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1. Full Text Evidence for Network Evolution in an "Arabidopsis" Interactome Map
by Braun, Pascal and Carvunis, Anne-Ruxandra and Charloteaux, Benoit and Dreze, Matija and Ecker, Joseph R and Hill, David E and Roth, Frederick P and Vidal, Marc and Galli, Mary and Balumuri, Padmavathi and Bautista, Vanessa and Chesnut, Jonathan D and Kim, Rosa Cheuk and de los Reyes, Chris and Gilles, Patrick and Kim, Christopher J and Matrubutham, Uday and Mirchandani, Jyotika and Olivares, Eric and Patnaik, Suswapna and Quan, Rosa and Ramaswamy, Gopalakrishna and Shinn, Paul and Swamilingiah, Geetha M and Wu, Stacy and Ecker, Joseph R and Dreze, Matija and Byrdsong, Danielle and Dricot, Amelie and Duarte, Melissa and Gebreab, Fana and Gutierrez, Bryan J and MacWilliams, Andrew and Monachello, Dario and Mukhtar, M. Shahid and Poulin, Matthew M and Reichert, Patrick and Romero, Viviana and Tam, Stanley and Waaijers, Selma and Weiner, Evan M and Vidal, Marc and Hill, David E and Braun, Pascal and Galli, Mary and Carvunis, Anne-Ruxandra and Cusick, Michael E and Dreze, Matija and Romero, Viviana and Roth, Frederick P and Tasan, Murat and Yazaki, Junshi and Braun, Pascal and Ecker, Joseph R and Carvunis, Anne-Ruxandra and Ahn, Yong-Yeol and Barabasi, Albert-Laszlo and Charloteaux, Benoit and Chen, Huaming and Cusick, Michael E and Dangl, Jeffery L and Dreze, Matija and Ecker, Joseph R and Fan, Changyu and Gai, Lantian and Galli, Mary and Ghoshal, Gourab and Hao, Tong and Hill, David E and Lurin, Claire and Milenkovic, Tijana and Moore, Jonathan and Mukhtar, M. Shahid and Pevzner, Samuel J and Przulj, Natasa and Rabello, Sabrina and Rietman, Edward A and Rolland, Thomas and Roth, Frederick P and Santhanam, Balaji and Schmitz, Robert J and Spooner, William and Stein, Joshua and Tasan, Murat and Vandenhaute, Jean and Ware, Doreen and Braun, Pascal and Vidal, Marc and Braun, Pascal and Carvunis, Anne-Ruxandra and Charloteaux, Benoit and Dreze, Matija and Galli, Mary and Vidal, Marc and Arabidopsis Interactome Mapping Co and Arabidopsis Interactome Mapping Consortium
Science (American Association for the Advancement of Science), ISSN 0036-8075, 7/2011, Volume 333, Issue 6042, pp. 601 - 607
Community structure | Proteins | Research fellowships | Medical research | Yeasts | Divergent evolution | RESEARCH ARTICLES | Evolution | Gene duplication | Plants | Protein interaction mapping | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Cell physiology | Plant physiology and development | General aspects, methods | Arabidopsis Proteins - genetics | Signal Transduction | Genes, Plant | Proteome | Arabidopsis - metabolism | Protein Interaction Mapping | 14-3-3 Proteins - metabolism | Arabidopsis - genetics | Arabidopsis Proteins - metabolism | Transcription Factors - metabolism | Ubiquitination | Plant Growth Regulators - metabolism | Evolution, Molecular | Arabidopsis thaliana | Proteomics | Physiological aspects | Genetic aspects | Research | Protein-protein interactions | Index Medicus | Life Sciences | Vegetal Biology
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2. Full Text The Genetic Landscape of a Cell
by Michael Costanzo and Anastasia Baryshnikova and Jeremy Bellay and Yungil Kim and Eric D. Spear and Carolyn S. Sevier and Huiming Ding and Judice L. Y. Koh and Kiana Toufighi and Sara Mostafavi and Jeany Prinz and Robert P. St. Onge and Benjamin VanderSluis and Taras Makhnevych and Franco J. Vizeacoumar and Solmaz Alizadeh and Sondra Bahr and Renee L. Brost and Yiqun Chen and Murat Cokol and Raamesh Deshpande and Zhijian Li and Zhen-Yuan Lin and Wendy Liang and Michaela Marback and Jadine Paw and Bryan-Joseph San Luis and Ermira Shuteriqi and Amy Hin Yan Tong and Nydia van Dyk and Iain M. Wallace and Joseph A. Whitney and Matthew T. Weirauch and Guoqing Zhong and Hongwei Zhu and Walid A. Houry and Michael Brudno and Sasan Ragibizadeh and Balázs Papp and Csaba Pál and Frederick P. Roth and Guri Giaever and Corey Nislow and Olga G. Troyanskaya and Howard Bussey and Gary D. Bader and Anne-Claude Gingras and Quaid D. Morris and Philip M. Kim and Chris A. Kaiser and Chad L. Myers and Brenda J. Andrews and Charles Boone
