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1. Full Text Comparative analyses of long non-coding RNA profiles in vivo in cystic fibrosis lung airway and parenchyma tissues
by Kumar, Parameet and Sen, Chaitali and Peters, Kathryn and Frizzell, Raymond A and Biswas, Roopa
Respiratory research, ISSN 1465-993X, 12/2019, Volume 20, Issue 1, pp. 284 - 284
Life Sciences & Biomedicine | Respiratory System | Science & Technology | Deregulation | Disease | Gene regulation | Parenchyma | mRNA | Tissue analysis | Tissues | Proteins | Respiratory tract | Genotype & phenotype | Protein folding | Penicillin | Chronic obstructive pulmonary disease | Phenotypes | Statistical analysis | Cytokines | Therapeutic applications | Lung diseases | Cystic fibrosis | Bronchiectasis | Cell membranes | Inflammation | Roles | RNA polymerase | Ribonucleic acid--RNA | Gene expression | Clustering | Epithelium | Disease control | Asthma | DNA microarrays | Lungs | Fibrosis | Epigenetics | Software | Mutation | Cystic fibrosis transmembrane conductance regulator | Non-coding RNA | Chemokines | Index Medicus | long non-coding RNA | lung disease | F508del-CFTR | Research
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2. SUMOylation modulates CFTR biogenesis: Is the pathway druggable?
by Ahner, Annette and Frizzell, Raymond A
Current drug targets, ISSN 1389-4501, 09/2015, Volume 16, Issue 9, pp. 965 - 975
SUMO interaction motif (SIM) | SUMO | SAE1/SAE2 | Hsp27 | SUMOpeptidases | SUMO E3 | Ubc9 | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Small Molecule Libraries - pharmacology | Cystic Fibrosis - metabolism | Small Ubiquitin-Related Modifier Proteins - metabolism | Humans | Small Molecule Libraries - therapeutic use | Clinical Trials as Topic | Cystic Fibrosis Transmembrane Conductance Regulator - metabolism | Molecular Targeted Therapy | Sumoylation - drug effects | Signal Transduction - drug effects | Cystic Fibrosis - genetics | Cystic Fibrosis Transmembrane Conductance Regulator - genetics | Cystic Fibrosis - drug therapy
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3. Full Text Regulation of the epithelial sodium channel by membrane trafficking
by Michael B. Butterworth and Robert S. Edinger and Raymond A. Frizzell and John P. Johnson
American Journal of Physiology - Renal Physiology, ISSN 1931-857X, 01/2009, Volume 296, Issue 1, pp. 10 - 24
Deubiquitination | Clathrin-mediated endocytosis | Vesicle recycling | Physiology | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Epithelial Cells - physiology | Transport Vesicles - physiology | Humans | Protein Transport - physiology | Cell Membrane - physiology | Epithelial Cells - cytology | Epithelial Sodium Channels - physiology | Exocytosis - physiology | Membranes | Hormones | Sodium | Tissues | Cells | Index Medicus | deubiquitination | Reviews | vesicle recycling | clathrin-mediated endocytosis
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4. Full Text Divergent signaling via SUMO modification: Potential for CFTR modulation
by Ahner, Annette and Gong, Xiaoyan and Frizzell, Raymond A
American Journal of Physiology: Cell Physiology, ISSN 0363-6143, 2016, Volume 310, Issue 3, pp. C175 - C180
SUMO ligase | Ubc9 (SUMO-conjugating enzyme) | Multi-SUMOylation | SUMO-specific peptidase | SIM (SUMO-interacting motif) | Physiology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Genetic Predisposition to Disease | Cystic Fibrosis - metabolism | Humans | Nuclear Proteins - metabolism | Cystic Fibrosis Transmembrane Conductance Regulator - metabolism | Transcription Factors - metabolism | Phenotype | Animals | Proteolysis | Cystic Fibrosis - genetics | Sumoylation | Cystic Fibrosis Transmembrane Conductance Regulator - genetics | SUMO-1 Protein - metabolism | Mutation | Proteasome Endopeptidase Complex - metabolism | Protein Stability | Respiratory Mucosa - metabolism | Physiological aspects | Heat shock proteins | Cystic fibrosis | Cyclic adenylic acid | Observations | Health aspects | Protein-protein interactions | Membranes | Protein folding | Index Medicus | Hugh Davson Distinguished Lectureship of the Cell and Molecular Physiology Section, 2014 | Ubc9 (SUMO-conjugating enzyme), multi-SUMOylation
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5. Full Text A Combination Therapy for Cystic Fibrosis
by Brodsky, Jeffrey L and Frizzell, Raymond A
Cell (Cambridge), ISSN 0092-8674, 09/2015, Volume 163, Issue 1, pp. 17 - 17
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | History, 21st Century | History, 20th Century | Humans | Cystic Fibrosis - history | Aminophenols - therapeutic use | Cystic Fibrosis Transmembrane Conductance Regulator - metabolism | Aminopyridines - therapeutic use | Cystic Fibrosis - genetics | Gene Deletion | Quinolones - therapeutic use | Cystic Fibrosis Transmembrane Conductance Regulator - genetics | Benzodioxoles - therapeutic use | Cystic Fibrosis - drug therapy | Drug Combinations | Cystic fibrosis | Care and treatment | Cells | Medical colleges | Index Medicus
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6. Full Text Cystic fibrosis transmembrane conductance regulator degradation: cross‐talk between the ubiquitylation and SUMOylation pathways
by Ahner, Annette and Gong, Xiaoyan and Frizzell, Raymond A
