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European Journal of Pharmacology, ISSN 0014-2999, 12/2017, Volume 816, pp. 1 - 2
Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 08/2017, Volume 37, Issue 8, pp. 1457 - 1461
Objective-Inflammasomes are multiprotein complexes, and their activation has been associated with cardiovascular disease. Inflammasome activation leads to... 
atherosclerosis | macrophages | inflammasomes | interleukin-1beta | CELLS | PROTEIN | INTERLEUKIN-1 RECEPTOR ANTAGONIST | CANAKINUMAB | CRYSTALS | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | EXPRESSION | Carotid Arteries - drug effects | Carotid Arteries - metabolism | Carotid Artery Diseases - prevention & control | Inflammasomes - metabolism | Apolipoproteins E - deficiency | Atherosclerosis - genetics | RNA, Messenger - metabolism | Sulfones - pharmacology | Heterocyclic Compounds, 4 or More Rings - pharmacology | Necrosis | Inflammasomes - antagonists & inhibitors | Time Factors | Carotid Artery Diseases - pathology | Interleukin-1beta - metabolism | Dendritic Cells - drug effects | Female | Vascular Cell Adhesion Molecule-1 - genetics | Carotid Artery Diseases - metabolism | Diet, Western | Dendritic Cells - metabolism | Disease Models, Animal | Atherosclerosis - pathology | Genetic Predisposition to Disease | Anti-Inflammatory Agents - pharmacology | NLR Family, Pyrin Domain-Containing 3 Protein - metabolism | Mice, Inbred C57BL | RNA, Messenger - genetics | Cells, Cultured | Crystallization | NLR Family, Pyrin Domain-Containing 3 Protein - antagonists & inhibitors | Plaque, Atherosclerotic | Atherosclerosis - metabolism | Mice, Knockout | Intercellular Adhesion Molecule-1 - metabolism | Macrophages - metabolism | Phenotype | Animals | Signal Transduction - drug effects | Apolipoproteins E - genetics | Intercellular Adhesion Molecule-1 - genetics | Carotid Artery Diseases - genetics | Lipopolysaccharides - pharmacology | Cholesterol - pharmacology | Macrophages - drug effects | Carotid Arteries - pathology | Vascular Cell Adhesion Molecule-1 - metabolism | Atherosclerosis - prevention & control
Journal Article
Atherosclerosis, ISSN 0021-9150, 01/2019, Volume 280, p. 118
Limiting the pro-inflammatory immune response is critical for the treatment of atherosclerosis. Regulatory B cells (Bregs) can modulate the immune response... 
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2018, Volume 13, Issue 1, p. e0190962
Journal Article
Atherosclerosis, ISSN 0021-9150, 01/2019, Volume 280, pp. 118 - 125
Limiting the pro-inflammatory immune response is critical for the treatment of atherosclerosis. Regulatory B cells (Bregs) can modulate the immune response... 
Western type diet | Interleukin-10 | Atherosclerosis | Cardiovascular disease | Regulatory B cells | B cells | Ldlr−/- mice | Ldlr | mice | CARDIAC & CARDIOVASCULAR SYSTEMS | TOLERANCE | B10 CELLS | LIGATION | SUBSET | LUPUS | PERIPHERAL VASCULAR DISEASE | Ldlr(-/-) mice | EXPRESSION
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 03/2016, Volume 36, Issue 3, pp. 456 - 465
OBJECTIVE—T cell immunoglobulin and mucin domain (Tim) proteins are expressed by numerous immune cells, recognize phosphatidylserine on apoptotic cells, and... 
atherosclerosis | apoptosis | macrophage | Tim | T cells | inflammation | COMMON VARIANTS | CLEARANCE | PHOSPHATIDYLSERINE RECEPTORS | INTERLEUKIN-4 | PHAGOCYTOSIS | REGULATORY B-CELLS | MACROPHAGES | TOLERANCE | INDUCTION | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | PROGRESSION | Antibodies, Monoclonal - toxicity | Apoptosis - drug effects | Atherosclerosis - genetics | Coculture Techniques | Male | Th2 Cells - immunology | CD4-Positive T-Lymphocytes - pathology | Th1 Cells - immunology | Aortic Diseases - chemically induced | Th2 Cells - drug effects | Aortic Diseases - metabolism | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Diet, High-Fat | Receptors, LDL - deficiency | Female | Lipoproteins, LDL - metabolism | Membrane Proteins - metabolism | Macrophages - immunology | Aortic Diseases - pathology | Disease Models, Animal | Receptors, LDL - genetics | Th1 Cells - drug effects | Atherosclerosis - pathology | Phagocytosis - drug effects | Atherosclerosis - immunology | Macrophages - pathology | Aortic Diseases - immunology | Atherosclerosis - chemically induced | Cells, Cultured | Membrane Proteins - immunology | Hepatitis A Virus Cellular Receptor 1 | Plaque, Atherosclerotic | Atherosclerosis - metabolism | Mice, Knockout | Aortic Diseases - genetics | T-Lymphocytes, Regulatory - drug effects | Animals | Membrane Proteins - antagonists & inhibitors | Signal Transduction - drug effects | Lymphocyte Activation - drug effects | Macrophages - drug effects | Cell Proliferation - drug effects | CD4-Positive T-Lymphocytes - drug effects
Journal Article
Molecular Therapy - Nucleic Acids, ISSN 2162-2531, 12/2019, Volume 18, pp. 638 - 649
We have previously shown that third-generation antisense (3GA) inhibition of 14q32 microRNA (miRNA)-494 reduced early development of atherosclerosis. However,... 
