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1. Full Text Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol
by Lange, Leslie A and Hu, Youna and Zhang, He and Xue, Chenyi and Schmidt, Ellen M and Tang, Zheng-Zheng and Bizon, Chris and Lange, Ethan M and Smith, Joshua D and Turner, Emily H and Jun, Goo and Kang, Hyun Min and Peloso, Gina and Auer, Paul and Li, Kuo-ping and Flannick, Jason and Zhang, Ji and Fuchsberger, Christian and Gaulton, Kyle and Lindgren, Cecilia and Locke, Adam and Manning, Alisa and Sim, Xueling and Rivas, Manuel A and Holmen, Oddgeir L and Gottesman, Omri and Lu, Yingchang and Ruderfer, Douglas and Stahl, Eli A and Duan, Qing and Li, Yun and Durda, Peter and Jiao, Shuo and Isaacs, Aaron and Hofman, Albert and Bis, Joshua C and Correa, Adolfo and Griswold, Michael E and Jakobsdottir, Johanna and Smith, Albert V and Schreiner, Pamela J and Feitosa, Mary F and Zhang, Qunyuan and Huffman, Jennifer E and Crosby, Jacy and Wassel, Christina L and Do, Ron and Franceschini, Nora and Martin, Lisa W and Robinson, Jennifer G and Assimes, Themistocles L and Crosslin, David R and Rosenthal, Elisabeth A and Tsai, Michael and Rieder, Mark J and Farlow, Deborah N and Folsom, Aaron R and Lumley, Thomas and Fox, Ervin R and Carlson, Christopher S and Peters, Ulrike and Jackson, Rebecca D and van Duijn, Cornelia M and Uitterlinden, André G and Levy, Daniel and Rotter, Jerome I and Taylor, Herman A and Gudnason, Vilmundur and Siscovick, David S and Fornage, Myriam and Borecki, Ingrid B and Hayward, Caroline and Rudan, Igor and Chen, Y. Eugene and Bottinger, Erwin P and Loos, Ruth J.F and Sætrom, Pål and Hveem, Kristian and Boehnke, Michael and Groop, Leif and McCarthy, Mark and Meitinger, Thomas and Ballantyne, Christie M and Gabriel, Stacey B and O’Donnell, Christopher J and Post, Wendy S and North, Kari E and Reiner, Alexander P and Boerwinkle, Eric and Psaty, Bruce M and Altshuler, David and Kathiresan, Sekar and Lin, Dan-Yu and Jarvik, Gail P and Cupples, L. Adrienne and Kooperberg, Charles and Wilson, James G and Nickerson, Deborah A and Abecasis, Goncalo R and Rich, Stephen S and ... and the NHLBI Grand Opportunity Exome Sequencing Project and NHLBI Grand Opportunity Exome Sequ and NHLBI Grand Opportunity Exome Sequencing Project
American journal of human genetics, ISSN 0002-9297, 02/2014, Volume 94, Issue 2, pp. 233 - 245
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Dyslipidemias - genetics | Genetic Code | Follow-Up Studies | Humans | Middle Aged | Male | Proprotein Convertases - genetics | Exome | Dyslipidemias - blood | Serine Endopeptidases - genetics | Adult | Female | Receptors, LDL - genetics | Genome-Wide Association Study | Gene Frequency | Genotype | Sequence Analysis, DNA | Cholesterol, LDL - genetics | Phenotype | Apolipoproteins E - blood | Apolipoproteins E - genetics | Aged | Polymorphism, Single Nucleotide | Cohort Studies | Lipase - genetics | Proprotein Convertase 9 | Genetic code | Genetic variation | Physiological aspects | Genetic research | Cholesterol, LDL | Genetic aspects | Research | Nucleotide sequencing | DNA sequencing | Genotype & phenotype | Low density lipoprotein | Genes | Cholesterol | Risk factors | Index Medicus | Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
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2. Full Text Burden of Rare Sarcomere Gene Variants in the Framingham and Jackson Heart Study Cohorts
by Bick, Alexander G and Flannick, Jason and Ito, Kaoru and Cheng, Susan and Vasan, Ramachandran S and Parfenov, Michael G and Herman, Daniel S and DePalma, Steven R and Gupta, Namrata and Gabriel, Stacey B and Funke, Birgit H and Rehm, Heidi L and Benjamin, Emelia J and Aragam, Jayashri and Taylor, Herman A and Fox, Ervin R and Newton-Cheh, Christopher and Kathiresan, Sekar and O’Donnell, Christopher J and Wilson, James G and Altshuler, David M and Hirschhorn, Joel N and Seidman, J.G and Seidman, Christine
American journal of human genetics, ISSN 0002-9297, 09/2012, Volume 91, Issue 3, pp. 513 - 519
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Molecular and cellular biology | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Medical genetics | Cardiomyopathy, Dilated - genetics | Cardiomyopathy, Hypertrophic - genetics | Models, Cardiovascular | Humans | Middle Aged | Risk Factors | Male | Cardiovascular Diseases - genetics | Genetic Variation | Sarcomeres - genetics | Aged, 80 and over | Adult | Female | Aged | Cohort Studies | Genetic variation | Cardiac patients | Causes of | Genetic aspects | Disease susceptibility | Research | Cardiovascular diseases | Proteins | Cardiovascular disease | Gene expression | Morphology | Cells | Risk factors | Index Medicus | Report