The FEBS journal, ISSN 1742-464X, 09/2013, Volume 280, Issue 18, pp. 4430 - 4438
proteasome | small heat shock proteins | quality control | Hsp27 | small ubiquitin‐like modifier | STUbL | cystic fibrosis transmembrane conductance regulator | endoplasmic reticulum associated | degradation | ubiquitin | small ubiquitin-like modifier | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Humans | Cystic Fibrosis - pathology | HSP27 Heat-Shock Proteins - genetics | Ubiquitination | Proteolysis | Nuclear Proteins - genetics | Signal Transduction | Cystic Fibrosis - metabolism | Nuclear Proteins - metabolism | Ubiquitin-Conjugating Enzymes - genetics | Cystic Fibrosis Transmembrane Conductance Regulator - metabolism | Transcription Factors - genetics | Cystic Fibrosis Transmembrane Conductance Regulator - chemistry | Protein Folding | Protein Transport | Proteasome Endopeptidase Complex - genetics | Transcription Factors - metabolism | Ubiquitin-Conjugating Enzymes - metabolism | Cystic Fibrosis - genetics | HSP27 Heat-Shock Proteins - metabolism | Sumoylation | Cystic Fibrosis Transmembrane Conductance Regulator - genetics | Protein Processing, Post-Translational | Mutation | Proteasome Endopeptidase Complex - metabolism | Ubiquitin | Heat shock proteins | Cystic fibrosis | Biosynthesis | Index Medicus
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7. Full Text Acute ENaC stimulation by cAMP in a kidney cell line is mediated by exocytic insertion from a recycling channel pool
by Butterworth, Michael B and Edinger, Robert S and Johnson, John P and Frizzell, Raymond A
The Journal of general physiology, ISSN 0022-1295, 01/2005, Volume 125, Issue 1, pp. 81 - 101
Cellular traffic | Short-circuit current | Capacitance | Biotinylation | Recycle | Kidney - physiology | Cell Line | Kidney - drug effects | Colforsin - pharmacology | Membrane Potentials - physiology | Exocytosis - physiology | Exocytosis - drug effects | Epithelial Sodium Channels | Ion Channel Gating - physiology | Animals | Models, Biological | Computer Simulation | Sodium Channels - metabolism | Mice | Cyclic AMP - metabolism | Sodium channels | Cells | Research | Electrical currents | Membranes | Kidneys | Sodium | Ions | Biochemistry | Index Medicus | recycle | biotinylation | capacitance | cellular traffic | short-circuit current
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8. Full Text SLC26A9 is a constitutively active, CFTR-regulated anion conductance in human bronchial epithelia
by Bertrand, Carol A and Zhang, Ruilin and Pilewski, Joseph M and Frizzell, Raymond A
The Journal of general physiology, ISSN 0022-1295, 04/2009, Volume 133, Issue 4, pp. 421 - 438
Life Sciences & Biomedicine | Physiology | Science & Technology | Cystic Fibrosis Transmembrane Conductance Regulator - antagonists & inhibitors | Cell Line | Voltage-Dependent Anion Channels - physiology | Bronchi - enzymology | Respiratory Mucosa - cytology | Humans | Respiratory Mucosa - enzymology | Cystic Fibrosis Transmembrane Conductance Regulator - physiology | Antiporters - metabolism | Chloride Channels - metabolism | Cyclic AMP - physiology | Cyclic AMP-Dependent Protein Kinases - physiology | Ion Channel Gating - physiology | Bronchi - metabolism | Respiratory Mucosa - physiology | Bronchi - physiology | Respiratory Mucosa - metabolism | Antiporters - physiology | Bronchi - cytology | Chloride Channels - physiology | Voltage-Dependent Anion Channels - metabolism | Anions | Electrical conductivity | Epithelial cells | Bronchi | Cellular control mechanisms | Cystic fibrosis | Chloride channels | Research | Properties | Membranes | Bronchitis | ABC transporters | Cells | Index Medicus
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9. Full Text Functional and molecular identification of a TASK-1 potassium channel regulating chloride secretion through CFTR channels in the shark rectal gland: Implications for cystic fibrosis
by Telles, Connor J and Decker, Sarah E and Motley, William W and Peters, Alexander W and Mehr, Ali Poyan and Frizzel, Raymond A and Forrest, John N
American Journal of Physiology: Cell Physiology, ISSN 0363-6143, 2016, Volume 311, Issue 6, pp. C884 - C894
channel | Task-1 K | Shark rectal gland | Cystic fibrosis transmembrane conductance regulator | Four transmembrane two pore | Physiology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Potassium Channels, Tandem Pore Domain - metabolism | Amino Acid Sequence | Sharks - metabolism | Cystic Fibrosis - metabolism | Oocytes - metabolism | Humans | DNA, Complementary - genetics | Potassium Channels, Tandem Pore Domain - genetics | Salt Gland - metabolism | Dogfish - metabolism | Cystic Fibrosis Transmembrane Conductance Regulator - metabolism | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Potassium Channels - metabolism | Animals | Chlorides - metabolism | Xenopus laevis - genetics | Physiological aspects | Cystic fibrosis | Potassium channels | Health aspects | Protein-protein interactions | Molecules | Chloride | Potassium | Sharks | Index Medicus | shark rectal gland | cystic fibrosis transmembrane conductance regulator | four transmembrane two pore | task-1 K+ channel
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