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1. Full Text Multiple Trichilemmal Cysts of the Scalp
by Friedrich, Reinhard E and Wilczak, Waldemar
Anticancer research, ISSN 0250-7005, 08/2019, Volume 39, Issue 8, pp. 4253 - 4258
Different entities can be the cause of scalp neoplasia. In a phenotype with multiple cystic scalp lesions, the diagnosis must be made with particular caution... 
Skin Neoplasms - diagnostic imaging | Epidermal Cyst - surgery | Scalp - surgery | Neoplasms - surgery | Scalp - diagnostic imaging | Humans | Epidermal Cyst - diagnostic imaging | Neoplasms - diagnosis | Neoplasms - diagnostic imaging | Skin Neoplasms - physiopathology | Scalp - physiopathology | Skin Neoplasms - diagnosis | Epidermal Cyst - diagnosis | Adult | Epidermal Cyst - physiopathology | Female | Neoplasms - physiopathology | Skin Neoplasms - surgery | Phenotypes | Cysts | Scalp | Benign | Diagnosis | Lesions | Neoplasms | Tumors
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2. Full Text Non-odontogenic Intraosseous Radiolucent Lesions of the Mandibular Body Are Rare Findings on Panoramic Views of Patients With Neurofibromatosis Type 1
by Friedrich, RE and Scheuer, HT
ANTICANCER RESEARCH, ISSN 0250-7005, 04/2019, Volume 39, Issue 4, pp. 1971 - 1985
Background/Aim: The purpose of the study was to investigate whether non-odontogenic intraosseous translucent lesions of mandibular body are depicted on... 
ORAL MANIFESTATIONS | MULTIPLE NEUROFIBROMATOSIS | GIANT-CELL GRANULOMA | neurofibroma - intraosseous | DENTAL-CARIES | Neurofibromatosis type 1 | simple bone cavity | NF1 DIAGNOSIS | CHILDREN | RADIOLOGICAL FEATURES | FACIAL PLEXIFORM NEUROFIBROMA | ONCOLOGY | jaw - lesion | SOLITARY NEUROFIBROMA | panoramic view | Stafne's bone cavity | MAXILLA | Predictive Value of Tests | Radiography, Panoramic | Humans | Mandible - pathology | Middle Aged | Neurofibromatosis 1 - diagnostic imaging | Male | Mandibular Neoplasms - diagnostic imaging | Mandible - diagnostic imaging | Case-Control Studies | Young Adult | Neurofibromatosis 1 - pathology | Adolescent | Adult | Female | Aged | Mandibular Neoplasms - pathology | Child | Radiography | Jaw | Mandible | Statistical analysis | Radiographs | Neurofibromatosis | Radiology | Lesions | Recklinghausen's disease | Tumors
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3. Periapical Cemento-osseous Dysplasia Is Rarely Diagnosed on Orthopantomograms of Patients with Neurofibromatosis Type 1 and Is Not a Gender-specific Feature of the Disease
by Reinhard E Friedrich and Anika Reul
Anticancer Research, ISSN 0250-7005, 04/2018, Volume 38, Issue 4, p. 2277
Several skeletal aberrations of the skull have been described for the tumor predisposition syndrome neurofibromatosis type 1 (NF1). Recently, periapical... 
Jaw | Periodontics | Dysplasia | Neurofibromatosis | Plexiform neurofibroma | Teeth | Diagnostic systems | Gender | Females | Patients | Recklinghausen's disease | Tumors
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4. Expansive Extracranial Growth of Intracranial Meningioma in Neurofibromatosis Type 2
by Friedrich, Reinhard E and Hagel, Christian
Anticancer Research, ISSN 0250-7005, 06/2016, Volume 36, Issue 6, pp. 3161 - 3167
The purpose of this report is to detail three rare cases of neurofibromatosis type 2 (NF2) with symptomatic extracranial extension of intracranial meningioma.... 
