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Methods in Molecular Biology, ISSN 1064-3745, 03/2018, Volume 1732, pp. 363 - 371
AMP-activated protein kinase (AMPK) is a master regulator of multiple cellular metabolic pathways, including lipid metabolism. Some of the well-known... 
Life Sciences | Human health and pathology | Endocrinology and metabolism
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2018, Volume 1732, pp. 363 - 371
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 07/2010, Volume 120, Issue 7, pp. 2355 - 2369
Metformin is widely used to treat hyperglycemia in individuals with type 2 diabetes. Recently the LKB1/AMP-activated protein kinase (LKB1/AMPK) pathway was... 
MEDICINE, RESEARCH & EXPERIMENTAL | RESPIRATORY-CHAIN | SKELETAL-MUSCLE | PHOSPHOENOLPYRUVATE CARBOXYKINASE | ACTIVATED PROTEIN-KINASE | GLUCOKINASE TRANSLOCATION | GLUCOSE-METABOLISM | COACTIVATOR TORC2 | AICA RIBOSIDE | UPSTREAM KINASE | ISOLATED RAT HEPATOCYTES | Glucose-6-Phosphatase - genetics | Hypoglycemic Agents - metabolism | Diabetes Mellitus, Type 2 - genetics | Gluconeogenesis - drug effects | Diabetes Mellitus, Type 2 - metabolism | Hepatocytes - metabolism | Metformin - metabolism | AMP-Activated Protein Kinases | Hyperglycemia - genetics | Liver - drug effects | Protein-Serine-Threonine Kinases - metabolism | Liver - metabolism | Metformin - pharmacology | Mice, Inbred C57BL | Protein-Serine-Threonine Kinases - genetics | Glucose - genetics | Glucose - pharmacology | Glucose-6-Phosphatase - metabolism | Hypoglycemic Agents - pharmacology | Mice, Knockout | Hyperglycemia - metabolism | Phosphoenolpyruvate Carboxykinase (ATP) - genetics | Up-Regulation - drug effects | Animals | Gluconeogenesis - genetics | Glucose-6-Phosphatase - biosynthesis | Phosphoenolpyruvate Carboxykinase (ATP) - metabolism | Glucose - metabolism | Mice | Protein-Serine-Threonine Kinases - pharmacology | Type 2 diabetes | Control | Usage | Genetic aspects | Research | Metformin | Gene expression | Drug therapy | Health aspects | Gluconeogenesis | Up-Regulation | Glucose-6-Phosphatase | gluconeogenesis, animal models | Liver | Protein-Serine-Threonine Kinases | Glucose | LKB1 | Life Sciences | Hypoglycemic Agents | Phosphoenolpyruvate Carboxykinase (ATP) | Human health and pathology | Hyperglycemia | Hepatocytes | AMPK | Endocrinology and metabolism | Diabetes Mellitus, Type 2
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, p. e81870
Modulation of mitochondrial function through inhibiting respiratory complex I activates a key sensor of cellular energy status, the 5'-AMP-activated protein... 
RESPIRATORY-CHAIN | SKELETAL-MUSCLE | METFORMIN ACTION | CELLS | MECHANISM | PROTEIN-KINASE | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | FATTY-ACID | SOLEUS MUSCLE | LIVER | AMP-Activated Protein Kinases - metabolism | Mitochondria, Liver - pathology | Muscle Cells - pathology | Mitochondria, Liver - metabolism | Amino Acids, Branched-Chain - metabolism | Humans | Metformin - pharmacology | Muscle Cells - metabolism | Enzyme Activation - drug effects | Hep G2 Cells | Hypoglycemic Agents - pharmacology | Animals | Palmitates - pharmacology | Oxidation-Reduction - drug effects | Diabetes Mellitus, Experimental - pathology | Glucose - metabolism | Mice | Protein Kinase Inhibitors - pharmacology | Diabetes Mellitus, Experimental - metabolism | Fatty Acids - metabolism | Glucose metabolism | Metabolites | Branched chain amino acids | Analysis | Muscles | Oxidation-reduction reaction | Models | Glucose | Fatty acids | Dextrose | Animal models | Adipose tissue | Liver | Carbon dioxide | Homeostasis | Chain branching | Amino acids | Kinases | AMP-activated protein kinase | Palmitic acid | Electron transport chain | Mitochondria | Animal tissues | Nutrients | Oxidation | Inhibition | Lipogenesis | Cardiology | AMP | Diabetes mellitus | Metabolism | Nutrient uptake | Substrates | Skeletal muscle | Medicine | Energy balance | Musculoskeletal system | Hepatocytes | Insulin resistance | In vivo methods and tests | Catabolism | Gastrointestinal surgery | Metformin | Diabetes | Tracers | Pharmaceuticals
Journal Article
Nature Reviews Endocrinology, ISSN 1759-5029, 07/2015, Volume 11, Issue 7, pp. 390 - 392
Journal Article
NATURE REVIEWS ENDOCRINOLOGY, ISSN 1759-5029, 10/2019, Volume 15, Issue 10, pp. 569 - 589
Journal Article