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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2014, Volume 111, Issue 28, pp. 10371 - 10376
Journal Article
by Akbarian, Schahram and Liu, Chunyu and Knowles, James A and Vaccarino, Flora M and Farnham, Peggy J and Crawford, Gregory E and Jaffe, Andrew E and Pinto, Dalila and Dracheva, Stella and Geschwind, Daniel H and Mill, Jonathan and Nairn, Angus C and Abyzov, Alexej and Pochareddy, Sirisha and Prabhakar, Shyam and Weissman, Sherman and Sullivan, Patrick F and State, Matthew W and Weng, Zhiping and Peters, Mette A and White, Kevin P and Gerstein, Mark B and Amiri, Anahita and Armoskus, Chris and Ashley-Koch, Allison E and Bae, Taejeong and Beckel-Mitchener, Andrea and Berman, Benjamin P and Coetzee, Gerhard A and Coppola, Gianfilippo and Francoeur, Nancy and Fromer, Menachem and Gao, Robert and Grennan, Kay and Herstein, Jennifer and Kavanagh, David H and Ivanov, Nikolay A and Jiang, Yan and Kitchen, Robert R and Kozlenkov, Alexey and Kundakovic, Marija and Li, Mingfeng and Li, Zhen and Liu, Shuang and Mangravite, Lara M and Mattei, Eugenio and Markenscoff-Papadimitriou, Eirene and Navarro, Fábio C.P and North, Nicole and Omberg, Larsson and Panchision, David and Parikshak, Neelroop and Poschmann, Jeremie and Price, Amanda J and Purcaro, Michael and Reddy, Timothy E and Roussos, Panos and Schreiner, Shannon and Scuderi, Soraya and Sebra, Robert and Shibata, Mikihito and Shieh, Annie W and Skarica, Mario and Sun, Wenjie and Swarup, Vivek and Thomas, Amber and Tsuji, Junko and Van Bakel, Harm and Wang, Daifeng and Wang, Yongjun and Wang, Kai and Werling, Donna M and Willsey, A. Jeremy and Witt, Heather and Won, Hyejung and Wong, Chloe C.Y and Wray, Gregory A and Wu, Emily Y and Xu, Xuming and Yao, Lijing and Senthil, Geetha and Lehner, Thomas and Sklar, Pamela and Sestan, Nenad and PsychENCODE Consortium
Nature Neuroscience, ISSN 1097-6256, 11/2015, Volume 18, Issue 12, pp. 1707 - 1712
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2012, Volume 287, Issue 21, pp. 17672 - 17681
TRPC6 is a cation channel in the plasma membrane that plays a role in Ca2+ entry after the stimulation of a G(q)-protein-coupled or tyrosine-kinase receptor.... 
CA2+ ENTRY | CALCIUM-ENTRY | PULMONARY ARTERIAL-HYPERTENSION | PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHANNEL ACTIVATION | PROSTATE-CANCER | TUMOR-SUPPRESSOR | RECEPTOR | PLASMA-MEMBRANE | INTRACELLULAR TRAFFICKING | Muscle, Smooth, Vascular - metabolism | Calcium - metabolism | Calcium Signaling - physiology | Humans | Protein Transport - physiology | Cell Membrane - genetics | Phosphatidylinositol 3-Kinases - metabolism | Protein Transport - drug effects | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | HEK293 Cells | Muscle Proteins - metabolism | Muscle Proteins - antagonists & inhibitors | Cell Membrane - metabolism | Chromones - pharmacology | TRPC Cation Channels - genetics | Myocytes, Smooth Muscle - cytology | Myocytes, Smooth Muscle - metabolism | PTEN Phosphohydrolase - genetics | TRPC6 Cation Channel | Morpholines - pharmacology | PTEN Phosphohydrolase - metabolism | Cardiotonic Agents - pharmacology | Muscle, Smooth, Vascular - cytology | Muscle Proteins - genetics | Phosphatidylinositol 3-Kinases - genetics | Carbachol - pharmacology | Animals | Androstadienes - pharmacology | Calcium Signaling - drug effects | TRPC Cation Channels - metabolism | Mice | Protein Kinase Inhibitors - pharmacology | Signal Transduction | Calcium Channels | TRP Channels | Trafficking | Phosphoinositide 3-Kinase (PI3K) | PTEN | Calcium Signaling
Journal Article
Nature Neuroscience, ISSN 1097-6256, 08/2018, Volume 21, Issue 8, pp. 1126 - 1136
Journal Article
Cancer Research, ISSN 0008-5472, 08/2011, Volume 71, Issue 15, pp. 5081 - 5089
Resistance to platinum-based chemotherapy develops in the majority of patients with epithelial ovarian cancer (EOC). Platinum compounds form electrophilic... 
