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Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 14691 - 9
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 1213 - 1213
Radiotherapy is used in the treatment of ~50% of tumors. We and others have reported long-term suppression of hematopoietic stem and progenitor cells (HSPCs)... 
Journal Article
Bone, ISSN 8756-3282, 02/2019, Volume 119, pp. 8 - 12
Hematopoietic stem cells (HSCs) require a supportive microenvironment to regulate their function and produce sufficient hematopoietic cells over the lifetime... 
Hematopoiesis | HSC | Niche | OSTEOCYTES | MOBILIZATION | SELF-RENEWAL | RADIATION SENSITIVITY | SUPPORT | IMMUNE-SYSTEM | INCREASE | OSTEOBLASTS | ENDOCRINOLOGY & METABOLISM | FISH | EXPRESSION
Journal Article
International Journal of Radiation Biology, ISSN 0955-3002, 11/2019, Volume 95, Issue 11, pp. 1447 - 1461
Purpose: Incidents, such as nuclear facility accidents and the release of a 'dirty bomb', might result in not only external irradiation of personnel, but... 
bone marrow late effects | Hematopoiesis | combined radiation injury | internal contamination | Index Medicus | Space life sciences
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 1482 - 1482
Abstract Background/Rationale: Hematologic malignancies are known to remodel the bone marrow microenvironment, reducing support for normal hematopoiesis while... 
Journal Article
Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 1199 - 1199
Abstract The bone marrow microenvironment, including osteolineage cells, regulates hematopoietic stem cell (HSC) fate choices. Intermittent pharmacologic... 
Journal Article
Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 358 - 358
Abstract While data suggest that, in the myelodysplastic syndromes (MDS), the bone marrow microenvironment (BMME) is abnormal, the lack of examination of the... 
Journal Article
Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. 4359 - 4359
Abstract In vitro data provide evidence of an altered bone marrow microenvironment (BMME) in the myelodysplastic syndromes (MDS). To assess the role of the... 
Journal Article
Blood, ISSN 0006-4971, 11/2013, Volume 122, Issue 21, pp. 2756 - 2756
Abstract Myelodysplastic Syndromes (MDS) are a group of clonal disorders characterized by ineffective hematopoiesis. Recently, data have emerged supporting a... 
Journal Article
International journal of radiation biology, 07/2019, p. 1
: Incidents, such as nuclear facility accidents and the release of a 'dirty bomb', might result in not only external irradiation of personnel, but additional... 
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 04/2018, Volume 26, Issue 7, pp. 1365 - 1373
Journal Article
Blood, ISSN 0006-4971, 11/2011, Volume 118, Issue 21, pp. 243 - 243
Abstract Abstract 243 Disruption of normal hematopoietic development is a major problem in acute myeloid leukemia (AML). Osteoblastic cells have been shown to... 
Journal Article
Blood, ISSN 0006-4971, 11/2012, Volume 120, Issue 21, pp. 642 - 642
Abstract Abstract 642 HSCs are rare immature cells capable of reconstituting all blood cell lineages throughout the life of an individual. We have previously... 
Journal Article
Blood, ISSN 0006-4971, 11/2010, Volume 116, Issue 21, pp. 1219 - 1219
Abstract Abstract 1219 Patients with myelogenous leukemias can present with symptoms of bone pain and pathologic fractures, however little is known about the... 
Journal Article
Journal Article
Blood, ISSN 0006-4971, 01/2012, Volume 119, Issue 2, pp. 540 - 550
Journal Article
Journal Article
Blood, ISSN 0006-4971, 11/2009, Volume 114, Issue 22, pp. 1449 - 1449
Abstract Abstract 1449 Poster Board I-472 Osteoblastic cells have been identified as a component of the hematopoietic stem cell (HSC) niche. This... 
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 06/2017, Volume 32, Issue 6, pp. 1320 - 1331
ABSTRACT Notch signaling is critical for osteoblastic differentiation; however, the specific contribution of individual Notch ligands is unknown. Parathyroid... 
NOTCH | OSTEOBLAST | STROMAL/STEM CELL | GENETIC ANIMAL MODELS | PARATHYROID HORMONE | BONE-MARROW NICHE | FACTOR RBP-J | SELF-RENEWAL | INDUCED OSTEOCLASTOGENESIS | TRABECULAR BONE | HEMATOPOIETIC STEM-CELLS | ENDOCRINOLOGY & METABOLISM | MICE | DIFFERENTIATION | NF-KAPPA-B | EXPRESSION | Jagged-1 Protein - metabolism | Cancellous Bone - metabolism | Growth Plate - diagnostic imaging | Cell Count | Parathyroid Hormone - pharmacology | Stem Cells - cytology | Osteoclasts - cytology | Stem Cells - metabolism | Cell Lineage - drug effects | X-Ray Microtomography | Cancellous Bone - cytology | Cancellous Bone - diagnostic imaging | Growth Plate - cytology | Bone Resorption - metabolism | Osteoblasts - cytology | Osteoblasts - drug effects | Osteogenesis - drug effects | Growth Plate - metabolism | Osteoclasts - metabolism | Animals | Cell Differentiation - drug effects | Models, Biological | Bone Resorption - pathology | Stem Cells - drug effects | Ligands | Mice | Osteoblasts - metabolism | Osteoclasts - drug effects | Bones | Parathyroid hormone | Density | Analysis | Stem cells | Osteoprogenitor cells | Flow cytometry | Mesenchyme | Homeostasis | Bone (trabecular) | CD45 antigen | Apposition | Bone resorption | Functional anatomy | Clonal deletion | Ataxin | Rodents | Skeleton | Jagged1 protein | Parathyroid | Age | Limbs | Bone turnover | Cre recombinase | Progeny | Bone mass | Osteoblastogenesis | Notch protein | STEM CELL | STROMAL
Journal Article