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Nature, ISSN 0028-0836, 11/2015, Volume 527, Issue 7578, pp. 323 - 328
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2013, Volume 288, Issue 37, pp. 26926 - 26943
Journal Article
Nature communications, 05/2017, Volume 8, p. 15779
This corrects the article DOI: 10.1038/ncomms14234. 
Journal Article
Physical Therapy, ISSN 0031-9023, 10/2019
Abstract Background People after stroke benefit from comprehensive programs for the prevention of secondary effects, including cardiac rehabilitation (CR), yet... 
Journal Article
by Al-Shahi Salman, Rustam and Minks, David P and Minks, David and Mitra, Dipayan and Rodrigues, Mark A and Bhatnagar, Priya and du Plessis, Johannes and du Plessis, Johann C and Joshi, Yogish and Dennis, Martin S and Dennis, Martin and Murray, Gordon D and Newby, David E and Sandercock, Peter A G and Sprigg, Nikola and Stephen, Jacqueline and Sudlow, Cathie and Sudlow, Cathie L M and Werring, David and Werring, David J and Whiteley, William N and Whiteley, William and Wardlaw, Joanna M and White, Julie and White, Philip M and White, James and White, Susan and Baigent, Colin and Lasserson, Daniel and Sullivan, Frank and Carrie, Johanna and Rojas, Javier and Amoils, Shannon and Bamford, John and Armitage, Jane and Rinkel, Gabriel and Lowe, Gordon and Emberson, Jonathan and Innes, Karen and Dinsmore, Lynn and Drever, Jonathan and Williams, Rebecca and Williams, Carol and Perry, David and Perry, Jack and McGill, Connor and Buchanan, David and Walker, Susannah and Walker, Marion and Walker, Pauli and Walker, Allan and Hutchison, Aidan and Matthews, Christopher and Fraser, Ruth and McGrath, Aileen and Deary, Ann and Anderson, Rosemary and Hansen, Christian and Parker, Richard and Rodriguez, Aryelly and Macleod, Malcolm and Gattringer, Thomas and Palmer, Jeb and Sakka, Eleni and Adil-Smith, Jennifer and Lerpiniere, Christine and O'Brien, Eoin and O'Brien, Richard and Burgess, Seona and Burgess, Laura and Mead, Denise and Mead, Gillian and Paulton, Ruth and Doubal, Fergus and McCormick, Katrina and Hunter, Neil and Hunter, Annemarie and Taylor, Vicky and Taylor, Pat and Parakramawansha, Ruwan and Blair, Caroline and Blair, Gordon and MacRaild, Allan and Parry-Jones, Adrian and Johnes, Mary and Lee, Stephanie and Shaw, Louise and Shaw, Kelly Marie and Burger, Ilse and Punter, Martin and Ingham, Andrea and Perez, Jane and Naing, Zin and Morell, Jordi and Marsden, Tracy and Hall, Andrea and Marshall, Sally and Harrison, Thomas and Harrison, Melanie and Harrison, Louise and ... and RESTART Collaboration
The Lancet Neurology, ISSN 1474-4422, 07/2019, Volume 18, Issue 7, pp. 643 - 652
Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared... 
MICROBLEEDS | SUPERFICIAL SIDEROSIS | SIGNS | AMYLOID ANGIOPATHY | ACUTE ISCHEMIC-STROKE | ANTITHROMBOTIC THERAPY | ASPIRIN | CLINICAL NEUROLOGY | Atrophy | Neuroimaging | Anticoagulants | Stroke | Aspirin | Statistical analysis | Medical imaging | Magnetic resonance imaging | Computed tomography | Biomarkers | Hemorrhage
Journal Article
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 2019
The kinase RIP1 acts in multiple signaling pathways to regulate inflammatory responses and it can trigger both apoptosis and necroptosis. Its kinase activity... 
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 07/2016, Volume 59, Issue 14, pp. 6671 - 6689
Over the past decade, first and second generation EGFR inhibitors have significantly improved outcomes for lung cancer patients with activating mutations in... 
GROWTH-FACTOR RECEPTOR | IRREVERSIBLE INHIBITORS | IN-VITRO | GEFITINIB | CHEMISTRY, MEDICINAL | METHIONINE MUTANT | BIOLOGICAL EVALUATION | TYROSINE KINASE INHIBITOR | DRUG-RESISTANCE | MUTATIONS | THREONINE | Lung Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - genetics | Rats, Wistar | Antineoplastic Agents - chemical synthesis | Humans | Molecular Conformation | Crystallography, X-Ray | Lung Neoplasms - pathology | Male | Structure-Activity Relationship | Benzimidazoles - chemistry | Nicotine - pharmacology | Dose-Response Relationship, Drug | Neoplasms, Experimental - pathology | Protein Kinase Inhibitors - chemistry | Receptor, Epidermal Growth Factor - metabolism | Antineoplastic Agents - pharmacology | Carcinoma, Non-Small-Cell Lung - pathology | Protein Kinase Inhibitors - chemical synthesis | Lung Neoplasms - enzymology | Benzimidazoles - chemical synthesis | Models, Molecular | Rats | Antineoplastic Agents - chemistry | Drug Discovery | Animals | Nicotine - chemical synthesis | Mice, Nude | Nicotine - analogs & derivatives | Nicotine - chemistry | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Benzimidazoles - pharmacology | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Protein Kinase Inhibitors - pharmacology | Carcinoma, Non-Small-Cell Lung - drug therapy | Carcinoma, Non-Small-Cell Lung - enzymology | Mutation | Neoplasms, Experimental - drug therapy | Drug Screening Assays, Antitumor | Index Medicus
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 06/2019, Volume 29, Issue 12, pp. 1497 - 1501
Receptor-interacting protein kinase 1 (RIPK1), a key component of the cellular necroptosis pathway, has gained recognition as an important therapeutic target.... 
Metabolic stability | Pentafluoroethyl | RIPK1 | Necroptosis | RIPK1 inhibitor | RIP KINASES | HOMEOSTASIS | CHEMISTRY, MEDICINAL | INFLAMMATION | CHEMISTRY, ORGANIC | HIGHLY POTENT | DISCOVERY | International trade | Protein kinases | Analysis
Journal Article
Journal Article