ELEMENTS | GENE | MECHANISM | ONCOLOGY | DIMERIZATION | IDENTIFICATION | PROTEINS | EXPRESSION | NF-E2-Related Factor 2 - physiology | Adenocarcinoma, Clear Cell - mortality | Humans | Neoplasm Proteins - physiology | Ovarian Neoplasms - pathology | Carcinoma - mortality | Antineoplastic Agents, Alkylating - pharmacology | Neoplasm Proteins - antagonists & inhibitors | Cell Line, Tumor - drug effects | Gene Expression Profiling | Ovarian Neoplasms - mortality | Organoplatinum Compounds - pharmacology | Ovarian Neoplasms - genetics | RNA Interference | DNA Mutational Analysis | Female | NF-E2-Related Factor 2 - genetics | Carcinoma - pathology | Neoplasm Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Kelch-Like ECH-Associated Protein 1 | Ovarian Neoplasms - drug therapy | Carcinoma - drug therapy | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | RNA, Small Interfering - pharmacology | Kaplan-Meier Estimate | Proportional Hazards Models | Signal Transduction - genetics | DNA, Neoplasm - drug effects | Sequence Analysis, DNA | Antineoplastic Agents, Alkylating - therapeutic use | Drug Resistance, Neoplasm - genetics | Carcinoma - genetics | Signal Transduction - physiology | Adenocarcinoma, Clear Cell - pathology | DNA, Neoplasm - genetics | Carboplatin - pharmacology | Intracellular Signaling Peptides and Proteins - physiology | Adenocarcinoma, Clear Cell - genetics | Organoplatinum Compounds - therapeutic use | Adenocarcinoma, Clear Cell - drug therapy
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 09/2017, Volume 377, Issue 12, pp. 1119 - 1131
Patients with myocardial infarction and a high-sensitivity CRP level of 2 mg or more per liter were assigned to one of three canakinumab doses or placebo. The... 
C-REACTIVE PROTEIN | MEDICINE, GENERAL & INTERNAL | HEART-DISEASE | MYOCARDIAL-INFARCTION | STATIN THERAPY | CLONAL HEMATOPOIESIS | INFLAMMATION | CARDIOVASCULAR-DISEASE | INTERLEUKIN-1-BETA INHIBITION | RISK | CORONARY-ARTERY-DISEASE | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Male | Secondary Prevention | Infection - etiology | Incidence | Dose-Response Relationship, Drug | Anti-Inflammatory Agents - adverse effects | C-Reactive Protein - metabolism | Lipids - blood | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Anti-Inflammatory Agents - administration & dosage | Female | Neutropenia - chemically induced | Interleukin-1beta - antagonists & inhibitors | Stroke - prevention & control | Atherosclerosis - drug therapy | Double-Blind Method | Interleukin-1beta - immunology | Atherosclerosis - blood | Myocardial Infarction - drug therapy | Antibodies, Monoclonal - administration & dosage | Aged | Myocardial Infarction - prevention & control | Myocardial infarction | Cerebral infarction | Stroke | Heart attacks | C-reactive protein | Cytokines | Clinical trials | Cardiovascular disease | Innate immunity | Inflammation | Angina | Angina pectoris | Thrombosis | Cholesterol | Disease prevention | Proteins | Arteriosclerosis | Atherosclerosis | Cardiovascular diseases | Health risk assessment | Drug therapy | Drug dosages | Klinisk medicin | Clinical Medicine
Journal Article