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Journal Article
Trends in Biochemical Sciences, ISSN 0968-0004, 11/2014, Volume 39, Issue 11, p. 510
  Pore-forming proteins (PFPs) interact with lipid bilayers to compromise membrane integrity. Many PFPs function by inserting a ring of oligomerized subunits... 
Proteins | Membranes | Peptides | Lipids
Journal Article
PLoS Pathogens, ISSN 1553-7366, 01/2013, Volume 9, Issue 1
  Human γ9δ2 T cells potently inhibit pathogenic microbes, including intracellular mycobacteria, but the key inhibitory mechanism(s) involved have not been... 
Proteins | Vaccines | Lymphocytes | Autophagy | Apoptosis
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 10/2002, Volume 72, Issue 4, pp. 668 - 676
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2011, Volume 6, Issue 9, pp. e24286 - e24286
The cytotoxic cell granule secretory pathway is essential for host defense. This pathway is fundamentally a form of intracellular protein delivery where... 
CYTOSOLIC DELIVERY | MECHANISM | TARGET-CELLS | MULTIDISCIPLINARY SCIENCES | DEATH | PORE-FORMING PROTEIN | EQUINATOXIN-II | GRANULES | CYTOTOXICITY | GRANZYME-B | LYMPHOCYTES | Granzymes - pharmacology | Apoptosis - drug effects | Humans | Extracellular Space - drug effects | Propidium - metabolism | Exocytosis - drug effects | T-Lymphocytes, Cytotoxic - drug effects | Extracellular Space - metabolism | Time Factors | Cattle | Cell Membrane - metabolism | Cell Membrane - drug effects | Biomarkers - metabolism | Calcium - pharmacology | Cholesterol - deficiency | Jurkat Cells | Phosphatidylserines - metabolism | Perforin - isolation & purification | Ions | Epitopes | Cholesterol - metabolism | Annexin A5 - metabolism | Animals | T-Lymphocytes, Cytotoxic - metabolism | Models, Biological | Sheep | Mice | Perforin - metabolism | HeLa Cells | Perforin - pharmacology | Oligomers | Antigens | Proteases | Analysis | Phospholipids | Cell membranes | Apoptosis | Membranes | CD8 antigen | Cytotoxicity | Lipids | Propidium iodide | Monomers | Proteins | Biological effects | Granzyme B | Lymphocytes | Perforin | Phosphatidylserine | Recombinant | Oligomerization | Iodides | Electron microscopy | Cholesterol | Chromatography | Medicine | Granular materials | Endopeptidase | Pores | Serine proteinase | Porosity | Curvature | Pore formation | Tumors | Index Medicus
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2011, Volume 108, Issue 52, pp. 21016 - 21021
Journal Article