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5. Full Text Unilaterally Enlarged Mandibular Foramina and Canal Associated With Hyperplastic Lymphatic Tissue of Inferior Alveolar Nerve: Case Report and Short Literature Survey
by Friedrich, RE and Matschke, J and Wilczak, W
ANTICANCER RESEARCH, ISSN 0250-7005, 08/2019, Volume 39, Issue 8, pp. 3991 - 4002
Background: Different phenomena can result in enlargement of mental foramen and mandibular canal. At the foreground of diagnosis is the assessment of the... 
magnetic resonance imaging | FOLLICULAR LYMPHOID HYPERPLASIA | PERINEURAL INVASION | alveolar nerve | SHEATH TUMOR | ORAL-CAVITY | Lymphatic hyperplasia | BEAM COMPUTED-TOMOGRAPHY | PANORAMIC RADIOGRAPHY | enlarged mandibular canal | MENTAL FORAMEN | ONCOLOGY | OSTEOGENIC-SARCOMA | NUMB CHIN SYNDROME | enlarged mental foramen | CRANIAL NERVES | Humans | Hyperplasia - surgery | Mandible - pathology | Mandible - diagnostic imaging | Mandibular Nerve - pathology | Lymphoid Tissue - diagnostic imaging | Hyperplasia - pathology | Mandibular Nerve - diagnostic imaging | Radiography | Lymphoid Tissue - pathology | Lymphoid Tissue - surgery | Hyperplasia - diagnostic imaging | Surveys and Questionnaires | Biological properties | Mandible | Hyperplasia | Canals | Exploration | Inflammation | Tissues | Diagnosis | Lesions | Alveoli | Expansion | Tumors | Enlargement
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6. Full Text Symptomatic Mandibular Fibrous Dysplasia With Concurrent Triple X- and Premutation Stage Fragile-X-Syndrome: Case Report With Short Literature Survey
by FRIEDRICH, REINHARD E and KOHLRUSCH, FELIX K and LUEBKE, ANDREAS M
Anticancer Research, ISSN 0250-7005, 12/2019, Volume 39, Issue 12, pp. 6769 - 6780
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7. Full Text Manifestations and treatment of adult-onset symptomatic optic pathway glioma in neurofibromatosis Type 1
by Mehlan, Juliane and Schüttauf, Frank and Salamon, Johannes M and Kordes, Uwe and Friedrich, Reinhard E and Mautner, Victor-Felix
Anticancer Research, ISSN 0250-7005, 02/2019, Volume 39, Issue 2, pp. 827 - 831
This report describes the diagnosis and treatment of a 27-year-old patient with neurofibromatosis 1 (NF1) and late progression of a pre-existing optic pathway... 
Chemotherapy | Neurofibromatosis type 1 | Optic pathway glioma | Vision | PRIMARY TUMORS | NERVE | RECKLINGHAUSENS-DISEASE | FOLLOW-UP | chemotherapy | RADIATION-THERAPY | CHILDREN | vision | ONCOLOGY | LOW-GRADE GLIOMA | VINCRISTINE | neurofibromatosis type 1 | OUTCOMES | Brain tumors | Central nervous system | Peripheral nerves | Recklinghausen's disease | Nodules | Osteoprotegerin | Glioma | Neurofibromatosis | Nerves | Carboplatin | Diagnostic systems | Skin | Diagnosis | Children | Neoplasia
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8. Full Text Osteoid Osteoma of the Mandible - Clinical and Histological Findings
by Matthies, Levi and Rolvien, Tim and Rolvien, Tim and Pakusa, Thomas J and Pakusa, Thomas J and Knipfer, Christian and Gosau, Martin and Amling, Michael and Friedrich, Reinhard E and Friedrich, Reinhard E and Zustin, Jozef
Anticancer research, ISSN 0250-7005, 01/2019, Volume 39, Issue 1, pp. 291 - 296
Background/Aim: Osteoid osteoma (OO) is a benign tumor characterized by the excessive formation of unmineralized bone matrix. It is mostly located in the long... 