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3. Full Text Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration
by Noordam, R and Bos, M.M and Wang, H and Winkler, Thomas W and Bentley, Amy and Kilpeläinen, T.O and Vries, Paul and Sung, Y.J and Schwander, K and Cade, B and Manning, Alisa and Aschard, Hugues and Brown, M.R and Chen, H and Franceschini, Nora and Musani, S.K and Richard, M and Vojinović, Dina and Aslibekyan, S and Bartz, T.M and de Las Fuentes, L and Feitosa, Mary Furlan and Horimoto, A.R and Ilkov, M and Kho, M and Kraja, Aldi and Li, C and Lim, E and Liu, YongMei and Mook-Kanamori, D.O and Rankinen, Tuomo and Tajuddin, S.M and Spek, Ashley and Wang, Z and Marten, Jonathan and Laville, V and Alver, Maris and Evangelou, Evangelos and Graff, M.E and He, M and Kuhnel, Brigitte and Lyytikäinen, L.-P and Marques-Vidal, Peo and Nolte, Ilja and Palmer, Nicholette and Rauramaa, Rainer and Shu, X.-O and Snieder, Harold and Weiss, S and Wen, W and Yanek, Lisa and Adolfo, C and Ballantyne, Christie and Bielak, Lawrence F and Biermasz, N.R and Boerwinkle, Eric and Dimou, N and Eiriksdottir, Gudny and Gao, C and Gharib, Sina and Gottlieb, D.J and Haba-Rubio, J and Harris, Tamara and Heikkinen, S and Heinzer, R and Hixson, J.E and Homuth, Georg and Ikram, Arfan and Komulainen, P and Krieger, José and Lee, J and Liu, J and Lohman, K.K and Luik, Annemarie and Mägi, Reedik and Martin, Lisa and Meitinger, Thomas and Metspalu, Anes and Milaneschi, Y and Nalls, Michael and O´Connell, J.R and Peters, Annette and Peyser, Patricia A and Raitakari, Olli and Reiner, Alexander and Rensen, Patrick and Rice, Treva K and Rich, Stephen and Roenneberg, T and Rotter, Jerome I and Schreiner, Pamela and Shikany, J and Sidney, S.S and Sims, M and Sitlani, C.M and Sofer, T and Strauch, Konstantin and Swertz, M.A and Taylor, Kent and Uitterlinden, Ané and ...
Nature communications, ISSN 2041-1723, 11/2019, Volume 10, Issue 1, pp. 5121 - 13
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Lipids - genetics | Humans | Middle Aged | Male | Chromosome Mapping | Sleep - genetics | Genetic Loci | Phylogeny | Young Adult | Adolescent | Aged, 80 and over | Polymorphism, Single Nucleotide - genetics | Adult | Female | Aged | Lipoproteins (low density) | Sleep | Lipids | Single-nucleotide polymorphism | Genomes | Triglycerides | Loci | Lipoproteins (high density) | Index Medicus
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4. Full Text LXR/RXR signaling and neutrophil phenotype following myocardial infarction classify sex differences in remodeling
by DeLeon-Pennell, Kristine Y and Mouton, Alan J and Ero, Osasere K and Ma, Yonggang and Padmanabhan Iyer, Rugmani and Flynn, Elizabeth R and Espinoza, Ingrid and Musani, Solomon K and Vasan, Ramachandran S and Hall, Michael E and Fox, Ervin R and Lindsey, Merry L
Basic research in cardiology, ISSN 0300-8428, 9/2018, Volume 113, Issue 5, pp. 1 - 19
Medicine & Public Health | Humans | Neutrophils | Proteomics | Sex differences | Mice | Big data | Cardiology | LXR/RXR | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | United States - epidemiology | Prognosis | Age Factors | Ventricular Function, Left | Middle Aged | Heart Failure - physiopathology | African Americans | Male | Young Adult | Ventricular Remodeling | Myocardial Infarction - pathology | Myocardium - metabolism | Aged, 80 and over | Adult | Female | Myocardial Infarction - physiopathology | Neutrophils - metabolism | Retinoid X Receptors - metabolism | Databases, Factual | Disease Models, Animal | Heart Failure - ethnology | Signal Transduction | Mice, Inbred C57BL | Myocardium - pathology | Heart Failure - metabolism | Liver X Receptors - metabolism | Heart Failure - pathology | Myocardial Infarction - metabolism | Phenotype | Animals | Sex Factors | Aged | Myocardial Infarction - ethnology | Genetic aspects | Interleukins | Gene expression | Heart attack | Myocardial infarction | Heart attacks | Communities | Liver | Interleukin | Sex | Kinases | AMP-activated protein kinase | Interleukin 6 | Proteins | Signal transduction | Receptors | Cell activation | Older people | Gender aspects | Heart diseases | Age | Thrombospondin | Heart failure | Women | NF-κB protein | Phenotypes | Wound healing | Desensitization | AMP | Liver X receptors | Leukocytes (neutrophilic) | Gender differences | Inflammation | CD36 antigen | Retinoid X receptors | Apolipoproteins | Signaling | Men | Infarction | Adults | Peroxisome proliferator-activated receptors | Females | Index Medicus | LXR | Original Contribution | RXR