Science (American Association for the Advancement of Science), ISSN 0036-8075, 1/2010, Volume 327, Issue 5964, pp. 425 - 431
Quantitative genetics | Genetic mapping | Microbial genetics | Gene interaction | Genes | Drug interactions | Medical genetics | Evolutionary genetics | Genetics | Human genetics | Research Article | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Cytogenetics | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Thallophyta, bryophyta | Vegetals and fungi | Gene Duplication | Gene Expression Regulation, Fungal | Saccharomyces cerevisiae - physiology | Saccharomyces cerevisiae - genetics | Computational Biology | Saccharomyces cerevisiae Proteins - genetics | Gene Regulatory Networks | Protein Interaction Mapping | Saccharomyces cerevisiae - metabolism | Genetic Fitness | Genome, Fungal | Metabolic Networks and Pathways | Saccharomyces cerevisiae Proteins - metabolism | Genes, Fungal | Mutation | Evaluation | Chromosome mapping | Pleiotropy | Genetic aspects | Structure | Brewer's yeast | Genotype & phenotype | Yeast | Cellular biology | Genomics | Index Medicus
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3. Full Text Chemical substructures that enrich for biological activity
by Klekota, Justin and Roth, Frederick P
Bioinformatics, ISSN 1367-4803, 11/2008, Volume 24, Issue 21, pp. 2518 - 2525
Statistics & Probability | Biochemistry & Molecular Biology | Physical Sciences | Computer Science, Interdisciplinary Applications | Life Sciences & Biomedicine | Technology | Biochemical Research Methods | Computer Science | Mathematics | Biotechnology & Applied Microbiology | Science & Technology | Mathematical & Computational Biology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | General aspects | Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects) | Animals | Combinatorial Chemistry Techniques | Humans | Cells, Cultured | Drug Design | Pharmaceutical Preparations - chemistry | Ligands | Structure-Activity Relationship | Databases, Factual | Index Medicus | Original Papers
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4. Full Text Multiplexed assays of variant effects contribute to a growing genotype–phenotype atlas
by Weile, Jochen and Roth, Frederick P
Human genetics, ISSN 0340-6717, 9/2018, Volume 137, Issue 9, pp. 665 - 678
Human Genetics | Gene Function | MAVE | Deep mutational scanning | Biomedicine | VUS | Metabolic Diseases | Molecular Medicine | Variants of uncertain significance | Variant effect | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetic Variation | Computational Biology - methods | Phenotype | Humans | Genetic Association Studies - methods | Genotype | Genome, Human | High-Throughput Nucleotide Sequencing - methods | Phenotypes | Genomes | Genotypes | Computer applications | Index Medicus | Review
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5. Full Text A Map of the Interactome Network of the Metazoan C. elegans
by Siming Li and Christopher M. Armstrong and Nicolas Bertin and Hui Ge and Stuart Milstein and Mike Boxem and Pierre-Olivier Vidalain and Jing-Dong J. Han and Alban Chesneau and Tong Hao and Debra S. Goldberg and Ning Li and Monica Martinez and Jean-François Rual and Philippe Lamesch and Lai Xu and Muneesh Tewari and Sharyl L. Wong and Lan V. Zhang and Gabriel F. Berriz and Laurent Jacotot and Philippe Vaglio and Jérôme Reboul and Tomoko Hirozane-Kishikawa and Qianru Li and Harrison W. Gabel and Ahmed Elewa and Bridget Baumgartner and Debra J. Rose and Haiyuan Yu and Stephanie Bosak and Reynaldo Sequerra and Andrew Fraser and Susan E. Mango and William M. Saxton and Susan Strome and Sander van den Heuvel and Fabio Piano and Jean Vandenhaute and Claude Sardet and Mark Gerstein and Lynn Doucette-Stamm and Kristin C. Gunsalus and J. Wade Harper and Michael E. Cusick and Frederick P. Roth and David E. Hill and Marc Vidal