cone beam CT | mandible | Osteoid osteoma | histology | bone tumor | OSTEOBLASTOMA | ONCOLOGY | OF-THE-LITERATURE | RADIOFREQUENCY ABLATION | Bone Neoplasms - diagnosis | Bone Neoplasms - diagnostic imaging | Humans | Mandible - pathology | Male | Tomography, X-Ray Computed | Mandible - diagnostic imaging | Neoplasms - diagnosis | Neoplasms - diagnostic imaging | Bone Neoplasms - pathology | Magnetic Resonance Imaging | Osteoma, Osteoid - pathology | Biopsy | Adolescent | Osteoma, Osteoid - diagnostic imaging | Osteoma, Osteoid - diagnosis | Neoplasms - pathology | Signs and symptoms | Mandible | Spine | Teeth | Osteoid | Bone growth | Pain | Osteoma | Bones | Biocompatibility | Bone | Bone matrix | Extremities | Tumors
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9. Unilateral Creeping Destruction of Deformed Mandibular Ramus and Angle Associated with Extensive Facial Plexiform Neurofibroma in Neurofibromatosis Type 1: A Case Report with Analysis of the Literature for Diagnosing Osteolytic Events of the Mandible in Tumor-suppressor Gene Syndrome
by Reinhard E Friedrich and Hanna A Scheuer
Anticancer Research, ISSN 0250-7005, 07/2018, Volume 38, Issue 7, p. 4083
Neurofibromatosis type (NF1) is an autosomal dominant inherited tumor-suppressor gene syndrome of significant phenotypic variability with probable complete... 
Phenotypes | Mandible | Genetic variability | Destruction | Deformation mechanisms | Pathogenesis | Plexiform neurofibroma | Osteolysis | Recklinghausen's disease | Calvaria | Neurofibromatosis | Biocompatibility | Skull | Bone | Tumors
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10. Full Text Ponticulus posticus is a frequent radiographic finding on lateral Cephalograms in nevoid basal cell carcinoma syndrome (Gorlin-Goltz Syndrome)
by Friedrich, Reinhard E
Anticancer Research, ISSN 0250-7005, 12/2014, Volume 34, Issue 12, pp. 7395 - 7399
Nevoid basal cell carcinoma syndrome (NBCCS) is a predisposition to a rare tumor type with a variable phenotype. Besides tumors, skeletal alterations, such as... 
Ponticulus posticus | Phacomatosis | Atlanto-occipital ligament | Calcification | Gorlin-Goltz syndrome | Lateral cephalogram | Arcuate foramen | Nevoid basal cell carcinoma syndrome | DIAGNOSIS | atlanto-occipital ligament | lateral cephalogram | phacomatosis | PREVALENCE | ATLAS | RADIOLOGICAL FEATURES | ONCOLOGY | ponticulus posticus | calcification | VERTEBRAL ARTERY | arcuate foramen | Ossification, Heterotopic - pathology | Humans | Middle Aged | Child, Preschool | Ossification, Heterotopic - diagnostic imaging | Calcinosis - diagnostic imaging | Male | Bone Development | Radiography | Basal Cell Nevus Syndrome - pathology | Cervical Atlas - pathology | Cervical Atlas - diagnostic imaging | Adult | Female | Aged | Calcinosis - pathology | Basal Cell Nevus Syndrome - diagnostic imaging | Child
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11. Full Text Mucoepidermoid carcinoma-Unknown primary affecting the neck
by Friedrich, Reinhard E and Zustin, Jozef
Anticancer Research, ISSN 0250-7005, 06/2016, Volume 36, Issue 6, pp. 3169 - 3171
The present report describes therapy and followup of a patient who experienced a localized swelling of the neck that proved to be a mucoepidermoid carcinoma.... 
