X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (30) 30
animals (29) 29
mice (24) 24
dependovirus - genetics (17) 17
genetics & heredity (17) 17
disease models, animal (15) 15
gene therapy (15) 15
biotechnology & applied microbiology (14) 14
male (14) 14
neurons (14) 14
medicine, research & experimental (13) 13
accessories, closures, or fittings therefor (11) 11
containers for storage or transport of articles or materials,e.g. bags, barrels, bottles, boxes, cans, cartons, crates,drums, jars, tanks, hoppers, forwarding containers (11) 11
conveying (11) 11
female (11) 11
handling thin or filamentary material (11) 11
humans (11) 11
packages (11) 11
packaging elements (11) 11
packing (11) 11
performing operations (11) 11
storing (11) 11
transporting (11) 11
article (9) 9
motor neurons - metabolism (9) 9
apparatus or methods for oral or dental hygiene (8) 8
dentistry (8) 8
gene transfer techniques (8) 8
human necessities (8) 8
hygiene (8) 8
medical or veterinary science (8) 8
mice, transgenic (8) 8
amyotrophic-lateral-sclerosis (7) 7
biochemistry & molecular biology (7) 7
genetic therapy (7) 7
genetic vectors - administration & dosage (7) 7
mouse model (7) 7
muscular atrophy, spinal - metabolism (7) 7
neurons - metabolism (7) 7
research (7) 7
amyotrophic lateral sclerosis (6) 6
amyotrophic lateral sclerosis - pathology (6) 6
animals, newborn (6) 6
astrocytes - metabolism (6) 6
brain (6) 6
disease progression (6) 6
genetics (6) 6
green fluorescent proteins - metabolism (6) 6
muscular atrophy, spinal - genetics (6) 6
nervous system (6) 6
nervous system diseases (6) 6
neurosciences (6) 6
rodents (6) 6
survival (6) 6
survival of motor neuron 1 protein - genetics (6) 6
transduction, genetic (6) 6
usage (6) 6
aav9 (5) 5
articles (5) 5
central-nervous-system (5) 5
disease (5) 5
drug discovery (5) 5
gene-transfer (5) 5
general tagging of cross-sectional technologies spanning over several sections of the ipc (5) 5
general tagging of new technological developments (5) 5
genetic therapy - methods (5) 5
genetic vectors (5) 5
green fluorescent proteins - genetics (5) 5
immunohistochemistry (5) 5
macaca fascicularis (5) 5
molecular biology (5) 5
molecular medicine (5) 5
motor-neurons (5) 5
neuroglia - metabolism (5) 5
original (5) 5
pharmacology (5) 5
spinal muscular-atrophy (5) 5
superoxide dismutase - genetics (5) 5
survival of motor neuron 1 protein - metabolism (5) 5
technical subjects covered by former us classification (5) 5
technical subjects covered by former uspc (5) 5
technical subjects covered by former uspc cross-reference art collections [xracs] and digests (5) 5
adeno-associated virus (4) 4
adult mice (4) 4
amyotrophic lateral sclerosis - genetics (4) 4
astrocytes (4) 4
brain - metabolism (4) 4
cardiac defects (4) 4
care and treatment (4) 4
expression (4) 4
gene expression (4) 4
gene expression regulation (4) 4
genetic aspects (4) 4
genetic vectors - genetics (4) 4
motor neurons - pathology (4) 4
muscular atrophy, spinal - therapy (4) 4
mutation (4) 4
neuroglia - pathology (4) 4
neuroscience (4) 4
spinal cord - metabolism (4) 4
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Nature, ISSN 0028-0836, 07/2011, Volume 475, Issue 7357, pp. 497 - 500
Journal Article
NATURE BIOTECHNOLOGY, ISSN 1087-0156, 09/2011, Volume 29, Issue 9, pp. 824 - U79
Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease, with astrocytes implicated as contributing substantially to motor neuron death in familial... 
PLURIPOTENT STEM-CELLS | WILD-TYPE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | DISEASE | EXTEND SURVIVAL | MICE | AMYOTROPHIC-LATERAL-SCLEROSIS | MODEL | BRAIN | PROGRESSION | SOD1 | Physiological aspects | Superoxide | Poisoning | Research | Neurons | Risk factors
Journal Article
Journal Article
Journal Article
Nature Biotechnology, ISSN 1087-0156, 03/2010, Volume 28, Issue 3, pp. 271 - 274
Journal Article
Neuron, ISSN 0896-6273, 07/2015, Volume 87, Issue 2, pp. 355 - 370
One pathological hallmark in ALS motor neurons (MNs) is axonal accumulation of damaged mitochondria. A fundamental question remains: does reduced degradation... 
RETROGRADE TRANSPORT | DELAYS PROGRESSION | MOUSE MODEL | IN-VIVO | LINKED SOD1 MUTANTS | AXONAL-TRANSPORT | AMYOTROPHIC-LATERAL-SCLEROSIS | LITHIUM-CARBONATE | LYSOSOMAL STORAGE DISORDERS | NEUROSCIENCES | TRANSGENIC MICE | Neurons - pathology | Superoxide Dismutase - genetics | Age Factors | Humans | Membrane Potential, Mitochondrial - drug effects | Autophagy | Amyotrophic Lateral Sclerosis - drug therapy | Vesicular Transport Proteins - therapeutic use | DNA-Binding Proteins - metabolism | Neurons - ultrastructure | Time Factors | Spinal Cord - pathology | Membrane Potential, Mitochondrial - genetics | Lysosomes - pathology | Neurons - drug effects | Nuclear Proteins - genetics | Disease Models, Animal | Transduction, Genetic | Gene Expression Regulation - genetics | Amyotrophic Lateral Sclerosis - genetics | Cells, Cultured | Mice, Transgenic | Nuclear Proteins - metabolism | Mitochondria - pathology | DNA-Binding Proteins - genetics | Disease Progression | Amyotrophic Lateral Sclerosis - pathology | Animals | Mice | Amyotrophic lateral sclerosis | Nervous system diseases | Neurosciences | Mitochondrial DNA | Neurons | Dynein | Pathology | Mitochondria | Hypotheses | Data analysis | Statistical analysis | Disease | Microscopy | Pathogenesis | Rodents | Mutation | Index Medicus | dynein | motor neurons | autophagy | cathepsin D | mitochondria | ALS | axonal transport | neurodegeneration | late endosome | lysosome | SOD1
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 07/2010, Volume 19, Issue 20, pp. 3895 - 3905
Proximal spinal muscular atrophy (SMA) is a debilitating neurological disease marked by isolated lower motor neuron death and subsequent atrophy of skeletal... 
Journal Article
Molecular Therapy, ISSN 1525-0016, 03/2015, Volume 23, Issue 3, pp. 477 - 487
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 2013, Volume 33, Issue 34, pp. 13612 - 13620
Journal Article