Science (American Association for the Advancement of Science), ISSN 0036-8075, 1/2004, Volume 303, Issue 5657, pp. 540 - 543
Datasets | Transcriptomes | Yeasts | Drug interactions | Genes | Reports | Open reading frames | Protein interaction mapping | Pharynx | Worms | Medical schools | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Intermolecular phenomena | Interactions. Associations | Molecular biophysics | Caenorhabditis elegans - metabolism | Caenorhabditis elegans - genetics | Genomics | Open Reading Frames | Computational Biology | Genes, Helminth | Caenorhabditis elegans Proteins - metabolism | Two-Hybrid System Techniques | Phenotype | Animals | Protein Binding | Transcription, Genetic | Caenorhabditis elegans Proteins - genetics | Proteome - metabolism | Evolution, Molecular | Cell interaction | Protein metabolism | Genetic aspects | Chemical properties | Research | Proteins | Bacteria | Models | Microbiology | proteomics | protein-protein interactions | Index Medicus | Life Sciences | Biochemistry, Molecular Biology
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6. Full Text Independently Evolved Virulence Effectors Converge onto Hubs in a Plant Immune System Network
by M. Shahid Mukhtar and Anne-Ruxandra Carvunis and Matija Dreze and Petra Epple and Jens Steinbrenner and Jonathan Moore and Murat Tasan and Mary Galli and Tong Hao and Marc T. Nishimura and Samuel J. Pevzner and Susan E. Donovan and Lila Ghamsari and Balaji Santhanam and Viviana Romero and Matthew M. Poulin and Fana Gebreab and Bryan J. Gutierrez and Stanley Tam and Dario Monachello and Mike Boxem and Christopher J. Harbort and Nathan McDonald and Lantian Gai and Huaming Chen and Yijian He and Jean Vandenhaute and Frederick P. Roth and David E. Hill and Joseph R. Ecker and Marc Vidal and Jim Beynon and Pascal Braun and Jeffery L. Dang and European Union Effectoromics Conso and European Union Effectoromics Consortium
Science (American Association for the Advancement of Science), ISSN 0036-8075, 7/2011, Volume 333, Issue 6042, pp. 596 - 601
Proteins | Pathogens | Receptors | RESEARCH ARTICLES | Arabidopsis proteins | Drug interactions | Virulence | Plant immunity | Connectivity | Infections | Host pathogen relationships | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Cell physiology | Cell biochemistry | Plant physiology and development | Plant Immunity | Genes, Plant | Plant Diseases - immunology | Arabidopsis - immunology | Immunity, Innate | Pseudomonas syringae - pathogenicity | Arabidopsis - metabolism | Protein Interaction Mapping | Arabidopsis - genetics | Host-Pathogen Interactions | Oomycetes - pathogenicity | Arabidopsis - microbiology | Bacterial Proteins - metabolism | Virulence Factors - metabolism | Receptors, Immunologic - metabolism | Evolution, Molecular | Physiological aspects | Plant defenses | Virulence (Microbiology) | Research | Health aspects | Immune system | Evolutionary biology | Flowers & plants | Convergence | Index Medicus | Life Sciences | Vegetal Biology
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7. Full Text High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities
by Hart, Traver and Chandrashekhar, Megha and Aregger, Michael and Steinhart, Zachary and Brown, Kevin R and MacLeod, Graham and Mis, Monika and Zimmermann, Michal and Fradet-Turcotte, Amelie and Sun, Song and Mero, Patricia and Dirks, Peter and Sidhu, Sachdev and Roth, Frederick P and Rissland, Olivia S and Durocher, Daniel and Angers, Stephane and Moffat, Jason
Cell (Cambridge), ISSN 0092-8674, 12/2015, Volume 163, Issue 6, pp. 1515 - 1526
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Gene Library | Humans | Bayes Theorem | CRISPR-Cas Systems | Cell Line, Tumor | Mutation | Gene Knockout Techniques | Genes, Essential | Pharmacy | Children's hospitals | Genes | Genomics | Drugstores | Genetic aspects | Phosphotransferases | Cells | Cancer | Index Medicus
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