Carcinoma unknown primary | Radiotherapy head neck | Mucoepidermoid carcinoma | Neck metastasis | Salivary gland neoplasm | radiotherapy head neck | HEAD | neck metastasis | ONCOLOGY | salivary gland neoplasm | SALIVARY-GLAND ORIGIN | carcinoma unknown primary | Lymph Node Excision | Carcinoma, Mucoepidermoid - therapy | Humans | Middle Aged | Neoplasms, Unknown Primary - therapy | Male | Combined Modality Therapy | Neck
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12. Full Text Distinctive low epidermal nerve fiber density in schwannomatosis patients provides a major parameter for diagnosis and differential diagnosis
by Farschtschi, Said C and Kluwe, Lan and Schön, Gerhard and Friedrich, Reinhard E and Matschke, Jakob and Glatzel, Markus and Hagel, Christian and Mautner, Victor-Felix
Brain pathology (Zurich, Switzerland), ISSN 1015-6305, 08/2019
Schwannomatosis and neurofibromatosis type 2 (NF2) are two distinct neuro-genetic tumor predisposition disorders which however share some clinical and genetic... 
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13. Full Text Periapical cemento-osseous dysplasia is rarely diagnosed on orthopantomograms of patients with neurofibromatosis type 1 and is not a gender-specific feature of the disease
by Friedrich, Reinhard E and Reul, Anika
Anticancer Research, ISSN 0250-7005, 04/2018, Volume 38, Issue 4, pp. 2277 - 2284
Several skeletal aberrations of the skull have been described for the tumor predisposition syndrome neurofibromatosis type 1 (NF1). Recently, periapical... 
Cemento-osseous dysplasia | Neurofibromatosis type 1 | Periapical cemental dysplasia | Gender difference | periapical cemental dysplasia | cemento-osseous dysplasia | MANAGEMENT | OSSIFYING FIBROMAS | BENIGN FIBROOSSEOUS LESIONS | DEFORMITIES | gender difference | BEAM COMPUTED-TOMOGRAPHY | JAWS | RADIOGRAPHIC FEATURES | ONCOLOGY | PLEXIFORM NEUROFIBROMA | NF1 | SPECTRUM
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14. Full Text Pilomatrixoma of the Neck/Shoulder Region Mimicking a Rapidly Growing Neoplasm of Peripheral Nerve Sheath Origin in Neurofibromatosis Type 1
by Friedrich, Reinhard E and Schüller, Ulrich and Hagel, Christian
Anticancer research, ISSN 0250-7005, 12/2017, Volume 37, Issue 12, pp. 6907 - 6910
Neurofibromatosis type 1 (NF1) is an autosomal dominant hereditary disorder. Neurofibroma is the most common neoplasm of this disease. This lesion is... 
Neurofibromatosis type 1 | malignant peripheral nerve sheath tumor | pilomatrixoma | peripheral nerve sheath tumor | HEAD | ONCOLOGY | EPIDERMAL CYST | TUMORS
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15. Full Text Clinical and Microstructural Findings in Paget Disease of the Entire Mandible
by Friedrich, Reinhard E and Luebke, Andreas M and Amling, Michael and Koehne, Till
Journal of Oral and Maxillofacial Surgery, ISSN 0278-2391, 02/2018, Volume 76, Issue 2, pp. 336 - 346
Paget disease of bone (PDB) is a chronic progressive bone disorder characterized by localized increased bone turnover and focal areas of woven bone formation.... 
TEETH | BONE | SIGN | DENTISTRY, ORAL SURGERY & MEDICINE | Radiography, Panoramic | Diagnosis, Differential | Mandibular Diseases - diagnostic imaging | Osteitis Deformans - diagnostic imaging | Osteitis Deformans - pathology | Biopsy | Humans | Radionuclide Imaging | Female | Mandibular Diseases - pathology | Tomography, X-Ray Computed | Aged
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16. Full Text Vitamin D receptor expression and serum 25D concentration inversely associates with burden of neurofibromas
by Kluwe, Lan and Hagel, Christian and Friedrich, Reinhard E and Schnabel, Claudia and Schon, Gerhard and Mautner, Victor
European Journal of Cancer Prevention, ISSN 0959-8278, 05/2019, Volume 28, Issue 3, p. 220
Vitamin D and its receptor may play a role in preventing tumor development and progression. As such antineoplastic effects are expected to be weak and to act... 
