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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 06/2018, Volume 115, Issue 23, pp. 5986 - 5991
Journal Article
Journal of Computational Physics, ISSN 0021-9991, 09/2016, Volume 321, pp. 932 - 946
We present an efficient computational method for the study of populations of noisy coupled oscillators. By taking a population density approach in which the... 
Stochastic simulation | Particle method | Coupled oscillators | Population density approach | MITOTIC OSCILLATOR | CONVECTION-DIFFUSION EQUATIONS | POPULATIONS | CASCADE | NETWORKS | PHYSICS, MATHEMATICAL | WEIGHTED PARTICLE METHOD | SYNCHRONIZATION | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS | MODELS | NEURONS | VELOCITY METHOD
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 06/2018, Volume 115, Issue 23, p. 5986
Multisite phosphorylation of the PERIOD 2 (PER2) protein is the key step that determines the period of the mammalian circadian clock. Previous studies... 
Circadian rhythms | Biodegradation | Alternative splicing | Phosphorylation | E protein | Algae | Casein kinase I | Priming | Circadian rhythm | Kinases | Proteins | Casein | Robustness (mathematics) | Protein kinase | Diabetes | Period 2 protein | Cancer
Journal Article
Proceedings of the National Academy of Sciences of the United States, ISSN 0027-8424, 06/2018, Volume 115, Issue 23, p. 5986
Multisite phosphorylation of the PERIOD 2 (PER2) protein is the key step that determines the period of the mammalian circadian clock. Previous studies... 
Circadian rhythms | Physiological aspects | Observations | Protein kinases
Journal Article
PLoS Computational Biology, ISSN 1553-734X, 04/2014, Volume 10, Issue 4
  Jet lag arises from a misalignment of circadian biological timing with the timing of human activity, and is caused by rapid transmeridian travel. Jet lag's... 
Mathematical models | Circadian rhythm | Light | Biological clocks
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 07/2015, Volume 112, Issue 29, p. E3911
  The suprachiasmatic nuclei (SCN), the central circadian pacemakers in mammals, comprise a multiscale neuronal system that times daily events. We use recent... 
Signal transduction | Brain | Neurons | Circadian rhythm | Neuropsychology | Mammals | Molecular biology
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 07/2015, Volume 112, Issue 29, p. E3920
  The mammalian suprachiasmatic nucleus (SCN) forms not only the master circadian clock but also a seasonal clock. This neural network of ~10,000 circadian... 
Signal transduction | Neurons | Genetics | Physiology | Circadian rhythm | Neuropsychology | Gene expression
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 07/2015, Volume 112, Issue 29, pp. E3920 - E3920
The mammalian suprachiasmatic nucleus (SCN) forms not only the master circadian clock but also a seasonal clock. This neural network of ~10,000 circadian... 
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 07/2015, Volume 112, Issue 29, pp. E3911 - E3911
The suprachiasmatic nuclei (SCN), the central circadian pacemakers in mammals, comprise a multiscale neuronal system that times daily events. We use recent... 
Journal Article
Journal of Theoretical Biology, ISSN 0022-5193, 05/2015, Volume 373, p. 132
Journal Article
Journal Article
Molecular Systems Biology, ISSN 1744-4292, 2012, Volume 8, Issue 1, pp. 1 - n/a
Journal Article
Journal of Biological Rhythms, ISSN 0748-7304, 02/2013, Volume 28, Issue 1, p. 69
  An internal circadian clock regulates the electrical activity of cardiac myocytes controlling the expression of potassium channel interacting protein-2... 
Cardiac arrhythmia | Electrocardiography | Cardiomyocytes | Circadian rhythm | Potassium | Biological clocks
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2011, Volume 108, Issue 11, p. 4281
Many biochemical events within a cell need to be timed properly to occur at specific times of day, after other events have happened within the cell or in... 
Signal transduction | Biochemistry | Circadian rhythm | Cells | Nonnative species
Journal Article
Journal of Theoretical Biology, ISSN 0022-5193, 05/2015, Volume 373, pp. 132 - 132
Journal Article
Journal Article
PLoS Computational Biology, ISSN 1553-734X, 08/2013, Volume 9, Issue 8
  Hyperexcited states, including depolarization block and depolarized low amplitude membrane oscillations (DLAMOs), have been observed in neurons of the... 
Mathematical models | Circadian rhythm | Grants | Gene expression | Neurons | Potassium
Journal Article
PLoS Computational Biology, ISSN 1553-734X, 2014, Volume 10, Issue 4, p. e1003523
Journal Article
PLoS Computational Biology, ISSN 1553-734X, 07/2011, Volume 7, Issue 7
  An important problem in neuronal computation is to discern how features of stimuli control the timing of action potentials. One aspect of this problem is to... 
Studies | Neurosciences | Neurons | Calculus | Mathematical models | Experiments | Methods
Journal Article
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