Journal Article
Molecular Immunology, ISSN 0161-5890, 12/2010, Volume 48, Issue 1-3, pp. 137 - 146
It is well established that naive cells can be converted by TGF- beta into CD4 super(+)CD25 super(+) regulatory T (Treg) cells with therapeutic potentials.... 
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 06/2017
OBJECTIVE—Inflammasomes are multiprotein complexes, and their activation has been associated with cardiovascular disease. Inflammasome activation leads to... 
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 10/2014, Volume 18, Issue 10, pp. 2020 - 2030
Journal Article
Cardiovascular Research, ISSN 0008-6363, 03/2019, Volume 115, Issue 4, pp. 729 - 738
Abstract Aims T lymphocytes play an important role in atherosclerosis development, but the role of the CD8+ T-cell remains debated, especially in the... 
T-cells | Inflammation | CD8 | Atherosclerosis | APOPTOSIS | CYTOKINES | CARDIAC & CARDIOVASCULAR SYSTEMS | SUBSETS | DEATH | CD8(+) T-cells | ASSOCIATION | EXPRESSION
Journal Article
Cardiovascular Research, ISSN 0008-6363, 08/2016, Volume 111, Issue 3, pp. 252 - 261
Journal Article
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 3/2016, Volume 36, Issue 3, pp. 456 - 465
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 12/2015, Volume 35, Issue 12, pp. 2526 - 2535
OBJECTIVE—Innate lymphoid cells (ILCs) are a newly discovered subset of immune cells that promote tissue homeostasis and protect against pathogens. ILCs... 
eosinophils | cytokines | triglycerides | interleukin | Atherosclerosis | atherosclerosis | IMMUNITY | VISCERAL ADIPOSE-TISSUE | COMPLEXES | RESPONSES | INFLAMMATION | REGULATORY T-CELLS | PERIPHERAL VASCULAR DISEASE | DIFFERENTIATION | HEMATOLOGY | Eosinophilia - metabolism | Atherosclerosis - genetics | Homeodomain Proteins - metabolism | Apolipoproteins B - blood | Aorta - metabolism | Aortic Diseases - metabolism | Interleukin-5 - antagonists & inhibitors | Lymphocytes - immunology | Receptors, LDL - deficiency | Aortic Diseases - prevention & control | Female | Aortic Diseases - pathology | Disease Models, Animal | Interleukin-2 Receptor alpha Subunit - immunology | Lymphocytes - metabolism | Receptors, LDL - genetics | Atherosclerosis - pathology | Atherosclerosis - immunology | Immunity, Innate - drug effects | Aortic Diseases - immunology | Aorta - drug effects | Mice, Inbred C57BL | Aorta - immunology | Biomarkers - blood | Cholesterol, VLDL - blood | Atherosclerosis - metabolism | Homeodomain Proteins - genetics | Interleukin-5 - blood | Mice, Knockout | Antibodies - pharmacology | Aorta - pathology | Interleukin-5 - immunology | Aortic Diseases - genetics | Animals | Eosinophilia - immunology | Interleukin-2 Receptor alpha Subunit - metabolism | Lymphocytes - drug effects | Triglycerides - blood | Eosinophilia - prevention & control | Interleukin-2 - pharmacology | Cell Proliferation - drug effects | Atherosclerosis - prevention & control | Innate lymphoid cells | IL-5 | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Immunologi inom det medicinska området | Immunology in the medical area
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, p. e83134
Objective: Co-stimulatory and co-inhibitory molecules are mainly expressed on T cells and antigen presenting cells and strongly orchestrate adaptive immune... 
IMMUNE | ATHEROGENESIS | INFLAMMATORY MECHANISMS | DENDRITIC CELLS | MULTIDISCIPLINARY SCIENCES | CD226 | NECTIN | Spleen - immunology | Cricetulus | Atherosclerosis - genetics | Dendritic Cells - immunology | Dendritic Cells - pathology | Spleen - drug effects | CD4-Positive T-Lymphocytes - pathology | CD4-Positive T-Lymphocytes - immunology | Receptors, Immunologic - agonists | Receptors, LDL - deficiency | Immunoglobulin G - pharmacology | Dendritic Cells - drug effects | Female | Receptors, Immunologic - immunology | Spleen - pathology | Receptors, LDL - genetics | Atherosclerosis - pathology | Atherosclerosis - immunology | Receptors, LDL - immunology | Mice, Knockout | Antibodies - pharmacology | Animals | Lymphocyte Activation - drug effects | Interleukin-10 - genetics | Cell Proliferation - drug effects | Mice | Receptors, Immunologic - genetics | Interleukin-10 - immunology | CD4-Positive T-Lymphocytes - drug effects | Dendritic cells | T cells | Cardiovascular diseases | Health aspects | Immunoglobulin G | Atherosclerosis | Laboratories | Activation | Lymphocytes T | Biology | Cell activation | Immunology | Lymphocytes | Rodents | Cell cycle | Lipoprotein (low density) receptors | Heart diseases | Immune system | Spleen | Antigens | Immune response | T cell receptors | Thrombosis | CD4 antigen | Signaling | Antigen-presenting cells | Arteriosclerosis | Interleukin 10 | Binding sites
Journal Article
Journal Article