTNERSHIP | DOUBLE-BLIND | QUALITY-OF-LIFE | POSITION PAPER | Allergens | Algorithms | Rhinitis | Travelers | Chronic diseases | Youth | Teenagers | Chairpersons | Consulting services | Studies | Pain | Decision making |