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5. Full Text Genome-wide Association Analysis of Blood-Pressure Traits in African-Ancestry Individuals Reveals Common Associated Genes in African and Non-African Populations
by Franceschini, Nora and Fox, Ervin and Zhang, Zhaogong and Edwards, Todd L and Nalls, Michael A and Sung, Yun Ju and Tayo, Bamidele O and Sun, Yan V and Gottesman, Omri and Adeyemo, Adebawole and Johnson, Andrew D and Young, J. Hunter and Rice, Ken and Duan, Qing and Chen, Fang and Li, Yun and Tang, Hua and Fornage, Myriam and Keene, Keith L and Andrews, Jeanette S and Smith, Jennifer A and Faul, Jessica D and Guangfa, Zhang and Guo, Wei and Liu, Yu and Murray, Sarah S and Musani, Solomon K and Srinivasan, Sathanur and Velez Edwards, Digna R and Wang, Heming and Becker, Lewis C and Bovet, Pascal and Bochud, Murielle and Broeckel, Ulrich and Burnier, Michel and Carty, Cara and Chasman, Daniel I and Ehret, Georg and Chen, Wei-Min and Chen, Guanjie and Chen, Wei and Ding, Jingzhong and Dreisbach, Albert W and Evans, Michele K and Guo, Xiuqing and Garcia, Melissa E and Jensen, Rich and Keller, Margaux F and Lettre, Guillaume and Lotay, Vaneet and Martin, Lisa W and Moore, Jason H and Morrison, Alanna C and Mosley, Thomas H and Ogunniyi, Adesola and Palmas, Walter and Papanicolaou, George and Penman, Alan and Polak, Joseph F and Ridker, Paul M and Salako, Babatunde and Singleton, Andrew B and Shriner, Daniel and Taylor, Kent D and Vasan, Ramachandran and Wiggins, Kerri and Williams, Scott M and Yanek, Lisa R and Zhao, Wei and Zonderman, Alan B and Becker, Diane M and Berenson, Gerald and Boerwinkle, Eric and Bottinger, Erwin and Cushman, Mary and Eaton, Charles and Nyberg, Fredrik and Heiss, Gerardo and Hirschhron, Joel N and Howard, Virginia J and Karczewsk, Konrad J and Lanktree, Matthew B and Liu, Kiang and Liu, Yongmei and Loos, Ruth and Margolis, Karen and Snyder, Michael and Go, Min Jin and Kim, Young Jin and Lee, Jong-Young and Jeon, Jae-Pil and Kim, Sung Soo and Han, Bok-Ghee and Cho, Yoon Shin and Sim, Xueling and Tay, Wan Ting and Ong, Rick Twee Hee and Seielstad, Mark and Liu, Jian Jun and Aung, Tin and ... and the Asian Genetic Epidemiology Network Consortium and Asian Genetic Epidemiology Network and Asian Genetic Epidemiology Network Consortium
American journal of human genetics, ISSN 0002-9297, 09/2013, Volume 93, Issue 3, pp. 545 - 554
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetic Predisposition to Disease | Genome-Wide Association Study | Reproducibility of Results | Quantitative Trait, Heritable | Blood Pressure - genetics | Humans | Africa | Genetic Loci - genetics | Databases, Genetic | Polymorphism, Single Nucleotide - genetics | African Continental Ancestry Group - genetics | Cohort Studies | Quantitative genetics | Genome-wide association studies | Physiological aspects | Blood pressure | Genetic aspects | Research | Population genetics | Cardiovascular disease | Genomes | Minority & ethnic groups | Meta-analysis | Index Medicus | Report
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6. Full Text Meta-analysis of Correlated Traits via Summary Statistics from GWASs with an Application in Hypertension
by Zhu, Xiaofeng and Feng, Tao and Tayo, Bamidele O and Liang, Jingjing and Young, J. Hunter and Franceschini, Nora and Smith, Jennifer A and Yanek, Lisa R and Sun, Yan V and Edwards, Todd L and Chen, Wei and Nalls, Mike and Fox, Ervin and Sale, Michele and Bottinger, Erwin and Rotimi, Charles and Liu, Yongmei and McKnight, Barbara and Liu, Kiang and Arnett, Donna K and Chakravati, Aravinda and Cooper, Richard S and Redline, Susan and The COGENT BP Consortium and COGENT BP Consortium
American journal of human genetics, ISSN 0002-9297, 01/2015, Volume 96, Issue 1, pp. 21 - 36
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genome-Wide Association Study | Phenotype | Blood Pressure - genetics | Models, Biological | Humans | Polymorphism, Single Nucleotide | Genetic Loci | Hypertension - genetics | Quantitative trait loci | Hypertension | Genome-wide association studies | Genetic aspects | Research | Simulation | Correlation analysis | Statistics | Genomics | Meta-analysis | Index Medicus
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