Prevention | Vitamin D | Physiological aspects | Calcifediol | Development and progression | Alfacalcidol | Health aspects | Neurofibroma
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17. Recurrent Maxillary Odontogenic Myxoma Following Partial Maxillary Resection and Consecutive Osseous Reconstruction Including Tooth Transplantation
by Friedrich, Reinhard E and Scheuer, Hanna A and Holtje, Wolf
Anticancer Research, ISSN 0250-7005, 06/2016, Volume 36, Issue 6, pp. 3155 - 3160
Odontogenic myxoma (OM) is a rare tumour arising in the jaws. The tumour is purported to be odontogenic in origin due to the frequent localisation of the... 
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18. Full Text Unilateral creeping destruction of deformed mandibular ramus and angle associated with extensive facial plexiform neurofibroma in neurofibromatosis type 1: A case report with analysis of the literature for diagnosing osteolytic events of the mandible in tumor-suppressor gene syndrome
by Friedrich, Reinhard E and Scheuer, Hanna A
Anticancer Research, ISSN 0250-7005, 07/2018, Volume 38, Issue 7, pp. 4083 - 4091
Neurofibromatosis type (NF1) is an autosomal dominant inherited tumor-suppressor gene syndrome of significant phenotypic variability with probable complete... 
Bone deformity | Mandible | Neurofibromatosis type 1 | Gorham-Stout syndrome | Plexiform neurofibroma | GIANT-CELL GRANULOMA | TIBIAL PSEUDOARTHROSIS | bone deformity | ORAL FINDINGS | NOONAN-SYNDROME | MASSIVE OSTEOLYSIS | CHILDREN | ONCOLOGY | mandible | NF1 | BONE | DESCRIPTIVE ANALYSIS | plexiform neurofibroma
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19. Full Text Expression of the insulin-like growth factor-1 receptor in odontogenic myxoma
by Friedrich, Reinhard E and Hagel, Christian and Zustin, Jozef
Anticancer Research, ISSN 0250-7005, 06/2016, Volume 36, Issue 6, pp. 3103 - 3107
Odontogenic myxoma (OM) is a rare mesenchymal tumour arising in the jaws. The origin and pathogenesis of OM is poorly understood. The aim of this study was to... 
Immunohistochemistry | Rare tumours | Odontogenic myxoma | IGF-1R | Odontogenic tumour | FACTOR-SYSTEM | RAT | IMMUNOHISTOCHEMICAL LOCALIZATION | PODOPLANIN | TISSUE | COMPONENTS | TEETH | TUMORS | NESTIN EXPRESSION | odontogenic tumour | STEM-CELLS EXPRESS | ONCOLOGY | immunohistochemistry | rare tumours | AC133 Antigen - analysis | Receptor, IGF Type 1 - analysis | Odontogenic Tumors - chemistry | Nestin - analysis | Myxoma - chemistry | Humans
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20. Full Text Recurrent maxillary odontogenic myxoma following partial maxillary resection and consecutive osseous reconstruction including tooth transplantation
by Friedrich, Reinhard E and Scheuer, Hanna A and Höltje, Wolf
Anticancer Research, ISSN 0250-7005, 06/2016, Volume 36, Issue 6, pp. 3155 - 3160
Odontogenic myxoma (OM) is a rare tumour arising in the jaws. The tumour is purported to be odontogenic in origin due to the frequent localisation of the... 
Tooth transplantation | Tumour recurrence | Jaw tumour | Displaced permanent tooth | Odontogenic myxoma | jaw tumour | tooth transplantation | CONVENTIONAL RADIOGRAPHS | displaced permanent tooth | CHINESE | TUMORS | COMPUTED-TOMOGRAPHY | CELL CARCINOMA | FEATURES | JAWS | ONCOLOGY | MUTATIONS | OF-THE-LITERATURE | tumour recurrence | Maxillary Neoplasms - surgery | Odontogenic Tumors - surgery | Myxoma - surgery | Humans | Reconstructive Surgical Procedures - methods | Female | Maxilla - surgery | Odontogenic Tumors - etiology | Tooth - transplantation | Child | Neoplasm Recurrence, Local - etiology | Myxoma - etiology
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